Abstract: According to some embodiments of the invention there is provided a colon cleaning system comprising: a working channel, a vacuum source, a separate vacuum pipe provided alongside the working channel, and a sensor positioned at a conduit connected externally to the working channel, the sensor configured for providing an indication related to pressure within at least a segment of the working channel. In some embodiments, the system comprises a controller configured for controlling one or more parameters of a vacuum induced in the separate vacuum pipe, the parameter determined according to the pressure related indication provided by the sensor.

Abstract: Systems and methods for cleaning a colon or other portion of an intestine include optional use of sensors to detect conditions of blockage of flow of materials within an evacuation channel used to remove fecal material from the body; and devices and methods for purging such blockages from the evacuation channel.

Abstract: According to some embodiments of the invention there is provided a colon cleaning system comprising: a working channel, a vacuum source, a separate vacuum pipe provided alongside the working channel, and a sensor positioned at a conduit connected externally to the working channel, the sensor configured for providing an indication related to pressure within at least a segment of the working channel. In some embodiments, the system comprises a controller configured for controlling one or more parameters of a vacuum induced in the separate vacuum pipe, the parameter determined according to the pressure related indication provided by the sensor.

Abstract: This application presents methods and devices for continuously cleaning a colon by at least partially filling a segment of the colon with liquid and agitating the fluid to dislodge matter adhering to the colon walls. Methods for automatic maintenance of liquid levels in the colon during continuous cleaning are taught.

Abstract: An inflatable flotation device having a reaction chamber with reactants that generate gas when mixed, said reactants being separated by a barrier assembly; an activating mechanism adapted to remove or puncture the barrier assembly such that said reactants mix; and an inflatable compartment fluidly connected to the reaction chamber by means of a pressure sensitive passageway, adapted to open only when the pressure of the gas in said reaction chamber exceeds a predetermined threshold. This ensures that most of the reactants are used up to generate gas before the gas enters the inflatable chamber, thus preventing scattering of the reactants. Some implementations have a reaction chamber without a barrier assembly, comprising reactants that generate gas when mixed with water and an activating mechanism adapted to expose the reactants to water. A variety of manual or automatic mechanisms may be employed to activate the reaction and inflate the device.

Abstract: Methods of colon cleansing and/or inspection are described which safely maintain a colon in an uncollapsed state. Balanced replacement of a volume of fluid, gas and/or solids evacuated during cleansing of the colon is described. Replacement volume comprises, for example, cleansing fluid, jetting gas, and/or inflation gas. In some embodiments, balancing of evacuated and replacement volume is achieved under automatic control, based on monitored volume of material exchange, and/or measurement of resulting pressures.

Abstract: Methods for clearing of fecal matter the wall of a colon or other body lumen for diagnostic inspection, the methods being adapted to clearing of fecal matter comprised of particles of various sizes and compositions. Methods are further adapted for application in patients who have undergone a restricted scope of preparation to reduce and/or remediate the particle structure of colon contents, or no preparation at all, before diagnostic inspection.

Abstract: Systems comprising a needle assembly configured to be inserted and steered within the brain, body tissue, or cavity, for the purpose of performing a surgical procedure. The needle assembly comprises robotically controlled and motorized concentric cannulas. For bending, there may be provided, for example, a tensioning wire configured to bend an inner cannula, or a cannula with an adjustable natural curve. A flexible inner element passing through the bend of the inner cannula is made self-straightening to minimize susceptibility to displacement from its intended path as it is advanced through the tissue. The self-straightening inner element comprises, for example, at least one of a super-elastic tube, a shape-memory alloy tube, a slotted tube, a tightly coiled memory alloy spring, circular links held together by pulling cables preloaded by springs, and a notched inner cannula with a cable connected via a loaded spring to tension the inner cannula.

Abstract: Systems and methods for cleaning a colon or other portion of an intestine include optional use of sensors to detect conditions of blockage of flow of materials within an evacuation channel used to remove fecal material from the body; and devices and methods for purging such blockages from the evacuation channel.

Abstract: Systems and methods for cleaning a colon or other portion of an intestine include optional use of sensors to detect conditions of blockage of flow of materials within an evacuation channel used to remove fecal material from the body; and devices and methods for purging such blockages from the evacuation channel.

Abstract: Devices for joining an endoscope with a system for cleaning a colon or other body lumen are presented. Embodiments include variable placement of distal portions of suction components with respect to the endoscope, multiple suction tubes and/or suction portals, and devices for protecting colon walls from suction damage.

Abstract: A sleeve assembly is described for coupling a colonoscope insertion tube to an add-on tube. In some embodiments, the sleeve assembly defines an elongated lumen and comprises an inner sleeve sized to receive an insertion tube of a colonoscope, an outer sleeve encircling the inner sleeve, and one or more add-on tubes positioned between the inner sleeve and the outer sleeve. In some embodiments, at least the inner sleeve is collapsible to fit tightly over a colonoscope insertion tube received within the inner sleeve. In some embodiments, the inner sleeve is coupled to the outer sleeve at one or more locations along the length of the inner sleeve so that collapsing of the inner sleeve brings the outer sleeve radially closer to the inner sleeve, approximating the one or more add-on tubes to a colonoscope insertion tube received within the inner sleeve.

Abstract: Devices for joining an endoscope with a system for cleaning a colon or other body lumen are presented. Embodiments include variable placement of distal portions of suction components with respect to the endoscope, multiple suction tubes and/or suction portals, and devices for protecting colon walls from suction damage.

Abstract: An inflatable flotation device having a reaction chamber with reactants that generate gas when mixed, said reactants being separated by a barrier assembly; an activating mechanism adapted to remove or puncture the barrier assembly such that said reactants mix; and an inflatable compartment fluidly connected to the reaction chamber by means of a pressure sensitive passageway, adapted to open only when the pressure of the gas in said reaction chamber exceeds a predetermined threshold. This ensures that most of the reactants are used up to generate gas before the gas enters the inflatable chamber, thus preventing scattering of the reactants. Some implementations have a reaction chamber without a barrier assembly, comprising reactants that generate gas when mixed with water and an activating mechanism adapted to expose the reactants to water. A variety of manual or automatic mechanisms may be employed to activate the reaction and inflate the device.

Abstract: According to some embodiments of the invention there is provided a colon cleaning system comprising: a working channel, a vacuum source, a separate vacuum pipe provided alongside the working channel, and a sensor positioned at a conduit connected externally to the working channel, the sensor configured for providing an indication related to pressure within at least a segment of the working channel. In some embodiments, the system comprises a controller configured for controlling one or more parameters of a vacuum induced in the separate vacuum pipe, the parameter determined according to the pressure related indication provided by the sensor.

Abstract: According to some embodiments of the invention there is provided a colon cleaning system comprising: a working channel, a vacuum source, a separate vacuum pipe provided alongside the working channel, and a sensor positioned at a conduit connected externally to the working channel, the sensor configured for providing an indication related to pressure within at least a segment of the working channel. In some embodiments, the system comprises a controller configured for controlling one or more parameters of a vacuum induced in the separate vacuum pipe, the parameter determined according to the pressure related indication provided by the sensor.

Abstract: Methods of colon cleansing and/or inspection are described which safely maintain the colon in an uncollapsed state. Balanced replacement of the volume of fluid, gas and/or solids evacuated during cleansing of a colon is described. Replacement volume comprises, for example, cleansing fluid, jetting gas, and/or inflation gas. In some embodiments, the balancing of evacuated and replacement volume is achieved under automatic control, based on monitored volume of material exchange, and/or measurement of resulting pressures.

Abstract: A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, the end ones of which expand at least radially when inflated. Connecting passages provide fluid communication between each pair of adjacent chambers. A fluid source is attached to one of the end chambers. The connecting passages are such that the fluid inflates the chambers in a sequence, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The same sequence occurs when the chambers deflate, beginning with the chamber closest to the source, and ending with the chamber furthest from the source. The fluid source can either be a fluid supply tube, extending to a supply outside the lumen, or it can be built-in and carried by the device. The device can crawl either along the lumen wall or on an inserted guide wire.

Abstract: A self-propelled device for locomotion through a lumen, comprising a set of serially arranged inflatable chambers, adjacent chambers being fluidly connected, and a fluid source attached to one end of the set, such that the chambers inflate sequentially. The chambers are constructed of an elastic material and have a wall thickness and dimensions such that they have a characteristic with a non-monotonous relationship between the inflation pressure within the chamber and the chamber's inflated size. The characteristic is such that after an initial inflation pressure peak, the non-monotonous relationship adopts a negative slope, such that the volume of the chamber increases more rapidly than the volume of fluid flowing into it, and the inflation pressure of the chamber falls. This effect causes the chamber to inflate and anchor rapidly, while essentially slowing down the inflation of the succeeding chamber until inflation of the first is complete.

Abstract: This application presents methods and devices for continuously cleaning a colon by at least partially filling a segment of the colon with liquid and agitating the fluid to dislodge matter adhering to the colon walls. Methods for automatic maintenance of liquid levels in the colon during continuous cleaning are taught.