Patents by Inventor Noboru Tatsumi

Noboru Tatsumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190175585
    Abstract: The present disclosure provides a patch preparation having features that prevent misuse. In some embodiments, a patch preparation containing a plaster on a support, wherein the plaster comprises a solvent that is a combination of ethyl acetate and n-heptane. The patch preparation can lose its adhesion after the plaster is exposed to air and at least some of the solvent has evaporated, or if the patch is removed from the skin. This feature prevent the used patch from being applied to the skin again, and can prevent misuse. A method of forming a patch preparation is also disclosed.
    Type: Application
    Filed: February 21, 2019
    Publication date: June 13, 2019
    Inventors: Hidetoshi HAMAMOTO, Yasushi MIWA, Katsuhiro YAMANAKA, Noboru TATSUMI
  • Patent number: 10045948
    Abstract: The purpose of the present invention is to provide a nonaqueous tape that is stable and has high percutaneous absorption performance, and that contains pramipexole hydrochloride, which is slightly soluble in organic solvents and has high crystallinity. The present invention could produce a nonaqueous tape that is stable and has high percutaneous absorption performance by dissolving pramipexole, using a combination of a fatty acid ionic liquid and a divalent alcohol and a fatty acid ester. As a result, it has become possible to provide a transdermal patch (tape) containing pramipexole for the treatment of Parkinson's disease with which the problems associated with a conventional water-containing poultice of discoloration of the preparation and stability of the pramipexole can be solved.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: August 14, 2018
    Assignee: MEDRX CO., LTD.
    Inventors: Noboru Tatsumi, Makiko Takemoto, Hidetoshi Hamamoto
  • Publication number: 20170273974
    Abstract: The present disclosure provides a patch preparation having features that prevent misuse. In some embodiments, a patch preparation containing a plaster on a support, wherein the plaster comprises a solvent having a vapor pressure equal to or greater than 1 kPa at 20° C. The patch preparation can lose its adhesion after the plaster is exposed to air and at least some of the solvent has evaporated, or if the patch is removed from the skin. This feature prevent the used patch from being applied to the skin again, and can prevent misuse. A method of forming a patch preparation is also disclosed.
    Type: Application
    Filed: April 24, 2017
    Publication date: September 28, 2017
    Inventors: Hidetoshi HAMAMOTO, Yasushi MIWA, Katsuhiro YAMANAKA, Noboru TATSUMI
  • Publication number: 20170014353
    Abstract: The purpose of the present invention is to provide a nonaqueous tape that is stable and has high percutaneous absorption performance, and that contains pramipexole hydrochloride, which is slightly soluble in organic solvents and has high crystallinity. The present invention could produce a nonaqueous tape that is stable and has high percutaneous absorption performance by dissolving pramipexole, using a combination of a fatty acid ionic liquid and a divalent alcohol and a fatty acid ester. As a result, it has become possible to provide a transdermal patch (tape) containing pramipexole for the treatment of Parkinson's disease with which the problems associated with a conventional water-containing poultice of discoloration of the preparation and stability of the pramipexole can be solved.
    Type: Application
    Filed: February 18, 2015
    Publication date: January 19, 2017
    Applicant: MEDRX CO., LTD.
    Inventors: Noboru Tatsumi, Makiko Takemoto, Hidetoshi Hamamoto
  • Publication number: 20160250336
    Abstract: A Chinese herbal medical composition in the form of jelly, wherein a Chinese herbal medicine is contained in a base containing at least one substance selected from the group consisting of carrageenan, carob bean gum and xanthan gum and not containing phosphate buffer. The Chinese herbal medical composition hardy muses syneresis, is superior in the preservative stability, is broadly applicable to a Chinese herbal medicine and is orally taken without taking care of the bitter of a Chinese herbal medicine.
    Type: Application
    Filed: May 10, 2016
    Publication date: September 1, 2016
    Inventors: Tsunehiro FUKUCHI, Koji MATSUURA, Noboru TATSUMI, Masatake DAIRAKU, Mitsuo TOGASHI
  • Patent number: 9364428
    Abstract: A Chinese herbal medical composition in the form of jelly, wherein a Chinese herbal medicine is contained in a base containing at least one substance selected from the group consisting of carrageenan, carob bean gum and xanthan gum and not containing phosphate buffer. The Chinese herbal medical composition hardly causes syneresis, is superior in the preservative stability, is broadly applicable to a Chinese herbal medicine and is orally taken without taking care of the bitter of a Chinese herbal medicine.
    Type: Grant
    Filed: July 28, 2003
    Date of Patent: June 14, 2016
    Assignee: TEIKOKU SEIYAKU CO., LTD.
    Inventors: Tsunehiro Fukuchi, Koji Matsuura, Noboru Tatsumi, Masatake Dairaku, Mitsuo Togashi
  • Publication number: 20140066471
    Abstract: Disclosed is an external preparation composition having good transdermal absorbability. An external preparation composition having excellent transdermal absorbability can be produced by dissolving a medicinal substance or a salt thereof in a fatty acid-based ionic liquid to form a composite ionic composition of the medicinal substance. The external preparation composition can be used as a liquid preparation, an ointment, a cream, a plaster or the like, and enables to provide a preparation having excellent transdermal absorbability.
    Type: Application
    Filed: November 6, 2013
    Publication date: March 6, 2014
    Applicant: MEDRX CO., LTD.
    Inventors: Toshikazu YAMAGUCHI, Kenta KAWAI, Katsuhiro YAMANAKA, Noboru TATSUMI
  • Patent number: 8623387
    Abstract: Disclosed is an external preparation composition having good transdermal absorbability. An external preparation composition having excellent transdermal absorbability can be produced by dissolving a medicinal substance or a salt thereof in a fatty acid-based ionic liquid to form a composite ionic composition of the medicinal substance. The external preparation composition can be used as a liquid preparation, an ointment, a cream, a plaster or the like, and enables to provide a preparation having excellent transdermal absorbability.
    Type: Grant
    Filed: November 20, 2008
    Date of Patent: January 7, 2014
    Assignee: Medrx Co., Ltd.
    Inventors: Toshikazu Yamaguchi, Kenta Kawai, Katsuhiro Yamanaka, Noboru Tatsumi
  • Publication number: 20110294860
    Abstract: The invention provides a stable and rapidly disintegrable aqueous oral preparation (liquid or jelly preparation) of amlodipine. The liquid preparation comprises an anionic surfactant having a sulfuric acid group or a sulfonic acid group as a stabilizer in an aqueous solution of amlodipine, at pH 5-7, while the jelly preparation further comprises a gelling agent, a fine powder solid, and a gelling regulator.
    Type: Application
    Filed: December 17, 2008
    Publication date: December 1, 2011
    Applicant: MEDRX CO., LTD.
    Inventors: Noboru Tatsumi, Mitsuru Endo, Hidetoshi Hamamoto
  • Publication number: 20100256174
    Abstract: Disclosed is an external preparation composition having good transdermal absorbability. An external preparation composition having excellent transdermal absorbability can be produced by dissolving a medicinal substance or a salt thereof in a fatty acid-based ionic liquid to form a composite ionic composition of the medicinal substance. The external preparation composition can be used as a liquid preparation, an ointment, a cream, a plaster or the like, and enables to provide a preparation having excellent transdermal absorbability.
    Type: Application
    Filed: November 20, 2008
    Publication date: October 7, 2010
    Inventors: Toshikazu Yamaguchi, Kenta Kawai, Katsuhiro Yamanaka, Noboru Tatsumi
  • Patent number: 7678817
    Abstract: An enteric medicinal composition comprising a drug ingredient, pectin, alginic acid, or a derivative thereof, and water is provided that is easy to swallow.
    Type: Grant
    Filed: November 4, 2005
    Date of Patent: March 16, 2010
    Assignee: MEDRX Co., Ltd.
    Inventors: Noboru Tatsumi, Hidetoshi Hamamoto, Masaki Ishibashi, Kanako Shiota, Sueko Matsumura, Keiko Yamasaki
  • Publication number: 20080161364
    Abstract: An object of the present invention is to provide a composition having both of enteric property and dosing property that a conventional composition has not had. The present invention, which can achieve the above object, relates to an enteric medicinal composition, comprising a drug ingredient, pectin, alginic acid or derivative thereof, and water. According to the present invention, it becomes easier to take an enteric composition which has been conventionally difficult to be swallowed.
    Type: Application
    Filed: November 4, 2005
    Publication date: July 3, 2008
    Inventors: Noboru Tatsumi, Hidetoshi Hamamoto, Masaki Ishibashi, Kanako Shiota, Sueko Matsumura, Keiko Yamasaki
  • Publication number: 20070128285
    Abstract: Provided is a pharmaceutical composition for oral administration containing a 5-HT.3 receptor antagonist, which is suitable for self-medication because of good preservation stability, low synthesis, good uniformity and good external appearance, and good smoothness in throat, and easiness to be taken. Concretely, it is a jellied pharmaceutical composition for oral administration containing a 5-HT.3 receptor antagonist, a gelatinizing agent, and water; and having a pH of 7 or less. In particular, there is provided the pharmaceutical composition, where the gelatinizing agent is carrageenan, pectin, agar, alginic acid, sodium alginate, gelatin, manna, Kodak, konjakmannan, glucomannan, chitosan, xanthan gum, tamarind seed polysaccharide, gellan gum, karaya gum, or cassia gum, or preferably the pharmaceutical composition further containing a thickener.
    Type: Application
    Filed: July 12, 2005
    Publication date: June 7, 2007
    Inventors: Chikara Jin, Noboru Tatsumi, Masatake Dairaku, Fuminori Fukushima, Toshio Shimizu, Mitsuo Togashi, Hiroshi Ninomiya
  • Publication number: 20050175628
    Abstract: A Chinese herbal medical composition in the form of jelly, wherein a Chinese herbal medicine is contained in a base containing at least one substance selected from the group consisting of carrageenan, carob bean gum and xanthan gum and not containing phosphate buffer, which hardly causes syneresis, is superior in the preservative stability, especially is broadly applicable to a Chinese herbal medicine and is orally taken without taking care of the bitter of a Chinese herbal medicine.
    Type: Application
    Filed: July 28, 2003
    Publication date: August 11, 2005
    Applicants: TEIKOKU KANPO SEIYAKU CO., LTD, OHATA PHARMACEUTICAL CO., LTD.
    Inventors: Tsunehiro Fukuchi, Koji Matsuura, Noboru Tatsumi, Masatake Dairaku, Mitsuo Togashi