Patents by Inventor Nobuhiro OHKOHCHI

Nobuhiro OHKOHCHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210322513
    Abstract: As a technique for specifically detecting cancer cells, provided is a method for detecting cancer cells, including the steps of: bringing BC2LCN lectin into contact with a test sample; and determining the presence or absence or the amount of a sugar chain having a BC2LCN lectin binding activity in the test sample, in which the test sample is a body fluid sample of a test individual.
    Type: Application
    Filed: June 30, 2021
    Publication date: October 21, 2021
    Inventors: Hiroaki TATENO, Jun HIRABAYASHI, Makoto ASASHIMA, Yuzuru ITOU, Yasuko ONUMA, Tatsuya ODA, Nobuhiro OHKOHCHI, Osamu SHIMOMURA
  • Patent number: 10842585
    Abstract: A model of a body part, e.g., liver, of which the internal structure can be observed easily; and others. In a liver model according to the present invention, the liver parenchyma is formed in the form of a frame to make it possible to observe the portal, veins, a tumor and others in the inside of the frame 31a easily. In addition, the liver model can be handled easily by gripping a gripping part provided at the lower end surface of the inferior vena cava, and the tumor is integrated with the liver model by means of a joint part. The liver model can be manufactured from a model material using a 3D printer on the basis of three-dimensional shape data for model manufacturing purposes, which are produced using an information processing device.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: November 24, 2020
    Assignees: UNIVERSITY OF TSUKUBA, DAI NIPPON PRINTING CO., LTD.
    Inventors: Jun Mitani, Nobuhiro Ohkohchi, Yukio Oshiro, Kentaro Ko, Takuji Hayashi
  • Publication number: 20200037923
    Abstract: The purpose of the present invention is to enable, even in an endoscopic operation, an operation upon a specific operation site while monitoring the overall surgical site, such as an organ. An artificial magnetic field is generated such that a surgical site of a patient is positioned within a generated three-dimensional artificial magnetic field space. A plurality of magnetic sensors are respectively mounted in a plurality of predetermined locations of the surgical site of the patient. Data of a 3-D image of the surgical site and position information of the mounting locations of the magnetic sensors with respect to the surgical site are stored in a storage unit as position information of the mounting locations with respect to the 3-D image of the surgical site.
    Type: Application
    Filed: July 20, 2017
    Publication date: February 6, 2020
    Applicant: University of Tsukuba
    Inventors: Jian LU, Ryutaro MAEDA, Lan ZHANG, Hiroshi HIROSHIMA, Nobuhiro OHKOHCHI, Masanao KURATA, Youichi OKUDA
  • Patent number: 10485874
    Abstract: Hyaluronic acid modified with sphingosine-1-phosphate, and a medicine comprising the hyaluronic acid as an active ingredient, wherein the medicine can alleviate hepatic disorder caused by hypoxia/reoxygenation by protecting the liver sinusoidal endothelial cells, and the medicine can prevent and/or treat liver failure due to liver transplantation, hepatectomy, or other surgeries associated with liver ischemia/reperfusion.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: November 26, 2019
    Assignees: Kewpie Corporation, University of Tsukuba
    Inventors: Hideyoshi Harashima, Mamoru Hyodo, Naoyuki Toriyabe, Nobuhiro Ohkohchi, Takafumi Tamura, Naoki Sano
  • Publication number: 20180250360
    Abstract: As a technique for specifically detecting cancer cells, provided is a method for detecting cancer cells, including the steps of: bringing BC2LCN lectin into contact with a test sample; and determining the presence or absence or the amount of a sugar chain having a BC2LCN lectin binding activity in the test sample, in which the test sample is a body fluid sample of a test individual.
    Type: Application
    Filed: October 5, 2016
    Publication date: September 6, 2018
    Inventors: Hiroaki TATENO, Jun HIRABAYASHI, Makoto ASASHIMA, Yuzuru ITOU, Yasuko ONUMA, Tatsuya ODA, Nobuhiro OHKOHCHI, Osamu SHIMOMURA
  • Publication number: 20180049838
    Abstract: A model of a body part, e.g., liver, of which the internal structure can be observed easily; and others. In a liver model according to the present invention, the liver parenchyma is formed in the form of a frame to make it possible to observe the portal, veins, a tumor and others in the inside of the frame 31a easily. In addition, the liver model can be handled easily by gripping a gripping part provided at the lower end surface of the inferior vena cava, and the tumor is integrated with the liver model by means of a joint part. The liver model can be manufactured from a model material using a 3D printer on the basis of three-dimensional shape data for model manufacturing purposes, which are produced using an information processing device.
    Type: Application
    Filed: February 22, 2016
    Publication date: February 22, 2018
    Applicants: UNIVERSITY OF TSUKUBA, DAI NIPPON PRINTING CO., LTD.
    Inventors: Jun MITANI, Nobuhiro OHKOHCHI, Yukio OSHIRO, Kentaro KO, Takuji HAYASHI
  • Publication number: 20170056509
    Abstract: Hyaluronic acid modified with sphingosine-1-phosphate, and a medicine comprising the hyaluronic acid as an active ingredient, wherein the medicine can alleviate hepatic disorder caused by hypoxia/reoxygenation by protecting the liver sinusoidal endothelial cells, and the medicine can prevent and/or treat liver failure due to liver transplantation, hepatectomy, or other surgeries associated with liver ischemia/reperfusion.
    Type: Application
    Filed: March 5, 2015
    Publication date: March 2, 2017
    Inventors: Hideyoshi HARASHIMA, Mamoru HYODO, Naoyuki TORIYABE, Nobuhiro OHKOHCHI, Takafumi TAMURA, Naoki SANO
  • Publication number: 20150313994
    Abstract: An object of the present invention is to provide surface-modified ferromagnetic iron oxide particles suitable for electromagnetic-induction cancer ablation, which have excellent heat generation properties and also have excellent dispersion stability in a medium for injection. The surface-modified iron oxide particles for cancer ablation of the present invention as a means for achieving the object are characterized in that a block copolymer of polyethylene glycol and polystyrene having a phosphorous acid group in the side chain is bound to the surface of ferromagnetic iron oxide particles having a plate-like shape with a length of 20 to 200 nm and a length-to-thickness ratio of 1.5 to 30 and having magnetic properties such that the coercivity is 30 to 300 Oe, the saturation magnetization is 20 to 80 emu/g, and the squareness ratio of the magnetic hysteresis loop is 0.20 to 0.50.
    Type: Application
    Filed: September 10, 2013
    Publication date: November 5, 2015
    Applicant: UNIVERSITY OF TSUKUBA
    Inventors: Tatsuya ODA, Yukio NAGASAKI, Kei ASAI, Eiji KITA, Hideto YANAGIHARA, Nobuhiro OHKOHCHI, Mikio KISHIMOTO
  • Patent number: 8435734
    Abstract: This invention provides a method for cancer diagnosis comprising measuring an endogenous antisense RNA whose relative expression to a sense RNA changes cancer-specifically in RNA-containing samples collected from a mammal. Also provided are endogenous antisense RNAs useful as cancer markers, and cancer diagnostic reagents containing the same.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: May 7, 2013
    Assignees: Riken, National Institute of Agrobiological Sciences, University of Tsukuba
    Inventors: Hidenori Kiyosawa, Hiroshi Yasue, Nobuhiro Ohkohchi
  • Publication number: 20080299579
    Abstract: This invention provides a method for cancer diagnosis comprising measuring an endogenous antisense RNA whose relative expression to a sense RNA changes cancer-specifically in RNA-containing samples collected from a mammal. Also provided are endogenous antisense RNAs useful as cancer markers, and cancer diagnostic reagents containing the same.
    Type: Application
    Filed: May 30, 2008
    Publication date: December 4, 2008
    Applicants: RIKEN, NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES, UNIVERSITY OF TSUKUBA
    Inventors: Hidenori KIYOSAWA, Hiroshi YASUE, Nobuhiro OHKOHCHI