Patents by Inventor Norbert Schmees

Norbert Schmees has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7659297
    Abstract: The invention relates to multiply-substituted tetrahydronaphthalene derivatives of formula (I) process for their production and their use as antiinflammatory agents.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: February 9, 2010
    Assignee: Bayer Schering Pharma, AG
    Inventors: Hartmut Rehwinkel, Stefan Baeurle, Markus Berger, Norbert Schmees, Heike Schaecke, Konrad Krolikiewicz, Anne Mengel, Duy Nguyen, Stefan Jaroch, Werner Skuballa
  • Patent number: 7638515
    Abstract: The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
    Type: Grant
    Filed: October 12, 2004
    Date of Patent: December 29, 2009
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Hartmut Rehwinkel, Stefan Baeurle, Markus Berger, Norbert Schmees, Heike Schaecke, Konrad Krolikiewicz, Anne Mengel, Duy Nguyen, Stefan Jaroch, Werner Skuballa
  • Publication number: 20090082372
    Abstract: The present invention relates to arylmethylene substituted N-Acyl-?-amino alcohols of the formula I in which Y is selected from the aryl or heteroaryl groups: and R1, R2, R3, R4, R5, Q, X and W have the meaning as defined in the description. The compounds according to the invention are effective FSH antagonists and can be used for example for fertility control in men or in women, or for the prevention and/or treatment of osteoporosis.
    Type: Application
    Filed: July 24, 2008
    Publication date: March 26, 2009
    Inventors: Lars WORTMANN, Marcus Koppitz, Bernd Menzenbach, Dirk Kosemund, Norbert Schmees, Hans-Peter Muhn, Thomas Frenzel, Florian Peter Liesener, Anna Schrey, Ronald Kuehne
  • Patent number: 7442794
    Abstract: The invention relates to the compounds of formula I, a process for their production and their use as anti-inflammatory agents.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: October 28, 2008
    Assignee: Schering AG
    Inventors: Hartmut Rehwinkel, Stefan Baeurle, Markus Berger, Norbert Schmees, Heike Schaecke, Konrad Krolikiewicz, Anne Mengel, Duy Nguyen, Stefan Jaroch, Werner Skuballa
  • Publication number: 20080242866
    Abstract: The present invention relates to a novel method of preparing anthranilamides of formula I: in which R1, R2, R3, A, E, Q, X, and W are defined in the claims, to a novel intermediate compound, and to the use of said novel intermediate compound for the preparation of said anthranilamides of formula I.
    Type: Application
    Filed: March 27, 2008
    Publication date: October 2, 2008
    Inventors: Norbert SCHMEES, Orlin Petrov
  • Patent number: 7417056
    Abstract: Compounds of general formula (IIa) or (IIb) and their use as pharmaceutical agents.
    Type: Grant
    Filed: November 14, 2005
    Date of Patent: August 26, 2008
    Assignee: Schering AG
    Inventors: Stefan Jaroch, Hartmut Rehwinkel, Heike Schaecke, Norbert Schmees, Werner Skuballa, Jan Huebner, Orlin Petrov, Matthias Schneider, Christian Dinter
  • Patent number: 7408060
    Abstract: This invention relates to nonsteroidal progesterone receptor modulators of general formula I, a process for their production, the use of progesterone receptor modulators for the production of pharmaceutical agents as well as pharmaceutical compositions that contain these compounds. The compounds according to the invention are suitable for therapy and prophylaxis of gynecological diseases, such as endometriosis, leiomyomas of the uterus, dysfunctional bleeding and dysmenorrhea, as well as for the therapy and prophylaxis of hormone-dependent tumors and for use for female birth control as well as for hormone replacement therapy.
    Type: Grant
    Filed: June 23, 2006
    Date of Patent: August 5, 2008
    Assignee: Schering AG
    Inventors: Norbert Schmees, Ulrich Bothe, Wolfgang Schwede, Carsten Moeller, Ulrike Fuhrmann, Anja Schmidt
  • Publication number: 20080153859
    Abstract: The invention relates to multiply-substituted tetrahydronaphthalene derivatives of formula (I) process for their production and their use as anti-inflammatory agents.
    Type: Application
    Filed: February 25, 2008
    Publication date: June 26, 2008
    Inventors: Hartmut Rehwinkel, Stefan Baeurle, Markus Berger, Norbert Schmees, Heike Schaecke, Konrad Krolikiewicz, Anne Mengel, Duy Nguyen, Stefan Jaroch, Werner Skuballa
  • Patent number: 7388006
    Abstract: The present invention relates to non-steroidal progestins of the general formula (I) wherein R1 and R2 are independently of each other —H or —F, R3 is —CH3 or —CF3, and Ar is or a pharmaceutically acceptable derivative or analogue thereof. These progestins are suitable for selectively modulating progesterone receptor mediated effects in different target tissues, particularly in uterine tissue versus breast tissue. Therefore, the progestins of the present invention, optionally in combination with estrogens, may be used for contraception (in particular in estrogen-free oral contraceptives), hormone replacement therapy and the treatment of gynecological disorders. The present invention furthermore relates to methods for selectively modulating progesterone receptor mediated effects in different target tissues or organs.
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: June 17, 2008
    Assignee: Bayer Schering Pharma AG
    Inventors: Norbert Schmees, Manfred Lehmann, Ulrike Fuhrmann, Peter Muhn, Christa Hegele-Hartung, Michael Klotzbuecher
  • Patent number: 7378522
    Abstract: The invention relates to new quinoline, isoquinoline and phthalazine derivatives as antagonists of the gonadotropin-releasing hormone.
    Type: Grant
    Filed: July 23, 2004
    Date of Patent: May 27, 2008
    Assignee: Zentaris AG
    Inventors: Peter Strehlke, Peter Droescher, Ulrich Buehmann, Norbert Schmees, Peter Muhn, Holger Hess-Stumpp, Roland Kühne, Eckhard Guenther, Emmanuel Polymeropoulos, Antonius M. Ter Laak
  • Patent number: 7329753
    Abstract: The invention relates to quinoline and isoquinoline derivatives of general formula I and a process for their production, and their use as inflammation inhibitors.
    Type: Grant
    Filed: June 13, 2006
    Date of Patent: February 12, 2008
    Assignee: Schering AG
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Markus Berger, Hartmut Rehwinkel, Konrad Krolikiewicz, Werner Skuballa, Heike Schaecke, Arndt J. G. Schottelius
  • Publication number: 20070225290
    Abstract: The invention relates to multiply substituted tetrahydronaphthalene derivatives of the formula (Ia) to processes for preparing them and to their use as antiinflammatory agents.
    Type: Application
    Filed: March 14, 2007
    Publication date: September 27, 2007
    Inventors: Markus Berger, Hartmut Rehwinkel, Heike Schacke, Stefan Baurle, Norbert Schmees
  • Patent number: 7238707
    Abstract: The invention relates to substituted pentanols, a process for their production and their use as anti-inflammatory agents.
    Type: Grant
    Filed: October 5, 2004
    Date of Patent: July 3, 2007
    Assignee: Schering AG
    Inventors: Stefan Jaroch, Stefan Baeurle, Markus Berger, Konrad Krolikiewicz, Duy Nguyen, Hartmut Rehwinkel, Norbert Schmees, Werner Skuballa, Heike Schaecke
  • Publication number: 20070142464
    Abstract: This invention relates to nonsteroidal progesterone receptor modulators of general formula I, a process for their production, the use of progesterone receptor modulators for the production of pharmaceutical agents as well as pharmaceutical compositions that contain these compounds. The compounds according to the invention are suitable for therapy and prophylaxis of gynecological diseases, such as endometriosis, leiomyomas of the uterus, dysfunctional bleeding and dysmenorrhea, as well as for the therapy and prophylaxis of hormone-dependent tumors and for use for female birth control as well as for hormone replacement therapy.
    Type: Application
    Filed: June 23, 2006
    Publication date: June 21, 2007
    Inventors: Norbert Schmees, Ulrich Bothe, Wolfgang Schwede, Carsten Moeller, Ulrike Fuhrmann, Anja Schmidt
  • Publication number: 20070129358
    Abstract: The invention relates to polysubstituted heterocyclic compounds of the general formula (I) processes for their preparation and their use as anti-inflammatory agents.
    Type: Application
    Filed: May 1, 2006
    Publication date: June 7, 2007
    Inventors: Norbert Schmees, Markus Berger, Hartmut Rehwinkel, Heike Schaecke
  • Patent number: 7166592
    Abstract: Compounds of Formula 1 are useful in the treatment of inflammation.
    Type: Grant
    Filed: June 24, 2004
    Date of Patent: January 23, 2007
    Assignee: Schering Aktiengesellschaft
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Bernd Buchmann, Harmur Rehwinkel, Peter Droescher, Werner Skuballa, Konrad Krolikiewicz, Hartwig Hennekes, Heike Schaecke, Arndr Schottelius
  • Publication number: 20070010514
    Abstract: The present invention relates to non-steroidal progesterone receptor modulators of the general formula I, a process for their preparation, the use of the progesterone receptor modulators for producing medicaments, and pharmaceutical compositions comprising these compounds. The compounds according to the invention are suitable for the therapy and prophylaxis of gynaecological disorders such as endometriosis, leiomyomas of the uterus, dysfunctional bleeding and dysmenorrhoea, and for the therapy and prophylaxis of hormone-dependent tumours and for use for female fertility control and for hormone replacement therapy.
    Type: Application
    Filed: June 23, 2006
    Publication date: January 11, 2007
    Inventors: Ulrich Bothe, Alexander Hillisch, Peter Droescher, Gunter Kaufmann, Lothar Sobek, Ulrike Fuhrmann, Norbert Schmees, Wolfgang Schwede, Carsten Moeller
  • Publication number: 20060293317
    Abstract: The present invention relates to the use of non-steroidal progesterone receptor modulators of the general formula (I) for the therapy and prophylaxis of gynaecological disorders and of hormone-dependent tumours, and for use for female fertility control and for hormone replacement therapy.
    Type: Application
    Filed: June 23, 2006
    Publication date: December 28, 2006
    Inventors: Norbert Schmees, Wolfgang Schwede, Ulrike Fuhrmann, Anja Schmidt, Carsten Moeller
  • Publication number: 20060275800
    Abstract: The invention relates to a process for the characterization of the transactivation and transrepression activity of glucocorticoid receptor (GR) ligands by gene and/or protein expression analysis in primary immune cells as well as the use thereof.
    Type: Application
    Filed: May 1, 2006
    Publication date: December 7, 2006
    Inventors: Wolf Doecke, Christine Rentzsch, Heike Schaecke, Norbert Schmees, Hartmut Rehwinkel, Bettina Schulz, Patrick Golletz, Christine Stock
  • Patent number: 7129270
    Abstract: Compounds of Formula 1 are useful in the treatment of inflammation.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: October 31, 2006
    Assignee: Schėring AG
    Inventors: Stefan JaRoch, Manfred Lehmann, Norbert Schmees, Bernd Buchmann, Harmur Rehwinkel, Peter Droescher, Werner Skuballa, Konrad Krolikiewicz, Hartwig Hennekes, Heike Schaecke, Arndr Schottelius