Patents by Inventor Norikazu Otake

Norikazu Otake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20040204369
    Abstract: This invention relates to compounds which are represented by the general formula [I] 1
    Type: Application
    Filed: May 5, 2004
    Publication date: October 14, 2004
    Inventors: Yufu Sagara, Minaho Uchiyama, Akira Naya, Toshifumi Kimura, Tomoshige Numazawa, Toru Fujikawa, Norikazu Otake, Kazuhito Noguchi
  • Publication number: 20040147506
    Abstract: This invention relates to benzimidazolone derivatives, represented by compounds of a general formula [I] 1
    Type: Application
    Filed: October 20, 2003
    Publication date: July 29, 2004
    Inventors: Takeru Yamakawa, Yoshio Ogino, Yufu Sagara, Kenji Matsuda, Akira Naya, Toshifumi Kimura, Norikazu Otake
  • Publication number: 20040054177
    Abstract: The present invention relates to a compound of the formula (I): 1
    Type: Application
    Filed: June 18, 2003
    Publication date: March 18, 2004
    Inventors: Norikazu Otake, Minoru Moriya, Yoshio Ogino, Kenji Matsuda, Yoshikazu Nagae, Akio Kanatani, Takehiro Fukami
  • Patent number: 6699880
    Abstract: This invention relates to the compounds represented by the general formula [I], [in which A—D signify optionally substituted methine group(s) or nitrogen atom; E signifies oxygen or sulfur atom; signify optionally substituted mono- or bi-cyclic aliphatic nitrogen-containing heterocyclic group(s); R1 signifies lower alkenyl, lower alkynyl, cyclo(lower alkyl), lower alkanoyl, lower alkoxycarbonyl, optionally substituted lower alkyl and the like; and R2 signifies lower alkyl].
    Type: Grant
    Filed: April 15, 2002
    Date of Patent: March 2, 2004
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Takeru Yamakawa, Makoto Ando, Seita Koito, Kenji Ohwaki, Toshifumi Kimura, Toshihiko Saeki, Mitsuru Miyaji, Yuki Iwahori, Toru Fujikawa, Norikazu Otake, Kazuhito Noguchi
  • Publication number: 20030191316
    Abstract: This invention relates to compounds which exhibit selective muscarinic M3 receptor antagonism, have little side effects, are suitable for inhalation therapy and are useful as treating agents of respiratory system diseases, of the general formula (I); 1
    Type: Application
    Filed: January 10, 2003
    Publication date: October 9, 2003
    Inventors: Yoshio Ogino, Hideki Kurihara, Kenji Matsuda, Tomoshige Numazawa, Norikazu Otake, Kazuhito Noguchi
  • Patent number: 6413979
    Abstract: The present invention relates to a cyclopentenopyridine derivative represented by general formula (I) or a pharmaceutically acceptable salt thereof, wherein Ar is a phenyl group or the like. R1 is a mono- or di-C1-C6 alkylamino group or the like, and R2 is a hydroxyl group or the like, a process for its production and its use.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: July 2, 2002
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Takashi Hayama, Norikazu Otake, Masaru Nishikibe
  • Patent number: 6251891
    Abstract: A compound represented by the general formula wherein R1 either represents a hydrogen atom or a lower alkyl group, R2 represents a hydrogen atom, an ester residue, an alkali metal or negative charge, and R3 and R4 are the same or different, and each represent a hydrogen atom or a hydrocarbonic group optionally containing hetero atom(s) selected from the group consisting of oxygen atom(s), sulfur atom(s) and nitrogen atom(s), or they are combined together with the nitrogen atom to which they bound to form a heterocyclic group, and the use thereof as an antibacterial agent.
    Type: Grant
    Filed: April 19, 1999
    Date of Patent: June 26, 2001
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Susumu Nakagawa, Norikazu Otake, Hideo Kiyonaga, Koji Yamada, Hideki Jona, Shigemitsu Okada, Masayuki Ogawa, Hideaki Imamura, Ryosuke Ushijima
  • Patent number: 5225406
    Abstract: The present invention relates to a compound having the formula: ##STR1## wherein R is a hydrogen atom, a carboxyl-protecting group or a negative charge and Q is a hydrogen atom, a halogen atom, a hydroxyl group, an acetoxy group, a carbamoyloxy group, an azide group, a substituted or unsubstituted quarternary ammonio group or a substituted or unsubstituted heterocyclic thio group having at least one hetero atom selected from the group consisting of a nitrogen atom, an oxygen atom, and a sulfur atom, or a non-toxic salt or physiologically hydrolyzable non-toxic ester thereof; a process for producing it; and an antibacterial agent comprising it as an active ingredient.Further, the present invention also relates to a compound having the formula: ##STR2## wherein R.sup.3 is a hydrogen atom or an amino-protecting group, and each of R.sup.4 and R.sup.5 which may be the same or different is a hydrogen atom or a carboxyl-protecting group, or a salt thereof; and a process for producing it.
    Type: Grant
    Filed: September 3, 1991
    Date of Patent: July 6, 1993
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Susumu Nakagawa, Ryuji Mitomo, Koji Yamada, Norikazu Otake, Fumio Nakano, Akira Asai, Satoru Kuroyanagi, Yoshiharu Tanaka, Moriaki Ishikawa, Ryosuke Ushijima
  • Patent number: 5095013
    Abstract: A compound of the formula: ##STR1## wherein R.sup.1 is a hydrogen atom or a methyl group, R.sup.2 is a hydrogen atom or a lower alkyl group, each of R.sup.3, R.sup.4 and R.sup.5 is a hydrogen atom or a lower alkyl group, or R.sup.3 and R.sup.4 together form a methylene group, an ethylene group or a propylene group, or R.sup.4 and R.sup.5 form together with the adjacent nitrogen atom an aziridinyl group, an azetidinyl group, a pyrrolidinyl group, a piperidino group, a piperazinyl group or a morpholino group; or a pharmaceutically acceptable salt or ester thereof.
    Type: Grant
    Filed: August 3, 1990
    Date of Patent: March 10, 1992
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Susumu Nakagawa, Fumio Nakano, Norikazu Otake, Ryosuke Ushijima
  • Patent number: 5084453
    Abstract: The present invention relates to a compound having the formula: ##STR1## wherein R is a hydrogen atom, a carboxyl-protecting group or a negative charge and Q is a hydrogen atom, a halogen atom, a hydroxyl group, an acetoxy group, a carbamoyl group, an azide group, a substituted or unsubstituted quarternary ammonio group or a substituted or unsubstituted heterocyclic thio group having at least one hetero atom selected from the group consisting of a nitrogen atom, an oxygen atom and a sulfur atom, or a non-toxic salt or physiologically hydrolyzable non-toxic ester thereof; a process for producing it; and an antibacterial agent comprising it as an active ingredient.Further, the present invention also relates to a compound having the formula: ##STR2## wherein R.sup.3 is a hydrogen atom or an amino-protecting group, and each of R.sup.4 and R.sup.5 which may be the same or different is a hydrogen atom or a carboxyl-protecting group, or a salt thereof; and a process for producing it.
    Type: Grant
    Filed: October 13, 1988
    Date of Patent: January 28, 1992
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Susumu Nakagawa, Ryuji Mitomo, Koji Yamada, Norikazu Otake, Fumio Nakano, Akira Asai, Satoru Kuroyanagi, Yoshiharu Tanaka, Moriaki Ishikawa, Ryosuke Ushijima
  • Patent number: 5061794
    Abstract: A compound having the formula: ##STR1## wherein R is a straight chain or branched chain lower alkyl, cyclic lower alkyl, lower alkenyl (except for 1-carboxy-1-vinyl), lower alkynyl, aralkyl, phenyl or 2-pyrrolidon-3-yl group which may be substituted, and Q is ##STR2## (wherein R.sup.1 is a hydrogen atom or an acetyl group, R.sup.2 is a hydrogen atom, a carboxyl group or a carboxymethyl group, Y is a sulfur atom or an oxygen atom, Z is a sulfur atom, an oxygen atom or an imino group which may be substituted by a lower alkyl group); or a pharmaceutically acceptable salt, physiologically hydrolyzable ester or solvate thereof.
    Type: Grant
    Filed: July 10, 1989
    Date of Patent: October 29, 1991
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Susumu Nakagawa, Koji Yamada, Fumio Nakano, Norikazu Otake, Akira Asai, Satoru Kuroyanagi, Yoshiharu Tanaka, Moriaki Ishikawa, Ryosuke Ushijima, Ryuji Mitomo
  • Patent number: 4814328
    Abstract: The compound having the formula: ##STR1## wherein R is a straight chain, branched chain or cyclic lower alkyl, a lower alkenyl or a lower alkynyl group which may be substituted by a carboxyl group, and R.sup.1 is hydrogen atom or an acetyl group; or a pharmaceutically acceptable salt, physiologically hydrolyzable ester or solvate thereof.
    Type: Grant
    Filed: September 26, 1986
    Date of Patent: March 21, 1989
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Susumu Nakagawa, Norikazu Otake, Ryosuke Ushizima
  • Patent number: 4782155
    Abstract: The compound having the formula: ##STR1## wherein R.sup.6 is a hydrogen atom or an alkanoyl group, or a salt thereof and a process thereof.
    Type: Grant
    Filed: March 25, 1987
    Date of Patent: November 1, 1988
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Susumu Nakagawa, Norikazu Otake, Ryosuke Ushijima