Patents by Inventor Norman Purvis

Norman Purvis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170350911
    Abstract: The invention provides systems, compositions, kits and methods for automated processing of biological samples and analysis using a flow cytometer.
    Type: Application
    Filed: June 22, 2017
    Publication date: December 7, 2017
    Inventors: Todd M. COVEY, Adam PALAZZO, Norman PURVIS, James CORDIERO, David ROSEN
  • Publication number: 20170212136
    Abstract: A method is disclosed in which control processes are used to maintain consistency across a research or diagnostic series of steps. Some embodiments of the processes include the use of fresh or lyophilized cell lines, beads, surface or other markers. The use of quality control processes is intended to monitor data from the underlying methods in order to detect unacceptable variations and to allow for exclusion or normalization. Overlapping control processes allows for tighter control and for redundancy in the monitoring.
    Type: Application
    Filed: August 1, 2016
    Publication date: July 27, 2017
    Inventors: Norman Purvis, Santosh Putta, Matt Westfall, David Rosen, David Spellmeyer, Jason Ptacek
  • Patent number: 9183237
    Abstract: In one embodiment, one or more processor-readable media storing code representing instructions that when executed by one or more processors cause the one or more processors to receive a set of parameter values defining a boundary within a data space associated with a dataset. The dataset can represent signaling related to a test substance. A first metric can be defined based on a first portion of the dataset associated with a first region defined by the boundary. A second metric can be defined based on a second portion of the dataset associated with a second region defined by the boundary after the boundary is modified. The second region can be different than the first region.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: November 10, 2015
    Inventors: Steven C. Banville, Santosh K. Putta, David C. Spellmeyer, Nikil Wale, Erik Evensen, Norman Purvis, Greg Friedland
  • Publication number: 20150309062
    Abstract: The invention provides systems, compositions, kits and methods for automated processing of biological samples and analysis using a flow cytometer.
    Type: Application
    Filed: March 24, 2015
    Publication date: October 29, 2015
    Inventors: Todd M. Covey, Adam Palazzo, Norman Purvis, James Cordiero, David Rosen
  • Patent number: 9034257
    Abstract: The invention provides systems, compositions, kits and methods for automated processing of biological samples and analysis using a flow cytometer.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: May 19, 2015
    Assignee: Nodality, Inc.
    Inventors: Todd Covey, Adam Palazzo, Norman Purvis, James Cordiero, David Rosen
  • Publication number: 20130035253
    Abstract: The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations.
    Type: Application
    Filed: August 3, 2012
    Publication date: February 7, 2013
    Applicant: Nodality, Inc. A Delaware Corporation
    Inventors: David B. Rosen, Santosh K. Putta, Brent Louie, Norman Purvis
  • Publication number: 20100105074
    Abstract: The invention provides systems, compositions, kits and methods for automated processing of biological samples and analysis using a flow cytometer.
    Type: Application
    Filed: October 27, 2009
    Publication date: April 29, 2010
    Applicant: Nodality, Inc. a Delaware Corporation
    Inventors: Todd Covey, Adam Palazzo, Norman Purvis, James Cordiero, David Rosen
  • Publication number: 20080096231
    Abstract: Whole cell, simultaneous target and drug-target assay using differentially labeled antibodies and flow cytometry. First antibody binds to total target and second antibody binds to the drug binding site of the target, thus drug binding will competitively inhibit the second antibody allowing for a competitive inhibition assay of drug-target binding. The assay allows for whole cell analysis and even analysis of mixed populations of cells, yet provides detailed kinetic assessment of drug activity.
    Type: Application
    Filed: October 29, 2007
    Publication date: April 24, 2008
    Applicant: Esoterix, Inc.
    Inventors: Norman Purvis, Gregory Stelzer
  • Publication number: 20050266503
    Abstract: Whole cell, simultaneous target and drug-target assay using differentially labeled antibodies and flow cytometry. First antibody binds to total target and second antibody binds to the drug binding site of the target, thus drug binding will competitively inhibit the second antibody allowing for a competitive inhibition assay of drug-target binding. The assay allows for whole cell analysis and even analysis of mixed populations of cells, yet provides detailed kinetic assessment of drug activity.
    Type: Application
    Filed: May 24, 2005
    Publication date: December 1, 2005
    Applicant: Esoterix, Inc.
    Inventors: Norman Purvis, Gregory Stelzer