Patents by Inventor Ofer Levy

Ofer Levy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140220011
    Abstract: This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against VSIG1, ILDR1, LOC253012, AI216611, ClORF32 or FXYD3 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages. The use of these antibodies for modulating B7 costimulation and related therapies such as the treatment of autoimmunity are also provided. This invention further relates to the discovery of extracellular domains of VSIG1 and its variants, FXYD3 and its variants, ILDR1 and its variants, LOC253012 and its variants, AI216611 and its variants, and ClORF32 and its variants which are suitable targets for immunotherapy, cancer therapy, and drug development.
    Type: Application
    Filed: February 15, 2013
    Publication date: August 7, 2014
    Applicant: COMPUGEN LTD.
    Inventors: Amir TOPORIK, Amit NOVIK, Anat COHEN-DAYAG, Avi Yeshah ROSENBERG, Cynthia KOIFMAN, Dalit LANDESMAN-MILO, Eve MONTIA, Galit ROTMAN, Liat DASSA, Marina BUBIS, Merav BEIMAN, Ofer LEVY, Sergey NEMZER, Tania PERGAM, Yaron KINAR, Shirley SAMEACH-GREENWALD, Zurit LEVINE, Shira WALACH
  • Publication number: 20140189328
    Abstract: A computer processor, a computer system and a corresponding method involve a reservation station that stores instructions which are not ready for execution. The reservation station includes a storage area that is divided into bundles of entries. Each bundle is switchable between an open state in which instructions can be written into the bundle and a closed state in which instructions cannot be written into the bundle. A controller selects which bundles are open based on occupancy levels of the bundles.
    Type: Application
    Filed: December 27, 2012
    Publication date: July 3, 2014
    Inventors: Tomer WEINER, Zeev SPERBER, Sagi LAHAV, Guy PATKIN, Gavri BERGER, Itamar FELDMAN, Ofer LEVY, Sara YAKOEL, Adi YOAZ
  • Publication number: 20140189314
    Abstract: A method of an aspect includes generating real time instruction trace (RTIT) packets for a first logical processor of a processor. The RTIT packets indicate a flow of software executed by the first logical processor. The RTIT packets are stored in an RTIT queue corresponding to the first logical processor. The RTIT packets are transferred from the RTIT queue to memory predominantly with firmware of the processor. Other methods, apparatus, and systems are also disclosed.
    Type: Application
    Filed: December 29, 2012
    Publication date: July 3, 2014
    Inventors: Tsvika Kurts, Ofer Levy, Itamar Kazachinsky, Gabi Malka, Zeev Sperber, Jason W. Brandt
  • Publication number: 20140142024
    Abstract: Described herein is a method of mitigating, in a subject (individual), tissue injury resulting from exposure to radiation (accidental/unintentional or intentional, such as therapeutic), chemoradiotherapy, disease, toxin, or drug or biologic mediated therapy.
    Type: Application
    Filed: April 5, 2012
    Publication date: May 22, 2014
    Applicants: Children's Medical Center Corporation, Dana-Farber Cancer Institute, Inc.
    Inventors: Eva Guinan, Ofer Levy
  • Publication number: 20140056811
    Abstract: The present invention is related to peptides, which are suitable for use as cell-penetrating peptides (CPPs), variants thereof and/or complexes, fusion molecules and/or conjugates comprising same, use thereof for manufacture of compositions for diagnosing, treating and/or preventing of medical conditions.
    Type: Application
    Filed: December 26, 2011
    Publication date: February 27, 2014
    Applicant: COMPUGEN LTD.
    Inventors: Etai Jacob, Amir Toporik, Ronen Shemesh, Ofer Levy
  • Publication number: 20140037549
    Abstract: The present invention discloses markers useful in predicting the responsiveness of a subject having, or at risk of developing rheumatoid arthritis (RA) to treatment with anti-TNF agents. Particularly, the present invention discloses the allelic configuration of the CD6 gene and/or the STXBP6 gene which is indicative of the degree of responsiveness to anti-TNF? treatment of RA.
    Type: Application
    Filed: February 12, 2012
    Publication date: February 6, 2014
    Applicant: COMPUGEN LTD.
    Inventors: Akiva Pinchas, Sarit Edelheit-Flohr, Lily Bazak, Zurit Levine, Amir Toporik, Ofer Levy, Tomer Zekharya, Assaf Wool
  • Publication number: 20140013091
    Abstract: Some implementations provide techniques and arrangements for causing an interrupt in a processor in response to an occurrence of a number of events. A first event counter counts the occurrences of a type of event within the processor and outputs a signal to activate a second event counter in response to reaching a first predefined count. The second event counter counts the occurrences of the type of event within the processor and causes an interrupt of the processor in response to reaching a second predefined count.
    Type: Application
    Filed: December 29, 2011
    Publication date: January 9, 2014
    Inventors: Ahmad Yasin, Peggy J. Irelan, Ofer Levy, Emile Ziedan, Grant Zhou
  • Publication number: 20140004175
    Abstract: Provided are angiopoietin-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Application
    Filed: June 18, 2013
    Publication date: January 2, 2014
    Applicant: Compugen Ltd.
    Inventors: Yossef KLIGER, Itamar Borukhov, Ofer Levy, Zohar Tiran, Assaf Wool, Ehud Schreiber, Anat Amir, Zurit Levine, Amir Toporik
  • Publication number: 20130315819
    Abstract: This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against KIAA0746, CD20 or CD55 antigens, which are differentially expressed in cancer and in specific blood cells, and diagnostic and therapeutic usages. This invention further relates to the discovery of extracellular domains of KIAA0746 and its variants, CD20 and its variants, CD55 and its variants, which are suitable targets for immunotherapy, cancer therapy, treatment of inflammatory, allergic and autoimmune disorders, and drug development.
    Type: Application
    Filed: May 29, 2013
    Publication date: November 28, 2013
    Applicant: COMPUGEN LTD.
    Inventors: Amir TOPORIK, Anat COHEN-DAYAG, Avi Yeshah ROSENBERG, Eve MONTIA, Galit ROTMAN, Liat DASSA, Meirav BEIMAN, Ofer LEVY, Sergey NEMZER, Shira WALACH, Shirley SAMEACH- GREENWALD, Yaron KINAR, Zurit LEVINE
  • Patent number: 8575107
    Abstract: Clusterin-derived peptides or homologues or derivatives thereof, pharmaceutical compositions including the same, methods of manufacturing the peptides, homologues, derivatives thereof and compositions including the same, and methods of treating conditions including administering the peptides, homologues, derivatives thereof and compositions including the same, are provided. Also provided are nucleotide sequences encoding the peptides, homologues, derivatives thereof and compositions including the same, antibodies directed to epitopes thereof and fusion proteins including the same.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: November 5, 2013
    Assignee: Compugen Ltd.
    Inventors: Yossef Kliger, Ofer Levy, Itamar Borukhov, Assaf Wool, Ehud Schreiber, Anat Amir, Zurit Levine, Zohar Tiran, Anat Oren, Amir Toporik
  • Publication number: 20130262926
    Abstract: An error recovery unit that may include error logic to detect an error in a dispatch port and timestamp logic configured to generate a timestamp for the error. The error recovery unit may also include check logic to determine if an instruction associated with the error has been retired based on the timestamp. If the instruction has been retired, a machine check error logic may be initiated. If the instruction has not been retired, an error correction logic may be initiated to recover the error and to re-execute the instruction. Thus, speculative errors may be recovered without the need for calling the machine check error, which is undesirable because of its catastrophic nature. Therefore, machine check errors may be significantly reduced.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 3, 2013
    Applicant: INTEL CORPORATION
    Inventors: Zeev SPERBER, Ofer LEVY, Michael MISHAELI, Ron GABOR
  • Patent number: 8529943
    Abstract: Provided are angiopoietin-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Grant
    Filed: July 20, 2009
    Date of Patent: September 10, 2013
    Assignee: Compugen Ltd.
    Inventors: Yossef Kliger, Itamar Borukhov, Ofer Levy, Zohar Tiran, Assaf Wool, Ehud Schreiber, Anat Amir, Zurit Levine, Amir Toporik
  • Patent number: 8512708
    Abstract: Provided is a gp96-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Grant
    Filed: March 12, 2009
    Date of Patent: August 20, 2013
    Assignee: Compugen Ltd.
    Inventors: Yossef Kliger, Ofer Levy, Itamar Borukhov, Anat Amir, Anat Oren
  • Publication number: 20130113559
    Abstract: A method and a device may be provided.
    Type: Application
    Filed: January 25, 2012
    Publication date: May 9, 2013
    Applicant: VYYCORE LTD.
    Inventors: Doron KOREN, Sergey TOUJIKOV, Ofer LEVY
  • Patent number: 8415455
    Abstract: This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against VSIG1, ILDR1, LOC253012, AI216611, C1ORF32 or FXYD3 antigens, which are predicted co-stimulatory family members and which are differentially expressed in cancers including, lung cancer, ovarian cancer, and colon cancer, and diagnostic and therapeutic usages. The use of these antibodies for modulating B7 costimulation and related therapies such as the treatment of autoimmunity are also provided. This invention further relates to the discovery of extracellular domains of VSIG1 and its variants, FXYD3 and its variants, ILDR1 and its variants, LOC253012 and its variants, AI216611 and its variants, and C1ORF32 and its variants which are suitable targets for immunotherapy, cancer therapy, and drug development.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: April 9, 2013
    Assignee: Compugen Ltd
    Inventors: Zurit Levine, Tania Pergam, Dalit Landesman-Milo, Anat Cohen-Dayag, Amir Toporik, Yaron Kinar, Sergey Nemzer, Avi Rosenberg, Galit Rotman, Amit Novik, Cynthia Koifman, Merav Beiman, Liat Dassa, Shira Walach, Eve Montia, Shirley Sameach-Greenwald, Ofer Levy, Marina Bubis
  • Publication number: 20130044836
    Abstract: A method and a device. The device may include: a non-linear amplifying circuit for applying a non-linear gain function on an analog signal to provide an amplified signal; an input circuit, for clipping I-channel and Q-channel digital input signals, to provide clipped I-channel and Q-channel digital signals; a pre-distortion circuit, for pre-distorting the clipped I-channel and Q-channel digital signals such as to at least partially compensate for a non-linearity of the non-linear gain function, to provide pre-distorted I-channel and Q-channel digital signals; a mixed signal circuit for converting the pre-distorted I-channel and Q-channel digital signals to the analog signal; a reconstruction circuit for generating reconstructed I-channel and Q-channel signals; and a control circuit, arranged to: calculate an error attribute based on the clipped and the reconstructed I-channel and Q-channel digital signals and to affect a gain of at least one components of the device in response to the error attribute.
    Type: Application
    Filed: August 18, 2011
    Publication date: February 21, 2013
    Applicant: VYYCORE LTD.
    Inventors: DORON KOREN, SERGEY TOUJIKOV, Ofer Levy
  • Publication number: 20120238460
    Abstract: Disclosed herein are methods for determining the likelihood of a subject to develop Acute graft versus host disease (aGVHD) upon receiving myeloablative allogeneic hematopoietic stem cell transplantation (HSCT). One such method comprises assaying for baseline plasma concentration of RANTES in a sample obtained from the subject, and comparing the baseline plasma concentration of RANTES to a predetermined level. The method may further comprise assaying for day 7 plasma concentration of RANTES in sample obtained from the subject, and comparing the day 7 plasma concentration of RANTES to a predetermined level. Another such method comprises assaying for day 7 plasma concentration of RANTES in a sample obtained from the subject, and comparing the day 7 plasma concentration of RANTES to a predetermined level.
    Type: Application
    Filed: November 10, 2008
    Publication date: September 20, 2012
    Applicants: DANA-FARBER CANCER INSTITUTE, INC., CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Ofer Levy, Eva Guinan, Eugenie Suter
  • Publication number: 20120128715
    Abstract: The present invention is based on the surprising discovery that agonists of TLR8 are uniquely efficacious in enhancing (e.g. inducing) the immune response of newborns. Thus, agonists of TLR8 serve as both vaccine adjuvants and as adjunctive therapies for acute infection in newborns, preferably the agonist is a TLR8-selective agonist. The immune response induced, or enhanced, in the neonatal host can be, for example, a cytokine immune response and/or a humoral immune response (e.g., antigen-specific).
    Type: Application
    Filed: January 20, 2012
    Publication date: May 24, 2012
    Applicants: 3M INNOVATIVE PROPERTIES COMPANY, CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Ofer Levy, Michael Wessels, Richard Miller, Mark Tomai
  • Publication number: 20110311450
    Abstract: This invention relates to a novel target for production of immune and non-immune based therapeutics and for disease diagnosis. More particularly, the invention provides therapeutic antibodies against KRTCAP3, FAM26F, MGC52498, FAM70A or TMEM154 antigens, which are differentially expressed in cancer, and diagnostic and therapeutic usages. This invention further relates to extracellular domains of KRTCAP3, FAM26F, MGC52498, FAM70A and TMEM154 proteins and variants, and therapeutic usages thereof.
    Type: Application
    Filed: December 8, 2009
    Publication date: December 22, 2011
    Inventors: Zurit Levine, Avi Rosenberg, Galit Rotman, Amit Novik, Amir Toporik, Yaron Kinar, Sergey Nemzer, Shira Walach, Eve Montia, Shirley Sameach-Greenwald, Liat Dassa, Merav Beiman, Anat Cohen-Dayag, Ofer Levy
  • Publication number: 20110206760
    Abstract: Provided are angiopoietin-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
    Type: Application
    Filed: July 20, 2009
    Publication date: August 25, 2011
    Applicant: COMPUGEN LTD.
    Inventors: Yossef Kliger, Itamar Borukhov, Ofer Levy, Zohar Tiran, Assaf Wool, Ehud Schreiber, Anat Amir, Zurit Levine, Amir Toporik