Patents by Inventor Oh-Young Yeo

Oh-Young Yeo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Injectable anticancer composition for local administration containing suspension of quinine salt
    Patent number: 10441582
    Abstract: Disclosed herein is an injectable anticancer composition for local administration, which contains a suspension of quinine hydrochloride. The anticancer composition for local administration according to the present invention shows an IC50 value against MKN-45 cells, which is about 10 times lower than Paclitaxel, as determined by an MTT assay in vitro, suggesting that the anticancer composition has an excellent cytotoxic effect. The anticancer composition can be administered as a safe anticancer agent in clinical applications, and also shows an anticancer effect by inducing the necrosis and detachment of solid cancer cells. Particularly, the anticancer composition has an anticancer mechanism by which the composition acts locally in a tumor tissue administered with the composition and shows a rapid antitumor effect (1-2 weeks after administration).
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: October 15, 2019
    Inventor: Oh Young Yeo
  • INJECTABLE ANTICANCER COMPOSITION FOR LOCAL ADMINISTRATION CONTAINING SUSPENSION OF QUININE SALT
    Publication number: 20170360769
    Abstract: Disclosed herein is an injectable anticancer composition for local administration, which contains a suspension of quinine hydrochloride. The anticancer composition for local administration according to the present invention shows an IC50 value against MKN-45 cells, which is about 10 times lower than Paclitaxel, as determined by an MTT assay in vitro, suggesting that the anticancer composition has an excellent cytotoxic effect. The anticancer composition can be administered as a safe anticancer agent in clinical applications, and also shows an anticancer effect by inducing the necrosis and detachment of solid cancer cells. Particularly, the anticancer composition has an anticancer mechanism by which the composition acts locally in a tumor tissue administered with the composition and shows a rapid antitumor effect (1-2 weeks after administration).
    Type: Application
    Filed: April 26, 2017
    Publication date: December 21, 2017
    Inventor: OH YOUNG YEO
  • Injectable composition containing hydroxychloroquine for local administration for treating hemorrhoids
    Patent number: 8871228
    Abstract: The present invention relates to an injectable composition for local administration for treating hemorrhoids, which contains hydroxychloroquine. Specifically, the composition contains a solution of hydroxychloroquine in physiological saline for injection, together with a local anesthetic and an antioxidant.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: October 28, 2014
    Inventor: Oh-Young Yeo
  • Injectable anticancer composition for local administration containing hydroxychloroquine
    Patent number: 8506973
    Abstract: The present invention relates to an injectable anticancer composition for local administration comprising hydroxychloroquine. The anticancer composition shows an IC50 value against sarcoma-180 cells, which is about 10 times lower than cisplatin, as determined by the MTT assay in vitro, suggesting that the anticancer composition has an excellent cytotoxic effect. Also, the anticancer composition shows dose-dependent effects against solid cancer induced by sarcoma-80 cells in vivo. In addition, the anticancer composition has the effect of extending the life expectancy of patients having ascites cancer induced by sarcoma-80 cells.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: August 13, 2013
    Inventor: Oh-Young Yeo
  • INJECTABLE COMPOSITION CONTAINING HYDROXYCHLOROQUINE FOR LOCAL ADMINISTRATION FOR TREATING HEMORRHOIDS
    Publication number: 20120108633
    Abstract: The present invention relates to an injectable composition for local administration for treating hemorrhoids, which contains hydroxychloroquine. Specifically, the composition contains a solution of hydroxychloroquine in physiological saline for injection, together with a local anesthetic and an antioxidant.
    Type: Application
    Filed: June 18, 2010
    Publication date: May 3, 2012
    Inventor: Oh-Young Yeo
  • INJECTABLE ANTICANCER COMPOSITION FOR LOCAL ADMINISTRATION CONTAINING HYDROXYCHLOROQUINE
    Publication number: 20120095045
    Abstract: The present invention relates to an injectable anticancer composition for local administration comprising hydroxychloroquine. The anticancer composition shows an IC50 value against sarcoma-180 cells, which is about 10 times lower than cisplatin, as determined by the MTT assay in vitro, suggesting that the anticancer composition has an excellent cytotoxic effect. Also, the anticancer composition shows dose-dependent effects against solid cancer induced by sarcoma-80 cells in vivo. In addition, the anticancer composition has the effect of extending the life expectancy of patients having ascites cancer induced by sarcoma-80 cells.
    Type: Application
    Filed: June 18, 2010
    Publication date: April 19, 2012
    Inventor: Oh-Young Yeo