Patents by Inventor Oliver Hartley

Oliver Hartley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220302710
    Abstract: A power distribution apparatus, comprising: a plurality of switches each operable to switch a respective power source of a plurality of power sources between a first input node of a first load and a second input node of a second load; a first power meter configured to determine a first power being delivered to the first input node from the plurality of power sources via the plurality of switches; a second power meter configured to determine the power consumption of the first load; and a control module configured to control the switches to distribute power between the first and second loads in dependence on the determined first power and the determined power consumption of the first load.
    Type: Application
    Filed: September 4, 2020
    Publication date: September 22, 2022
    Inventors: Oliver Hartley, Luke Butterworth, Matthias Huchel, Jose Roberto Moreira Rodrigues, Musa Chibowora, Jean-Louis Francisco De Geronimo Salinas
  • Publication number: 20210340173
    Abstract: The present application relates to methods for producing structurally variant polypeptide molecules in parallel using column-free techniques by polypeptide ligation, separation of ligated polypeptides from ligation reactions, folding of polypeptides, and desalting of polypeptides. Further described are methods for determining the effects and properties of structurally variant polypeptide molecules produced in parallel using column-free techniques.
    Type: Application
    Filed: September 25, 2019
    Publication date: November 4, 2021
    Applicant: UNIVERSITÉ DE GENÈVE
    Inventors: Oliver Hartley, Marianne Paolini-Bertrand
  • Publication number: 20210205412
    Abstract: The present invention provides methods of inhibiting cerebral inflammation comprising administering a CCR5 inhibitor to a subject.
    Type: Application
    Filed: May 24, 2019
    Publication date: July 8, 2021
    Applicants: UNIVERSITÉ DE GENÈVE, ORION BIOTECHNOLOGY SWITZERLAND SÀRL, HÔPITAUX UNIVERSITAIRES DE GENÈVE
    Inventors: Doron Merkler, Karin Elke Steinbach, Oliver Hartley
  • Publication number: 20210205411
    Abstract: The present invention provides methods of treating cancer comprising administering a CCR5 inhibitor to a subject.
    Type: Application
    Filed: May 24, 2019
    Publication date: July 8, 2021
    Applicant: ORION BIOTECHNOLOGY SWITZERLAND SÀRL
    Inventors: Oliver Hartley, Robin Ewart Offord
  • Patent number: 10689461
    Abstract: Provided herein are display systems for simultaneously displaying two different ligand binding polypeptides at the surface of a phage. Also provided are kits, methods of using such display systems and methods of discovering novel bispecific antibodies.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: June 23, 2020
    Assignee: NovImmune SA
    Inventors: Séverine Fagète, Oliver Hartley, Nicolas Fischer
  • Patent number: 10087234
    Abstract: The invention relates to mimetic peptides of epitope(s) of Apolipoprotein A-I, diagnostic immunoassays comprising such mimetic peptides, as well as methods for diagnosing and methods for preventing and/or treating a cardiovascular disease.
    Type: Grant
    Filed: November 6, 2013
    Date of Patent: October 2, 2018
    Assignees: LES HOPITAUX UNIVERSITAIRES DE GENEVE, UNIVERSITE DE GENEVE, HOFFMAN-LA ROCHE INC.
    Inventors: Nicolas Vuilleumier, Sabrina Pagano, Oliver Hartley, Hubert Gaertner, Priscila Camillo Teixeira, Paul Cutler, Philippe Ferber
  • Publication number: 20180134809
    Abstract: Provided herein are display systems for simultaneously displaying two different ligand binding polypeptides at the surface of a phage. Also provided are kits, methods of using such display systems and methods of discovering novel bispecific antibodies.
    Type: Application
    Filed: September 15, 2017
    Publication date: May 17, 2018
    Inventors: Séverine Fagète, Oliver Hartley, Nicolas Fischer
  • Patent number: 9328153
    Abstract: The invention relates to polypeptides comprising an N-terminal portion and a C-terminal portion, wherein said N-terminal portion comprises the signature sequence QGP[P or L] and the amino acid sequence of said C-terminal portion is at least 70% identical to SEQ ID NO: 1, and uses thereof.
    Type: Grant
    Filed: June 4, 2013
    Date of Patent: May 3, 2016
    Assignee: Mintaka Foundation for Medical Research
    Inventor: Oliver Hartley
  • Patent number: 9198974
    Abstract: The present invention relates to a method for preparing decorated macromolecular scaffolds. The method of the invention is useful for the generation of bioactive nanoparticles for use in clinical applications. Such applications include drag and gene delivery, tumour targeting, bioimaging, tissue remodelling, generation of antiviral products and vaccines delivery.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: December 1, 2015
    Assignee: Mintaka Foundation for Medical Research
    Inventors: Hubert Gaertner, Oliver Hartley
  • Publication number: 20150291682
    Abstract: The invention relates to mimetic peptides of epitope(s) of Apolipoprotein A-I, diagnostic immunoassays comprising such mimetic peptides, as well as methods for diagnosing and methods for preventing and/or treating a cardiovascular disease.
    Type: Application
    Filed: November 6, 2013
    Publication date: October 15, 2015
    Inventors: Nicolas VUILLEUMIER, Sabrina PAGANO, Oliver HARTLEY, Hubert GAERTNER, Priscila CAMILLO TEIXEIRA, Paul CUTLER, Philippe FERBER
  • Publication number: 20140221569
    Abstract: The present invention relates to a method for preparing decorated macromolecular scaffolds. The method of the invention is useful for the generation of bioactive nanoparticles for use in clinical applications. Such applications include drag and gene delivery, tumour targeting, bioimaging, tissue remodelling, generation of antiviral products and vaccines delivery.
    Type: Application
    Filed: April 11, 2012
    Publication date: August 7, 2014
    Inventors: Hubert Gaertner, Oliver Hartley
  • Patent number: 8686111
    Abstract: The invention relates to polypeptides comprising an N-terminal portion and a C-terminal portion, wherein said N-terminal portion comprises the signature sequence QGP[P or L] and the amino acid sequence of said C-terminal portion is at least 70% identical to SEQ ID NO: 1, and uses thereof.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: April 1, 2014
    Assignee: Mintaka Foundation for Medical Research
    Inventor: Oliver Hartley
  • Publication number: 20130330305
    Abstract: The invention relates to polypeptides comprising an N-terminal portion and a C-terminal portion, wherein said N-terminal portion comprises the signature sequence QGP[P or L] and the amino acid sequence of said C-terminal portion is at least 70% identical to SEQ ID NO: 1, and uses thereof.
    Type: Application
    Filed: June 4, 2013
    Publication date: December 12, 2013
    Inventor: Oliver HARTLEY
  • Patent number: 8476406
    Abstract: The invention relates to polypeptides comprising an N-terminal portion and a C-terminal portion, wherein said N-terminal portion comprises the signature sequence QGP[P or L] and the amino acid sequence of said C-terminal portion is at least 70% identical to SEQ ID NO: 1, and uses thereof.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: July 2, 2013
    Assignee: Mintaka Foundation for Medical Research
    Inventor: Oliver Hartley
  • Patent number: 7915221
    Abstract: The present invention provides a method for the design and/or the selection of agonist or antagonist chemokine variants combining a phage display technology and a screening on living cells expressing the receptor of the corresponding native chemokine. It also provides RANTES variants having agonist properties towards said receptor, and methods for preventing and/or curing viral diseases, as well as clues for preventing and/or curing inflammatory or malignant diseases.
    Type: Grant
    Filed: April 2, 2007
    Date of Patent: March 29, 2011
    Assignee: Universite Pierre et Marie Curie (Paris VI)
    Inventors: Guy Gorochov, Oliver Hartley, Karim Dorgham, Patrice Debre, Robin Offord
  • Publication number: 20090075874
    Abstract: The present invention provides a method for the design and/or the selection of agonist or antagonist chemokine variants combining a phage display technology and a screening on living cells expressing the receptor of the corresponding native chemokine. It also provides RANTES variants having agonist properties towards said receptor, and methods for preventing and/or curing viral diseases, as well as clues for preventing and/or curing inflammatory or malignant diseases.
    Type: Application
    Filed: April 2, 2007
    Publication date: March 19, 2009
    Inventors: Guy Gorochov, Oliver Hartley, Karim Dorgham, Patrice Debre, Robin Offord
  • Patent number: 7211564
    Abstract: The present invention provides a method for the design and/or the selection of agonist or antagonist chemokine variants combining a phage display technology and a screening on living cells expressing the receptor of the corresponding native chemokine. It also provides RANTES variants having agonist properties towards said receptor, and methods for preventing and/or curing viral diseases, as well as clues for preventing and/or curing inflammatory or malignant diseases.
    Type: Grant
    Filed: March 4, 2004
    Date of Patent: May 1, 2007
    Assignees: Universite Pierre et Marie Curie (ParisVI), Universite De Geneve
    Inventors: Guy Gorochov, Oliver Hartley, Karim Dorgham, Patrice Debre, Robin Offord
  • Publication number: 20060252235
    Abstract: The invention provides a method of forming a polycrystalline semiconductor film on a supporting substrate of foreign material. The method involves depositing a metal film onto the substrate, forming a film of metal oxide and/or hydroxide on a substrate of the metal, and forming a layer of an amorphous semiconductor material over a surface of the metal oxide and/or hydroxide film. The entire sample is then heated to a temperature at which the semiconductor layer is absorbed into the metal layer and deposited as a polycrystalline layer onto the target surface by metal-induced crystallization. The metal is left as an overlayer covering the deposited polycrystalline layer, with semiconductor inclusions in the metal layer. The polycrystalline semiconductor film and the overlayer are generated by porous interfacial metal oxide nd/or hydroxide film.
    Type: Application
    Filed: October 7, 2003
    Publication date: November 9, 2006
    Inventors: Armin Aberle, Per Ingemar Widenborg, Axel Straub, Dirk-Holger Neuhaus, Oliver Hartley, Nils-Peter Harder
  • Publication number: 20050189013
    Abstract: A process for making a photovoltaic cell using a semiconductor wafer doped with a first dopant and having a front surface and a back surface, the process comprising the steps of forming a first layer on the front surface of the wafer, the first layer comprising a second dopant of a conductivity type opposite the first dopant; depositing a surface coating on the back surface; forming grooves in the front surface; adding dopant to the groove of a conductivity type opposite the first dopant subsequent to depositing the surface coating on the back surface; removing the surface coating from the back surface after adding dopant to the grooves; forming a back contact over the back surface after removal of the surface coating; and adding conductive material to the grooves.
    Type: Application
    Filed: December 17, 2004
    Publication date: September 1, 2005
    Inventor: Oliver Hartley
  • Publication number: 20040258659
    Abstract: The present invention provides a method for the design and/or the selection of agonist or antagonist chemokine variants combining a phage display technology and a screening on living cells expressing the receptor of the corresponding native chemokine. It also provides RANTES variants having agonist properties towards said receptor, and methods for preventing and/or curing viral diseases, as well as clues for preventing and/or curing inflammatory or malignant diseases.
    Type: Application
    Filed: March 4, 2004
    Publication date: December 23, 2004
    Inventors: Guy Gorochov, Oliver Hartley, Karim Dorgham, Patrice Debre, Robin Offord