Abstract: A portable system for producing a formulation comprising lipid nanoparticle (LNP)-encapsulated RNA includes: a first sub-system comprising multiple drug substance formulation modules, the first sub-system comprising: a transcription module for forming an RNA solution via in vitro transcription; and a second sub-system operatively downstream of the first sub-system comprising multiple drug product formation modules, the second sub-system comprising: an LNP formulation module for producing a first RNA-LNP preparation from the RNA solution, wherein each of the transcription module and the LNP formulation module is contained within a separate standard shipping container.

Abstract: A hydraulic unit, in particular a hydraulic unit for a slip-controllable vehicle brake system, includes a housing block, a pump, and a damping device. The pump has an intake side and a delivery side. The housing block has a pump receptacle that holds the pump, a first fluid duct that intersects the pump receptacle in a region of the delivery side of the pump, and a second fluid duct opening into the pump receptacle in the region of the delivery side of the pump, and a first separation point that seals off the first fluid duct from the second fluid duct. The damping device damps pulsations and reduces operating noise of the hydraulic unit without (i) having a detrimental effect on functional characteristics of the unit, in particular on pressure build-up dynamics of the vehicle brake system, or without (ii) jeopardizing a compact construction of the hydraulic unit.

Abstract: A piston pump, in particular as a pressure generator in an electronically slip-controllable vehicle brake system, includes a pump cylinder, a drivable piston, a pump working chamber, a valve space, and a valve. The drivable piston is slidably accommodated in the pump cylinder. The pump working chamber is bounded by the piston and the pump cylinder. The valve controls a supply of pressure medium to the pump working chamber. The valve has a conical valve seat and a closing element having a domed shell section that interacts with the valve seat. The valve seat surrounds the valve space, into which the closing element plunges, at least up to an imaginary center point of the domed shell section, when the valve seat is closed or open.

Abstract: A valve of a piston pump for a vehicle brake system having a closing body which is resiliently preloaded against a sealing seat. The closing body is formed in two parts with a damping piston and a closing element inserted therein. The damping piston is axially displaceably guided in a cylindrical piston guide. At least one flow channel is provided between the damping piston and the piston guide. The at least one flow channel is configured such that fluid can flow around the damping piston in the longitudinal direction thereof through the at least one flow channel.

Abstract: A hydraulic unit, in particular for a controllable-slip vehicle brake system, includes a housing block, a pump, a first fluid duct, and a second fluid duct. The housing block defines a pump receptacle that receives the pump, which has a suction side and a pressure side. The first duct crosses the pump receptacle in a region of the pressure side of the pump. The second duct leads into the pump receptacle in the region of the pressure side. The first and second ducts are sealed off from each over via a separation point. The hydraulic unit is configured to enable contact with a damping device configured to damp pulsations and reduce operating noise of the hydraulic unit without negatively impacting functional properties of the hydraulic unit, in particular on pressure build-up dynamics of the vehicle brake system, or without jeopardizing a compact construction of the hydraulic unit.

Abstract: A piston pump includes a perforated disk as a throttle, in a central hole of which an outlet valve is arranged and its inner edge is fixed externally on a cylinder sleeve base of the piston pump and an outer edge of which lies with prestress on an annular support. Brake fluid displaced out of the piston pump lifts the perforated disk-shaped throttle off from the annular support, with which a dynamic throttle is formed. A throttle channel which negotiates the annular support in the perforated disk-shaped throttle also enables a throughflow in the case of a throttle lying on the annular support.

Abstract: An aircraft refrigeration system comprises an ambient air line, through which ambient air flows and which is connected to conduct ambient air to an aircraft, an ambient air compressor, arranged in the ambient air line, for compressing the ambient air in the ambient air line, a cabin exhaust air turbine, connected to a cabin exhaust air line and coupled to the ambient air compressor in the ambient air line and configured to expand cabin exhaust air flowing through the cabin exhaust air line and to drive the ambient air compressor, a transmission, configured to couple the cabin exhaust air turbine to the ambient air compressor and to set a speed of the ambient air compressor, and a motor, coupled to the transmission and configured to drive the ambient air compressor.

Abstract: A device for choking a fluid flow includes a pot-like base body, in the base of which a first passage opening is arranged, and a closing body guided axially moveably in the pot-like base body against a spring force of a spring element and having a second passage opening that forms a static choke point with a predefined fixed opening cross section. The closing body in combination with the spring element and the first passage opening forms a dynamic choke point with a dynamic opening cross section that is variably adjustable depending on a pressure difference.

Abstract: A device for choking a fluid flow, with a pot-like base body, in the base of which a first passage opening is arranged, and a closing body guided axially moveably in the pot-like base body against a spring force of a spring element and having a second passage opening that forms a static choke point with a predefined fixed opening cross section. The closing body in combination with the spring element and the first passage opening forms a dynamic choke point with a dynamic opening cross section that is variably adjustable depending on a pressure difference.

Abstract: A piston pump, in particular as a pressure generator in an electronically slip-controllable vehicle brake system, includes a pump cylinder, a drivable piston, a pump working chamber, a valve space, and a valve. The drivable piston is slidably accommodated in the pump cylinder. The pump working chamber is bounded by the piston and the pump cylinder. The valve controls a supply of pressure medium to the pump working chamber. The valve has a conical valve seat and a closing element having a domed shell section that interacts with the valve seat. The valve seat surrounds the valve space, into which the closing element plunges, at least up to an imaginary center point of the domed shell section, when the valve seat is closed or open.

Abstract: A method for defining a structure of a photovoltaic system on a system surface with a local topology is provided, including: first placement of a block at a location on the system surface with the local topology; placing additional blocks at additional locations on the system surface without overlapping previously placed blocks, wherein prior to each placement, row spacing of the solar panels of each additional block is adapted to the topology at the location at which the respective additional block was placed, resulting in a change in the extension of the additional block in the direction of the column of solar panels of the additional block, and ending the placement of additional blocks if, by the placement of an additional block, the nominal capacity of a photovoltaic system corresponding to the structure were to be exceeded, or if no additional block can be placed without overlapping previously placed blocks.

Abstract: A device for choking a fluid flow includes a pot-like base body, in the base of which a first passage opening is arranged, and a closing body guided axially moveably in the pot-like base body against a spring force of a spring element and having a second passage opening that forms a static choke point with a predefined fixed opening cross section. The closing body in combination with the spring element and the first passage opening forms a dynamic choke point with a dynamic opening cross section that is variably adjustable depending on a pressure difference.

Abstract: A hydraulic unit, in particular a hydraulic unit for a slip-controllable vehicle brake system, includes a housing block, a pump, and a damping device. The pump has an intake side and a delivery side. The housing block has a pump receptacle that holds the pump, a first fluid duct that intersects the pump receptacle in a region of the delivery side of the pump, and a second fluid duct opening into the pump receptacle in the region of the delivery side of the pump, and a first separation point that seals off the first fluid duct from the second fluid duct. The damping device damps pulsations and reduces operating noise of the hydraulic unit without (i) having a detrimental effect on functional characteristics of the unit, in particular on pressure build-up dynamics of the vehicle brake system, or without (ii) jeopardizing a compact construction of the hydraulic unit.

Abstract: A valve of a piston pump, in particular for a hydraulic vehicle brake system, includes a closing body configured to be moved in an axially guided manner against a sealing seat. The closing body is formed in two pieces, which include a damping piston and a closing element inserted in the damping piston.

Abstract: A method and a device for controlling an energy-generating system are operated with a renewable energy source. In the method, a prediction about an energy yield of the energy-generating system is made for a predefined prediction time period, and a predefined area, using a learning system with an input vector and an output vector. The output vector includes operating variables for a multiplicity of successive future times of the time period. The input vector includes variables, influencing the operating variables, for a point in time from a multiplicity of points in time of a predefined observation time period. The input variables include at least three items of information for the observation time period and the predefined area. The energy-generating system is controlled on the basis of the generated prediction such that weather-conditioned fluctuations in the energy yield of the energy-generating system are reduced.

Abstract: A hydraulic unit, in particular for a controllable-slip vehicle brake system, includes a housing block, a pump, a first fluid duct, and a second fluid duct. The housing block defines a pump receptacle that receives the pump, which has a suction side and a pressure side. The first duct crosses the pump receptacle in a region of the pressure side of the pump. The second duct leads into the pump receptacle in the region of the pressure side. The first and second ducts are sealed off from each over via a separation point. The hydraulic unit is configured to enable contact with a damping device configured to damp pulsations and reduce operating noise of the hydraulic unit without negatively impacting functional properties of the hydraulic unit, in particular on pressure build-up dynamics of the vehicle brake system, or without jeopardizing a compact construction of the hydraulic unit.

Abstract: A method for creating a physical layout of a photovoltaic system in a specified field is provided where the photovoltaic system is specified by a plurality of technical properties. The method includes reading out more than 20 pre-calculated, completed layouts for the photovoltaic system from a memory; presenting the completed layouts in a graphical presentation wherein each of the completed layouts is represented by at least one partial amount of the plurality of technical properties; modifying value ranges of the presented technical properties, in order to present a modified number of completed layouts in a comparable manner; and selecting an optimized layout that has been optimized with regard to the presented properties from the modified number of completed layouts. Thereby a photovoltaic system having a high nominal power can be established in the best possible manner. The physical layout of the entire photovoltaic system is adapted to the specified field.

Abstract: A device for choking a fluid flow, with a pot-like base body, in the base of which a first passage opening is arranged, and a closing body guided axially moveably in the pot-like base body against a spring force of a spring element and having a second passage opening that forms a static choke point with a predefined fixed opening cross section. The closing body in combination with the spring element and the first passage opening forms a dynamic choke point with a dynamic opening cross section that is variably adjustable depending on a pressure difference.

Abstract: A piston pump includes a perforated disk as a throttle, in a central hole of which an outlet valve is arranged and its inner edge is fixed externally on a cylinder sleeve base of the piston pump and an outer edge of which lies with prestress on an annular support. Brake fluid displaced out of the piston pump lifts the perforated disk-shaped throttle off from the annular support, with which a dynamic throttle is formed. A throttle channel which negotiates the annular support in the perforated disk-shaped throttle also enables a throughflow in the case of a throttle lying on the annular support.

Abstract: A method and a device for controlling an energy-generating system are operated with a renewable energy source. In the method, a prediction about an energy yield of the energy-generating system is made for a predefined prediction time period, and a predefined area, using a learning system with an input vector and an output vector. The output vector includes operating variables for a multiplicity of successive future times of the time period. The input vector includes variables, influencing the operating variables, for a point in time from a multiplicity of points in time of a predefined observation time period. The input variables include at least three items of information for the observation time period and the predefined area. The energy-generating system is controlled on the basis of the generated prediction such that weather-conditioned fluctuations in the energy yield of the energy-generating system are reduced.