Abstract: The present invention relates to an electrophysiological measuring arrangement (100) and to an electrophysiological measuring method, in which a carrier (12) made of a carrier material (12?) and an aperture region (10) in the region of the carrier (12) are provided for the controlled sealing accumulation of a biological object (O). The aperture region (10) is formed with at least one aperture (14) and with a wall region (11) which, as the aperture inner wall (11i), surrounds the aperture (14), forming the latter.

Abstract: The invention relates to an electrophysiological measuring arrangement (100) and an electrophysiological measuring method in which a biological object (O) to be examined is sealingly deposited in a controllable manner on a support (12) of the measuring arrangement (100). A control electrode arrangement (20) is embedded in the interior of a wall region (11) which forms an aperture (14) of an aperture region (10). An electric potential can be applied to the control electrode arrangement in a controllable manner such that a surface charge of at least the inner wall (11i) of the wall region (10), said inner wall facing the aperture (14), can be generated in a controllable manner in terms of strength, variation over time, geometry, and/or polarity in order to thus prevent or support the sealing depositing process in a controlled manner in interaction with the membrane of the biological object (O) to be examined.