Patents by Inventor Osamu Soga

Osamu Soga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8685382
    Abstract: The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (hydroxyalkyl(meth) acrylamide mono/di-lactate_interpolymers. Another aspect of this invention is the application of such temperature sensitive polymers as release systems of biologically active compounds. The polymers of the present invention comprise monomers, which have modifiable functionality. The functionality of the monomers can for example be modified by the presence of hydrolysable groups. The modification is effected by the incubation, leading to a change of the water solubility characteristics of the polymer. The polymers used in the present invention contain hydrolysable chemical groups. As a result the polymer's solution characteristics, specifically its lower critical solution temperature (LCST), change upon incubation.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: April 1, 2014
    Assignee: Cristal Delivery B.V.
    Inventors: Wilhelmus Everhardus Hennink, Cornelis Franciscus Van Nostrum, Marinus Jacob Van Steenbergen, Osamu Soga, Cristianne Johanna Ferdinand Rijcken
  • Patent number: 8110220
    Abstract: The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly ploy (hydroxyalkyl (meth) acrylamide mono/di-lactate) interpolymers. Another aspect of this invention is the application of such temperature sensitive polymers as release systems of biologically active compounds. The polymers of the present invention comprise monomers, which have modifiable functionality. The functionality of the monomers can for example be modified by the presence of hydrolysable groups. The modification is effected by the incubation, leading to a change of the water solubility characteristics of the polymer. The polymers used in the present invention contain hydrolysable chemical groups. As a result the polymer's solution characteristics, specifically its lower critical solution temperature (LCST), change upon incubation.
    Type: Grant
    Filed: March 17, 2005
    Date of Patent: February 7, 2012
    Assignee: Universiteit Utrecht
    Inventors: Wilhelmus Everhardus Hennink, Cornelis Franciscus Van Nostrum, Marinus Jacob Van Steenbergen, Osamu Soga, Cristianne Johanna Ferdinand Rijcken
  • Publication number: 20120015034
    Abstract: The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (hydroxyalkyl(meth) acrylamide mono/di-lactate interpolymers. Another aspect of this invention is the application of such temperature sensitive polymers as release systems of biologically active compounds. The polymers of the present invention comprise monomers, which have modifiable functionality. The functionality of the monomers can for example be modified by the presence of hydrolysable groups. The modification is effected by the incubation, leading to a change of the water solubility characteristics of the polymer. The polymers used in the present invention contain hydrolysable chemical groups. As a result the polymer's solution characteristics, specifically its lower critical solution temperature (LCST), change upon incubation.
    Type: Application
    Filed: September 23, 2011
    Publication date: January 19, 2012
    Applicant: Universiteit Utrecht
    Inventors: Wilhelmus Everhardus HENNINK, Cornelis Franciscus Van Nostrum, Marinus Jacob Van Steenbergen, Osamu Soga, Cristianne Johanna Derdinand Rijcken
  • Patent number: 7425581
    Abstract: The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (N-(2-hydroxypropyl)methacrylamide mono/di-lactate) interpolymers. Another aspect of this invention is the application of such temperature sensitive polymers as release systems of biologically active compounds. The polymers of the present invention, comprise monomers which have modifiable functionality. The functionality of the monomers can for example be modified by the presence of hydrolysable groups. The modification is effected by the incubation, leading to a change of the water solubility characteristics of the polymer. The polymers used in the present invention contain hydrolysable chemical groups. As a result the polymer's solution characteristics, specifically its lower critical solution temperature (LCST), change upon incubation.
    Type: Grant
    Filed: March 18, 2004
    Date of Patent: September 16, 2008
    Assignee: Universiteit Utrecht
    Inventors: Wilhelmus Everardus Hennink, Cornelus Franciscus Van Nostrum, Marinus Jacob Van Steenbergen, Osamu Soga
  • Publication number: 20080050435
    Abstract: The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly ploy (hydroxyalkyl (meth) acrylamide mono/di-lactate) interpolymers. Another aspect of this invention is the application of such temperature sensitive polymers as release systems of biologically active compounds. The polymers of the present invention comprise monomers, which have modifiable functionality. The functionality of the monomers can for example be modified by the presence of hydrolysable groups. The modification is effected by the incubation, leading to a change of the water solubility characteristics of the polymer. The polymers used in the present invention contain hydrolysable chemical groups. As a result the polymer's solution characteristics, specifically its lower critical solution temperature (LCST), change upon incubation.
    Type: Application
    Filed: March 17, 2005
    Publication date: February 28, 2008
    Inventors: Wilhelmus Everhardus Hennink, Cornelis Franciscus Van Nostrum, Marinus Jacob Van Steenbergen, Osamu Soga
  • Publication number: 20040247670
    Abstract: The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (N-(2-hydroxypropyl)methacrylamide mono/di-lactate) interpolymers. Another aspect of this invention is the application of such temperature sensitive polymers as release systems of biologically active compounds. The polymers of the present invention, comprise monomers which have modifiable functionality. The functionality of the monomers can for example be modified by the presence of hydrolysable groups. The modification is effected by the incubation, leading to a change of the water solubility characteristics of the polymer. The polymers used in the present invention contain hydrolysable chemical groups. As a result the polymer's solution characteristics, specifically its lower critical solution temperature (LCST), change upon incubation.
    Type: Application
    Filed: March 18, 2004
    Publication date: December 9, 2004
    Inventors: Wilhelmus Everardus Hennink, Cornelus Franciscus Van Nostrum, Marinus Jacob Van Steenbergen, Osamu Soga