Abstract: An observation coordinate in the device coordinate system of an observation device is converted into an observation coordinate in a virtual coordinate system, using a conversion formula. Subsequently, the observation coordinate in the virtual coordinate system is converted into an observation coordinate in the device coordinate system of another observation device, using a reverse conversion formula. The virtual coordinate system is a logical coordinate system that does not depend on any device coordinate system.

Abstract: Each of mechanical seal devices of a rotary joint includes a seal ring and a seal ring attached to a shaft body, and a seal ring and a seal ring attached to a case body. A flow passage that partitions an annular space and connects a flow passage and a flow passage is formed between a sliding portion of the seal rings and a sliding portion of the seal rings. A flow passage that partitions the annular space and connects a flow passage and a flow passage is formed between the sliding portion of a mechanical seal device disposed on one side in the axial direction and the sliding portion of a mechanical seal device disposed on the other side in the axial direction in mechanical seal devices adjacent to each other in the axial direction.

Abstract: A bone regeneration material according to the present disclosure includes at least a composite of octacalcium phosphate (OCP) particles and gelatin, and is a porous body having a plurality of pores. The particle size of the octacalcium phosphate particles is 1 ?m or more but less than 1 mm, and the molecular weight of the gelatin is in the range of 30 kDa to 70 kDa. Thus, the material is able to resist breaking down during implantation and exhibit high handleability.

Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X1 represents —N? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.

Abstract: Provided is a rotary joint capable of lubricating a sealing surface of a mechanical seal forming a fluid passage through which a gas flows using a liquid even when the liquid flows through only one fluid passage. A rotary joint 1 includes a plurality of mechanical seals 7 provided in an axial direction in an annular space A between a case body 2 and a shaft body 5 to form a first intermediate flow passage 41 that connects a first outer flow passage 31 and a first inner flow passage 61 of a first fluid passage 11 through which a liquid flows to each other and form a second intermediate flow passage 42 that connects a second outer flow passage 32 and a second inner flow passage 62 of a second fluid passage 12 through which a gas flows to each other.

Abstract: A semiconductor device includes an electrode having a flat part and a non-flat part made up of a concave part, a joint layer being made of a sintered body of metal crystal grains provided on the flat part and the non-flat part of the electrode, and a semiconductor element being joined to the electrode with the joint layer therebetween, wherein the joint layer has a first region sandwiched between the non-flat part and the semiconductor element and a second region sandwiched between the flat part and the semiconductor element, and either one of the first region and the second region having a larger film thickness has a filling rate of the metal crystal grains smaller than the other one of the first region and the second region having a smaller film thickness. The present invention enhances reliability of a joint layer made of a sintered body of metal crystal grains.

Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X represents —N? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.

Abstract: [Problem] An object is to provide novel composite copper foils. [Means to solve the problem] A composite copper foil comprises a copper foil and a layer of metal other than copper, the metal layer being formed on at least a part of a surface of the copper foil, wherein at least a part of the composite copper foil has protrusions on a surface thereof, and each protrusion has a height of 10 nm or more but 1000 nm or less in a cross-section of the composite copper foil.

Abstract: The present invention provides a plasticizer for a vinyl chloride resin including an ester compound (A1) represented by General Formula (1): (in the formula, L's each represent an aliphatic oxycarboxylic acid residue having 3 to 18 carbon atoms or a cyclic ester residue having 3 to 18 carbon atoms, R1's each represent an alkyl group having 6 to 18 carbon atoms, R2's each represent a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, a represents a repeating number of the L, provided that the total of the plural a's is from 1 to 10, and x is an integer of 2 to 4), in order to provide a plasticizer for a vinyl chloride which has excellent compatibility with vinyl chloride resins and with which a vinyl chloride resin composition capable of providing a molded article having excellent freeze resistance and heat resistance can be obtained.

Abstract: A semiconductor device includes an electrode having a flat part and a non-flat part made up of a concave part, a joint layer being made of a sintered body of metal crystal grains provided on the flat part and the non-flat part of the electrode, and a semiconductor element being joined to the electrode with the joint layer therebetween, wherein the joint layer has a first region sandwiched between the non-flat part and the semiconductor element and a second region sandwiched between the flat part and the semiconductor element, and either one of the first region and the second region having a larger film thickness has a filling rate of the metal crystal grains smaller than the other one of the first region and the second region having a smaller film thickness. The present invention enhances reliability of a joint layer made of a sintered body of metal crystal grains.

Abstract: A rotary joint includes a tubular case body, an outer cylinder body provided to be relatively rotatable inside the case body, an inner shaft body provided to be relatively rotatable inside the outer cylinder body, a first mechanical seal for forming flow passages that connect a first flow passage of the case body and a second flow passage of the outer cylinder body to each other by dividing a first annular space formed between the case body and the outer cylinder body, and a second mechanical seal for forming flow passages that connect a third flow passage of the outer cylinder body and a fourth flow passage of the inner shaft body to each other by dividing a second annular space formed between the outer cylinder body and the inner shaft body.

Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X1 represents —NH? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.

Abstract: A semiconductor device includes an electrode having a flat part and a non-flat part made up of a concave part, a joint layer being made of a sintered body of metal crystal grains provided on the flat part and the non-flat part of the electrode, and a semiconductor element being joined to the electrode with the joint layer therebetween, wherein the joint layer has a first region sandwiched between the non-flat part and the semiconductor element and a second region sandwiched between the flat part and the semiconductor element, and either one of the first region and the second region having a larger film thickness has a filling rate of the metal crystal grains smaller than the other one of the first region and the second region having a smaller film thickness. The present invention enhances reliability of a joint layer made of a sintered body of metal crystal grains.

Abstract: Provided are: a dispersant for calcium carbonate that is capable of dispersing calcium carbonate well in a thermoplastic resin; a calcium carbonate composition and a thermoplastic resin composition that each contain the dispersant for calcium carbonate; and a molded body produced by using the thermoplastic resin composition. Specifically, provided are a dispersant for calcium carbonate, including a polyester resin containing an aromatic dicarboxylic acid residue, an aliphatic diol residue, and a monoalcohol residue or a monocarboxylic acid residue and having a melting point of 100 to 250° C.; a calcium carbonate composition that contains the dispersant and calcium carbonate; a thermoplastic resin composition that contains the dispersant, calcium carbonate, and a thermoplastic resin; and a molded body that contains the thermoplastic resin composition.

Abstract: [Problem] To provide a therapeutic method specialized for an inflammatory disease such as intractable vasculitis and an infectious disease, which is different from the previous therapeutic methods, in which a target molecule was not determined, by determining the target molecule useful for treating these diseases. [Solution] According to one aspect of the present invention, a prophylactic and/or therapeutic agent for an infectious disease or an inflammatory disease which contains an antibody recognizing apolipoprotein a2 (APOA2) as an active ingredient is provided.

Abstract: In order to provide a polyester resin having excellent flexibility, transparency, solvent resistance, heat resistance, and water resistance and capable of being used for a protective layer of a fabric, and a resin-clad fabric obtained by forming a layer of the polyester resin on a fabric, the present invention provides a polyester resin including: a dicarboxylic acid residue; and a glycol residue, in which the dicarboxylic acid residue includes a terephthalic acid residue (a), an aliphatic dicarboxylic acid residue (b) having 6 to 12 carbon atoms, and a dimer acid residue or hydrogenated dimer acid residue (c), the glycol residue includes an ethylene glycol residue or diethylene glycol residue (d) and a branched aliphatic glycol residue (e) having 3 to 9 carbon atoms.

Abstract: A roller shaft is inserted into a mold including molding members respectively having a first mold surface that defines an outer circumference of a roller portion and second and third mold surfaces that respectively define first and second flat portions of the roller portion, and the mold is then closed. A molding material is injected around the roller shaft to integrally mold the roller portion. The roller portion includes the outer circumference and the first and second flat portions rising from the roller shaft to the outer circumference. The roller shaft includes flange portions at portions corresponding to the first and second flat portions. The flange portions prevent the molding material from leaking outside the first and second flat portions when the roller portion is integrally molded around the roller shaft by injection molding.

Abstract: A roller shaft is inserted into a mold including molding members respectively having a first mold surface that defines an outer circumference of a roller portion and second and third mold surfaces that respectively define first and second flat portions of the roller portion, and the mold is then closed. A molding material is injected around the roller shaft to integrally mold the roller portion. The roller portion includes the outer circumference and the first and second flat portions rising from the roller shaft to the outer circumference. The roller shaft includes flange portions at portions corresponding to the first and second flat portions. The flange portions prevent the molding material from leaking outside the first and second flat portions when the roller portion is integrally molded around the roller shaft by injection molding.

Abstract: An optical sensor disposition structure for a saddle riding vehicle includes an optical sensor, and an airflow guide member disposed in front of a head pipe and configured to cover a front section of a vehicle body and in which an introduction port configured to guide traveling air rearward is formed, wherein the optical sensor overlaps the introduction port when seen in a front view.

Abstract: The present invention relates to a novel azole derivative as an apelin receptor agonist and a method for treating cardiovascular disease, diabetic disease, renal disease, hypertension, and arteriosclerosis, etc., using the same. The present invention provides a compound represented by formula (I) or a pharmacologically acceptable salt thereof wherein X1 represents —NH? or —CH?, X2 represents —CH? or —N?, R1 and R2 each represent a C1 to C6 alkoxy group or the like, R3 represents a heteroaryl group (the heteroaryl group is optionally substituted by a methyl group or the like) or the like, and R4 represents a C1 to C6 alkylthio group or a C2 to C6 alkenyl group (the C1 to C6 alkylthio group and the C2 to C6 alkenyl group are each optionally substituted by one carboxy group or the like) or the like.