Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: The present disclosure relates to compression clips, and more specifically, to compression clips delivered to a target site through an endoscope for use in tissue resection, for example, within the gastrointestinal tract. In examples, clips are configured to be actuatable in response to a compressive force to transition between an open configuration and a closed configuration. In an embodiment, a tissue clipping device may include a first member with a plurality of arms. Each of the arms may extend from a first end to a second end, and the first end of each arm may be received within the first member. The arms may be movable between the open configuration and the closed configuration. A second member may be slidably disposed with respect to the first member.

Abstract: The present disclosure relates to compression clips, and more specifically, to compression clips delivered to a target site through an endoscope for use in tissue resection, for example, within the gastrointestinal tract. In examples, clips are configured to be actuatable in response to a compressive force to transition between an open configuration and a closed configuration. In an embodiment, a tissue clipping device may include a first member with a plurality of arms. Each of the arms may extend from a first end to a second end, and the first end of each arm may be received within the first member. The arms may be movable between the open configuration and the closed configuration. A second member may be slidably disposed with respect to the first member.

Abstract: A device may include an elongated housing formed of an optically transparent material, the housing extending from a proximal end to a distal end and including a lateral wall extending from the proximal end to a distal tip of the housing, the housing defining a lumen extending into the housing from a proximal opening in the proximal end of the housing. The device also may include a first port extending through the lateral wall of the housing to open the lumen of the housing to an exterior of the housing, the first port being sized and shaped to receive therein a target portion of tissue to be inspected and/or treated.

Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and resuable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: The present disclosure relates to the field of endoscopy. Specifically, the present disclosure relates to systems and methods for en bloc resection of malignant and pre-malignant lesions and/or tumors within the gastrointestinal (GI) tract. More specifically, the present disclosure relates to systems and methods for delivering an expandable scaffold between tissue layers (e.g., between the muscularis and submucosa layers) to elevate and stabilize the lesion or tumor for fast and efficient resection.

Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: The present disclosure is directed to a tissue removal device. The tissue removal device may include a distal portion. The distal portion may include an outer distal portion including a tissue removal tool, and an inner distal portion positioned within the outer distal portion and having a closed distal end, a lumen, and at least one side port, wherein the lumen is configured to receive a medical device, and the inner distal portion is movable relative to the outer distal portion and the medical device.

Abstract: Various embodiments are generally directed to positioning techniques to facilitate entry of a flexible elongate member (e.g., endoscopic accessory tool) into and/or through selected anatomies, such as by directing a set of positional controls based on feedback from a set of transducers to achieve or maintain a position within a body lumen, for instance. Some embodiments are particularly directed to a feedback loop for positioning or guiding a flexible elongate member into a target configuration for one or more of inspection, orientation, and/or facilitating access to body passageways. In one embodiment, for example, a device manager may include circuitry to operate at least one positional control in a set of positional controls based on data indicative of a current configuration of a flexible elongate member generated by a set of transducers.

Abstract: A device includes a handle having a trigger in combination with a distal portion, the distal portion including a rigid elongated hollow member which receives tissue therein and a plunger fitted with and configured to slide longitudinally within the hollow member to induce suction at a distal end of the hollow member as the plunger is moved proximally within the hollow member. The trigger is hingedly coupled to the plunger so that pulling the trigger slides the plunger proximally with respect to the hollow member to generate suction to draw the tissue into the distal end of the hollow member. The device further includes a tissue treatment mechanism for encircling the tissue received at the distal end of the hollow member.

Abstract: According to an embodiment of the present disclosure, a medical device for deploying a ligation band may include a tubular body. The tubular body may include a proximal end, a distal end, a radially inner surface defining a lumen through the tubular body, and a radially outer surface. The radially outer surface may include protrusions arranged in rows extending at least partially around a proximal region of the radially outer surface. Protrusions in adjacent rows may be separated by a first distance. Surface features may extend at least partially around a distal region of the radially outer surface. Adjacent surface features may be separated by a second distance larger than the first distance.

Abstract: The present disclosure relates to compression clips, and more specifically, to compression clips delivered to a target site through an endoscope for use in tissue resection, for example, within the gastrointestinal tract. In examples, clips are configured to be actuatable in response to a compressive force to transition between an open configuration and a closed configuration. In an embodiment, a tissue clipping device may include a first member with a plurality of arms. Each of the arms may extend from a first end to a second end, and the first end of each arm may be received within the first member. The arms may be movable between the open configuration and the closed configuration. A second member may be slidably disposed with respect to the first member.

Abstract: A rapid exchange catheter comprises a guide wire lumen including a substantially sealed portion in which a lumen wall extends around an entire periphery thereof and a channel portion including a channel opening the lumen to an exterior of the catheter, wherein a width of the channel is less than a maximum width of the channel portion. A guide wire ramp extends into the channel portion, with the ramp extending further into the lumen of the channel portion as a distal end of the ramp is approached.

Abstract: A device for accessing tissue within a body lumen comprises an elongated body portion defining a lumen and an anchoring mechanism including an expanding structure on a distal portion of the elongated body portion. The anchoring mechanism moves the expanding structure from an insertion configuration in which the expanding structure is constricted against the device to an operative configuration in a body in which the expanding structure expands away from the device without altering a length of the anchoring mechanism in combination with a control mechanism for selectively engaging the anchoring mechanism.

Abstract: A device for collecting a tissue sample includes a needle body extending along a longitudinal axis from a proximal end to a distal end and including a channel extending longitudinally therethrough and a plurality of cut outs extending laterally into the needle body, each of the plurality of cut outs extending at an angle relative to the longitudinal axis from an outer surface of the needle body toward the distal end thereof so that the channel is open to an exterior of the needle body via the plurality of cut outs.

Abstract: According to an embodiment of the present disclosure, a medical device for deploying a ligation band may include a tubular body. The tubular body may include a proximal end, a distal end, a radially inner surface defining a lumen through the tubular body, and a radially outer surface. The radially outer surface may include protrusions arranged in rows extending at least partially around a proximal region of the radially outer surface. Protrusions in adjacent rows may be separated by a first distance. Surface features may extend at least partially around a distal region of the radially outer surface. Adjacent surface features may be separated by a second distance larger than the first distance.

Abstract: According to an embodiment of the present disclosure, a medical device for deploying a ligation band may include a tubular body. The tubular body may include a proximal end, a distal end, a radially inner surface defining a lumen through the tubular body, and a radially outer surface. The radially outer surface may include protrusions arranged in rows extending at least partially around a proximal region of the radially outer surface. Protrusions in adjacent rows may be separated by a first distance. Surface features may extend at least partially around a distal region of the radially outer surface. Adjacent surface features may be separated by a second distance larger than the first distance.