Patents by Inventor Pablo D. CARDENAS

Pablo D. CARDENAS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYCOALKALOID METABOLISM ENYZYMES (GAMES) AND USES THEREOF
    Publication number: 20190367940
    Abstract: Disclosed herein are genetically modified plants having altered biological activity of 3-?-hydroxysteroid dehydrogenase/isomerase (GAME25), or 2-oxoglutarate-dependent dioxygenase (GAME31), or a combination thereof, wherein the genetically modified plants have an altered content of at least one cholesterol derived compound selected from the group including a steroidal alkaloid or a glycosylated derivative thereof and an unsaturated or saturated steroidal saponin or a glycoside derivative thereof. Further disclosed herein are genetically modified plants having altered expression of a gene encoding a 3-?-hydroxysteroid dehydrogenase/isomerase (GAME25), or a 2-oxoglutarate-dependent dioxygenase (GAME31), or a combination thereof, wherein the genetically modified plant has an altered content of at least one cholesterol derived compound selected from the group including a steroidal alkaloid or a glycosylated derivative thereof and an unsaturated or saturated steroidal saponin or a glycoside derivative thereof.
    Type: Application
    Filed: February 8, 2018
    Publication date: December 5, 2019
    Applicants: YEDA RESEARCH AND DEVELOPMENT CO. LTD., Yissum Research Development Company, of The Hebrew University of Jerusalem Ltd.
    Inventors: Asaph AHARONI, Prashant SONAWANE, Pablo D. CARDENAS, BURDMAN Saul