Patents by Inventor Pamela A. Marshall

Pamela A. Marshall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC COMPOUNDS
    Publication number: 20230322688
    Abstract: The invention provides compounds formula (I) and salts thereof: wherein R1-R2 have any of the values defined in the specification. The compounds are useful for treating conditions including Alzheimer? s disease, Parkinson’s disease, diabetes, cancer, inflammation, hyperresponsiveness, allergic conditions, asthma, and psychotic disorders such as schizophrenia. The compounds are also useful to lower IL-4, IL-5, or IL-15 levels in an animal.
    Type: Application
    Filed: September 8, 2021
    Publication date: October 12, 2023
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl E. WAGNER, Peter W. JURUTKA, Pamela A. MARSHALL
  • Compositions Comprising a Retinoid X Receptor (RXR) Agonist, a Retinoic Acid Receptor (RAR) Agonist, or a Dual RXR/RAR Agonist
    Publication number: 20220259157
    Abstract: The present invention relates to compositions comprising an RXR agonist, an RAR agonist, or a dual RXR/RAR agonist. The present invention further relates to methods of using the agonist compositions for treating or preventing dementia and cancer. In some embodiments, the dementia comprises Alzheimer's disease. In some embodiments, the cancer comprises leukemia.
    Type: Application
    Filed: June 24, 2020
    Publication date: August 18, 2022
    Inventors: Carl Wagner, Pamela Marshall, Peter Jurutka
  • Substituted anilines for treatment of animal diseases
    Patent number: 10787421
    Abstract: The invention provides compounds formula (I) and salts thereof: wherein R1-R4 have any of the values defined in the specification. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, inflammation, hyperresponsiveness, allergic conditions, asthma, and psychotic disorders such as schizophrenia. The compounds are also useful to lower IL-4, IL-5, or IL-15 levels in an animal.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: September 29, 2020
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl Wagner, Peter Jurutka, Pamela Marshall
  • Therapeutic compounds
    Patent number: 10391093
    Abstract: The invention provides compounds of formulae I, II, III, and IV: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers and Alzheimer's disease.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: August 27, 2019
    Assignee: ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl E. Wagner, Peter W. Jurutka, Pamela A. Marshall
  • THERAPEUTIC COMPOUNDS
    Publication number: 20190218190
    Abstract: The invention provides compounds formula (I) and salts thereof: wherein R1-R4 have any of the values defined in the specification. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, inflammation, hyperresponsiveness, allergic conditions, asthma, and psychotic disorders such as schizophrenia. The compounds are also useful to lower IL-4, IL-5, or IL-15 levels in an animal.
    Type: Application
    Filed: January 15, 2019
    Publication date: July 18, 2019
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl WAGNER, Peter JURUTKA, Pamela MARSHALL
  • Therapeutic methods
    Patent number: 10328040
    Abstract: The invention provides a method for a disease or condition associated with dopamine deficiency (e.g. depression, schizophrenia, or Parkinson's disease) in a mammal in need of such treatment comprising administering a compound that binds to RXR to the mammal.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: June 25, 2019
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Pamela Marshall, Peter Jurutka, Carl Wagner
  • Dihydroindene and tetrahydronaphthalene compounds
    Patent number: 10238655
    Abstract: The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: March 26, 2019
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl E. Wagner, Pamela A. Marshall, Peter W. Jurutka
  • Therapeutic compounds
    Patent number: 10238626
    Abstract: The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: March 26, 2019
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl E. Wagner, Pamela A. Marshall, Peter W. Jurutka
  • Isochroman compounds and methods of use thereof
    Patent number: 10231947
    Abstract: The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: March 19, 2019
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl E. Wagner, Pamela A. Marshall, Peter W. Jurutka
  • Substituted anilines for treatment of animal diseases
    Patent number: 10221143
    Abstract: The invention provides alkyl benzene compounds. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, inflammation, hyperresponsiveness, allergic conditions, asthma, and psychotic disorders such as schizophrenia. The compounds are also useful to lower IL-4, IL-5, or IL-15 levels in an animal.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: March 5, 2019
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl Wagner, Peter Jurutka, Pamela Marshall
  • Therapeutic compounds
    Patent number: 10112917
    Abstract: The invention provides compounds formula (I) and salts thereof: wherein the bond represented by ---- is a single bond or a double bond, and R1 has any of the values defined in the specification. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, and psychotic disorders such as schizophrenia.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: October 30, 2018
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl Wagner, Peter Jurutka, Pamela Marshall
  • THERAPEUTIC COMPOUNDS
    Publication number: 20180207126
    Abstract: The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.
    Type: Application
    Filed: January 23, 2018
    Publication date: July 26, 2018
    Inventors: Carl E. Wagner, Pamela A. Marshall, Peter W. Jurutka
  • DIHYDROINDENE AND TETRAHYDRONAPHTHALENE COMPOUNDS
    Publication number: 20180207156
    Abstract: The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.
    Type: Application
    Filed: January 23, 2018
    Publication date: July 26, 2018
    Inventors: Carl E. Wagner, Pamela A. Marshall, Peter W. Jurutka
  • ISOCHROMAN COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20180207125
    Abstract: The invention provides compounds of formula I: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers, Alzheimer's disease, and conditions associated with demyelination.
    Type: Application
    Filed: January 23, 2018
    Publication date: July 26, 2018
    Inventors: Carl E. Wagner, Pamela A. Marshall, Peter W. Jurutka
  • Therapeutic compounds
    Patent number: 10005741
    Abstract: The invention provides compounds and compositions that are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, and psychotic disorders such as schizophrenia.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: June 26, 2018
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl Wagner, Pamela Marshall, Peter Jurutka
  • THERAPEUTIC COMPOUNDS
    Publication number: 20180141921
    Abstract: The invention provides compounds and compositions that are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, and psychotic disorders such as schizophrenia.
    Type: Application
    Filed: January 17, 2018
    Publication date: May 24, 2018
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl WAGNER, Pamela MARSHALL, Peter JURUTKA
  • THERAPEUTIC COMPOUNDS
    Publication number: 20180072697
    Abstract: The invention provides compounds formula (I) and salts thereof: wherein the bond represented by ---- is a single bond or a double bond, and R1 has any of the values defined in the specification. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, and psychotic disorders such as schizophrenia.
    Type: Application
    Filed: March 1, 2016
    Publication date: March 15, 2018
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl WAGNER, Peter JURUTKA, Pamela MARSHALL
  • THERAPEUTIC COMPOUNDS
    Publication number: 20180065936
    Abstract: The invention provides compounds formula (I) and salts thereof: wherein R1-R4 have any of the values defined in the specification. The compounds are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, inflammation, hyperresponsiveness, allergic conditions, asthma, and psychotic disorders such as schizophrenia. The compounds are also useful to lower IL-4, IL-5, or IL-15 levels in an animal.
    Type: Application
    Filed: March 1, 2016
    Publication date: March 8, 2018
    Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl WAGNER, Peter JURUTKA, Pamela MARSHALL
  • Therapeutic compounds
    Patent number: 9908856
    Abstract: The invention provides compounds and compositions that are useful for treating conditions including Alzheimer's disease, Parkinson's disease, diabetes, cancer, and psychotic disorders such as schizophrenia.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: March 6, 2018
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Carl Wagner, Pamela Marshall, Peter Jurutka
  • THERAPEUTIC COMPOUNDS
    Publication number: 20170182046
    Abstract: The invention provides compounds of formulae I, II, III, and IV: and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers and Alzheimer's disease.
    Type: Application
    Filed: January 4, 2017
    Publication date: June 29, 2017
    Applicant: Arizona Board of Regents, A Body Corporate of the State of Arizona, Acting For and On Behalf of Ariz
    Inventors: Carl E. Wagner, Peter W. Jurutka, Pamela A. Marshall