Patents by Inventor Paola Vianello

Paola Vianello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrrolo[3,4-c]pyrazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
    Publication number: 20050032839
    Abstract: Pyrrolo[3,4-c]pyrazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
    Type: Application
    Filed: July 1, 2004
    Publication date: February 10, 2005
    Applicant: Pharmacia Italia S.p.A.
    Inventors: Daniele Fancelli, Barbara Forte, Jurgen Moll, Mario Varasi, Paola Vianello
  • Pyrazolyl-indole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
    Publication number: 20050032869
    Abstract: Pyrazolyl-indole derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
    Type: Application
    Filed: July 1, 2004
    Publication date: February 10, 2005
    Applicant: Pharmacia Italia S.p.A.
    Inventors: Daniela Berta, Barbara Forte, Sergio Mantegani, Mario Varasi, Paola Vianello
  • Novel substituted benzoxazines as integrin antagonists
    Publication number: 20040224948
    Abstract: The present invention relates to a class of compounds represented by the formula (I) 1
    Type: Application
    Filed: April 8, 2004
    Publication date: November 11, 2004
    Inventors: Paola Vianello, Tiziano Bandiera
  • Benzoxazine derivatives useful as integrin receptor antagonists
    Patent number: 6794385
    Abstract: The present invention relates to a class of compounds represented by the formula (I) or a pharmaceutical acceptable salt, prodrug or ester thereof, pharmaceutical compositions comprising compounds of the formula (I), and methods of selectively inhibiting or antagonizing &agr;v&bgr;3 integrin.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: September 21, 2004
    Assignee: Pharmacia & Upjohn, S.p.A.
    Inventors: Paola Vianello, Tiziano Bandiera, Mario Varasi
  • Substituted benzoxazines as integrin antagonists
    Patent number: 6750215
    Abstract: The present invention relates to a class of compounds represented by the formula (I) or a pharmaceutical acceptable salt, prodrug or ester thereof, pharmaceutical compositions comprising compounds of the formula (I), and methods of selectively inhibiting or antagonizing &agr;v&bgr;3 integrin.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: June 15, 2004
    Assignee: Pharmacia & Upjohn, S.p.A.
    Inventors: Paola Vianello, Tiziano Bandiera
  • Propanoic acid derivatives as intergrin receptor antagonists
    Publication number: 20030144311
    Abstract: Novel propanoic acid derivatives are integrin receptor antagonists or inhibitors, in particular of the avb3 integrin receptor. The compounds of the invention are for instance useful for the treatment of solid tumors by inhibition of angiogenic growth of tumor vessel network, thus promoting tumor regression, inhibition of metastatic spread, thus avoiding cancer metastases, inhibition of bone resorption, thus controlling osteoporosis, inhibition of smooth muscle cells migration into neointima, thus blocking restenosis after percutaneous coronary angioplasty and the treatment of other pathological conditions mediated by cell adhesion, cell migration or angiogenesis such e.g. diabetic retinopaty, rheumatoid arthritis and inflammation.
    Type: Application
    Filed: November 1, 2002
    Publication date: July 31, 2003
    Inventors: Tiziano Bandiera, Paola Vianello, Paolo Cozzi, Arturo Galvani
  • Novel substituted benzoxazines as integrin antagonists
    Publication number: 20030073688
    Abstract: The present invention relates to a class of compounds represented by the formula (I) 1
    Type: Application
    Filed: August 8, 2001
    Publication date: April 17, 2003
    Inventors: Paola Vianello, Tiziano Bandiera
  • New benzoxazine derivatives useful as integrin receptor antagonists
    Publication number: 20030069236
    Abstract: The present invention relates to a class of compounds represented by the formula (I) 1
    Type: Application
    Filed: August 8, 2001
    Publication date: April 10, 2003
    Inventors: Paola Vianello, Tiziano Bandiera, Mario Varasi
  • Deoxynojirimycin derivatives and their uses as glucosylceramidase inhibitors
    Patent number: 6177447
    Abstract: Deoxynojirimycin derivatives containing a large hydrophobic moiety, such as cholesterol or adamantame-methanol, linked through a spacer, such as pentamethylene, to the nitrogen atom of deoxynojirimycin, and salts thereof, inhibit glucosylceramidase and may be useful in the treatment of diseases involving a ceramide-mediated signaling process, such as Gaucher disease.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: January 23, 2001
    Assignee: Universiteit van Amsterdam
    Inventors: Johannes Maria F. G. Aerts, Upendra Kumar Pandit, Gerrit-Jan Koomen, Herman Steven Overkleeft, Paola Vianello
  • 9,10-diazatricyclo[4,4,1,1.sup.2,5 ] decane and 2,7-diazatricyclo [4,4,0,0.sup.3,8 ] decane derivatives having analgesic activity
    Patent number: 6127362
    Abstract: 9,10-DIAZATRICYCLO[4,4,1,1.sup.2,5 ]DECANE (la) AND 2,7-DIAZATRICYCLO[4,4,0,0.sup.3,8 ]DECANE (1b) DERIVATIVES HAVING ANALGESIC ACTIVITY.
    Type: Grant
    Filed: December 2, 1999
    Date of Patent: October 3, 2000
    Assignee: Neuroscienze S.C.A.R.L.
    Inventors: Giorgio Cignarella, Paola Vianello