Patents by Inventor Pascal CHALUS

Pascal CHALUS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11454609
    Abstract: A method of evaluating a solid fraction of a target pharmaceutical sample by means of a solid fraction sensor is disclosed with the solid fraction sensor including a first conductor element, a second conductor element, an operation space and an energy source arranged to generate an electric field in the operation space by means of the first conductor element and the second conductor element. The method including positioning the target pharmaceutical sample in the operation space of the solid fraction sensor, determining a capacitance between the first and second conductor element with the target pharmaceutical sample located in the operation space, and converting the determined capacitance together with information about a composition of a reference pharmaceutical sample having the essentially same dielectric properties as the target pharmaceutical sample and about a thickness of the reference pharmaceutical sample into a solid fraction of the target pharmaceutical sample.
    Type: Grant
    Filed: September 21, 2018
    Date of Patent: September 27, 2022
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Juraj Sibik, Pascal Chalus
  • Publication number: 20200276087
    Abstract: A pharmaceutical manufacturing installation, including a processing equipment arranged to provide a pharmaceutical substance in a solid state and a solid fraction sensor is disclosed. The solid fraction sensor having a first conductor element, a second conductor element, an operation space, an energy source arranged to generate an electric field in the operation space by means of the first conductor element and the second conductor element, and a controller adapted to determine a capacitance between the first and second conductor element of the pharmaceutical substance in the solid state located in the operation space. The solid fraction sensor is arranged to receive the pharmaceutical substance in its solid state into the operation space by the processing equipment.
    Type: Application
    Filed: September 20, 2018
    Publication date: September 3, 2020
    Inventors: Juraj SIBIK, Pascal CHALUS
  • Publication number: 20200217811
    Abstract: For the use of a solid fraction sensor (17) to evaluate a solid fraction of a target pharmaceutical sample (4, 10) the solid fraction sensor (17) has a first conductor element (5), a second conductor element (7), an operation space (15) and an energy source (13) arranged to generate an electric field in the operation space (15) by means of the first conductor element (5) and the second conductor element (7), comprising positioning the target pharmaceutical sample (4, 10) in the operation space (15) of the solid fraction sensor (17), determining a capacitance between the first and second conductor element (5, 7) with the target pharmaceutical sample (4, 10) located in the operation space (15), and converting the determined capacitance together with information about a composition of a reference pharmaceutical sample having the essentially same dielectric properties as the target pharmaceutical sample (4, 10) and about a thickness of the reference pharmaceutical sample (4, 10) into a solid fraction of the targe
    Type: Application
    Filed: September 21, 2018
    Publication date: July 9, 2020
    Inventors: Juraj SIBIK, Pascal CHALUS