Patents by Inventor Patricia C. Apel-Birkhold

Patricia C. Apel-Birkhold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8084418
    Abstract: The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from Xenorhabdus, Photorhabdus, and Paenibacillus, can be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a “stand-alone” TC protein (from Photorhabdus, Xenorhabdus, or Paenibacillus, for example) is enhanced by one or more TC protein “potentiators” derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-alone Xenorhabdus protein toxin as well as a stand-alone Photorhabdus protein toxin.
    Type: Grant
    Filed: February 16, 2009
    Date of Patent: December 27, 2011
    Assignee: Dow AgroSciences LLC
    Inventors: Timothy D. Hey, Amanda D. Schleper, Scott A. Bevan, Scott B. Bintrim, Jon C. Michell, Ze Sheng Li, Weiting Ni, Baolong Zhu, Donald J. Merlo, Patricia C. Apel-Birkhold, Thomas Meade
  • Patent number: 7795395
    Abstract: The invention relates to isolated genes encoding Xenorhabdus toxin complex (TC) proteins, and transgenic plants and host cells expressing Xenorhabdus toxin complex (TC) proteins and having resistance to insects.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: September 14, 2010
    Assignee: Dow AgroSciences LLC
    Inventors: Patricia C. Apel-Birkhold, Timothy D. Hey, Joel J. Sheets, Thomas Meade, Ze-Sheng Li, Justin M. Lira, Sean M. Russell, Robin L. Thompson, Jon C. Mitchell, Kristin Fencil
  • Patent number: 7709623
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus strain Xwi. The subject invention also provides an exochitinase obtainable from the Xwi strain. This exochitinase can be used to control insects using methods known in the art.
    Type: Grant
    Filed: April 13, 2009
    Date of Patent: May 4, 2010
    Assignee: Dow AgroSciences LLC
    Inventors: Scott B. Bintrim, Jon C. Mitchell, Ignacio M. Larrinua, Patricia C. Apel-Birkhold, Susan B. Green, Barry W. Schafer, Scott A. Bevan, Scott A. Young, Lining Guo
  • Publication number: 20100004177
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus bovienii strain ILM104.
    Type: Application
    Filed: September 3, 2009
    Publication date: January 7, 2010
    Applicant: Dow AgroSciences LLC
    Inventors: Patricia C. Apel-Birkhold, Timothy Denver Hey, Robin Leola Thompson, Thomas Meade, Ze-Sheng Li, Sean Michael Russell, Joel Jay Sheets, Justin Michael Lira, Kristin Julee Fencil, Jon Christopher Mitchell
  • Patent number: 7585944
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus bovienii strain ILM104.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: September 8, 2009
    Assignee: Dow Agrosciences LLC
    Inventors: Patricia C. Apel-Birkhold, Timothy D. Hey, Joel J. Sheets, Thomas Meade, Ze-Sheng Li, Justin M. Lira, Sean M. Russell, Robin L. Thompson, Jon C. Mitchell, Kristin Fencil
  • Publication number: 20090221501
    Abstract: The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from Xenorhabdus, Photorhabdus, and Paenibacillus, can be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a “stand-alone” TC protein (from Photorhabdus, Xenorhabdus, or Paenibacillus, for example) is enhanced by one or more TC protein “potentiators” derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-alone Xenorhabdus protein toxin as well as a stand-alone Photorhabdus protein toxin.
    Type: Application
    Filed: February 16, 2009
    Publication date: September 3, 2009
    Applicant: Dow AgroSciences LLC
    Inventors: Timothy D. Hey, Amanda D. Schleper, Scott A. Bevan, Scott B. Bintrim, Jon C. Mitchell, Ze Sheng Li, Weiting Ni, Baolong Zhu, Donald J. Merlo, Patricia C. Apel-Birkhold, Thomas Meade
  • Publication number: 20090203612
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus strain Xwi. The subject invention also provides an exochitinase obtainable from the Xwi strain. This exochitinase can be used to control insects using methods known in the art.
    Type: Application
    Filed: April 13, 2009
    Publication date: August 13, 2009
    Applicant: Dow Agrosciences LLC
    Inventors: Scott B. Bintrim, Jon C. Mitchell, Ignacio M. Larrinua, Patricia C. Apel-Birkhold, Susan B. Green, Barry W. Schafer, Scott A. Bevan, Scott A. Young, Lining Guo
  • Patent number: 7517956
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus strain Xwi. The subject invention also provides an exochitinase obtainable from the Xwi strain. This exochitinase can be used to control insects using methods known in the art.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: April 14, 2009
    Assignee: Dow Agrosciences LLC
    Inventors: Scott B. Bintrim, Jon C. Mitchell, Ignacio M. Larrinua, Patricia C. Apel-Birkhold, Susan B. Green, Barry W. Schafer, Scott A. Bevan, Scott A. Young, Lining Guo
  • Patent number: 7491698
    Abstract: The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from Xenorhabdus, Photorhabdus, and Paenibacillus, can be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a “stand-alone” TC protein (from Photorhabdus, Xenorhabdus, or Paenibacillus, for example) is enhanced by one or more TC protein “potentiators” derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-alone Xenorhabdus protein toxin as well as a stand-alone Photorhabdus protein toxin.
    Type: Grant
    Filed: January 7, 2004
    Date of Patent: February 17, 2009
    Assignee: Dow AgroSciences LLC
    Inventors: Timothy D. Hey, Amanda D. Schleper, Scott A. Bevan, Scott B. Bintrim, Jon C. Mitchell, Ze Sheng Li, Weiting Ni, Baolong Zhu, Donald J. Merlo, Patricia C. Apel-Birkhold, Thomas Meade
  • Patent number: 7285632
    Abstract: The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins encoded by genes from Xenorhabdus bovienii strain ILM 104, and methods of controlling an insect with the toxin proteins.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: October 23, 2007
    Assignee: Dow AgroSciences LLC
    Inventors: Patricia C. Apel-Birkhold, Timothy Denver Hey, Robin Leola Thompson, Thomas Meade, Ze-Sheng Li, Sean Michael Russell, Joel Jay Sheets, Justin Michael Lira, Kristin Julee Fencil, Jon Christopher Mitchell
  • Patent number: 7071386
    Abstract: The subject invention relates to novel nucleic acid encoding a Xenorhabdus strain Xwi toxin complex (TC) protein and plants and bacteria transformed therewith.
    Type: Grant
    Filed: January 7, 2004
    Date of Patent: July 4, 2006
    Assignee: Dow Agrosciences LLC
    Inventors: Scott B. Bintrim, Jon C. Mitchell, Ignacio M. Larrinua, Patricia C. Apel-Birkhold, Susan B. Green, Barry W. Schafer, Scott A. Bevan, Scott A. Young, Lining Guo
  • Publication number: 20040208907
    Abstract: The subject invention relates to the surprising discovery that toxin complex (TC) proteins, obtainable from Xenorhabdus, Photorhabdus, and Paenibacillus, can be used interchangeably with each other. In particularly preferred embodiments of the subject invention, the toxicity of a “stand-alone” TC protein (from Photorhabdus, Xenorhabdus, or Paenibacillus, for example) is enhanced by one or more TC protein “potentiators” derived from a source organism of a different genus from which the toxin was derived. As one skilled in the art will recognize with the benefit of this disclosure, this has broad implications and expands the range of utility that individual types of TC proteins will now be recognized to have. Among the most important advantages is that one skilled in the art will now be able to use a single set of potentiators to enhance the activity of a stand-alone Xenorhabdus protein toxin as well as a stand-alone Photorhabdus protein toxin.
    Type: Application
    Filed: January 7, 2004
    Publication date: October 21, 2004
    Applicant: Dow AgroSciences, LLC
    Inventors: Timothy D. Hey, Amanda D. Schleper, Scott A. Bevan, Scott B. Bintrim, Jon C. Mitchell, Ze Sheng Li, Weiting Ni, Baolong Zhu, Donald J. Merlo, Patricia C. Apel-Birkhold, Thomas Meade
  • Publication number: 20040194164
    Abstract: The subject inventions relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifcally, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus strain Xwi. The subject invention also provides an exochitinase obtainable from the Xwi strain. The exochitinase can be used to control insects using methods known in the art.
    Type: Application
    Filed: January 7, 2004
    Publication date: September 30, 2004
    Applicant: Dow AgroSciences, LLC
    Inventors: Scott B. Bintrim, Jon C. Mitchell, Ignacio M. Larrinua, Patricia C. Apel-Birkhold, Susan B. Green, Barry W. Schafer, Scott A. Bevan, Scott A. Young, Lining Guo