Patents by Inventor Patricia Horcajada
Patricia Horcajada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10738068Abstract: The invention relates to nanoparticles made from organometallic hybrid materials made from iron carboxylates, used for example as contrast agents. The particles can also be used for the encapsulation and vectoring of molecules of interest such as active pharmaceutical agents, cosmetically interesting compounds and markers. Apart from the intrinsic properties thereof for imaging, said nanoparticles give good results in terms of capacity of loading with medicaments and in biocompatibility.Type: GrantFiled: July 26, 2018Date of Patent: August 11, 2020Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRSInventors: Patricia Horcajada-Cortes, Gérard Ferey, Christian Serre, Ruxandra Gref, Patrick Couvreur
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Patent number: 10272157Abstract: A process for preparing a porous solid with an outer surface modified by at least one polymer; the polymer being simultaneously synthetized in solution and grafted on the outer surface of the solid, includes contacting: a porous solid; and a polymer-precursor solution comprising an adhesion primer, and at least one polymerizable monomer; under conditions enabling the formation of radical entities.Type: GrantFiled: October 8, 2015Date of Patent: April 30, 2019Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (CEA), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE VERSAILLES SAINT-QUENTIN-EN-YVELINES, UNIVERSITE PARIS-SUD 11Inventors: Thomas Berthelot, Elena Bellido Vera, Ruxandra Gref, Patricia Horcajada Cortes, Christian Serre, Patrick Couvreur
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Patent number: 10159738Abstract: The present invention concerns metal-organic hybrid solids having a modified outer surface. These solids can be used, for example, for the storage and vectoring of molecules of interest such as pharmaceutically active ingredients, compounds of interest in cosmetics and markers, for example contrast agents. These solids have good results in terms of active drug loading capacities, biocompatibility, stability and controlling the release of the active ingredients encapsulated.Type: GrantFiled: May 30, 2013Date of Patent: December 25, 2018Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE DE VERSAILLES-SAINT QUENTIN EN YVELINES, UNIVERSITE PARIS-SUDInventors: Ruxandra Gref, Valentina Agostoni, Samia Daoud-Mahammed, Violeta Rodriguez-Ruiz, Milo Malanga, Laszlo Jicsinszky, Patricia Horcajada-Cortes, Christian Serre
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Publication number: 20180346500Abstract: The invention relates to nanoparticles made from organometallic hybrid materials made from iron carboxylates, used for example as contrast agents. The particles can also be used for the encapsulation and vectoring of molecules of interest such as active3 pharmaceutical agents, cosmetically interesting compounds and markers. Apart from the intrinsic properties thereof for imaging, said nanoparticles give good results in terms of capacity of loading with medicaments and in biocompatibility.Type: ApplicationFiled: July 26, 2018Publication date: December 6, 2018Inventors: Patricia HORCAJADA-CORTES, Gérard FEREY, Christian SERRE, Ruxandra GREF, Patrick COUVREUR
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Patent number: 10065979Abstract: The invention relates to nanoparticles made from organometallic hybrid materials made from iron carboxylates, used for example as contrast agents. The particles can also be used for the encapsulation and vectoring of molecules of interest such as active3 pharmaceutical agents, cosmetically interesting compounds and markers. Apart from the intrinsic properties thereof for imaging, said nanoparticles give good results in terms of capacity for loading with medicaments and in biocompatibility.Type: GrantFiled: October 1, 2008Date of Patent: September 4, 2018Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITÉ DE VERSAILLES—SAINT-QUENTIN-EN-YVELINESInventors: Patricia Horcajada-Cortes, Gérard Ferey, Christian Serre, Ruxandra Gref, Patrick Couvreur
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Publication number: 20160101192Abstract: A process for preparing a porous solid with an outer surface modified by at least one polymer; the polymer being simultaneously synthetized in solution and grafted on the outer surface of the solid, includes contacting: a porous solid; and a polymer-precursor solution comprising an adhesion primer, and at least one polymerizable monomer; under conditions enabling the formation of radical entities.Type: ApplicationFiled: October 8, 2015Publication date: April 14, 2016Inventors: Thomas BERTHELOT, Elena BELLIDO VERA, Ruxandra GREF, Patricia HORCAJADA CORTES, Christian SERRE, Patrick COUVREUR
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Patent number: 9175025Abstract: The present invention relates to a method for preparing a porous organic-inorganic hybrid, which comprises gelling a reaction mixture containing a metal precursor, a water-soluble additive and water or water-containing organic solvent at a gelling temperature of 30° C.˜100° C. to obtain an organogel-containing solution having a viscosity of 2 to 50,000 (cps), subsequently ageing the solution at said gelling temperature under stirring; and subsequently heating the organogel-containing solution at a temperature between said gelling temperature and 250° C. to crystallize the solution.Type: GrantFiled: June 1, 2012Date of Patent: November 3, 2015Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGYInventors: U-Hwang Lee, Jong-San Chang, Young Kyu Hwang, You-Kyong Seo, Christian Serre, Patricia Horcajada Cortes, Hubert Chevreau, Florence Ragon, Thomas Devic
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Publication number: 20150150981Abstract: The present invention concerns metal-organic hybrid solids having a modified outer surface. These solids can be used, for example, for the storage and vectoring of molecules of interest such as pharmaceutically active ingredients, compounds of interest in cosmetics and markers, for example contrast agents. These solids have good results in terms of active drug loading capacities, biocompatibility, stability and controlling the release of the active ingredients encapsulated.Type: ApplicationFiled: May 30, 2013Publication date: June 4, 2015Inventors: Ruxandra Gref, Valentina Agostoni, Samia Daoud-Mahammed, Violeta Rodriguez-Ruiz, Milo Malanga, Laszlo Jicsinszky, Patricia Horcajada-Cortes, Christian Serre
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Patent number: 8926736Abstract: The present invention relates to reducible porous crystalline solids, constituted of a metal-organic framework (MOF), for the separation of mixtures of molecules having different unsaturation degrees and/or a different number of unsaturations with a selectivity that can be adjusted by controlling the reduction of the MOF. The MOF solids of the present invention, after reduction, have a strong affinity for molecules containing at least one unsaturation. They can be used in various separation processes, especially those relating to hydrocarbons.Type: GrantFiled: June 11, 2009Date of Patent: January 6, 2015Assignees: Centre National de la Recherche Scientifique -CNRS-, Universite de Caen-Basse Normandie, Universite de Versailles—Saint Quentin en Yvelines, Korea Research Institute of Chemical & Technology (KRICT)Inventors: Christian Serre, Alexandre Vimont, Philip Llewellyn, Jong-San Chang, Patricia Horcajada-Cortes, Gérard Ferey, Marco Daturi, Young-Kyu Hwang
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Publication number: 20140200361Abstract: The present invention relates to a method for preparing a porous organic-inorganic hybrid, which comprises gelling a reaction mixture containing a metal precursor, a water-soluble additive and water or water-containing organic solvent at a gelling temperature of 30° C.˜100° C. to obtain an organogel-containing solution having a viscosity of 2 to 50,000 (cps), subsequently ageing the solution at said gelling temperature under stirring; and subsequently heating the organogel-containing solution at a temperature between said gelling temperature and 250° C. to crystallize the solution.Type: ApplicationFiled: June 1, 2012Publication date: July 17, 2014Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGYInventors: U-Hwang Lee, Jong-San Chang, Young Kyu Hwang, You-Kyong Seo, Christian Serre, Patricia Horcajada, Hubert Chevreau, Florence Ragon, Thomas Devic
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Publication number: 20120129684Abstract: The present invention relates to the use of solids consisting of a metal-organic framework (MOF) and having the units of the following formula (I): MmOkXILp as a nitrogen-oxide catalyst. The present invention also relates to devices for enabling the implementation of said use. The nitrogen oxides in question are nitrogen monoxide and nitrogen dioxide, collectively referred to as NOx. The MOF solids of the present invention are advantageously capable of removing nitrogen oxides from a liquid or gaseous effluent, for example from water, from the exhaust gases of a vehicle, factory, workshop, laboratory, stored products, urban air vents, etc., without any reducing agent and at a low temperature. The DeNOx catalysis is a major issue for our societies. The invention can be used for reducing or even avoiding the consequences for public health of the toxic NOx gases resulting from human activity.Type: ApplicationFiled: May 28, 2010Publication date: May 24, 2012Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRSInventors: Alexandre Vimont, Patricia Horcajada Cortes, Young Kyu Hwang, Gerard Ferey, Marco Daturi, Jong-San Chang, Christian Serre, Ji Yoon
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Publication number: 20110172412Abstract: The present invention relates to reducible porous crystalline solids, constituted of a metal-organic framework (MOF), for the separation of mixtures of molecules having different unsaturation degrees and/or a different number of unsaturations with a selectivity that can be adjusted by controlling the reduction of the MOF. The MOF solids of the present invention, after reduction, have a strong affinity for molecules containing at least one unsaturation. They can be used in various separation processes, especially those relating to hydrocarbons.Type: ApplicationFiled: June 11, 2009Publication date: July 14, 2011Applicants: Universite De Caen-Basse Normandie, Centre National De La Recherche Scientifique- CNRS-Inventors: Christian Serre, Alexandre Vimont, Philip Llewellyn, Jong-San Chang, Patricia Horcajada-Cortes, Gérard Ferey, Marco Daturi, Young-Kyu Hwang
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Publication number: 20110052650Abstract: The invention relates to solids made of a porous crystalline metal-organic framework (MOF) loaded with at least one gas of biological interest, and to a method for preparing the same. The MOF solids of the present invention are capable of adsorbing and releasing in a controlled manner gases having a biological interest. They can be used in the pharmaceutical field and/or for applications in the cosmetic field. They can also be used in the food industry.Type: ApplicationFiled: March 31, 2009Publication date: March 3, 2011Applicant: Centre National De La Recherche Scientifique - CNR SInventors: Russel Morris, Christian Serre, Patricia Horcajada Cortes, Alexandre Vimont, Thomas Devic, Gérard Ferey
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Publication number: 20100226991Abstract: The invention relates to solid organometallic hybrids with modified surface. Said solid may be used for example for the encapsulation and vectoring of molecules of interest such as active pharmaceutical agents, compounds of interest in cosmetics and markers, for example, contrast agents. Said solids show good results in terms of loading capacity in medicament agents and in biocompatibility.Type: ApplicationFiled: October 1, 2008Publication date: September 9, 2010Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS-, UNIVERSITE DE VERSAILLES - SAINT-QUENTIN-EN- YVELINESInventors: Patricia Horcajada-Cortes, Gérard Ferey, Christian Serre, Ruxandra Gref, Patrick Couvreur
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Publication number: 20100209354Abstract: The invention relates to nanoparticles made from organometallic hybrid materials made from iron carboxylates, used for example as contrast agents. The particles can also be used for the encapsulation and vectoring of molecules of interest such as active3 pharmaceutical agents, cosmetically interesting compounds and markers. Apart from the intrinsic properties thereof for imaging, said nanoparticles give good results in terms of capacity for loading with medicaments and in biocompatibility.Type: ApplicationFiled: October 1, 2008Publication date: August 19, 2010Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, UNIVERSITE DE VERSAILLES - SAINT-QUENTIN- EN-YVELINESInventors: Patricia Horcajada-Cortes, Gérard Ferey, Christian Serre, Ruxandra Gref, Patrick Couvreur