Abstract: A microfluidic system for the validation and study of nanomaterials, drugs, or mixtures thereof for biomedical and/or pharmaceutic applications includes a device for the production of an organoid cell culture having: a base layer for support; a transducer layer arranged on the base layer; and an intermediate layer, arranged on the transducer layer. The intermediate layer has a plurality of cavities for organoid cell growth and a microchannel network for fluid flow, a heating device, and at least a plurality of sensors in each cavity for cell parameter control and growth. Each sensor is located for measuring an organoid cell growth parameter in the interior of each cavity. The heating device is located in the interior of each cavity. The heating device and the plurality of sensors are in direct contact with the organoid cell culture. The plurality of sensors is selected from temperature sensor, pH sensor, heaters or combinations thereof.

Abstract: Various aspects of this disclosure provide systems and methods for managing vehicle on-board diagnostic (OBD) data in a network of moving things. As non-limiting examples, various aspects of this disclosure provide systems and methods for interfacing with vehicle OBD systems, acquiring OBD data, communicating OBD data, and/or processing OBD data in a network of moving things, for example including OBD data of autonomous vehicles and other vehicles.

Abstract: Various aspects of this disclosure provide systems and methods for managing vehicle on-board diagnostic (OBD) data in a network of moving things. As non-limiting examples, various aspects of this disclosure provide systems and methods for interfacing with vehicle OBD systems, acquiring OBD data, communicating OBD data, and/or processing OBD data in a network of moving things, for example including OBD data of autonomous vehicles and other vehicles.

Abstract: The present invention deals with a composition for evidencing bacterial plaque based on natural colorants comprising at least one concentrated solution of natural colorant selected from the group consisting of colorants extracted from the aai (Euterpe oleracea) and colorants extracted from urucum (Bixa orellana), in a pharmaceutically acceptable vehicle and, optionally, acceptable pharmaceutical additives. Preferentially, in the case of the aai solution, the concentration varies from 60 to 95% of concentrated extract, whilst for the urucum solution, the concentration varies between 56 and 90% of concentrated extract. Also preferentially, in solutions containing a mixture of the extracts, these will be present in a proportion that varies from 10:1 to 1:1.

Abstract: The present invention deals with a composition for evidencing bacterial plaque based on natural colorants comprising at least one concentrated solution of natural colorant selected from the group consisting of colorants extracted from the aai (Euterpe oleracea) and colorants extracted from urucum (Bixa orellana), in a pharmaceutically acceptable vehicle and, optionally, acceptable pharmaceutical additives. Preferentially, in the case of the aai solution, the concentration varies from 60 to 95% of concentrated extract, whilst for the urucum solution, the concentration varies between 56 and 90% of concentrated extract.