Patents by Inventor Paul D. May

Paul D. May has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing indolinone derivatives
    Patent number: 7119209
    Abstract: The present invention refers to a process for preparing indolinone derivatives of the general formula (VI) as defined in the specification and intermediates of that process.
    Type: Grant
    Filed: February 14, 2003
    Date of Patent: October 10, 2006
    Assignee: Pharmacia & Upjohn Company
    Inventors: Qingwu Jin, Michael A. Mauragis, Paul D. May
  • Heterocycle carboxamides as antiviral agents
    Publication number: 20040142928
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: December 23, 2003
    Publication date: July 22, 2004
    Inventors: Gordon L. Bundy, Fred L. Ciske, Michael J. Genin, Steven E. Heasley, Scott D. Larsen, Byung Hyun Lee, Paul D. May, John R. Palmer, Mark E. Schnute, Valerie A. Vaillancourt, Atli Thorarensen, Allison J. Wolf, Nancy Anne Wicnienski, David Wilhite
  • Process for preparing indolinone derivatives
    Publication number: 20030229229
    Abstract: The present invention refers to a process for preparing indolinone derivatives of the general formula (VI) as defined in the specification and intermediates of that process.
    Type: Application
    Filed: February 14, 2003
    Publication date: December 11, 2003
    Inventors: Qingwu Jin, Michael A. Mauragis, Paul D. May
  • Heterocycle carboxamides as antiviral agents
    Publication number: 20030207880
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: December 18, 2002
    Publication date: November 6, 2003
    Inventors: Gordon L. Bundy, Fred L. Ciske, Michael J. Genin, Steven E. Heasley, Scott D. Larsen, Byung Hyun Lee, Paul D. May, John R. Palmer, Mark E. Schnute, Valerie A. Vaillancourt, Atli Thorarensen, Allison J. Wolf, Nancy Anne Wicnienski, David Wilhite
  • Aminoguanidine carboxylates for the treatment of non-insulin-dependent diabetes mellitus
    Publication number: 20020082448
    Abstract: The present invention provide for a method of reducing blood glucose levels in a patient by administering an effective amount of a compound of the formula III or a pharmaceutically acceptable salt thereof; 1
    Type: Application
    Filed: July 13, 2001
    Publication date: June 27, 2002
    Applicant: The Upjohn Company
    Inventors: Scott D. Larsen, Valerie A. Vaillancourt, Paul D. May, Steven P. Tanis, John A. Tucker, Martin D. Meglasson, Heinrich J. Schostarez
  • Inhibitors of protein tyrosine phosphatase
    Patent number: 6410585
    Abstract: The present invention comprises small molecular weight, non-peptidic inhibitors of formulae I-VII of Protein Tyrosine Phosphatase 1 (PTP1) which are useful for the treatment and/or prevention of Non-Insulin Dependent Diabetes Mellitus (NIDDM).
    Type: Grant
    Filed: March 10, 1999
    Date of Patent: June 25, 2002
    Inventors: Scott D. Larsen, Paul D. May, John E. Bleasdale, Charlotta Liljebris, Heinrich Josef Schostarez, Tjeerd Barf, Marianne Nilsson
  • Inhibitors of protein tyrosine phosphatase
    Patent number: 6353023
    Abstract: The present invention comprises small molecular weight, non-peptidic inhibitors of formula I and II of Protein Tyrosine Phosphatase 1 (PTP1) which are useful for the treatment and/or prevention of Non-Insulin Dependent Diabetes Mellitus (NIDDM).
    Type: Grant
    Filed: August 24, 1998
    Date of Patent: March 5, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Scott D. Larsen, Paul D. May, John E. Bleasdale, Charlotta Liljebris, Heinrich Josef Schostarez, Tjeerd Barf
  • Heterocycle carboxamides as antiviral agents
    Publication number: 20020025960
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: June 22, 2001
    Publication date: February 28, 2002
    Inventors: Gordon L. Bundy, Fred L. Ciske, Michael J. Genin, Steven E. Heasley, Scott D. Larsen, Byung Hyun Lee, Paul D. May, John R. Palmer, Mark E. Schnute, Valerie A. Vaillancourt, Atli Thorarensen, Allison J. Wolf, Nancy Anne Wicnienski, David Wilhite
  • Aminoguanidine carboxylates for the treatment of non-insulin-dependent diabetes mellitus
    Patent number: 6329545
    Abstract: The present invention provides novel compounds of the formula I and II for the treatment of non-insulin dependent diabetes mellitius (NIDDM) and a new use of known compounds for this purpose.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: December 11, 2001
    Inventors: Scott D. Larsen, Valerie A. Vaillancourt, Paul D. May, Steven P. Tanis, John A. Tucker, Martin D. Meglasson, Heinrich J. Schostarez
  • Aminoguanidine carboxylate lactams for the treatment of non-insulin-dependent diabetes mellitus
    Patent number: 6274580
    Abstract: Compounds selected from the group consisting of formulae I, II, III, IV, VI, VII, and VIII wherein R is H or NH2, and pharmacologically acceptable salts thereof, are suitable for use in methods for treating non-insulin-dependent diabetes mellitus (NIDDM) or obesity in a patient susceptible to or experiencing NIDDM or obesity by the systemic administration of such a compound in an amount effective to treat the NIDDM or obesity.
    Type: Grant
    Filed: August 29, 2000
    Date of Patent: August 14, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Scott D. Larsen, Martin D. Meglasson, Valerie A. Vaillancourt, Paul D. May
  • Aminoguanidine carboxylate lactams for the treatment of non-insulin-dependent diabetes mellitus
    Patent number: 6184216
    Abstract: Compounds selected from the group consisting of formulae III, IV, VI and VIII wherein R is H is NH2, or a pharmacologically acceptable salt thereof, are suitable for use in methods for treating non-insulin-dependent diabetes mellitus (NIDDM) or obesity in a patient susceptible to or experiencing NIDDM or obesity by the systemic administration of such a compound in an amount effective to treat the NIDDM or obesity.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: February 6, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Scott D. Larsen, Martin D. Meglasson, Valerie A. Vaillancourt, Paul D. May
  • Aminoguanidine carboxylate lactams for the treatment of non-insulin-dependent diabetes mellitus
    Patent number: 6177453
    Abstract: The present invention provides for the treatment of non-insulin dependent diabetes mellitus or obesity comprising the systemic administration of a compound having the formula or a pharmacologically acceptable salt thereof, wherein each R is H or NH2, and with the proviso that at least one R group must be NH2.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: January 23, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Scott D. Larsen, Martin D. Meglasson, Valerie A. Vaillancourt, Paul D. May
  • Aminoquanidine carboxylates for the treatment of obesity
    Patent number: 6166080
    Abstract: The present invention provides novel compounds of the formulae (I): AG--(CH.sub.2).sub.n --CO.sub.2 R.sup.1 and (II) or pharmacologically acceptable salts thereof, wherein AG is: a) N-aminoguanidine, b) N,N'-diaminoguanidine, or c) N,N',N"-triaminoguanidine; and n, R.sup.1 and R.sup.2 have the meanings given in the description as well as a new use for the compounds of formula (III) wherein R.sup.3 has the meanings given in the description for the treatment of non-insulin dependent diabetes mellitus (NIDDM).
    Type: Grant
    Filed: May 22, 1997
    Date of Patent: December 26, 2000
    Assignee: Pharmacia
    Inventors: Scott D. Larsen, Paul D. May, Steven P. Tanis, Valerie A. Vaillancourt, John A. Tucker, Heinrich J. Schostarez, Martin D. Meglasson
  • Aminoguanidine carboxylates for the treatment of non-insulin-dependent diabetes mellitus
    Patent number: 5994577
    Abstract: The present invention provides novel compounds of the formula I and II for the treatment of non-insulin dependent diabetes mellitius (NIDDM) and a new use of known compounds for this purpose.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 30, 1999
    Inventors: Scott D. Larsen, Valerie A. Vaillancourt, Paul D. May, Steven P. Tanis, John A. Tucker, Martin D. Meglasson, Heinrich J. Schostarez
  • Aminoguanidine carboxylate lactams for the treatment of non-insulin-dependent diabetes mellitus
    Patent number: 5955617
    Abstract: The present invention provides novel compounds of the formulae I-VIII for the treatment of non-insulin dependent diabetes mellitus (NIDDM) and a new use of known compounds IX to X for this purpose.
    Type: Grant
    Filed: May 15, 1997
    Date of Patent: September 21, 1999
    Assignee: Pharmacia & Upjohn Company
    Inventors: Scott D. Larsen, Martin D. Meglasson, Valerie A. Vaillancourt, Paul D. May
  • Alkyl substituted piperadinyl and piperazinyl anti-AIDS compounds
    Patent number: 5866589
    Abstract: Anti-AIDS compounds of formula (I) ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 are as defined in the specification and R.sub.8 is alkyl of substituted alkyl.
    Type: Grant
    Filed: June 9, 1997
    Date of Patent: February 2, 1999
    Assignee: Pharmacia & Upjohn Company
    Inventors: Donna L. Romero, Richard C. Thomas, Paul D. May, Toni-Jo Poel
  • Platelet activating factor antagonists
    Patent number: 5382670
    Abstract: Indole compounds substituted at the 1- or 3-position by a (pyrid-3-yl)thiazolid-4-yl)alkyl-, (pyrid-3-yl)thiazolid-4-oyl)-, (pyrid-3-yl)dithiolan-4-yl)alkyl- or (pyrid-3-yl)dithiolan-4-oyl)- group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including septic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation.
    Type: Grant
    Filed: July 7, 1993
    Date of Patent: January 17, 1995
    Assignee: Abbott Laboratories
    Inventors: James B. Summers, George S. Sheppard, James G. Phillips, Daisy Pireh, Douglas H. Steinman, Paul D. May, Denise E. Guinn, H. Robin Heyman, George M. Carrera, Jr., Steven K. Davidsen
  • Peptide analog type-B CCK receptor ligands
    Patent number: 5340802
    Abstract: Peptide analog type-B CCK receptor ligands or pharmaceutically-acceptable salts thereof, which are useful for treating central nervous system disorders, substance abuse, gastrointestinal disorders, endocrine disorders, eating-related disorders and for the treatment of shock, respiratory and cardiocirculatory insufficiencies.
    Type: Grant
    Filed: January 29, 1993
    Date of Patent: August 23, 1994
    Assignee: Abbott Laboratories
    Inventors: Kazumi Shiosaki, Alex M. Nadzan, David S. Garvey, Youe-Kong Shue, Mark S. Brodie, Mark W. Holladay, John Y.-L. Chung, Michael D. Tufano, Paul D. May
  • Benzoylphenyl pyridinylthiazolidine compounds as platelet activating antagonists
    Patent number: 5120751
    Abstract: Benzoylphenyl derivatives of 2-(3-pyridinyl)-3-alkyl-4-thiazolidinecarboxamide, 2-(3-pyridinyl)-thiazolid-4-ylacetamide, 2-(3-pyridinyl)-4-dithiolanecarboxamide or 2-(3-pyridinyl)dithiolan-4-yl] urea are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including anaphylactic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation.
    Type: Grant
    Filed: March 29, 1991
    Date of Patent: June 9, 1992
    Assignee: Abbott Laboratories
    Inventors: James B. Summers, Douglas H. Steinman, Denise E. Guinn, Steven K. Davidsen, Paul D. May
  • Platelet activating antagonists
    Patent number: 5120749
    Abstract: Indole compounds substituted at the 1- or 3 position by a (pyrid-3 yl)thiazolid-4-yl)alkyl-, (pyrid-3-yl)thiazolid-4-oyl)-, (pyrid-3-yl)dithiolan-4-yl)alkyl- or (pyrid-3-yl) dithiolan-4-ol)- group are potent inhibitors of PAF and are useful in the treatment of PAF-related disorders including anaphylactic shock, respiratory distress syndrome, acute inflammation, delayed cellular immunity, parturtition, fetal lung maturation, and cellular differentiation.
    Type: Grant
    Filed: February 20, 1991
    Date of Patent: June 9, 1992
    Assignee: Abbott Laboratories
    Inventors: James B. Summers, George S. Sheppard, James G. Phillips, Daisy Pireh, Douglas H. Steinman, Paul D. May