Patents by Inventor Paul E. Kelley

Paul E. Kelley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5134286
    Abstract: A mass spectrometry method in which notch-filtered noise is applied to an ion trap to resonate all ions except selected ions out of the region of the trapping field. Preferably, the trapping field is a quadrupole trapping field defined by a ring electrode and a pair of end electrodes positioned symmetrically along a z-axis, and the filtered noise is applied to the ring electrode to eject unwanted ions in radial directions rather than toward a detector mounted along the z-axis. Also preferably, the trapping field has a DC component selected so that the trapping field has both a high frequency and low frequency cutoff, and is incapable of trapping ions with resonant frequency below the low frequency cutoff or above the high frequency cutoff. Application of the filtered noise signal to such a trapping field is functionally equivalent to filtration of the trapped ions through a notched bandpass filter having such high and low frequency cutoffs.
    Type: Grant
    Filed: February 28, 1991
    Date of Patent: July 28, 1992
    Assignee: Teledyne CME
    Inventor: Paul E. Kelley
  • Patent number: 5105081
    Abstract: A mass spectrometry method and apparatus in which trapped ions of interest are detected as they strike a detector comprising at least one of the electrodes which establish the ion trapping field. The invention eliminates the need to eject ions from the trap, and thus eliminates the need to perforate one or more of the trap electrodes. In one class of preferred embodiments, the trapping field is a three-dimensional quadrupole trapping field within a region bounded by a ring electrode and a pair of end electrodes. In one embodiment, the inventive in-trap detector is a trap electrode composed (or partially composed) of phosphorescent material which emits photons in response to incidence of ions at its inward-facing surface (the surface of the electrode which faces the trap region). In another embodiment, the in-trap ion detector is a Faraday effect detector which includes an electrically isolated conductive pin mounted with its tip flush with the inward-facing surface of one of the trap electrodes.
    Type: Grant
    Filed: February 28, 1991
    Date of Patent: April 14, 1992
    Assignee: Teledyne CME
    Inventor: Paul E. Kelley
  • Patent number: 4749860
    Abstract: Method of isolating ions of selected mass in a quadrupole ion trap of the type including a ring electrode and end caps in which RF and AC voltages are applied to the ring electrode and end caps and scanned to trap a single ion of interest.
    Type: Grant
    Filed: June 5, 1986
    Date of Patent: June 7, 1988
    Assignee: Finnigan Corporation
    Inventors: Paul E. Kelley, George C. Stafford, Jr., John E. P. Syka
  • Patent number: 4736101
    Abstract: A simple and economical method of mass analyzing a sample by means of a quadrupole ion trap mass spectrometer in an MS/MS mode comprises the steps of forming ions within a trap structure, changing the RF and DC voltages in such a way that the ions with mass-to-charge ratios within a desired range will be and remain trapped within the trap structure, dissociating such ions into fragments by collisions and increasing the field intensity again so that the generated fragments will become unstable and exit the trap volume sequentially to be detected. A supplementary AC field may be applied additionally to provide various scan modes as well as dissociate the ions.
    Type: Grant
    Filed: August 11, 1987
    Date of Patent: April 5, 1988
    Assignee: Finnigan Corporation
    Inventors: John E. P. Syka, John N. Louris, Paul E. Kelley, George C. Stafford, Walter E. Reynolds
  • Patent number: 4686367
    Abstract: The method of performing chemical ionization and mass analysis with a quadrupole ion trap.
    Type: Grant
    Filed: September 6, 1985
    Date of Patent: August 11, 1987
    Assignee: Finnigan Corporation
    Inventors: John N. Louris, John E. P. Syka, Paul E. Kelley
  • Patent number: 4650999
    Abstract: The method of operating a quadrupole ion trap in which the mass range of interest is analyzed in segments by trapping ions of successive mass ranges within the segments whereby the operating parameters for each segment may be selected to improve sensitivity and resolution.
    Type: Grant
    Filed: October 22, 1984
    Date of Patent: March 17, 1987
    Assignee: Finnigan Corporation
    Inventors: William J. Fies, Jr., Paul E. Kelley, Walter E. Reynolds, George C. Stafford, Jr., John E. P. Syka
  • Patent number: 4540884
    Abstract: In a quadrupole ion store or ion trap type mass spectometer, significantly improved mass selection is achieved by simultaneously trapping ions within the mass range of interest and then scanning the applied RF and DC voltages or the frequency .omega. to sequentially render unstable trapped ions of consecutive specific masses. These are passed out through apertures in an end cap to a high gain electron multiplier to provide a signal indicative of the ion mass. Sensitivity and mass resolution is also enhanced by operating the ion trap at a relatively high pressure in the range 1.times.10.sup.-1 to 1.times.10.sup.-5 torr. The presence of collision gas molecules, such as helium, improves sensitivity and mass resolution. In addition, the structure itself is built of stacked units, sealed by O-rings, which are easily disassembled for cleaning.
    Type: Grant
    Filed: December 29, 1982
    Date of Patent: September 10, 1985
    Assignee: Finnigan Corporation
    Inventors: George C. Stafford, Paul E. Kelley, David R. Stephens
  • Patent number: RE34000
    Abstract: A simple and economical method of mass analyzing a sample by means of a quadrupole ion trap mass spectrometer in an MS/MS mode comprises the steps of forming ions within a trap structure, changing the RF and DC voltages in such a way that the ions with mass-to-charge ratios within a desired range will be and remain trapped within the trap structure, dissociating such ions into fragments by collisions and increasing the field intensity again so that the generated fragments will become unstable and exit the trap volume sequentially to be detected. A supplementary AC field may be applied additionally to provide various scan modes as well as dissociate the ions.
    Type: Grant
    Filed: March 27, 1990
    Date of Patent: July 21, 1992
    Assignee: Finnigan Corporation
    Inventors: John E. P. Syka, John N. Louris, Paul E. Kelley, George C. Stafford, Walter E. Reynolds