Abstract: Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, engaging an interventional device of a catheter system with clot material in a blood vessel and withdrawing the interventional device and the portion of the clot material through a guide catheter. In some embodiments, the catheter system can include an attachment/valve member coupled to a proximal portion of the guide catheter, and the method can include unsealing the attachment/valve member to facilitate withdrawing the interventional device through the attachment/valve member without significant retention of clot material within the attachment/valve member. The method can further include resealing and aspirating the guide catheter before advancing another interventional device to the clot material to again engage and remove clot material from the blood vessel.

Abstract: A speaker can have a main body with a generally spheroidal shape, which can be supported standing on its end. The speaker can include a subwoofer that faces forward. A plurality of mid-range drivers can be distributed around the sub-woofer, facing generally forward and radially outward. A plurality of tweeters can be distributed around the sub-woofer, facing generally forward and generally outward. The outer housing portion of the speaker can be covered with a fabric material. A user interface ring 162 can be touch sensitive to receive input, and can have a plurality of lights that can be illuminated separately to convey information to the user.

Abstract: A drug delivery device for delivering a medicament includes a pump first housing, a pump second housing, an inlet fluid path, and an outlet fluid path. The pump first housing is at least partially supporting and/or surrounding a fluid displacement assembly. The pump second housing is at least partially supporting and/or surrounding a drive component for driving the fluid displacement assembly. The inlet fluid path is configured to deliver medicament to the fluid displacement assembly. The outlet fluid path is configured to receive medicament from the fluid displacement assembly. The pump first housing and the pump second housing are removably coupled with each other.

Abstract: The present disclosure relates to compounds that act as inhibitors of NLRP3 inflammasomes; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with inflammation and inflammaging, including hearing loss and other diseases associated with aging.

Abstract: A system is provided for automatically generating electronic artifacts using extended functionality. In particular, the system may use a template-based process to automatically generate artifacts based on a defined set of parameters and/or variables. The system may further use one or more plugins which may provide extended functionality with respect to the artifact generation process. Accordingly, the artifact generation process may include initializing a parameter list based on application parameters and/or plugin parameters, processing the parameters, generating variables based on the parameters, and replacing variables in scheme template files with appropriate values (e.g., user supplied or plugin generated values) to output an artifact file to a predetermined location. In this way, the system provides a robust and efficient way to automatically generate artifacts.

Abstract: A water testing and measuring system is disclosed including a water generator configured to generate water by extracting water vapor from ambient air. A compound generator is configured to apply a compound to the water generated by the water generator. A processor is in communication with the water generator and the compound generator. A measurement device is in communication with the water generator, the compound generator and the processor.

Abstract: Technologies and implementations for a defibrillator electrode having communicative capabilities are generally disclosed.

Abstract: Described herein are neurotrophic and nootropic compositions and methods for treating subjects with such compositions. In one aspect the composition comprises one or more tryptamines or in pure form or extracts from psilocybin containing mushrooms, or combinations thereof optionally combined with one or more phenethylamines or amphetamines in pure form or extracts from a plant or mushroom, or combinations thereof, optionally one or more erinacines or hericenones in pure form, extracts from Hericium mushroom species (e.g., H. erinaceus, H. coralloides, H. ramosum) or combinations thereof, optionally one or more cannabinoids in pure form or extracts from Cannabis sativa, Cannabis sativa, Cannabis indica, or Cannabis ruderalis, optionally, one or more adversive compounds, and optionally one or more pharmaceutically acceptable excipients.

Abstract: A method for producing polymeric microparticle compositions using the steps of: 1) melt processing an immiscible polymeric blend comprising an immiscible polymer matrix and a soluble polymer matrix, 2) dissolving the soluble polymer matrix of the immiscible polymeric blend using a solvent to yield a polymeric microparticle composition, and 3) isolating the polymeric microparticle composition.

Abstract: Examples provide a door assembly including a dual operation slide device for a sliding privacy door associated with a seat unit. The door assembly includes a sliding door movably mounted to a door support member of a seat unit. The door slides laterally between a retracted position and a deployed or partially deployed position. The dual operation slide device includes a trigger and release mechanism for switching the door assembly from a primary track system used during a normal operation mode to a secondary track system used during a backup operation mode if the primary track becomes jammed or otherwise malfunctions based on manual activation of a release lever or force applied activation. The dual operation slide device enables a user to return the sliding door to a retracted position after a failure of the primary slide units to operate in the normal operational mode.

Abstract: Aspects of the subject disclosure may include, for example, determining a requirement of a network-accessible service requested by a user, and determining a network policy according to the service. An infrastructure of a network domain is organized according to the requirement and the policy to provide the service. A distributed controller operating within the network domain configures time-insensitive and time sensitive network domain functions according to the network policy. The time-insensitive functions are obtained from the distributed controller and applied in a manner that selects an access domain type of a number of different types. The selection is made according to an application of the time-insensitive and time sensitive network domain functions. Network performance data is monitored, and the infrastructure is reconfigured responsive to the application the functions, to obtain a reconfigured network infrastructure based on the network performance data, to ensure compliance with the network policy.

Abstract: Described herein are neurotrophic and nootropic compositions and methods for treating subjects with such compositions. In one aspect the composition comprises one or more tryptamines or in pure form or extracts from psilocybin containing mushrooms, or combinations thereof optionally combined with one or more phenethylamines or amphetamines in pure form or extracts from a plant or mushroom, or combinations thereof, optionally one or more erinacines or hericenones in pure form, extracts from Hericium mushroom species (e.g., H. erinaceus, H. coralloides, H. ramosum) or combinations thereof, optionally one or more cannabinoids in pure form or extracts from Cannabis sativa, Cannabis sativa, Cannabis indica, or Cannabis ruderalis, optionally, one or more adversive compounds, and optionally one or more pharmaceutically acceptable excipients.

Abstract: A device implementing a real time clock integrated module for outputting data indicating a time-of-day. The real time clock integrated module includes: a high-precision oscillator or atomic clock having an accuracy of 50 ppb (parts per billion) or better; a timing circuit for generating time-of-day data according to a clock signal outputted from the oscillator or atomic clock; a power source allowing the timing circuit to maintain time when the device is powered off. The timing circuit includes a real time clock and a logic device storing a timestamp. The timing circuit is configured when the device is powered off to update the timestamp value based on the oscillator or atomic clock and to generate a time reference signal and to provide to the device the updated timestamp value and the time reference signal that the device can use as a time reference once the device is powered up again.

Abstract: A reinforcement learning receiver front-end (RL-RXFE) is disclosed having a low-noise amplifier (LNA) with adjustable supply voltage and adjustable bias voltages, a frequency selective limiter (FSL) coupled to the LNA and configured to attenuate undesired radio frequency (RF) bands and for sensing RF band power, and a combination of an analog-to-digital converter configured to convert an RF signal amplified by the LNA to a digital signal, a digital signal processor configured to generate spectrum information from the digital signal, and a baseband distortion by-product detector/sensor configured to generate distortion by-product information, and LNA dynamic information. A reinforcement learning processing circuitry receives and uses this information to perform reinforcement learning and to output control signals to the FSL and the LNA to maximize linearity and efficiency.

Abstract: The present invention relates to a roller for use in an agricultural or mowing machine, the roller comprising a pair of tapered roller bearings and a pair of roller bearings, wherein the tapered roller bearings are closer to the midpoint of the roller than the roller bearings. An agricultural or mowing machine comprising the roller is also described.

Abstract: A networked HVAC system is implemented as part of a multi-unit dwelling. At least one HVAC unit is installed within each unit of the multi-unit dwelling. Each individual HVAC unit includes a localized HVAC unit controller, which is connected to an external network. The HVAC unit controller also can be connected to any other controllable HVAC devices in the unit, such as an exhaust fan. The HVAC system addresses the open-loop issue by monitoring temperature, air flow, humidity, air pressure, occupancy, window open/close state, and HVAC units of all units in a multi-unit dwelling, as well as common areas, and optimizing operating parameters to minimize wide swings in operational states and managing the overall system of multiple units/common areas so that energy usage and temperature/ventilation control is optimized. The HVAC system also enables learning and predictive modeling for adapting to real-time and anticipated condition requirements within each zone.

Abstract: Systems, method and computer readable medium are provided for automated storage and retrieval. User authentication information is received via a user interface for a dynamic storage and retrieval device. The user identity is verified based upon the authentication information and previously stored authentication data. Order information is retrieved for an order associated with the user following the verifying of user identity, the order information indicating one or more locations for items associated with the order. Instructions are transmitted to initiate a physical opening of at least one of the dynamic storage and retrieval device and at least one static storage location to enable the user to retrieve at least one item of the order, the static storage location including a controller controlling a locking mechanism and communicatively coupled to the dynamic storage and retrieval device.

Abstract: A cable hanger including a body defining a support coupling and a number of supported element couplings. The support coupling is a rigid element support coupling.

Abstract: The disclosure relates to a method for detecting a nerve agent in an analyte, said nerve agent having a phosphorus-fluorine bond, which method comprises: (a) contacting the analyte with a solid state composition comprising a sensor compound; wherein the sensor compound comprises a basic nitrogen atom and a hydroxyaryl moiety protected by a silyl protecting group; and wherein, in the presence of hydrogen fluoride, said silyl group is cleaved to effect deprotection of the hydroxyl group thus forming a luminescent reporter compound; (b) irradiating the solid state composition at a predetermined wavelength; (c) measuring the luminescence to determine if the reporter compound is present; and (d) determining whether the nerve agent is present in the analyte based on the measurement obtained in step (c).