Patents by Inventor Paul J. Vernucci
Paul J. Vernucci has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11284616Abstract: A blood storage system comprising: a collection vessel for red blood cells; an oxygen or oxygen and carbon dioxide depletion device; a storage vessel for red blood cells; tubing connecting the collection vessel to the oxygen or oxygen and carbon dioxide depletion device and the oxygen or oxygen and carbon dioxide depletion device to the storage vessel; and a gamma or X-ray irradiating device is used to irradiate red blood cells stored in the vessel, storing red blood cells under anaerobic conditions.Type: GrantFiled: October 10, 2018Date of Patent: March 29, 2022Assignee: Hemanext Inc.Inventors: Tatsuro Yoshida, Paul J. Vernucci
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Publication number: 20190037834Abstract: A blood storage system comprising: a collection vessel for red blood cells; an oxygen or oxygen and carbon dioxide depletion device; a storage vessel for red blood cells; tubing connecting the collection vessel to the oxygen or oxygen and carbon dioxide depletion device and the oxygen or oxygen and carbon dioxide depletion device to the storage vessel; and a gamma or X-ray irradiating device is used to irradiate red blood cells stored in the vessel, storing red blood cells under anaerobic conditions.Type: ApplicationFiled: October 10, 2018Publication date: February 7, 2019Applicant: New Health Sciences, Inc.Inventors: Tatsuro Yoshida, Paul J. Vernucci
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Patent number: 10136635Abstract: A blood storage system comprising: a collection vessel for red blood cells; an oxygen or oxygen and carbon dioxide depletion device; a storage vessel for red blood cells; tubing connecting the collection vessel to the oxygen or oxygen and carbon dioxide depletion device and the oxygen or oxygen and carbon dioxide depletion device to the storage vessel; and a gamma or X-ray irradiating device is used to irradiate red blood cells stored in the vessel, storing red blood cells under anaerobic conditions.Type: GrantFiled: November 4, 2011Date of Patent: November 27, 2018Assignee: New Health Sciences, Inc.Inventors: Tatsuro Yoshida, Paul J. Vernucci
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Patent number: 10065134Abstract: A blood filter device comprising: a housing comprising an outer wall and a first inlet, a first outlet and a second outlet; a membrane which is capable of separating plasma from the blood, wherein the membrane forms an inner chamber; a leukocyte and oxygen and/or carbon dioxide depletion media disposed wherein the inner chamber, the leukocyte and oxygen and/or carbon dioxide depletion media is capable of depleting leukocytes and oxygen and/or carbon dioxide from the blood; an outer chamber disposed between the outer wall and the membrane, wherein the plasma which permeates through the membrane enters the outer chamber and exits the filter device via the first outlet; whereby the blood which has been depleted of oxygen and/or carbon dioxide, leukocytes and plasma exists and filter device via the second outlet.Type: GrantFiled: November 29, 2016Date of Patent: September 4, 2018Assignee: New Health Sciences, Inc.Inventors: Tatsuro Yoshida, Paul J. Vernucci
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Publication number: 20170072339Abstract: A blood filter device comprising: a housing comprising an outer wall and a first inlet, a first outlet and a second outlet; a membrane which is capable of separating plasma from the blood, wherein the membrane forms an inner chamber; a leukocyte and oxygen and/or carbon dioxide depletion media disposed wherein the inner chamber, the leukocyte and oxygen and/or carbon dioxide depletion media is capable of depleting leukocytes and oxygen and/or carbon dioxide from the blood; an outer chamber disposed between the outer wall and the membrane, wherein the plasma which permeates through the membrane enters the outer chamber and exits the filter device via the first outlet; whereby the blood which has been depleted of oxygen and/or carbon dioxide, leukocytes and plasma exists and filter device via the second outlet.Type: ApplicationFiled: November 29, 2016Publication date: March 16, 2017Applicant: New Health Sciences, Inc.Inventors: Tatsuro YOSHIDA, Paul J. VERNUCCI
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Patent number: 9539375Abstract: A blood filter device comprising: a housing comprising an outer wall and a first inlet, a first outlet and a second outlet; a membrane which is capable of separating plasma from the blood, wherein the membrane forms an inner chamber; a leukocyte and oxygen and/or carbon dioxide depletion media disposed wherein the inner chamber, the leukocyte and oxygen and/or carbon dioxide depletion media is capable of depleting leukocytes and oxygen and/or carbon dioxide from the blood; an outer chamber disposed between the outer wall and the membrane, wherein the plasma which permeates through the membrane enters the outer chamber and exits the filter device via the first outlet; whereby the blood which has been depleted of oxygen and/or carbon dioxide, leukocytes and plasma exists and filter device via the second outlet.Type: GrantFiled: March 2, 2015Date of Patent: January 10, 2017Assignee: New Health Sciences, Inc.Inventors: Tatsuro Yoshida, Paul J. Vernucci
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Patent number: 9296990Abstract: An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.Type: GrantFiled: September 26, 2013Date of Patent: March 29, 2016Assignees: New Health Sciences, Inc., University of Pittsburgh-of the Commonwealth System of Higher EducationInventors: William J. Federspiel, Brian J. Frankowski, Tatsuro Yoshida, Paul J. Vernucci
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BLOOD STORAGE BAG SYSTEM AND DEPLETION DEVICES WITH OXYGEN AND CARBON DIOXIDE DEPLETION CAPABILITIES
Publication number: 20150284682Abstract: A blood storage system. The system has a collection bag for red blood cells; an oxygen/carbon dioxide depletion device; a storage bag for red blood cells; and tubing connecting the collection bag to the depletion device and the depletion device to the storage bag. The depletion device includes a receptacle of a solid material having an inlet and an outlet adapted to receiving and expelling a flushing gas; a plurality of hollow fibers or gas-permeable films extending within the receptacle from an entrance to an exit thereof. The hollow fibers or gas-permeable films are adapted to receiving and conveying red blood cells.Type: ApplicationFiled: June 22, 2015Publication date: October 8, 2015Applicant: NEW HEALTH SCIENCES, INC.Inventors: Tatsuro YOSHIDA, Paul J. VERNUCCI -
Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities
Patent number: 9095662Abstract: A blood storage system. The system has a collection bag for red blood cells; an oxygen/carbon dioxide depletion device; a storage bag for red blood cells; and tubing connecting the collection bag to the depletion device and the depletion device to the storage bag. The depletion device includes a receptacle of a solid material having an inlet and an outlet adapted to receiving and expelling a flushing gas; a plurality of hollow fibers or gas-permeable films extending within the receptacle from an entrance to an exit thereof. The hollow fibers or gas-permeable films are adapted to receiving and conveying red blood cells.Type: GrantFiled: August 16, 2013Date of Patent: August 4, 2015Assignee: New Health Sciences, Inc.Inventors: Tatsuro Yoshida, Paul J Vernucci -
Publication number: 20150165102Abstract: A blood filter device comprising: a housing comprising an outer wall and a first inlet, a first outlet and a second outlet; a membrane which is capable of separating plasma from the blood, wherein the membrane forms an inner chamber; a leukocyte and oxygen and/or carbon dioxide depletion media disposed wherein the inner chamber, the leukocyte and oxygen and/or carbon dioxide depletion media is capable of depleting leukocytes and oxygen and/or carbon dioxide from the blood; an outer chamber disposed between the outer wall and the membrane, wherein the plasma which permeates through the membrane enters the outer chamber and exits the filter device via the first outlet; whereby the blood which has been depleted of oxygen and/or carbon dioxide, leukocytes and plasma exists and filter device via the second outlet.Type: ApplicationFiled: March 2, 2015Publication date: June 18, 2015Applicant: NEW HEALTH SCIENCES, INC.Inventors: Tatsuro YOSHIDA, Paul J. VERNUCCI
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Patent number: 9005343Abstract: A blood filter device comprising: a housing comprising an outer wall and a first inlet, a first outlet and a second outlet; a membrane which is capable of separating plasma from the blood, wherein the membrane forms an inner chamber; a leukocyte and oxygen and/or carbon dioxide depletion media disposed wherein the inner chamber, the leukocyte and oxygen and/or carbon dioxide depletion media is capable of depleting leukocytes and oxygen and/or carbon dioxide from the blood; an outer chamber disposed between the outer wall and the membrane, wherein the plasma which permeates through the membrane enters the outer chamber and exits the filter device via the first outlet; whereby the blood which has been depleted of oxygen and/or carbon dioxide, leukocytes and plasma exists and filter device via the second outlet.Type: GrantFiled: August 10, 2012Date of Patent: April 14, 2015Assignee: New Health Sciences, Inc.Inventors: Tatsuro Yoshida, Paul J. Vernucci
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Publication number: 20140030694Abstract: An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.Type: ApplicationFiled: September 26, 2013Publication date: January 30, 2014Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, New Health Sciences, Inc.Inventors: William J. FEDERSPIEL, Brian J. FRANKOWSKI, Tatsuro YOSHIDA, Paul J. VERNUCCI
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BLOOD STORAGE BAG SYSTEM AND DEPLETION DEVICES WITH OXYGEN AND CARBON DIOXIDE DEPLETION CAPABILITIES
Publication number: 20130333561Abstract: A blood storage system. The system has a collection bag for red blood cells; an oxygen/carbon dioxide depletion device; a storage bag for red blood cells; and tubing connecting the collection bag to the depletion device and the depletion device to the storage bag. The depletion device includes a receptacle of a solid material having an inlet and an outlet adapted to receiving and expelling a flushing gas; a plurality of hollow fibers or gas-permeable films extending within the receptacle from an entrance to an exit thereof. The hollow fibers or gas-permeable films are adapted to receiving and conveying red blood cells.Type: ApplicationFiled: August 16, 2013Publication date: December 19, 2013Applicant: New Health Sciences, Inc.Inventors: Tatsuro YOSHIDA, Paul J. Vernucci -
Patent number: 8569052Abstract: An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.Type: GrantFiled: May 25, 2011Date of Patent: October 29, 2013Assignees: New Health Sciences, Inc., University of Pittsburgh-Of the Commonwealth System of Higher EducationInventors: William J. Federspiel, Brian J. Frankowski, Tatsuro Yoshida, Paul J. Vernucci
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Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities
Patent number: 8535421Abstract: A blood storage system. The system has a collection bag for red blood cells; an oxygen/carbon dioxide depletion device; a storage bag for red blood cells; and tubing connecting the collection bag to the depletion device and the depletion device to the storage bag. The depletion device includes a receptacle of a solid material having an inlet and an outlet adapted to receiving and expelling a flushing gas; a plurality of hollow fibers or gas-permeable films extending within the receptacle from an entrance to an exit thereof. The hollow fibers or gas-permeable films are adapted to receiving and conveying red blood cells.Type: GrantFiled: October 8, 2010Date of Patent: September 17, 2013Assignee: New Health Sciences, Inc.Inventors: Tatsuro Yoshida, Paul J. Vernucci -
Publication number: 20130047861Abstract: A blood filter device comprising: a housing comprising an outer wall and a first inlet, a first outlet and a second outlet; a membrane which is capable of separating plasma from the blood, wherein the membrane forms an inner chamber; a leukocyte and oxygen and/or carbon dioxide depletion media disposed wherein the inner chamber, the leukocyte and oxygen and/or carbon dioxide depletion media is capable of depleting leukocytes and oxygen and/or carbon dioxide from the blood; an outer chamber disposed between the outer wall and the membrane, wherein the plasma which permeates through the membrane enters the outer chamber and exits the filter device via the first outlet; whereby the blood which has been depleted of oxygen and/or carbon dioxide, leukocytes and plasma exists and filter device via the second outlet.Type: ApplicationFiled: August 10, 2012Publication date: February 28, 2013Applicant: NEW HEALTH SCIENCES, INC.Inventors: Tatsuro YOSHIDA, Paul J. VERNUCCI
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Publication number: 20120129149Abstract: A system for reducing the concentration of oxygen in a fluid including red blood cells includes a housing, a plurality of hollow tubes extending within the housing and adapted for flow of the fluid therethrough, wherein each tube includes an inlet and an outlet, and a carrier system that reduces the concentration of oxygen at an exterior surface of the tubes to facilitate transport of oxygen from the fluid flowing through the tubes to an exterior of the tubes.Type: ApplicationFiled: July 31, 2010Publication date: May 24, 2012Inventors: William J. Federspiel, Tatsuro Yoshida, Paul J. Vernucci, Brian Joseph Frankowski, Laura Wheeler Lund
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Publication number: 20120100523Abstract: An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed within the cartridge and contiguous to and in between the plurality of hollow fibers. The hollow fibers are adapted to receiving and conveying red blood cells. There is another embodiment of an oxygen depletion device and method for removing oxygen from red blood cells.Type: ApplicationFiled: May 25, 2011Publication date: April 26, 2012Inventors: William J. Federspiel, Brian J. Frankowski, Tatsuro Yoshida, Paul J. Vernucci
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BLOOD STORAGE BAG SYSTEM AND DEPLETION DEVICES WITH OXYGEN AND CARBON DIOXIDE DEPLETION CAPABILITIES
Publication number: 20120024156Abstract: A blood storage system. The system has a collection bag for red blood cells; an oxygen/carbon dioxide depletion device; a storage bag for red blood cells; and tubing connecting the collection bag to the depletion device and the depletion device to the storage bag. The depletion device includes a receptacle of a solid material having an inlet and an outlet adapted to receiving and expelling a flushing gas; a plurality of hollow fibers or gas-permeable films extending within the receptacle from an entrance to an exit thereof. The hollow fibers or gas-permeable films are adapted to receiving and conveying red blood cells.Type: ApplicationFiled: October 8, 2010Publication date: February 2, 2012Inventors: Tatsura Yoshida, Paul J. Vernucci -
Patent number: 6629919Abstract: The invention is directed to a centrifugation bowl with a rotating core. The centrifugation bowl includes a rotating bowl body which defines a primary separation chamber. The core, which is generally cylindrically shaped and is disposed within the bowl body, defines a secondary separation chamber. A stationary header assembly may be mounted on top of the bowl body through a rotating seal. The stationary header assembly includes an inlet port for receiving whole blood and an outlet port from which one or more blood components are withdrawn. The inlet port is in fluid communication with a feed tube that extends into the primary separation chamber. The outlet port is in fluid communication with an effluent tube that extends into the bowl body. The effluent tube includes an entryway at a first radial position relative to a central, rotating axis of the bowl.Type: GrantFiled: January 18, 2001Date of Patent: October 7, 2003Assignee: Haemonetics CorporationInventors: YƔir Egozy, Paul J. Vernucci, Lelie E. Rose, Etienne Pages