Abstract: The disclosure features pharmaceutical compositions, methods, and kits featuring dosing regimens and CD101, or a pharmaceutical acceptable salt or neutral form thereof (e.g., CD101 acetate).

Abstract: Provided herein are methods for preventing or reducing the likelihood of a fungal infection or related conditions thereto in a human subject in need thereof. The methods include the administration of one or multiple doses of a pharmaceutical composition including CD101 and any pharmaceutically acceptable excipients, wherein the treatment reduces or eliminates the likelihood of developing a fungal infection.

Abstract: A training simulator provides an immersive virtual training environment depicting an operator performing healthcare tasks to a patient. The simulator includes a head-mounted display unit (HMDU). The HMDU includes a camera, a speaker, a display, and a sensor providing visual and audio output to the operator. The simulator also includes one or more controllers, each having a sensor. The controller sensors and the HMDU sensor output signals representing spatial positioning, angular orientation and movement data of the controllers relative to the patient. The simulator includes a data processing system that models and renders the patient including a condition of the patient, the operator, used healthcare equipment and supplies, changes to the condition of the patient and the used healthcare equipment and supplies, and sensory guidance as to the operator's performance of the healthcare tasks to simulate the virtual training environment and to evaluate the operator's performance.

Abstract: The present invention is a simulator for skill-oriented training. The simulator includes a work piece platform having a sensor, a head-mounted display unit (HMDU) including a camera, a speaker and a sensor providing visual and audio output to an operator, and a controller having a controller sensor. The simulator includes a processor that executes algorithms to simulate a virtual training environment depicting a work piece rendered on the work piece platform. The controller sensor, the HMDU sensor and the platform sensor output signals to the processor representing spatial positioning, angular orientation and movement data of the controller relative to the work piece to render a virtual powder coating spray pattern including a stream having particles charged and emitted from the controller and a powder coating coverage as applied to the work piece during one or more passes of a powder coating spray process performed by the operator.

Abstract: The present invention is a simulator for skill-oriented training. The simulator includes a work piece platform having a sensor, a head-mounted display unit (HMDU) including a camera, a speaker and a sensor providing visual and audio output to an operator, and a controller having a controller sensor. The simulator includes a processor that executes algorithms to simulate a virtual training environment depicting a work piece rendered on the work piece platform. The controller sensor, the HMDU sensor and the platform sensor output signals to the processor representing spatial positioning, angular orientation and movement data of the controller relative to the work piece to render a virtual powder coating spray pattern including a stream having particles charged and emitted from the controller and a powder coating coverage as applied to the work piece during one or more passes of a powder coating spray process performed by the operator.

Abstract: The present invention is a simulator for skill-oriented training. The simulator includes a work piece platform having a sensor, a head-mounted display unit (HMDU) including a camera, a speaker and a sensor providing visual and audio output to an operator, and a controller having a controller sensor. The simulator includes a processor that executes algorithms to simulate a virtual training environment depicting a work piece rendered on the work piece platform. The controller sensor, the HMDU sensor and the platform sensor output signals to the processor representing spatial positioning, angular orientation and movement data of the controller relative to the work piece to render a virtual powder coating spray pattern including a stream having particles charged and emitted from the controller and a powder coating coverage as applied to the work piece during one or more passes of a powder coating spray process performed by the operator.

Abstract: A skill-based training system includes a processing system having a processor, memory coupled to the processor with executable instructions stored therein, and an input-output controller coupled to the processor and to input and output devices. The memory includes lesson plans that outline skill-based tasks and activities, and predetermined performance criteria. The processor is configured by the instructions to present interfaces on the output devices simulating a virtual training environment. The processor is configured to receive input signals representative of performing the tasks and activities in the virtual environment, and to evaluate the performance by comparing the performed tasks and activities to the criteria, to determine a score and to present the score on the output devices.

Abstract: The present invention is a simulator for skill-oriented training. The simulator includes a work piece platform having a sensor, a head-mounted display unit (HMDU) including a camera, a speaker and a sensor providing visual and audio output to an operator, and a controller having a controller sensor. The simulator includes a processor that executes algorithms to simulate a virtual training environment depicting a work piece rendered on the work piece platform. The controller sensor, the HMDU sensor and the platform sensor output signals to the processor representing spatial positioning, angular orientation and movement data of the controller relative to the work piece to render a virtual powder coating spray pattern including a stream having particles charged and emitted from the controller and a powder coating coverage as applied to the work piece during one or more passes of a powder coating spray process performed by the operator.

Abstract: A skill-based training system includes a processing system having a processor, memory coupled to the processor with executable instructions stored therein, and an input-output controller coupled to the processor and to input and output devices. The memory includes lesson plans that outline skill-based tasks and activities, and predetermined performance criteria. The processor is configured by the instructions to present interfaces on the output devices simulating a virtual training environment. The processor is configured to receive input signals representative of performing the tasks and activities in the virtual environment, and to evaluate the performance by comparing the performed tasks and activities to the criteria, to determine a score and to present the score on the output devices.

Abstract: A skill-based training system includes a processing system having a processor, memory coupled to the processor with executable instructions stored therein, and an input-output controller coupled to the processor and to input and output devices. The memory includes lesson plans that outline skill-based tasks and activities, and predetermined performance criteria. The processor is configured by the instructions to present interfaces on the output devices simulating a virtual training environment. The processor is configured to receive input signals representative of performing the tasks and activities in the virtual environment, and to evaluate the performance by comparing the performed tasks and activities to the criteria, to determine a score and to present the score on the output devices.

Abstract: A skill-based training system includes a processing system having a processor, memory coupled to the processor with executable instructions stored therein, and an input-output controller coupled to the processor and to input and output devices. The memory includes lesson plans that outline skill-based tasks and activities, and predetermined performance criteria. The processor is configured by the instructions to present interfaces on the output devices simulating a virtual training environment. The processor is configured to receive input signals representative of performing the tasks and activities in the virtual environment, and to evaluate the performance by comparing the performed tasks and activities to the criteria, to determine a score and to present the score on the output devices.