Abstract: A multi-vendor risk relationship data store may contain electronic records representing a plurality of risk relationships between multiple vendors and an enterprise and, for each risk relationship, an electronic record identifier and a set of attribute values. An information sharing portal computer server may exchange an information request with a remote vendor platform. The information request may be, for example, associated with an employee of a sponsor associated with the vendor platform. The server may process the information request via a customized vendor-specific information sharing portal interface display and execute an algorithm to adjust, based on at least one attribute value, interactions with the vendor platform via the portal interface display. The server may also aggregate information associated with a plurality of vendor platforms and transmit the aggregated information to a remote administrator device associated with the enterprise.

Abstract: The present invention relates to a class of N-cyanopyrrolidines with activity as inhibitors of the deubiquitylating enzyme USP30, having utility in a variety of therapeutic areas, including conditions involving mitochondrial dysfunction, cancer and fibrosis: Formula (I), Formula (II).

Abstract: A method and a system for receiving a user's selection of a content, retrieving data about the content, tracking content consumption, launching a reactive module based on input from the user, registering a timestamped response of the user, the response comprising a graphic symbol is provided. The method may be further comprise receiving content-retrieving information from a second user, searching contents to identify a candidate for the second user's consumption, receiving a selection of a content from the candidate, tracking a position of the content that is selected and being consumed by the second user, launching the reactive module on a second client device based on input from the second user. The virtual platform provides an electronic venue of dynamic communications for content consumers, where users experience pseudo-realtime interactions by seeing the virtual platform's reconstruction of other users' responses that shows reacting users' emotional status.

Abstract: A mode control system and method for controlling an output mode of a broadband radiation source including a photonic crystal fiber (PCF). The mode control system includes at least one detection unit configured to measure one or more parameters of radiation emitted from the broadband radiation source to generate measurement data, and a processing unit configured to evaluate mode purity of the radiation emitted from the broadband radiation source, from the measurement data. Based on the evaluation, the mode control system is configured to generate a control signal for optimization of one or more pump coupling conditions of the broadband radiation source. The one or more pump coupling conditions relate to the coupling of a pump laser beam with respect to a fiber core of the photonic crystal fiber.

Abstract: A method of simulating, on a computer, the activities of a virtual sports league, includes the steps of creating: (a) virtual sports participants, each of which includes a participant statistic that serves to define the performance level of a sports participant, (b) virtual sports teams, each of which has roles for the method's users of virtual team manager, owner, and sports agents, (c) a virtual sports league that includes a season schedule of games between these teams, and (d) formulating the outcome of each of these virtual games to determine the seasonal standings of the teams within the league.

Abstract: A quality control system in a battery manufacturing process includes two or more capacitive measurement apparatuses to obtain a capacitance measurement from two or more intermediate products generated during the battery manufacturing process. The system also includes processing circuitry to obtain the capacitive measurement from the two or more capacitive measurement apparatuses, to determine a characteristic of the corresponding intermediate product, and to control at least one process of the battery manufacturing process that produced at least one of the two or more intermediate products based on the characteristic.

Abstract: Embodiments are directed to structural fuses, structures including the same, and methods of using and forming the same. In an embodiment, a structural fuse is disclosed. The structural fuse includes a first attachment region defining one or more first bolt holes, a second attachment region defining one or more second bolt holes, and a yielding region between the first attachment region and the second attachment region. The yielding region defines one or more slots exhibiting an elongated shape.

Abstract: The application pertains to pharmaceutical combinations of orally administered paclitaxel and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity-type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered paclitaxel (e.g., Taxol® or paclitaxel formulated with Cremophor®) therapy in a subject suffering from cancer.

Abstract: A buffer circuit is disclosed. The buffer circuit includes a command address (C/A) interface to receive an incoming activate (ACT) command and an incoming column address strobe (CAS) command. A first match circuit includes first storage to store failure row address information associated with the memory, and first compare logic. The first compare logic is responsive to the ACT command, to compare incoming row address information to the stored failure row address information. A second match circuit includes second storage to store failure column address information associated with the memory, and second compare logic. The second compare logic is responsive to the CAS command, to compare the incoming column address information to the stored failure column address information. Gating logic maintains a state of a matching row address identified by the first compare logic during the comparison carried out by the second compare logic.

Abstract: The present invention relates to diazine and triazine compounds having activity as Interferon and Interleukin inhibitors, particularly Interferon-gamma, Tumour necrosis factor (TNF)-? and Interleukin-1?, 2, 4, 6, 8, 13 and 17 inhibitors, and to the compounds for use in the treatment of cytokine storm syndrome or cytokine release syndrome.

Abstract: The present invention relates to diazine and triazine compounds having activity as Interleukin inhibitors, particularly Interleukin-1 beta, 2, 4, 6, 8, 13 and 17, and to the compounds for use in the treatment of associated disorders, particularly Alzheimer's Disease, Parkinson's Disease, Asthma, and solid organ transplant rejection.

Abstract: A welding-type power supply including a balanced plate rectifier to rectify high frequency alternating current from one or more transformers. The balanced plate rectifier includes an output terminal symmetrically connected to the plates of the plate rectifiers. The impedance between the output terminal and each plate is substantially equal.

Abstract: Apparatus and methods are disclosed. The apparatus comprises: an abatement chamber of an abatement apparatus which treats an effluent stream from a semiconductor processing tool to provide a combusted effluent stream having effluent particles; and a first atomiser located downstream of the abatement chamber, the first atomiser being configured to produce droplets having a droplet size based on a particle size of the effluent particles to be removed from the combusted effluent stream. In this way, the atomizer may produce droplets which combine with or adhere to the effluent particles which assists in the removal of the effluent particles from the combusted effluent stream.

Abstract: System and method for conducting enhanced oil recovery by establishing a plurality of stacked, alternating slugs of gas and liquid travelling downhole into a subterranean well. The system can include a buffer tank including a liquid inlet through which liquid is received from a liquids source into the buffer tank, a gas inlet through which gas is received from a pressured gas source into the buffer tank, a gas outlet in fluid communication with gas reservoired in the buffer tank, and a liquid outlet in fluid communication with liquid reservoired in the buffer tank. The system can further include a pressure control configured to maintain a specified pressure in gas reservoired within the buffer tank and a fluid dispensing system in fluid communication with the gas and liquid outlets of the buffer tank.

Abstract: An example buckling restrained brace (“BRB”) includes a casing exhibiting a hollow cross-sectional shape defining an interior region. The BRB also includes a core and at least a portion of the core is disposed in the interior region of the casing. For example, the casing may exhibit a first length and the core may exhibit a second length that is greater than the first length such that a portion of the core extends from the casing. The core is separated from the casing by an minimum gap distance along at least a portion of the first length of the casing and a corresponding portion of the second length of the core.

Abstract: A compressor includes a diffuser passage configured to receive refrigerant flow from an impeller of the compressor, where the diffuser passage is at least partially defined by a compressor discharge plate of the compressor. The compressor also includes a variable geometry diffuser positioned within the diffuser passage and configured to adjust a dimension of a refrigerant flow path through the diffuser passage, an actuator coupled to the variable geometry diffuser and configured to adjust a position of the variable geometry diffuser within the diffuser passage, and a controller configured to regulate operation of the actuator.

Abstract: A multi-vendor risk relationship data store may contain electronic records representing a plurality of risk relationships between multiple vendors and an enterprise and, for each risk relationship, an electronic record identifier and a set of attribute values. An information sharing portal computer server may exchange an information request with a remote vendor platform. The information request may be, for example, associated with an employee of a sponsor associated with the vendor platform. The server may process the information request via a customized vendor-specific information sharing portal interface display and execute an algorithm to adjust, based on at least one attribute value, interactions with the vendor platform via the portal interface display. The server may also aggregate information associated with a plurality of vendor platforms and transmit the aggregated information to a remote administrator device associated with the enterprise.

Abstract: Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.

Abstract: The present invention relates to a class of N-cyanopyrrolidines with activity as inhibitors of the deubiquitylating enzyme USP30, having utility in a variety of therapeutic areas, including conditions involving mitochondrial dysfunction, cancer and fibrosis.

Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain 2-amino-N-(amino-oxo-aryl-?6-sulfanylidene)acetamide compounds (referred to herein as ANASIA compounds) that, inter alia, inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase (aaRS) (e.g., bacterial leucyl-tRNA synthetase, LeuRS). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit (e.g., selectively inhibit) bacterial aminoacyl-tRNA synthetase; to treat disorders that are ameliorated by the inhibition (e.g., selective inhibition) of bacterial aminoacyl-tRNA synthetase; to treat bacterial infections; etc.