Patents by Inventor Peggy A. Thompson

Peggy A. Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for an improved antitumor immune response
    Patent number: 11576933
    Abstract: The present disclosure provides compositions and methods for improving an antitumor response against non-inflamed solid tumors. Methods of this disclosure include use of an eIF4A inhibitor to promote infiltration of antitumor lymphocytes into a non inflamed solid tumor. Methods of treating cancer associated with a non-inflamed solid tumor are also provided.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: February 14, 2023
    Assignee: eFFECTOR Therapeutics Inc.
    Inventors: Peggy A. Thompson, Kevin R. Webster
  • EIF4A INHIBITOR COMBINATIONS
    Publication number: 20210299111
    Abstract: The present disclosure relates to methods for ameliorating or treating an eIF4A dependent condition or disease in a subject in need thereof. The methods of the disclosure comprise administering to the subject a therapeutically effective amount of at least one eukaryotic translation initiation factor 4A (eIF4A) inhibitor and a therapeutically effective amount of at least one cyclin-dependent kinase (CDK) inhibitor.
    Type: Application
    Filed: March 23, 2021
    Publication date: September 30, 2021
    Inventors: Peggy A. Thompson, Kevin R. Webster
  • MNK BIOMARKERS AND USES THEREOF
    Publication number: 20210010086
    Abstract: The present disclosure relates to compositions and methods for identifying or diagnosing a human subject having or suspected of having a hyperproliferative disease and who would benefit from treatment with a MNK inhibitor.
    Type: Application
    Filed: May 22, 2020
    Publication date: January 14, 2021
    Inventors: Peggy A. Thompson, Wenqiong Joan Chen, James Appleman
  • COMPOSITIONS AND METHODS FOR AN IMPROVED ANTITUMOR IMMUNE RESPONSE
    Publication number: 20200147135
    Abstract: The present disclosure provides compositions and methods for improving an antitumor response against non-inflamed solid tumors. Methods of this disclosure include use of an eIF4A inhibitor to promote infiltration of antitumor lymphocytes into a non inflamed solid tumor. Methods of treating cancer associated with a non-inflamed solid tumor are also provided.
    Type: Application
    Filed: May 24, 2018
    Publication date: May 14, 2020
    Inventors: Peggy A. THOMPSON, Kevin R. WEBSTER
  • Compositions and methods for treating fibrotic disease
    Patent number: 10576098
    Abstract: The present disclosure relates to compositions and methods for treating or preventing a fibrotic disorder or disease.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: March 3, 2020
    Assignee: eFFECTOR Therapeutics Inc.
    Inventors: James Appleman, Peggy A. Thompson
  • COMPOSITIONS AND METHODS FOR TREATING FIBROTIC DISEASE
    Publication number: 20190038657
    Abstract: The present disclosure relates to compositions and methods for treating or preventing a fibrotic disorder or disease.
    Type: Application
    Filed: May 7, 2018
    Publication date: February 7, 2019
    Inventors: James APPLEMAN, Peggy A. THOMPSON
  • Compositions and methods for treating fibrotic disease
    Patent number: 9993494
    Abstract: The present disclosure relates to compositions and methods for treating or preventing a fibrotic disorder or disease.
    Type: Grant
    Filed: February 7, 2015
    Date of Patent: June 12, 2018
    Assignee: eFFECTOR Therapeutics, Inc.
    Inventors: James Appleman, Peggy A. Thompson
  • COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS
    Publication number: 20170247692
    Abstract: The present disclosure relates to compositions and methods for treating or preventing a neurological disorder.
    Type: Application
    Filed: February 6, 2015
    Publication date: August 31, 2017
    Inventors: James Appleman, Peggy A. Thompson, Vera Huang
  • MNK BIOMARKERS AND USES THEREOF
    Publication number: 20170191136
    Abstract: The present disclosure relates to compositions and methods for identifying or diagnosing a human subject having or suspected of having a hyperproliferative disease and who would benefit from treatment with a MNK inhibitor.
    Type: Application
    Filed: December 23, 2016
    Publication date: July 6, 2017
    Inventors: Peggy A. Thompson, Wenqiong Joan Chen, James Appleman
  • COMPOSITIONS AND METHODS FOR TREATING FIBROTIC DISEASE
    Publication number: 20150224132
    Abstract: The present disclosure relates to compositions and methods for treating or preventing a fibrotic disorder or disease.
    Type: Application
    Filed: February 7, 2015
    Publication date: August 13, 2015
    Inventors: James Appleman, Peggy A. Thompson
  • METHOD OF INHIBITING HEPATITUS C VIRUS BY COMBINATION OF A 5,6-DIHYDRO-1H-PYRIDIN-2-ONE AND ONE OR MORE ADDITIONAL ANTIVIRAL COMPOUNDS
    Publication number: 20140066396
    Abstract: The invention is directed to a method of treating infections by hepatitis C virus by administering N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1?6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide and one or more additional antiviral compounds or pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: November 8, 2013
    Publication date: March 6, 2014
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Peter S. Dragovich, Peggy A. Thompson, Frank Ruebsam
  • 5,6-dihydro-1H-pyridin-2-one compounds
    Patent number: 8129368
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds of formula: wherein R is C1-C6 alkyl or (Aryl)CH2-,and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: March 6, 2012
    Assignee: Anadys Pharmaceuticals, Inc.
    Inventors: Frank Ruebsam, Chinh V Tran, Douglas E. Murphy, Peggy A. Thompson, Peter Dragovich, Stephen E. Webber
  • METHOD OF INHIBITING HEPATITUS C VIRUS BY COMBINATION OF A 5,6-DIHYDRO-1H-PYRIDIN-2-ONE AND ONE OR MORE ADDITIONAL ANTIVIRAL COMPOUNDS
    Publication number: 20110229438
    Abstract: The invention is directed to a method of treating infections by hepatitis C virus by administering N-{3-[(1R,2S,7R,8S)-3-(4-fluoro-benzyl)-6-hydroxy-4-oxo-3-aza-tricyclo[6.2.1.02,7]undec-5-en-5-yl]-1,1-dioxo-1,4-dihydro-1?6-benzo[1,2,4]thiadiazin-7-yl}-methanesulfonamide and one or more additional antiviral compounds or pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: October 9, 2009
    Publication date: September 22, 2011
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Peter Dragovich, Peggy A. Thompson, Frank Ruebsam
  • 5,6-DIHYDRO-1H-PYRIDIN-2-ONE COMPOUNDS
    Publication number: 20100119481
    Abstract: The invention is directed to 5,6-dihydro-1H-pyridin-2-one compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.
    Type: Application
    Filed: October 9, 2009
    Publication date: May 13, 2010
    Applicant: Anadys Pharmaceuticals, Inc.
    Inventors: Frank Ruebsam, Chinh V. Tran, Douglas E. Murphy, Peggy A. Thompson, Peter Dragovich, Stephen E. Webber