Patents by Inventor Penelope J. Toothman

Penelope J. Toothman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity TGF.beta. nucleic acid ligands
    Patent number: 5731144
    Abstract: Methods are described for the identification and preparation of high-affinity nucleic acid ligands to TGF.beta.. Included in the invention are specific RNA and ssDNA ligands to TGF.beta.1 identified by the SELEX method. Also included are RNA ligands that inhibit the interaction of TGF.beta.1 with its receptor.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: March 24, 1998
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Penelope J. Toothman, Steven Ringquist, Larry Gold
  • High affinity TGF.beta. nucleic acid ligands and inhibitors
    Patent number: 5731424
    Abstract: Methods are described for the identification and preparation of high-affinity nucleic acid ligands to TGF.beta.. Included in the invention are specific RNA and ssDNA ligands to TGF.beta.1 identified by the SELEX method. Also included are RNA ligands that inhibit the interaction of TGF.beta.1 with its receptor.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: March 24, 1998
    Assignee: NeXstar Pharmaceuticals, Inc.
    Inventors: Penelope J. Toothman, Steven Ringquist, Larry Gold