Abstract: A communication device comprising: a first radio capable of communicating according to a first protocol and having a set of operational modes; and a second radio capable of communicating according to a second protocol, the communication device being configured to, in dependence on one or more communications by the second radio in accordance with the second protocol, selecting one mode of operation for the first radio from the set of operational modes, wherein said one or more communications comprises: sending a first message; and a response or non-response to the first message.

Abstract: A method of and apparatus for, detecting an intrusion into a volume defined relative to a path across an opening along which path a closure member for the opening can be controllably displaced to define a gap in the opening, the gap being bounded on one side by the closure member and on the other side to the one side by a boundary member; the volume including at least one threshold region on at least one side of the path; the volume having as a base the threshold region and rising above the threshold region; a first group of at least two emitters of electromagnetic signals located on either the closure member or the boundary and directed into the volume and a second group of at least two receivers for electromagnetic signals located on the opposite side of the gap to the emitters; emissions from the emitters being directed into the volume but not directly towards the receivers; the emitters and receivers forming part of a network including processing means which form a compound sensor for use in monitoring op

Abstract: The application discloses a microplate, wherein the openings of the wells for receiving reagents have a collar, wherein the collar comprises at least two upwardly extending rims, wherein the rims are radially separated by a gap (4), and wherein the rims are circumferentially closed. Furthermore, multiwall strips with such double rimmed wells are disclosed.

Abstract: The invention relates to specific binding members, particularly antibodies and active fragments thereof, which recognize an aberrant post-translationally modified, particularly an aberrant glycosylated form of the EGFR. The binding members, particularly antibodies and fragments thereof, of the invention do not bind to EGFR on normal cells in the absence of amplification of the wild-type gene and are capable of binding the de2-7 EGFR at an epitope which is distinct from the junctional peptide. Antibodies of this type are exemplified by the novel antibody 806 whose VH and VL sequences are illustrated as SEQ ID NOs: 2 and 4 and chimeric antibodies thereof as exemplified by ch806.

Abstract: The present invention relates to a multiwell strip comprising a frame portion consisting of a first stiff material, and a plurality of wells arranged in a line and consisting of a second material, which is not as stiff as the first material. Furthermore, the present invention relates to a multiwell-frame for obtaining a multiwell strip according to the present invention and methods for producing a multiwell strip according to the present invention.

Abstract: A process for preparing isohumulone compositions, which process provides an improvement over the extant art, and yields an isohumulone preparation derived from a hop extract of high yield and purity, which has excellent physical stability, and is essentially free from undesirable lupulones, fatty acids, hop oils and degradation compounds.

Abstract: The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to amplified epidermal growth factor receptor (EGFR) and to the de2-7 EGFR truncation of the EGFR. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof.

Abstract: A drier information system is provided including display means relating to a given region of the system which means serves, at least while a drying cycle is in operation, to provide a visual display indicating at least one of the following parameters: the extent of the region; a boundary of the region; direction or example of manipulation of a pair of hands or other article while in the region to provide for a preferred drying sequence. The visual display can represent the parameters as a two dimensional array within or adjacent the region. Alternatively the visual display can represent the parameters as a virtual or actual three dimensional array within or adjacent the region.

Abstract: The present invention relates to a heat sealable member comprising a sheet of heat sealable material to a multiwell plate, wherein the sheet is mounted in a frame, and wherein said frame is sized to fit over a multiwell plate so that the sheet is contacted with at least one of the rims of the top of the plate and the individual wells; as well as to the use of the heat sealable member with automatic plate handling apparatus, especially in PCR processes. The present invention further relates to a method for sealing multiwell plates.

Abstract: An air displacing device for transferring air from a first location to a second location comprising a housing including a fan, a prime mover for the fan, means defining an air inlet to receive air from the first location, and an air outlet to deliver air to the second location and a duct for air through the housing from the inlet to the outlet, the fan being operable by way of the prime mover to cause air to be displaced along the duct from the inlet to the outlet, the housing serving to define a datum plane characterized in that the housing has external members adapted for displacement between a first, standby, configuration where the projection of the housing from the datum plane is a minimum and so the volume of the housing is a minimum and a second, working, configuration where the projection of the housing from the datum plane is a maximum and so the volume of the housing is a maximum.

Abstract: The present invention relates to compositions with effective metal chelating activity and utility as natural antioxidants in food, beverages, nutritional supplements and cosmetics. The compositions of the present invention may be prepared by enzymatically hydrolyzing hypoallergenic protein isolates derived from vegetables, for example yellow pea (Pisum sativum), and/or grains using specific enzymes.

Abstract: The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to EGFR on tumor cells that overexpress EGFR, and on tumor cells that express the truncated version of the EGFR receptor, de2-7 EGF. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof.

Abstract: The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to EGFR on tumor cells that overexpress EGFR, and on tumor cells that express the truncated version of the EGFR receptor, de2-7 EGF. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof.

Abstract: The pharmaceutical use of amylases related to Bacillus alpha-amylases of SEQ ID NOs: 1-3, optionally in combination with a lipase and/or a protease. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II. The amylases of SEQ ID NOs: 1-3 are variants of amylases from Bacillus stearothermophilus, Bacillus licheniformis and Bacillus sp. The amylases of the invention have an improved efficacy in vivo, an improved pH-profile, a high specific activity, and/or an improved starch degradation profile.

Abstract: The present invention discloses a solution that automatically decomposes a batch process into multiple units of work without changing code of a pre-existing batch application. In the solution, the batch application is first analyzed to identify a set of processing segments or units of work, where each unit of work is of a size that minimizes interference with other data accesses. Once each unit of work is defined, these units can execute one at a time. A syncpoint can be established for each unit before it is executed, which locks the records included in the unit. After the unit of work executes, the record lock can be released and a new syncpoint can be established for the next unit. If an execution problem occurs, execution for the unit of work can be terminated and chances can be restored to the syncpoint.

Abstract: A process for preparing tetrahydroisohumulone compositions from a hop extract, which process provides an improvement over the extant art, and provides a tetrahydroisohumulone preparation of high yield and purity, which tetrahydroisohumulone preparation exhibits excellent physical stability, and is essentially free from undesirable lupulones, fatty acids, hop oils and degradation compounds.

Abstract: The present invention relates to specific binding members, particularly antibodies and fragments thereof, which bind to amplified epidermal growth factor receptor (EGFR) and to the de2-7 EGFR truncation of the EGFR. In particular, the epitope recognized by the specific binding members, particularly antibodies and fragments thereof, is enhanced or evident upon aberrant post-translational modification. These specific binding members are useful in the diagnosis and treatment of cancer. The binding members of the present invention may also be used in therapy in combination with chemotherapeutics or anti-cancer agents and/or with other antibodies or fragments thereof.

Abstract: A method of operating a data processing system comprises executing a batch application, the executing comprising reading one or more inputs from one or more data files, performing updates on one or more records according to the or each input read from a data file, and issuing a syncpoint when said updates are completed. During the execution of the batch application, syncpoints are periodically issued and checkpoints are less frequently issued. Following detection of a failure of the batch application, the batch application is restarted with the last issued checkpoint, and the batch application is executed by reading one or more inputs from one or more data files, but not performing updates on said records, until the last issued syncpoint is reached.

Abstract: The present invention provides metal-chelating or sequestering antioxidant compositions, derived from edible herbs, spices, fruits, vegetables and/or grains, useful for incorporating into foods, beverages, nutritional supplements and cosmetics for the purpose of enhancing the stability of said food, beverage or cosmetic. This invention provides processes for preparing these antioxidant, stability-enhancing compositions.

Abstract: The invention relates to specific binding members, particularly antibodies and active fragments thereof, which recognize an aberrant post-translationally modified, particularly an aberrant glycosylated form of the EGFR. The binding members, particularly antibodies and fragments thereof, of the invention do not bind to EGFR on normal cells in the absence of amplification of the wild-type gene and are capable of binding the de2-7 EGFR at an epitope which is distinct from the junctional peptide. Antibodies of this type are exemplified by the novel antibody 806 whose VH and VL sequences are illustrated as SEQ ID NOs: 2 and 4 and chimeric antibodies thereof as exemplified by ch806.