Patents by Inventor Peter John Friend
Peter John Friend has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11540508Abstract: An organ perfusion system comprises: a perfusion fluid circuit (16) arranged to circulate perfusion fluid through the organ; a surrogate organ (126) arranged to be connected into the circuit in place of the organ so that the circuit can circulate fluid through the surrogate organ; and organ sensing means arranged to distinguish between the presence of the organ in the circuit and the presence of the surrogate organ in the circuit. The sensing means may comprise one or more pressure sensors (136, 137, 138), or a flow meter (125). Further aspects relate to adjusting the content of at least one component, such as oxygen or a nutrient, in the perfusion fluid. Bubble detection means (113), and means (74) to measure the amount of fluid secreted by or leaked from the organ, may also be provided.Type: GrantFiled: November 8, 2016Date of Patent: January 3, 2023Assignee: Organox LimitedInventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
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Publication number: 20200128813Abstract: A disposable set of components for an organ perfusion system comprising a fluid supply duct for supplying fluid to the organ, a fluid removal duct for removing fluid from the organ, and a surrogate organ removably connected between the fluid supply duct and the fluid removal duct so as to form a fluid circuit, so that fluid can be circulated in the circuit in preparation for connection of the organ.Type: ApplicationFiled: December 23, 2019Publication date: April 30, 2020Inventors: Stuart Brian William Kay, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
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Patent number: 10362780Abstract: A perfusion system for the perfusion of an organ comprises a perfusion fluid circuit (16) for circulating perfusion fluid through the organ, oxygenation means (14) for adding oxygen into the perfusion fluid, and an oxygen supply arranged to supply oxygen to the oxygenation means. The oxygen supply comprises an oxygen concentrator.Type: GrantFiled: November 8, 2012Date of Patent: July 30, 2019Assignee: Organox LimitedInventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, Leslie James Russell, Peter John Friend, Constantin C. Coussios
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Publication number: 20170049096Abstract: An organ perfusion system comprises: a perfusion fluid circuit (16) arranged to circulate perfusion fluid through the organ; a surrogate organ (126) arranged to be connected into the circuit in place of the organ so that the circuit can circulate fluid through the surrogate organ; and organ sensing means arranged to distinguish between the presence of the organ in the circuit and the presence of the surrogate organ in the circuit. The sensing means may comprise one or more pressure sensors (136, 137, 138), or a flow meter (125). Further aspects relate to adjusting the content of at least one component, such as oxygen or a nutrient, in the perfusion fluid. Bubble detection means (113), and means (74) to measure the amount of fluid secreted by or leaked from the organ, may also be provided.Type: ApplicationFiled: November 8, 2016Publication date: February 23, 2017Inventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
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Publication number: 20170042141Abstract: A disposable set of components for an organ perfusion system comprising a fluid supply duct for supplying fluid to the organ, a fluid removal duct for removing fluid from the organ, and a surrogate organ removably connected between the fluid supply duct and the fluid removal duct so as to form a fluid circuit, so that fluid can be circulated in the circuit in preparation for connection of the organ.Type: ApplicationFiled: October 31, 2016Publication date: February 16, 2017Inventors: Stuart Brian William Kay, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
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Publication number: 20150004677Abstract: A perfusion system for the perfusion of an organ comprises a perfusion fluid circuit (16) for circulating perfusion fluid through the organ, oxygenation means (14) for adding oxygen into the perfusion fluid, and an oxygen supply arranged to supply oxygen to the oxygenation means. The oxygen supply comprises an oxygen concentrator.Type: ApplicationFiled: November 8, 2012Publication date: January 1, 2015Inventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, Leslie James Russell, Peter John Friend, Constantin C. Coussios
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Publication number: 20140377849Abstract: A disposable set of components for an organ perfusion system comprising a fluid supply duct for supplying fluid to the organ, a fluid removal duct for removing fluid from the organ, and a surrogate organ removably connected between the fluid supply duct and the fluid removal duct so as to form a fluid circuit, so that fluid can be circulated in the circuit in preparation for connection of the organ.Type: ApplicationFiled: November 8, 2012Publication date: December 25, 2014Inventors: Stuart Brian William Kay, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
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Publication number: 20140308654Abstract: An organ perfusion system comprises: a perfusion fluid circuit (16) arranged to circulate perfusion fluid through the organ; a surrogate organ (126) arranged to be connected into the circuit in place of the organ so that the circuit can circulate fluid through the surrogate organ; and organ sensing means arranged to distinguish between the presence of the organ in the circuit and the presence of the surrogate organ in the circuit. The sensing means may comprise one or more pressure sensors (136, 137, 138), or a flow meter (125). Further aspects relate to adjusting the content of at least one component, such as oxygen or a nutrient, in the perfusion fluid. Bubble detection means (113), and means (74) to measure the amount of fluid secreted by or leaked from the organ, may also be provided.Type: ApplicationFiled: November 8, 2012Publication date: October 16, 2014Applicant: Organox LimitedInventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, JR., David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
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Patent number: 8435520Abstract: A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition.Type: GrantFiled: February 11, 2011Date of Patent: May 7, 2013Inventors: Hendrik J. Schuurman, Emanuele Luigi Maria Cozzi, Francoise Richard, Guy Taccard, David James Graham White, Peter John Friend, John Wallwork, Paolo Brenner
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Publication number: 20110142953Abstract: A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition.Type: ApplicationFiled: February 11, 2011Publication date: June 16, 2011Inventors: Hendrik J. SCHUURMAN, Emanuele Luigi COZZI, Francoise RICHARD, Guy TACCARD, David James Graham WHITE, Peter John FRIEND, John WALLWORK, Paolo BRENNER
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Publication number: 20080199478Abstract: A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition.Type: ApplicationFiled: April 24, 2008Publication date: August 21, 2008Inventors: Hendrik J. SCHUURMAN, Emanuele Luigi Cozzi, Francoise Richard, Guy Taccard, David James Graham White, Peter John Friend, John Wallwork, Paolo Brenner
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Publication number: 20020132764Abstract: A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition.Type: ApplicationFiled: November 7, 2001Publication date: September 19, 2002Inventors: Hendrik J. Schuurman, Emanuele Luigi Cozzi, Francoise Richard, Guy Taccard, David James Graham White, Peter John Friend, John Wallwork, Paolo Brenner