Patents by Inventor Peter John Friend

Peter John Friend has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11540508
    Abstract: An organ perfusion system comprises: a perfusion fluid circuit (16) arranged to circulate perfusion fluid through the organ; a surrogate organ (126) arranged to be connected into the circuit in place of the organ so that the circuit can circulate fluid through the surrogate organ; and organ sensing means arranged to distinguish between the presence of the organ in the circuit and the presence of the surrogate organ in the circuit. The sensing means may comprise one or more pressure sensors (136, 137, 138), or a flow meter (125). Further aspects relate to adjusting the content of at least one component, such as oxygen or a nutrient, in the perfusion fluid. Bubble detection means (113), and means (74) to measure the amount of fluid secreted by or leaked from the organ, may also be provided.
    Type: Grant
    Filed: November 8, 2016
    Date of Patent: January 3, 2023
    Assignee: Organox Limited
    Inventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
  • Publication number: 20200128813
    Abstract: A disposable set of components for an organ perfusion system comprising a fluid supply duct for supplying fluid to the organ, a fluid removal duct for removing fluid from the organ, and a surrogate organ removably connected between the fluid supply duct and the fluid removal duct so as to form a fluid circuit, so that fluid can be circulated in the circuit in preparation for connection of the organ.
    Type: Application
    Filed: December 23, 2019
    Publication date: April 30, 2020
    Inventors: Stuart Brian William Kay, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
  • Patent number: 10362780
    Abstract: A perfusion system for the perfusion of an organ comprises a perfusion fluid circuit (16) for circulating perfusion fluid through the organ, oxygenation means (14) for adding oxygen into the perfusion fluid, and an oxygen supply arranged to supply oxygen to the oxygenation means. The oxygen supply comprises an oxygen concentrator.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: July 30, 2019
    Assignee: Organox Limited
    Inventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, Leslie James Russell, Peter John Friend, Constantin C. Coussios
  • Publication number: 20170049096
    Abstract: An organ perfusion system comprises: a perfusion fluid circuit (16) arranged to circulate perfusion fluid through the organ; a surrogate organ (126) arranged to be connected into the circuit in place of the organ so that the circuit can circulate fluid through the surrogate organ; and organ sensing means arranged to distinguish between the presence of the organ in the circuit and the presence of the surrogate organ in the circuit. The sensing means may comprise one or more pressure sensors (136, 137, 138), or a flow meter (125). Further aspects relate to adjusting the content of at least one component, such as oxygen or a nutrient, in the perfusion fluid. Bubble detection means (113), and means (74) to measure the amount of fluid secreted by or leaked from the organ, may also be provided.
    Type: Application
    Filed: November 8, 2016
    Publication date: February 23, 2017
    Inventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
  • Publication number: 20170042141
    Abstract: A disposable set of components for an organ perfusion system comprising a fluid supply duct for supplying fluid to the organ, a fluid removal duct for removing fluid from the organ, and a surrogate organ removably connected between the fluid supply duct and the fluid removal duct so as to form a fluid circuit, so that fluid can be circulated in the circuit in preparation for connection of the organ.
    Type: Application
    Filed: October 31, 2016
    Publication date: February 16, 2017
    Inventors: Stuart Brian William Kay, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
  • Publication number: 20150004677
    Abstract: A perfusion system for the perfusion of an organ comprises a perfusion fluid circuit (16) for circulating perfusion fluid through the organ, oxygenation means (14) for adding oxygen into the perfusion fluid, and an oxygen supply arranged to supply oxygen to the oxygenation means. The oxygen supply comprises an oxygen concentrator.
    Type: Application
    Filed: November 8, 2012
    Publication date: January 1, 2015
    Inventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, Leslie James Russell, Peter John Friend, Constantin C. Coussios
  • Publication number: 20140377849
    Abstract: A disposable set of components for an organ perfusion system comprising a fluid supply duct for supplying fluid to the organ, a fluid removal duct for removing fluid from the organ, and a surrogate organ removably connected between the fluid supply duct and the fluid removal duct so as to form a fluid circuit, so that fluid can be circulated in the circuit in preparation for connection of the organ.
    Type: Application
    Filed: November 8, 2012
    Publication date: December 25, 2014
    Inventors: Stuart Brian William Kay, David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
  • Publication number: 20140308654
    Abstract: An organ perfusion system comprises: a perfusion fluid circuit (16) arranged to circulate perfusion fluid through the organ; a surrogate organ (126) arranged to be connected into the circuit in place of the organ so that the circuit can circulate fluid through the surrogate organ; and organ sensing means arranged to distinguish between the presence of the organ in the circuit and the presence of the surrogate organ in the circuit. The sensing means may comprise one or more pressure sensors (136, 137, 138), or a flow meter (125). Further aspects relate to adjusting the content of at least one component, such as oxygen or a nutrient, in the perfusion fluid. Bubble detection means (113), and means (74) to measure the amount of fluid secreted by or leaked from the organ, may also be provided.
    Type: Application
    Filed: November 8, 2012
    Publication date: October 16, 2014
    Applicant: Organox Limited
    Inventors: Stuart Brian William Kay, Sebastien Antoine Yves Cuvelier, Jonathan Richard Oakley, JR., David George Robinson, Philip David Canner, Peter Alan Salkus, Leslie James Russell, Peter John Friend, Constantin C. Coussios
  • Patent number: 8435520
    Abstract: A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition.
    Type: Grant
    Filed: February 11, 2011
    Date of Patent: May 7, 2013
    Inventors: Hendrik J. Schuurman, Emanuele Luigi Maria Cozzi, Francoise Richard, Guy Taccard, David James Graham White, Peter John Friend, John Wallwork, Paolo Brenner
  • Publication number: 20110142953
    Abstract: A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition.
    Type: Application
    Filed: February 11, 2011
    Publication date: June 16, 2011
    Inventors: Hendrik J. SCHUURMAN, Emanuele Luigi COZZI, Francoise RICHARD, Guy TACCARD, David James Graham WHITE, Peter John FRIEND, John WALLWORK, Paolo BRENNER
  • Publication number: 20080199478
    Abstract: A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition.
    Type: Application
    Filed: April 24, 2008
    Publication date: August 21, 2008
    Inventors: Hendrik J. SCHUURMAN, Emanuele Luigi Cozzi, Francoise Richard, Guy Taccard, David James Graham White, Peter John Friend, John Wallwork, Paolo Brenner
  • Publication number: 20020132764
    Abstract: A pharmaceutical composition useful in the treatment or prevention of transgenic xenograft rejection comprising immunosuppressant compounds selected from the group consisting of an IL-2 transcription inhibitor and immunosuppressant compounds that immunosuppress for B-cell-mediated or antibody-mediated rejection of xenografts, and pharmaceutically acceptable diluents or carriers, and a method of preventing hyperacute rejection, reducing early graft damage, improving early xenograft function and promoting long term survival of said transgenic xenografts comprising the steps of i) contacting the body fluid removed from a human recipient with a xenoantigenic material which is bound to a biocompatible solid support, ii) reintroducing the treated body fluid into the recipient, and iii) treating the recipient with said pharmaceutical composition.
    Type: Application
    Filed: November 7, 2001
    Publication date: September 19, 2002
    Inventors: Hendrik J. Schuurman, Emanuele Luigi Cozzi, Francoise Richard, Guy Taccard, David James Graham White, Peter John Friend, John Wallwork, Paolo Brenner