Abstract: A technique is disclosed for generating variance data and a variance map from measured projection data acquired from a tomography system. The method comprises accessing the measured projection data from the tomography system. The method further comprises generating the variance map from the measured projection data and displaying, analyzing or processing the variance map. The variance data is determined based upon a statistical model from measured image data, and may be used for image analysis, data acquisition, in computer aided diagnosis routines, and so forth.

Abstract: Methods for energy-sensitive computed tomography systems that use checkerboard filtering. A method of enhancing image analysis of projection data acquired using a detector configured with a checkerboard filter includes disposing in a system a detector to receive a transmitted beam of X-rays traversing through an object, where the system is configured so the detector receives both high- and one of total- and low-energy projection data; receiving the high- and one of total- and low-energy projection data at the detector; and then estimating an effective atomic number of the object and/or processing the projection data so as to mitigate reconstruction artifacts. The present invention has been described in terms of specific embodiment(s), and it is recognized that equivalents, alternatives, and modifications, aside from those expressly stated, are possible and within the scope of the appended claims.

Abstract: A method is provided for processing an image. The method comprises identifying one or more contours or surfaces in a two-dimensional or three-dimensional image generated from a set of projection data. The set of projection data is differentially processed based on the identification of those data points that largely define one or more contours or surfaces. An enhanced image set is reconstructed from the set of processed projection data.

Abstract: A system for producing at least one high flux photon beam is provided. The system includes two or more photon sources configured to produce photon beams, and at least one first stage optic device coupled to at least one of the photon sources and providing at least one focused photon beam through total internal reflection, wherein at least one of the photon beams and the focused photon beams are combined at a virtual focal spot.

Abstract: A system, method, and apparatus includes a computed tomography (CT) system having a rotatable gantry, an x-ray source, a generator, a detector having pixels and positioned to receive x-rays, and a computer. The computer is programmed to acquire CT data representative of an object, determine a first subset of the CT data, determine a second subset of the CT data, and determine a difference between the first and second subsets of the CT data to identify a motion region in the object. The computer is also programmed to update image data reconstructed from a first portion of the first subset of the CT data and corresponding to the region and reconstruct an image based on the updated image data and non-updated image data. The non-updated image data is reconstructed from a second portion the first subset of the CT data.

Abstract: A method and system for motion estimation and compensation are disclosed. Initially, a set of one or more initial images is reconstructed using acquired imaging data. Further, one or more regions of interest are identified in this set of reconstructed initial images. At least a set of filters is applied to the identified regions of interest to generate a sequence of filtered images. Particularly, each of the filtered images in the generated sequence of filtered images includes data acquired near a different reference point. Subsequently, a motion path corresponding to each region of interest is determined based on one or more correspondences in the sequence of filtered images.

Abstract: A method and system for presenting images of an object of interest is provided. The method includes producing one or more cine loops of images from at least one of multiple projection views or multiple reconstructed 3D images including a 3D volume obtained from one or more beamlines. The method also includes generating at least one combined image including a first component and a second component wherein the first component and the second component each include one of a baseline image or the one or more cine loops of images. The combined image is generated via at least one of superimposing the first component and the second component, displaying the first component adjacent to the second component, and toggling between the first component and the second component. The method also includes displaying the at least one combined image.

Abstract: A method for making a secondary collimator that includes at least one plate having a plurality of slits defined therein includes determining a gap thickness between plate positions of the secondary collimator based on at least one dimension of the at least one plate and fabricating a base plate from a base plate blank. The base plate includes at least two slots being spaced apart by the gap thickness. The at least one plate is inserted into a first slot of the at least two slots to form the secondary collimator.

Abstract: An energy-sensitive computed tomography system is provided. The energy-sensitive computed tomography system includes an X-ray source configured to emit an X-ray beam resulting from electrons impinging upon a target material. The energy-sensitive computed tomography system also includes an object positioned within the X-ray beam. The energy-sensitive computed tomography system further includes a detector configured to receive a transmitted beam of the X-rays through the object. The energy-sensitive computed tomography system also includes a filter having an alternating pattern disposed between the X-ray source and the detector, the filter configured to facilitate measuring projection data that can be used to generate low-energy and high-energy spectral information.

Abstract: An integrated, multi-sensor, Level 1 screening device is described, which system provides a next-generation Explosives Detection System (EDS) that enables high throughput, while drastically reducing false alarms. In exemplary embodiments, the present system comprises a non-rotational, Computed Tomography (CT) system and a non-translational, X-ray diffraction (XRD) system, both in an inline configuration.

Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, at least one x-ray source coupled to the gantry and configured to project x-rays toward the object, a detector coupled to the gantry and having a scintillator therein and configured to receive x-rays that pass through the object, and a generator configured to energize the at least one x-ray source.

Abstract: A system includes a generator configured to output at least one voltage level and an x-ray source configured to generate x-rays directed toward an object. The system includes a module coupled to the output of the generator and to an input of the x-ray source and configured to switch or assist in switching an output to the x-ray source between a first voltage level and a second voltage level.

Abstract: An optic device includes a multilayer zone forming a redirection section for redirecting and transmitting photons through total internal reflection, each multilayer zone including a high index material having a first real refractive index n1 and a first absorption coefficient ?1, a low index material having a second real refractive index n2 and a second absorption coefficient ?2, and a grading zone disposed between the high index material and the low index material and including a grading layer having a third real refractive index n3 and a third absorption coefficient ?3, wherein n1>n3>n2.

Abstract: Systems and methods are provided for acquiring and reconstructing projection data that is mathematically complete or sufficient using a computed tomography (CT) system having stationary distributed X-ray sources and detector arrays. In one embodiment, a distributed source is provided as arcuate segments offset in the X-Y plane and along the Z-axis.

Abstract: A contraband detection system includes a first contraband detection apparatus designed to perform a first scan on an object and a second contraband detection apparatus positioned in-line with the first contraband detection apparatus to perform a second scan on the object. A computer is included in the contraband detection system and is programmed to cause the first contraband detection apparatus to perform the first scan and acquire object data therefrom. The computer is further programmed to identify one or more regions of interest (ROI) in the object based on the object data, cause the second contraband detection apparatus to perform the second scan on the one or more identified ROIs, and acquire object data from the second scan.

Abstract: Methods for energy-sensitive computed tomography systems that use checkerboard filtering. A method of enhancing image analysis of projection data acquired using a detector configured with a checkerboard filter includes disposing in a system a detector to receive a transmitted beam of X-rays traversing through an object, where the system is configured so the detector receives both high- and one of total- and low-energy projection data; receiving the high- and one of total- and low-energy projection data at the detector; and then estimating an effective atomic number of the object and/or processing the projection data so as to mitigate reconstruction artifacts. The present invention has been described in terms of specific embodiment(s), and it is recognized that equivalents, alternatives, and modifications, aside from those expressly stated, are possible and within the scope of the appended claims.

Abstract: A technique is provided for the temporal interpolation of a projection data set acquired of a dynamic object, such as a heart. The projection data set is acquired using a slowly rotating gantry and a distributed X-ray source. The projection data may be interpolated at each view position to a selected instant of time, such as relative to a cardiac phase. The resulting interpolated projection data characterize the projection data at each view location at any instant in time. The set of interpolated projection data may then be reconstructed to generate images and/or volume with improved temporal resolution.

Abstract: A system and method for scanning objects using a non-translational x-ray diffraction (XRD) system is disclosed. The system includes a scanning area through which an object to be scanned traverses and a distributed x-ray source having a plurality of focal spot locations. The distributed x-ray source is affixed on the scanning area and is configured to emit x-rays towards the object as a series of parallel x-ray beams. A stationary detector arrangement is affixed on another side of the scanning area generally opposite the distributed x-ray source and is configured to measure a coherent scatter spectra of the x-rays after passing through the object. A data acquisition system (DAS) is connected to the detector arrangement and is configured to measure the coherent scatter spectra, which is utilized to generate XRD data and determine a material composition of at least a portion of the object from the XRD data.

Abstract: A multi-energy imaging system and method for selectively generating high-energy X-rays and low-energy X-ray beams are described. A pair of optic devices are used, one optic device being formed to emit high X-ray energies and the other optic device being formed to emit low X-ray energies. A selective filtering mechanism is used to filter the high X-ray energies from the low X-ray energies. The optic devices have at least a first solid phase layer having a first index of refraction with a first photon transmission property and a second solid phase layer having a second index of refraction with a second photon transmission property. The first and second layers are conformal to each other.

Abstract: Systems and methods are provided for acquiring and reconstructing projection data using a computed tomography (CT) system having stationary distributed X-ray sources and detector arrays. In one embodiment, a non-sequential activation of X-ray source locations on an annular source is employed to acquire projection data. In another embodiment, a distributed source is tilted relative to an axis of the scanner to acquire the projection data. In a further embodiment, a plurality of X-ray source locations on an annular source are activated such that the aggregated signals correspond to two or more sets of spatially interleaved helical scan data.