Patents by Inventor Pierre-Emmanuel Ceccaldi

Pierre-Emmanuel Ceccaldi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In vitro blood-brain barrier model
    Patent number: 10591466
    Abstract: The invention is in the domain of delivery of molecules to brain cells across the blood-brain barrier. The invention relates to a novel polypeptide-based carrier that allows the efficient delivery of an effector peptide, to neuron cells across the blood-brain barrier, and to methods for the production and testing of such carrier, including a model for testing the capacity of such molecule to cross the blood-brain barrier and/or the toxicity of molecules on the blood brain barrier and/or the capacity of molecules that have crossed to target human brain cells (e/g. neurons, astrocytes and microglial cells).
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: March 17, 2020
    Assignees: INSTITUT PASTEUR, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Christophe Prehaud, Monique Lafon, Pierre-Emmanuel Ceccaldi, Philippe Afonso, Pierre Lafaye
  • NEW IN VITRO BLOOD-BRAIN BARRIER MODEL
    Publication number: 20170241988
    Abstract: The invention is in the domain of delivery of molecules to brain cells across the blood-brain barrier. The invention relates to a novel polypeptide-based carrier that allows the efficient delivery of an effector peptide, to neuron cells across the blood-brain barrier, and to methods for the production and testing of such carrier, including a model for testing the capacity of such molecule to cross the blood-brain barrier and/or the toxicity of molecules on the blood brain barrier and/or the capacity of molecules that have crossed to target human brain cells (e/g. neurons, astrocytes and microglial cells).
    Type: Application
    Filed: September 9, 2015
    Publication date: August 24, 2017
    Inventors: Christophe PREHAUD, Monique LAFON, Pierre-Emmanuel CECCALDI, Philippe AFONSO, Pierre LAFAYE
  • Neurovirulent strain of the West Nile virus and uses thereof
    Patent number: 9657276
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: May 23, 2017
    Assignees: Institut Pasteur, Kimron Veterinary Institute
    Inventors: Despres Philippe, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Neurovirulent Strain of the West Nile Virus and Uses Thereof
    Publication number: 20140237631
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: March 31, 2014
    Publication date: August 21, 2014
    Applicants: KIMRON VETERINARY INSTITUTE, INSTITUT PASTEUR
    Inventors: Despres Philippe, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Neurovirulent strain of the West Nile virus and uses thereof
    Patent number: 8715693
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: May 6, 2014
    Assignees: Institut Pasteur, Kimron Veterinary Institute
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Thérèse Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasséli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • NEUROVIRULENT STRAIN OF THE WEST NILE VIRUS AND USES THEREOF
    Publication number: 20120266261
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: March 16, 2012
    Publication date: October 18, 2012
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Thérèse Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasséli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • NEUROVIRULENT STRAIN OF THE WEST NILE VIRUS AND USES THEREOF
    Publication number: 20100099854
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: April 30, 2008
    Publication date: April 22, 2010
    Applicants: INSTITUT PASTEUR, KIMRON VETERINARY INSTITUTE
    Inventors: PHILIPPE DESPRES, VINCENT DEUBEL, JEAN-LOUIS GUENET, MARIE-THERESE DROUET, MERTYN MALKINSON, CAROLINE BANET, MARIE-PASCALE FRENKIEL, MARIE-PIERRE COURAGEOT, FASSELI COULIBALY, ADELINE CATTEAU, MARIE FLAMAND, PATRICK WEBER, PIERRE-EMMANUEL CECCALDI
  • Neurovirulent strain of the West Nile virus and uses thereof
    Patent number: 7390495
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: June 24, 2008
    Assignees: Institut Pasteur, Kimron Veterinary Institute
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Neurovirulent strain of the west nile virus and uses thereof
    Publication number: 20050164170
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: October 4, 2004
    Publication date: July 28, 2005
    Applicants: INSTITUT PASTEUR, KIMRON VETERINARY INSTITUTE
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi