Patents by Inventor Pierre Hamel

Pierre Hamel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5350744
    Abstract: Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
    Type: Grant
    Filed: August 27, 1992
    Date of Patent: September 27, 1994
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Yves Girard, Pierre Hamel
  • Patent number: 5314898
    Abstract: Compounds having the formula I: ##STR1## are inhibitors of the 5-lipoxygenase enzyme and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, psoriasis, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
    Type: Grant
    Filed: June 29, 1992
    Date of Patent: May 24, 1994
    Assignees: Merck & Co., Inc., Merck Frosst Canada Inc.
    Inventors: John Y. L. Chung, Robert A. Reamer, Yves Girard, Pierre Hamel
  • Patent number: 5308852
    Abstract: Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
    Type: Grant
    Filed: August 27, 1992
    Date of Patent: May 3, 1994
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Yves Girard, Daniel Delorme, Rejean Fortin, Daniel Dube, Pierre Hamel, Carol Lepine, Yves Ducharme
  • Patent number: 5252599
    Abstract: Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
    Type: Grant
    Filed: August 27, 1992
    Date of Patent: October 12, 1993
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Yves Girard, Rejean Fortin, Daniel Delorme, Daniel Dube, Pierre Hamel, Yves Ducharme, John W. Gillard
  • Patent number: 5202321
    Abstract: Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, psoriasis, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
    Type: Grant
    Filed: June 13, 1991
    Date of Patent: April 13, 1993
    Assignee: Merck Frosst Canada, Inc.
    Inventors: John H. Hutchinson, Yves Girard, Rejean Fortin, Dwight MacDonald, John Scheigetz, Daniel Delorme, Michel Therien, Pierre Hamel
  • Patent number: 5132319
    Abstract: Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
    Type: Grant
    Filed: March 28, 1991
    Date of Patent: July 21, 1992
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Yves Girard, Pierre Hamel, Daniel Delorme, Rejean Fortin
  • Patent number: 5128364
    Abstract: Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis and allograft rejection and in preventing the formation of atherosclerotic plaques.
    Type: Grant
    Filed: March 28, 1991
    Date of Patent: July 7, 1992
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Yves Girard, Pierre Hamel
  • Patent number: 5093356
    Abstract: Compounds having the formula I: ##STR1## are inhibitors of the 5-lipoxygenase enzyme. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
    Type: Grant
    Filed: January 16, 1990
    Date of Patent: March 3, 1992
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Yves Girard, Pierre Hamel, Daniel Delorme
  • Patent number: 5059031
    Abstract: A method and apparatus are described for the optical inspection of at least partially transparent objects, such as bottles or flasks, arranged in line on a moving horizontal table conveyor. A light source is located on one side of the conveyor and a linear electronic camera on the other. The camera comprises a line of photodetectors extending in a first direction. A lens forms on the camera an image of a portion of the object being inspected, the image being oriented so that as the object moves, the image moves in the same direction as the first direction. The image is scanned rapidly and repeatedly in the first direction by electronically scanning the line of photodetectors. The image is scanned in a second direction, preferably perpendicular to the first direction by a pivoting mirror which varies the portion of the object that is imaged onto the photodetectors.
    Type: Grant
    Filed: January 23, 1990
    Date of Patent: October 22, 1991
    Assignee: Saint-Gobain Cinematique et Controle
    Inventors: Jean-Pierre Hamel, Pierre Lamborot
  • Patent number: 5036067
    Abstract: Compounds having the formula I: ##STR1## are inhibitors of the 5-lipoxygenase enzyme. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.
    Type: Grant
    Filed: March 14, 1990
    Date of Patent: July 30, 1991
    Assignee: Merck & Co., Inc.
    Inventors: Yves Girard, Pierre Hamel, Daniel Delorme
  • Patent number: 4962668
    Abstract: A sensor unit is disclosed for use in monitoring in situ changes in dynamic and static stress properties of any material to be monitored, such as monolithic concrete or underground rock structures. The sensor unit includes a hollow, waterproof tubular body to be inserted into a cylindrical borehole in the material to be monitored. A transducer is mounted within the body, which by means of strain gauges, provides an output signal responsive to deflection of the sidewall of the borehole. The transducer is coupled to the sidewall by means of pressure buttons. A monitor is also disclosed, which comprises the sensor unit, a data collection unit and a data analyzing unit. A method for sensing dynamic and static changes in material stresses is also disclosed.
    Type: Grant
    Filed: May 3, 1989
    Date of Patent: October 16, 1990
    Inventors: Christoper J. Preston, John J. Cotter, John Codrington, Dimitri Frantzos, Pierre Hamel
  • Patent number: 4663307
    Abstract: Novel 6H-dibenz[b,e][1,4]oxathiepin derivatives of the Formulae I and IA are employed in the treatment and control of allergic conditions such as allergic asthma.
    Type: Grant
    Filed: October 1, 1984
    Date of Patent: May 5, 1987
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Yves Girard, Joshua Rokach, Pierre Hamel
  • Patent number: 4472586
    Abstract: Novel 6H-dibenz[b,e][1,4]oxathiepin derivatives of the formulae I and IA are employed in the treatment and control of allergic conditions such as allergic asthma.
    Type: Grant
    Filed: August 5, 1983
    Date of Patent: September 18, 1984
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Pierre Hamel, Joshua Rokach
  • Patent number: 4414415
    Abstract: (1) Process for the manufacture of 2,6-dichloro-4-nitroaniline.(2) This process consists in chlorinating paranitroaniline, with chlorine gas, in an aqueous solution of hydrochloric acid having a concentration of between 4 and 7.5 N, at the boil, at a temperature between 95.degree. and 110.degree. C.(3) This process makes it possible to obtain 2,6-dichloro-4-nitroaniline with an improved yield and an improved quality of product.
    Type: Grant
    Filed: May 13, 1981
    Date of Patent: November 8, 1983
    Assignee: Rhone-Poulenc Agrochimie
    Inventors: Michel Aubouy, Pierre Hamel, Marc Molin
  • Patent number: 4252818
    Abstract: 7-[3-(4-Acetyl-3-hydroxy-6-iodo-2-propylphenoxy)-2-hydroxypropoxy]-4-oxo-8- propyl-4H-1-benzopyran-2-carboxylic acid and its pharmaceutically acceptable salts are employed as antagonists of SRS-A (the slow reacting substance of anaphylaxis) in the treatment of asthma and allergic diseases.
    Type: Grant
    Filed: August 2, 1979
    Date of Patent: February 24, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Joshua Rokach, Pierre A. Hamel, Ralph F. Hirschmann
  • Patent number: 4237160
    Abstract: Novel 3-hydroxymethyldibenzo[b,f]thiepin and derivatives are prepared and employed in the treatment and control of allergic conditions such as allergic asthma.
    Type: Grant
    Filed: November 27, 1979
    Date of Patent: December 2, 1980
    Assignee: Merck Sharp & Dohme (I.A.) Corp.
    Inventors: Pierre A. Hamel, Joshua Rokach
  • Patent number: 3987209
    Abstract: A process for preparing flesh-containing products such as roast fowl and butcher's meat and pork-butcher's products such as hams, pies, sausages or other products, wherein pieces of raw or previously treated flesh and additive substances corresponding to the desired products are placed and enclosed under vacuum within vessels giving the desired products their final shape, the pieces of flesh, put into the vessels, undergoing a repeated vacuum action for de-aerating same.
    Type: Grant
    Filed: October 16, 1975
    Date of Patent: October 19, 1976
    Assignee: Central Properties Company Limited
    Inventors: Jacques, Andre, Gustave Gatineau, Pierre Hamel