Patents by Inventor Pieter van Rooyen

Pieter van Rooyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190181273
    Abstract: Provided herein are devices, systems, and methods of employing the same for the performance of bioinformatics analysis. The apparatuses and methods of the disclosure are directed in part to large scale graphene FET sensors, arrays, and integrated circuits employing the same for analyte measurements. The present GFET sensors, arrays, and integrated circuits may be fabricated using conventional CMOS processing techniques based on improved GFET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense GFET sensor based arrays. Improved fabrication techniques employing graphene as a reaction layer provide for rapid data acquisition from small sensors to large and dense arrays of sensors. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes, including DNA hybridization and/or sequencing reactions.
    Type: Application
    Filed: May 16, 2017
    Publication date: June 13, 2019
    Applicant: Agilome, Inc.
    Inventors: Pieter van ROOYEN, Mitchell LERNER, Paul HOFFMAN
  • Publication number: 20190171963
    Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data includes a quantum computing device formed of a set of hardwired quantum logic circuits interconnected by a plurality of superconducting connections to process information represented as a quantum state that is configured as a set of one or more qubits. The hardwired quantum logic circuits may be arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired quantum logic circuits to perform one or more steps in the bioinformatics analysis on the reads of genomic data. Each subset of the hardwired quantum logic circuits may be formed in a wired configuration to perform the one or more steps in the bioinformatics analysis.
    Type: Application
    Filed: August 31, 2018
    Publication date: June 6, 2019
    Inventor: Pieter van Rooyen
  • Publication number: 20190172552
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.
    Type: Application
    Filed: September 24, 2018
    Publication date: June 6, 2019
    Inventors: Pieter van Rooyen, Michael Ruehle, Robert McMillen
  • Publication number: 20190172558
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.
    Type: Application
    Filed: August 31, 2018
    Publication date: June 6, 2019
    Inventors: Pieter van Rooyen, Robert McMillen, Michael Ruehle
  • Publication number: 20190147981
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes an integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. In various instances, each subset of the hardwired digital logic circuits may be formed in a wired configuration to perform one or more steps a variant call operation.
    Type: Application
    Filed: August 31, 2018
    Publication date: May 16, 2019
    Inventors: Pieter van Rooyen, Michael Ruehle, Robert McMillen, Mark Hahm
  • Publication number: 20190130998
    Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data is provided. Particularly, a genomics analysis platform for executing a sequence analysis pipeline is provided. The genomics analysis platform includes one or more of a first integrated circuit, where each first integrated circuit forms a central processing unit (CPU) that is responsive to one or more software algorithms that are configured to instruct the CPU to perform a first set of genomic processing steps of the sequence analysis pipeline.
    Type: Application
    Filed: August 31, 2018
    Publication date: May 2, 2019
    Inventors: Pieter van Rooyen, Michael Ruehle, Rami Mehio, Gavin Stone, Mark Hahm, Eric Ojard, Amnon Ptashek
  • Patent number: 10262105
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: April 16, 2019
    Assignee: EDICO GENOME, CORP.
    Inventors: Pieter van Rooyen, Robert J. McMillen, Michael Ruehle
  • Patent number: 10216898
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: February 26, 2019
    Assignee: Edico Genome Corporation
    Inventors: Robert J. McMillen, Pieter van Rooyen, Michael Ruehle
  • Patent number: 10210308
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: February 19, 2019
    Assignee: Edico Genome Corporation
    Inventors: Pieter van Rooyen, Michael Ruehle, Robert J. McMillen
  • Patent number: 10083276
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: September 25, 2018
    Assignee: Edico Genome, Corp.
    Inventors: Pieter van Rooyen, Michael Ruehle, Robert J. Mcmillen
  • Patent number: 10068052
    Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data is provided. Particularly, a genomics analysis platform for executing a sequence analysis pipeline is provided. The genomics analysis platform includes one or more of a first integrated circuit, where each first integrated circuit forms a central processing unit (CPU) that is responsive to one or more software algorithms that are configured to instruct the CPU to perform a first set of genomic processing steps of the sequence analysis pipeline.
    Type: Grant
    Filed: February 27, 2018
    Date of Patent: September 4, 2018
    Assignee: Edico Genome Corporation
    Inventors: Pieter van Rooyen, Michael Ruehle, Rami Mehio, Gavin Stone, Mark David Hahm, Eric Ojard, Amnon Ptashek
  • Patent number: 10068055
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: September 4, 2018
    Assignee: EDICO GENOME CORP.
    Inventors: Pieter van Rooyen, Robert J. McMillen, Michael Ruehle
  • Patent number: 10068054
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes an integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. In various instances, each subset of the hardwired digital logic circuits may be formed in a wired configuration to perform one or more steps a variant call operation.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: September 4, 2018
    Assignee: EDICO GENOME, CORP.
    Inventors: Pieter Van Rooyen, Michael Ruehle, Robert J. Mcmillen, Mark Hahm
  • Patent number: 10068183
    Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data includes a quantum computing device formed of a set of hardwired quantum logic circuits interconnected by a plurality of superconducting connections to process information represented as a quantum state that is configured as a set of one or more qubits. The hardwired quantum logic circuits may be arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired quantum logic circuits to perform one or more steps in the bioinformatics analysis on the reads of genomic data. Each subset of the hardwired quantum logic circuits may be formed in a wired configuration to perform the one or more steps in the bioinformatics analysis.
    Type: Grant
    Filed: April 25, 2017
    Date of Patent: September 4, 2018
    Assignee: EDICO GENOME, CORP.
    Inventor: Pieter van Rooyen
  • Publication number: 20180240032
    Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data includes a quantum computing device formed of a set of hardwired quantum logic circuits interconnected by a plurality of superconducting connections to process information represented as a quantum state that is configured as a set of one or more qubits. The hardwired quantum logic circuits may be arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired quantum logic circuits to perform one or more steps in the bioinformatics analysis on the reads of genomic data. Each subset of the hardwired quantum logic circuits may be formed in a wired configuration to perform the one or more steps in the bioinformatics analysis.
    Type: Application
    Filed: April 25, 2017
    Publication date: August 23, 2018
    Inventor: Pieter van Rooyen
  • Publication number: 20180239865
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.
    Type: Application
    Filed: April 23, 2018
    Publication date: August 23, 2018
    Inventors: Pieter van Rooyen, Michael Ruehle, Robert J. McMillen
  • Patent number: 10049179
    Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data is provided. Particularly, a genomics analysis platform for executing a sequence analysis pipeline is provided. The genomics analysis platform includes one or more of a first integrated circuit, where each first integrated circuit forms a central processing unit (CPU) that is responsive to one or more software algorithms that are configured to instruct the CPU to perform a first set of genomic processing steps of the sequence analysis pipeline.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: August 14, 2018
    Assignee: EDICO GENOME, CORP.
    Inventors: Pieter van Rooyen, Michael Ruehle, Rami Mehio, Gavin Stone, Mark Hahm, Eric Ojard, Amnon Ptashek
  • Publication number: 20180196916
    Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data is provided. Particularly, a genomics analysis platform for executing a sequence analysis pipeline is provided. The genomics analysis platform includes one or more of a first integrated circuit, where each first integrated circuit forms a central processing unit (CPU) that is responsive to one or more software algorithms that are configured to instruct the CPU to perform a first set of genomic processing steps of the sequence analysis pipeline.
    Type: Application
    Filed: March 7, 2018
    Publication date: July 12, 2018
    Inventors: Pieter van Rooyen, Michael Ruehle, Rami Mehio, Gavin Stone, Mark David Hahm, Eric Ojard, Amnon Ptashek
  • Publication number: 20180196917
    Abstract: A system, method and apparatus for executing a sequence analysis pipeline on genetic sequence data includes a structured ASIC formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the structured ASIC connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits are arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the sequence analysis pipeline on the reads of genomic data. Each subset of the hardwired digital logic circuits is formed in a wired configuration to perform the one or more steps in the sequence analysis pipeline.
    Type: Application
    Filed: March 8, 2018
    Publication date: July 12, 2018
    Inventors: Pieter van Rooyen, Robert J. McMillen, Michael Ruehle
  • Publication number: 20180189444
    Abstract: A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data is provided. Particularly, a genomics analysis platform for executing a sequence analysis pipeline is provided. The genomics analysis platform includes one or more of a first integrated circuit, where each first integrated circuit forms a central processing unit (CPU) that is responsive to one or more software algorithms that are configured to instruct the CPU to perform a first set of genomic processing steps of the sequence analysis pipeline.
    Type: Application
    Filed: February 27, 2018
    Publication date: July 5, 2018
    Inventors: Pieter van Rooyen, Michael Ruehle, Rami Mehio, Gavin Stone, Mark David Hahm, Eric Ojard, Amnon Ptashek