Abstract: Provided are methods of treating or preventing Ca2+/calmodulin-dependent kinase II (CaMKII)-mediated diseases, methods of alleviating cardiac injury, methods of stimulating the activity of ubiquitin-conjugating enzyme, methods of preventing degradation of ubiquitin-conjugating enzyme, methods of preventing cardiomyocyte death, methods of reducing DNA damage in a cell, methods for diagnosing CaMKII-mediated diseases, kits for diagnosing CaMKII-mediated diseases, biomarkers for diagnosing a CaMKII-mediated disease, and use of CaMKII?9 as a biomarker for diagnosing a CaMKII-mediated disease. Also provided herein are methods for identifying molecules, isolated polypeptides, isolated nucleic acids, and antagonists thereof.

Abstract: A processor initiates a run of a target container in a distributed computing environment. A processor detects at least one error occurring during the initiation of the target container. A processor determines at least one fix image based on the at least one error. A processor performs an error recovery of the target container based on the at least one fix image. A processor runs, in response to successfully performing the error recovery of the target container, the target container in the distributed computing environment.

Abstract: A heat pipe operating noiselessly by preventing, or reducing the effects of, the mixing of working fluid at different temperatures includes a hollow tube, a capillary structure, a working fluid, and a bushing. The porous capillary structure able to carry the fluid is disposed on an inner wall of the tube. The bushing is hollow, and the bushing is disposed on a surface of the capillary structure away from the tube. The heat pipe is divided into evaporation, adiabatic, and condensation sections, the capillary structure being at all sections. The working fluid is disposed in the capillary structure of the evaporation section, the bushing is disposed on a side of the capillary structure of the adiabatic section.

Abstract: A processor may receive a recording. The recording may include one or more user guidance sequences and be displayed to a user. The processor may receive a first user input response to an initiation of a first user guidance sequence. The processor may determine, in response to receiving the first user input, that there is a discrepancy between the first user input and the first user guidance sequence. The processor may automatically modify the playback setting of the recording. The processor may display the discrepancy between the first user input and the first user guidance sequence to the user.

Abstract: In an approach, a processor detects at least one training message delivered by a user on a social media application, the training message being accessible by an operator. A processor records training feedback performed by the operator on the social media application regarding to the at least one training message. A processor trains an analysis engine module using (i) the at least one training message as input and (ii) the training feedback as output. A processor generates a predicted feedback for a subsequent message based on the trained analysis engine module.

Abstract: Method and system are provided for audio quality feedback during live transmission from a source that is received at multiple audience devices. The method carried out at a server includes: obtaining audio information of an audio signal as received by at least some of the audience devices in a transmission session; classifying one or more subsets of the audience devices by one or more common factors per subset; and analyzing the obtained audio information from the audience devices in conjunction with the classifications of the subsets of the audience devices to determine one or more common factors that affect received audio quality at an identified subset of the audience devices classified by the one or more common factors. The method provides feedback of the one or more common factors to at least one of the audience devices in the identified subset or to the source device, or to both.

Abstract: The present invention relates to an MG53 mutant, wherein the MG53 mutant is identical to the amino acid sequence of a wild-type MG53 except for at least one serine in the coiled-coil-SPRY region of the wild-type MG53, which is deleted and/or mutated into any other non-serine or non-threonine amino acid(s). The present invention also relates to a pharmaceutical composition comprising the MG53 mutant, a nucleic acid encoding the MG53 mutant, a method for preparing the MG53 mutant, use of the MG53 mutant in the manufacture of a medicament for treating heart diseases, diabetic cerebrovascular diseases, diabetic ocular complications, diabetic neuropathy, diabetic foot, kidney diseases, and diseases associated with cellular and/or tissue damage. In particular, the MG53 mutant of the present invention may avoid or reduce metabolic side effects, such as, insulin resistance, obesity, diabetes, hypertension, dyslipidemia, etc.

Abstract: Provided is a method for desulphurizating and denitrating a flue gas in an integrated manner based on low-temperature adsorption. The method includes: decreasing a temperature of the flue gas below a room temperature by using a flue gas cooling system; removing moisture in the flue gas by using a dehumidification system; sending the flue gas to a SO2 and NOx adsorbing column system; and simultaneously adsorbing SO2 and NOx of the flue gas with a material of activated coke, activated carbon, a molecular sieve or diatom mud in the SO2 and NOx adsorbing column system to implement an integration of desulphurization and denitration of the flue gas based on the low-temperature adsorption. With the present method, SO2 and NOx of the flue gas can be adsorbed simultaneously in an environment having a temperature below the room temperature.

Abstract: A processor initiates a run of a target container in a distributed computing environment. A processor detects at least one error occurring during the initiation of the target container. A processor determines at least one fix image based on the at least one error. A processor performs an error recovery of the target container based on the at least one fix image. A processor runs, in response to successfully performing the error recovery of the target container, the target container in the distributed computing environment.

Abstract: Aspects of the invention include determining artifact data associated with an artifact, segmenting the artifact data into a plurality of portions, associating each portion in the plurality of portions with one or more resources, receiving a query associated with the artifact, determining a candidate resource from the one or more resources based on the query, and initializing a communication session with the candidate resource and a requesting application associated with the query.

Abstract: Disclosed is a flue gas low-temperature adsorption denitration system and process. The system includes a booster fan, a cold energy recoverer, a flue gas cooling system, a flue gas switching valve, and two denitration adsorption towers. An inlet of the booster fan is in communication with an inlet flue gas pipeline. The booster fan, the cold energy recoverer, the flue gas cooling system, the flue gas switching valve, and the denitration adsorption towers are sequentially communicated. An outlet of the flue gas switching valve is in communication with each of the two second denitration adsorption towers. Flue gas outlets of the two denitration adsorption towers are in communication with a flue gas manifold. The flue gas manifold is communicated with the cold quantity recoverer. Two denitration adsorption towers take turns to carry out denitration and regeneration processes, so that continuous denitration operations of the system can be achieved.

Abstract: Embodiments of the present invention provide methods, computer program products, and systems. Embodiments of the present invention can receive an application processing interface (API) invoke request for a service to be directed to an API management device. Embodiments of the present invention can then determine that there is a fast path to a service provider for the service requested by the API invoke request according to a fast path record in an accelerator. Embodiments of the present invention can then send the API invoke request to the service provider through the fast path based on the service provider's connection information.

Abstract: A system, computer-implemented method, and computer program product for demonstrating a software application on a computer. The system includes a capture component running in a presenter environment and an invoker component running in a viewer environment. One or more steps performed by a presenter on a first copy of a software application being run in the presenter environment are recorded at the capture component. The invoker component access the one or more steps and performs the one or more steps on a second copy of the software application being run in the viewer environment.

Abstract: The present invention discloses a flue gas low-temperature adsorption denitrification method, including: pressurizing a flue gas that has been subjected to dust removal and desulfurization, precooling the pressurized flue gas, cooling the precooled flue gas to a temperature lower than room temperature by a flue gas cooling system, flowing the flue gas at the temperature lower than room temperature into a low-temperature denitrification system, performing physical adsorption denitrification in the low-temperature denitrification system, precooling the flue gas that has been subjected to dust removal and desulfurization with the denitrificated flue gas, and flowing the heat-absorbed clean flue gas into a chimney to be discharged.

Abstract: Aspects of the invention include determining artifact data associated with an artifact, segmenting the artifact data into a plurality of portions, associating each portion in the plurality of portions with one or more resources, receiving a query associated with the artifact, determining a candidate resource from the one or more resources based on the query, and initializing a communication session with the candidate resource and a requesting application associated with the query.

Abstract: In an approach, a processor detects at least one training message delivered by a user on a social media application, the training message being accessible by an operator. A processor records training feedback performed by the operator on the social media application regarding to the at least one training message. A processor trains an analysis engine module using (i) the at least one training message as input and (ii) the training feedback as output. A processor generates a predicted feedback for a subsequent message based on the trained analysis engine module.

Abstract: Embodiments of the invention provide methods, systems, computer program products for managing a call waiting in a queue during a request for staff services provided by a call center. According to the method, a first voice segment received in a call made by a device is recorded first. Next, whether a part of the first voice segment is related to a first predefined voice segment is determined. The volume of device is adjusted in response to the part of the first voice segment being related to the first predefined voice segment. A user of the device is alerted in response to the part of the first voice segment being not related to the first predefined voice segment.

Abstract: A file is transmitted to a plurality of hosts. The hosts are divided into host groups. A host in each host group is selected as a master host. A data block is received by a master host in a host group. The master host sends the data block to both a master host in a next host group and a next host in the host group in order that the next host in the host group sends the data block to a next host of the next host in the host group, and the master host in the next host group sends the data block to both a master host in a next host group of the next host group and a next host of the next host in the next host group.

Abstract: Embodiments of the present disclosure relate to a method for building an application. According to the method, a request is received from a building environment to acquire at least one component for executing at least one function of at least one feature of the application. The at least one feature is to be deployed to at least one target node in a distributed service platform comprising a plurality of nodes. The at least one target node and the at least one component are determined based on the request. The at least one component is acquired from the at least one target node. The at least one component is sent to the building environment for building the at least one feature.