Patents by Inventor Piotr Kowalczyk

Piotr Kowalczyk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210216668
    Abstract: An example operation may include one or more of detecting a web session within an open window of a web browser on a user device, monitoring for user activity on the user device with respect to the web browser, determining there has been a lack of user activity with respect to the web browser for a predetermined amount of time based on the monitoring of the user activity, and temporarily concealing content within the open window of the web browser in response to the lack of user activity.
    Type: Application
    Filed: January 10, 2020
    Publication date: July 15, 2021
    Inventors: PIOTR P. GODOWSKI, Michal Paluch, Tomasz Hanusiak, Szymon Kowalczyk
  • Publication number: 20200131141
    Abstract: The present disclosure relates to compounds of Formula (I): and to their pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. The compounds disclosed herein inhibit the maturation of cytokines of the IL-1 family by inhibiting inflammasomes and may be used in the treatment of disorders in which inflammasome activity is implicated, such as inter alia autoinflammatory and autoimmune diseases and cancers.
    Type: Application
    Filed: March 12, 2018
    Publication date: April 30, 2020
    Inventors: David HARRISON, Alan Paul WATT, Nicolas BOUTARD, Charles-Henry FABRITIUS, Michal GALEZOWSKI, Piotr KOWALCZYK, Oleksandr LEVENETS, Jakub WOYCIECHOWSKI
  • Patent number: 8393528
    Abstract: A method for hardfacing a metal component surface (14, 16), especially a shroud surface of a turbine blade made of a TiAl alloy, with at least one metal material (18, 20), in particular a Co—Cr alloy. The hardfacing coating is produced separately from the component surface and is then joined to the component surface in a high-temperature soldering process. A turbine blade including such a hardfacing coating, primarily in a shroud region (2).
    Type: Grant
    Filed: July 8, 2010
    Date of Patent: March 12, 2013
    Assignee: MTU Aero Engines GmbH
    Inventors: Karl-Hermann Richter, Ulrich Knott, Piotr Kowalczyk
  • Publication number: 20120125980
    Abstract: A method for hardfacing a metal component surface (14, 16), especially a shroud surface of a turbine blade made of a TiAl alloy, with at least one metal material (18, 20), in particular a Co—Cr alloy. The hardfacing coating is produced separately from the component surface and is then joined to the component surface in a high-temperature soldering process. A turbine blade including such a hardfacing coating, primarily in a shroud region (2).
    Type: Application
    Filed: July 8, 2010
    Publication date: May 24, 2012
    Applicant: MTU Aero Engines GmbH
    Inventors: Karl-Hermann Richter, Ulrich Knott, Piotr Kowalczyk
  • Patent number: 7629370
    Abstract: The invention relates to a method of treatment and/or prophylaxis of diseases and conditions mediated by peroxysome proliferator-activated receptor gamma (PPAR?) in a mammal subject in need thereof, said method comprising administration to said mammal a compound of formula (I) or a pharmaceutically acceptable salt thereof in a therapeutically or prophylactically effective amount wherein in formula (I) W represents a COOH group or its bioisosters, or COO—C1-C4-alkyl group; Y represents NH or N—C1-C10-alkyl; Z represents NH, N—C1-C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C1-C10-alkyl, N-aryl, NSO2—C1-C10-alkyl, N—SO2-aryl, or N S02-heteroaryl; R1 to R6 each independently represents a hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive. The compounds of formula (I) are the ligands of PPAR-gamma receptor.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: December 8, 2009
    Assignee: Adamed Sp. z o.o.
    Inventors: Zbigniew Majka, Katarzyna Ewa Rusin, Dominik Daniel Kludkiewicz, Krzysztof Kurowski, Katarzyna Joanna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski, Piotr Kowalczyk
  • Patent number: 7312338
    Abstract: The invention relates to new compounds, being 3-phenylpropionic acid derivatives of formula I wherein W represents COOH group or its bioisosters, or —COO—C1-C4-alkyl group; Y represents NH, N—C1-C10-alkyl, O, or S; Z represents NH, N—C1-C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C1-C10-alkyl, N-aryl, NSO2—C1-C10-alkyl, N—SO2-aryl, or N—SO2-heteroaryl; R1 to R8 each independently represent hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: December 25, 2007
    Assignee: Adamed, Sp. z.o.o.
    Inventors: Zbigniew Majka, Katarzyna Ewa Rusin, Andrzej Wojciech Sawicki, Krzysztof Kurowski, Katarzyna Joanna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski, Piotr Kowalczyk
  • Patent number: 7309791
    Abstract: The invention relates to new compounds, being 3-phenylpropionic acid derivatives of formula I wherein W represents COOH group or its bioisosters, or —COO—C1–C4-alkyl group; Y represents NH, N—C1–C10-alkyl, O, or S; Z represents NH, N—C1–C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C1–C10-alkyl, N-aryl, NSO2—C1–C10-alkyl, N—SO2-aryl, or N—SO2-heteroaryl; R1, to R6 each independently represent hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof. The compounds are the ligands of PPAR-gamma receptor and are useful as medicaments.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: December 18, 2007
    Assignee: Adamed Sp. z.o.o
    Inventors: Zbigniew Majka, Katarzyna Ewa Rusin, Dominik Daniel Kludkiewicz, Krzysztof Kurowski, Katarzyna Joanna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski, Piotr Kowalczyk
  • Publication number: 20070161799
    Abstract: The invention relates to a method of treatment and/or prophylaxis of diseases and conditions mediated by peroxysome proliferator-activated receptor gamma (PPAR?) in a mammal subject in need thereof, said method comprising administration to said mammal a compound of formula (I) or a pharmaceutically acceptable salt thereof in a therapeutically or prophylactically effective amount wherein in formula (I) W represents a COOH group or its bioisosters, or COO—C1-C4-alkyl group; Y represents NH or N—C1-C10-alkyl; Z represents NH, N—C1-C10-alkyl, N-aryl, N-heteroaryl, S, or O; X represents O, S, NH, N—C1-C10-alkyl, N-aryl, NSO2—C1-C10-alkyl, N—SO2-aryl, or N S02-heteroaryl; R1 to R6 each independently represents a hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive. The compounds of formula (I) are the ligands of PPAR-gamma receptor.
    Type: Application
    Filed: March 6, 2007
    Publication date: July 12, 2007
    Applicant: ADAMED, Sp. z o.o.
    Inventors: Zbigniew Majka, Katarzyna Rusin, Dominik Kludkiewicz, Krzysztof Kurowski, Katarzyna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski, Piotr Kowalczyk
  • Patent number: 7220766
    Abstract: The invention relates to new compounds, 3-phenylpropionic acid derivatives of formula (I) wherein W represents COOH group or its bioisosters, or —COO—C1–C4-alkyl group; Y represents NH, N—C1–C10-alkyl, O, or S; X represents O, S, NH, N—C1–C10-alkyl, N-aryl, NSO2—C1–C10-alkyl, N—SO2-aryl, or N—SO2-heteroaryl; R1 to R8 each independently represents hydrogen atom or a substituent defined in the description; A is as defined in the description; n represents an integer from 0 to 4, inclusive; and pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: May 22, 2007
    Assignee: ADAMED, Sp. z.o.o.
    Inventors: Zbigniew Majka, Katarzyna Ewa Rusin, Andrzej Wojciech Sawicki, Krzysztof Kurowski, Katarzyna Joanna Matusiewicz, Tomasz Stawinski, Daniel Sulikowski, Dominik Daniel Kludkiewicz, Piotr Kowalczyk