Patents by Inventor Pramod Narayan Deshpande

Pramod Narayan Deshpande has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF BETA-LACTAM ANTIBIOTIC
    Publication number: 20120095210
    Abstract: The present invention provides a novel process for the preparation of the meropenem trihydrate of formula (I).
    Type: Application
    Filed: December 29, 2011
    Publication date: April 19, 2012
    Applicant: ORCHID CHEMICALS & PHARMACEUTICALS LIMITED
    Inventors: Senthilkumar SURULICHAMY, Selvakumar SEKAR, Pramod Narayan DESHPANDE, Panchapakesan GANPATHY, Rajendra Janardan SARANGDHAR, Syril Sudhan HENRY, Sanjay Nivruti KARALE, Arvind Atmaram JANGALE, Ram Dattatray KALDATE
  • Process for the preparation of beta-lactam antibiotic meropenem trihydrate
    Patent number: 8148520
    Abstract: A process for preparing purified Meropenem trihydrate that involves the dissolution of Meropenem in water in presence of base, adjusting the pH to 4.0-7.0, and adding solvent to yield Meropenem trihydrate.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: April 3, 2012
    Assignee: Orchid Chemicals and Pharmaceuticals Limited
    Inventors: Senthilkumar Surulichamy, Selvakumar Sekar, Pramod Narayan Deshpande, Panchapakesan Ganpathy, Rajendra Janardan Sarangdhar, Syril Sudhan Henry, Sanjay Nivruti Karale, Arvind Atmaram Jangale, Ram Dattatray Kaldate
  • Process for The Preparation of Beta-Lactam Antibiotic
    Publication number: 20090264643
    Abstract: The present invention relates to a process for the preparation of Meropenem of formula (I) in sterile form and also provides an improved process for the preparation of compound of formula (V), which is an important intermediate in the synthesis of Meropenem.
    Type: Application
    Filed: September 15, 2006
    Publication date: October 22, 2009
    Inventors: Senthilkumar Surulichamy, Selvakumar Sekar, Pramod Narayan Deshpande, Panchapakesan Ganpathy, Rajendra Janardan Sarangdhar, Syril Sudhan Henry, Sanjay Nivruti Karale, Arvind Atmaram Jangale, Ram Dattatray Kaldate
  • Synthesis of ceftiofur intermediate
    Patent number: 6803461
    Abstract: The present invention relates to a process for preparation of 7-amino-3-[2-(furylcarbonyl)thiomethyl]-3-cephem-4-carboxylic acid (I) by the condensation of 7-aminocephalosporanic acid (II) with furyl-2-carbonylthiol (III) in the presence of borontrifluoride or its complex, in an organic solvent or mixture of solvents at 0-50° C.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: October 12, 2004
    Assignee: Orchid Chemicals and Pharmaceuticals Limited
    Inventors: Pramod Narayan Deshpande, Bhausaheb Pandharinath Khadangale, Surulichamy Senthil Kumar, Gautam Kumar Das
  • Process for the preparation of cefixime
    Patent number: 6800755
    Abstract: The present invention provides an improved process for the preparation of cefixime of formula (I), with an improved quality having/possessing better color and solubility: the process includes the steps of dissolving the compound of formula (II) in water/water immisible solvent using sodium bicarbonate at a temperature in the range of 0° C. to the 35° C., hydrolyzing with sodium hydroxide at a temperature in the range of 0° C. to 25° C., and acidifying the resultant mass to 2.3 to 3.0 with dilute acid in the presence or absence of solvent at a temperature in the range of 10° C. to 45° C.
    Type: Grant
    Filed: December 5, 2002
    Date of Patent: October 5, 2004
    Assignee: Orchid Chemicals and Pharmaceuticals Limited
    Inventors: Pandurang Balwant Deshpande, Gautam Kumar Das, Pramod Narayan Deshpande, Ramasubbu Chandrasekaran, Padmanabhan Ramar, John Muthiah Raja Jeyakumar
  • Process for the preparation of cefuroxime sodium
    Publication number: 20040092735
    Abstract: The present invention relates to an improved process for the preparation of the sterile cefuroxime sodium of formula (I).
    Type: Application
    Filed: December 5, 2002
    Publication date: May 13, 2004
    Applicant: Orchid Chemicals & Pharmaceuticals Limited
    Inventors: Pandurang Balwant Deshpande, Pramod Narayan Deshpande, Bhausaheb Pandharinath Khadangale, Gautam Kumar Das, John Muthiah Raja Jeyakumar
  • Process for the preparation of cefixime
    Publication number: 20040082560
    Abstract: The present invention provides an improved process for the preparation of cefixime of formula (I), with an improved quality having/possessing better color and solubility.
    Type: Application
    Filed: December 5, 2002
    Publication date: April 29, 2004
    Applicant: ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED
    Inventors: Pandurang Balwant Deshpande, Gautam Kumar Das, Pramod Narayan Deshpande, Ramasubbu Chandrasekaran, Padmanabhan Ramar, John Muthiah Raja Jeyakumar
  • Process for the preparation of cefadroxil
    Publication number: 20040077849
    Abstract: The present invention relates to an improved process for the preparation of cefadroxil of the formula (I), more particularly, the present invention relates to an improved process for the preparation of cefadroxil having water content in the range of 4-5%.
    Type: Application
    Filed: December 5, 2002
    Publication date: April 22, 2004
    Applicant: Orchid Chemicals & Pharmaceuticals Limited
    Inventors: Pramod Narayan Deshpande, Gautam Kumar Das, Rajendra Janardan Sarangdhar, Peter Xavier Tharial
  • Thioester derivatives of thiazolyl acetic acid and their use in the preparation of cephalosporin compounds
    Patent number: 6610845
    Abstract: The present invention provides new thioester derivatives of thiazolyl acetic acid of the general formula (I), wherein, R1 represents H, trityl, CH3, CRaRbCOOR2 (Ra and Rb independently of one another represents hydrogen or methyl and R2 represents H or C1-C4 alkyl). also, the invention provides a method by which the said thioester derivatives can be prepared by reacting thiazolyl acetic acid of the general formula (IV) with 1,2,5,6 tetrahdro-2-methyl-5,6 dioxo-1,2,4-triazin-3-thiol of the formula (VI) in a solvent, in presence of an organic base and with the help of Vilsmeier reagent of the formula (V). The so obtained thioester derivatives are reacted with 7-amino-cephem carboxylic acids of the general formula (III) to produce cephalosporin antibiotic compounds having the general formula (II).
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: August 26, 2003
    Assignee: Orchid Chemicals & Pharmaceuticals Limited, India
    Inventors: Pandurang Balwant Deshpande, Pramod Narayan Deshpande, Shanmugam Srinivasan, Parven Kumar Luthra, Gautam Kumar Das
  • Synthesis of ceftiofur intermediate
    Publication number: 20030135041
    Abstract: The present invention provides an improved process for the preparation of 7-amino-3-[2-(furylcarbonyl)thiomethyl]-3-cephem-4-carboxylic acid represented by formula (I) 1
    Type: Application
    Filed: January 4, 2002
    Publication date: July 17, 2003
    Applicant: ORCHID CHEMICALS & PHARMACEUTICALS LIMITED, INDIA
    Inventors: Pramod Narayan Deshpande, Bhausaheb Pandharinath Khadangale, Surulichamy Senthil Kumar, Gautam Kumar Das
  • Synthesis of ceftiofur intermediate
    Publication number: 20030130502
    Abstract: The present invention relates to a process for preparation of 7-amino-3-[2-(furylcarbonyl)thiomethyl]-3-cephem-4-carboxylic acid (I) by the condensation of 7-aminocephalosporanic acid (II) with furyl-2-carbonylthiol (III) in the presence of borontrifluoride or its complex, in an organic solvent or mixture of solvents at 0-50° C.
    Type: Application
    Filed: August 1, 2002
    Publication date: July 10, 2003
    Applicant: Orchid Chemicals and Pharmaceuticals Limited
    Inventors: Pramod Narayan Deshpande, Bhausaheb Pandharinath Khadangale, Surulichamy Senthil Kumar, Gautam Kumar Das
  • Method for the preparation of ceftiofur sodium
    Patent number: 6555680
    Abstract: The present invention relates to a process for the preparation of sodium salt of Ceftiofur as given in Formula I, directly from its amine salt using sodium base.
    Type: Grant
    Filed: December 10, 2001
    Date of Patent: April 29, 2003
    Assignee: Orchid Chemicals & Pharmaceuticals Ltd.
    Inventors: Pandurang Balwant Deshpande, Pramod Narayan Deshpande, Milind Ramkrishna Kulkarni, Parven Kumar Luthra