Patents by Inventor PURDUE RESEARCH FOUNDATION
PURDUE RESEARCH FOUNDATION has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180351065Abstract: Lanthanum strontium manganate (La0.67Sr0.33MnO3, i.e., LSMO)/lanthanum manganate (LaMnO3, i.e., LMO) perovskite oxide metal/semiconductor superlattices were investigated for potential p-type thermoelectric applications. Growth optimizations were performed using pulsed laser deposition to achieve epitaxial superlattices of LSMO (metal)/LMO (p-type semiconductor) on strontium titanate (STO) substrates. The cross-plane Seebeck coefficient of the thermoelectric superlattice measured between the substrate and the capping layer has a value of at least 1600 ?V/K measured at about 300K.Type: ApplicationFiled: March 15, 2013Publication date: December 6, 2018Inventor: Purdue Research Foundation
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Publication number: 20150143913Abstract: Apparatuses and methods for detecting hidden or modified objects in a vehicle are disclosed. Embodiments include detection of vehicle irregularities, such as irregularities in the acoustical response of a vehicle tire as the tire rolls over a surface, irregularities in the orientation of the vehicle body, the response of a vehicle component (such as an axle, wheel, tire, etc.) to the vehicle moving over a surface, and the response of a vehicle component to vehicle generated vibrations. In alternate embodiments subsystems detecting different irregularities communicate with one another.Type: ApplicationFiled: January 22, 2013Publication date: May 28, 2015Applicant: Purdue Research FoundationInventor: Purdue Research Foundation
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Publication number: 20140261604Abstract: Lanthanum strontium manganate (La0.67Sr0.33MnO3, i.e., LSMO)/lanthanum manganate (LaMnO3, i.e., LMO) perovskite oxide metal/semiconductor superlattices were investigated for potential p-type thermoelectric applications. Growth optimizations were performed using pulsed laser deposition to achieve epitaxial superlattices of LSMO (metal)/LMO (p-type semiconductor) on strontium titanate (STO) substrates. The cross-plane Seebeck coefficient of the thermoelectric superlattice measured between the substrate and the capping layer has a value of at least 1600 ?V/K measured at about 300K.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventor: Purdue Research Foundation
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Publication number: 20140112413Abstract: A code word selection method performed by a User Equipment (UE) in a wireless communication system is provided. The method includes generating a rotation matrix using previously selected codeword; generating a new differential code book using the rotation matrix and a differential code book; selecting a code word from the new differential code book; and performing data transmission using the selected code word.Type: ApplicationFiled: October 19, 2012Publication date: April 24, 2014Applicants: Purdue Research Foundation, Samsung Electronics Co., Ltd.Inventors: Samsung Electronics Co., Ltd., Purdue Research Foundation
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Publication number: 20140073763Abstract: Described herein are prostate specific membrane antigen (PSMA) binding conjugates that are useful for delivering therapeutic, diagnostic and imaging agents. Also described herein are pharmaceutical composition containing them and methods of using the conjugates and compositions. Also described are processes for manufacture of the conjugates and the compositions containing them.Type: ApplicationFiled: March 14, 2013Publication date: March 13, 2014Applicant: PURDUE RESEARCH FOUNDATIONInventor: Purdue Research Foundation
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Publication number: 20140065066Abstract: The invention relates to a method of treating or diagnosing a disease state mediated by monocytes. The method utilizes a composition comprising a conjugate or complex of the general formula Ab-X wherein the group Ab comprises a ligand that binds to monocytes, and when the conjugate is being used for treatment of the disease state, the group X comprises an immunogen, a cytotoxin, or a compound capable of altering monocyte function, and when the conjugate is being used for diagnosing the disease state, the group X comprises an imaging agent.Type: ApplicationFiled: March 11, 2013Publication date: March 6, 2014Applicant: PURDUE RESEARCH FOUNDATIONInventor: PURDUE RESEARCH FOUNDATION
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Publication number: 20140056809Abstract: The invention relates to a method of treating or monitoring/diagnosing a disease state mediated by activated macrophages. The method comprises the step of administering to a patient suffering from a macrophage mediated disease state an effective amount of a composition comprising a conjugate or complex of the general formula Ab-X where the group Ab comprises a ligand capable of binding to activated macrophages, and when the conjugate is being used for treatment of the disease state, the group X comprises an immunogen, a cytotoxin, or a compound capable of altering macrophage function, and when the conjugate is being used for monitoring/diagnosing the disease state, X comprises an imaging agent. The method is useful for treating a patient suffering from a disease selected from the group consisting of rheumatoid arthritis, ulcerative colitis, Crohn's disease, inflammation, infections, osteomyelitis, atherosclerosis, organ transplant rejection, pulmonary fibrosis, sarcoidosis, and systemic sclerosis.Type: ApplicationFiled: March 12, 2013Publication date: February 27, 2014Applicant: PURDUE RESEARCH FOUNDATIONInventor: Purdue Research Foundation
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Publication number: 20130330782Abstract: Described are processes that include the non-enzymatic, hydrolytic liquefaction of lignocellulosic biomass to form digest slurries and heat recovery from such digest slurries. Due to enhanced flow properties of the digest slurries such heat recovery can be efficiently conducted in spiral, plate and frame or other heat exchanger designs, with the recovered heat going to unit operations of the process such as heating incoming pretreatment media for the liquefaction. Processes can also involve additional hydrolytic digestion of some or all of the initial slurry components with enzyme and/or additional heat recovery from the initial slurry by direct contact heat exchange in which a portion of the digest slurry liquids is flashed to vapor and that vapor is condensed onto incoming lignocellulosic biomass to the process. Processes as described can be integrated into ethanol manufacture by fermentation of sugars from the digested compositions.Type: ApplicationFiled: July 29, 2011Publication date: December 12, 2013Applicant: Purdue Research FoundationInventor: Purdue Research Foundation
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Publication number: 20130307626Abstract: Illustrative embodiments of power amplifiers and associated methods are disclosed. In at least one embodiment, a method may include fabricating a power amplifier in a first silicon layer of a silicon-on-insulator (SOI) substrate, wherein the SOI substrate comprises the first silicon layer, a second silicon layer, and a buried oxide layer disposed between the first and second silicon layers; removing at least some of the second silicon layer from the SOI substrate, after fabricating the power amplifier; and securing the SOI substrate, after removing at least some of the second silicon layer, to an electrically non-conductive and thermally conductive substrate.Type: ApplicationFiled: March 12, 2013Publication date: November 21, 2013Inventor: Purdue Research Foundation
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Publication number: 20130226469Abstract: Systems, methods, and computer-readable media for determining parameters are provided, as are methods for determining differences in one or more biological response(s) by cell(s) to factor(s). Distances or difference scores are automatically calculated between test data and reference data from a flow cytometer.Type: ApplicationFiled: January 11, 2013Publication date: August 29, 2013Applicant: Purdue Research FoundationInventor: Purdue Research Foundation
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Publication number: 20130224881Abstract: A polyrotaxane containing an affinity binding group has been designed and prepared. The polyrotaxane of the invention can be used for characterization and determination of the three-dimensional structures of biological molecules, such as proteins.Type: ApplicationFiled: February 22, 2013Publication date: August 29, 2013Applicant: Purdue Research FoundationInventor: Purdue Research Foundation
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Publication number: 20130202571Abstract: This invention relates to LAP-expressing probiotic bacteria and methods of use thereof to prevent and treat a pathogenic bacterial infection.Type: ApplicationFiled: January 31, 2013Publication date: August 8, 2013Applicant: Purdue Research FoundationInventor: Purdue Research Foundation
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Publication number: 20130202012Abstract: A micro-electromechanical system-type (MEMS) sensor arrangement for wirelessly measuring temperatures is disclosed. The MEMS sensor arrangement includes a multimorph sensor, a sensor coil coupled to the multimorph sensor, and a readout coil configured to be magnetically coupled to the sensor coil to i) energize the sensor coil, and ii) provide a readout of the natural frequency of the multimorph sensor, the sensor coil and the readout coil.Type: ApplicationFiled: January 22, 2013Publication date: August 8, 2013Applicant: PURDUE RESEARCH FOUNDATIONInventor: Purdue Research Foundation
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Publication number: 20130195729Abstract: A gas generation apparatus includes a reaction vessel and a fluid reservoir. The reaction vessel has an internal container therein for a reactant material including a solid portion and a liquid portion. The internal container has a perforated upper portion suitable for containing said solid portion of said reactant material, and a solid lower portion suitable for containing said liquid portion of said reactant material. The fluid reservoir is external to the reaction vessel, and has a variable volume fluid chamber. The fluid reservoir is in fluid connection with the reaction vessel.Type: ApplicationFiled: January 14, 2013Publication date: August 1, 2013Applicant: PURDUE RESEARCH FOUNDATIONInventor: Purdue Research Foundation
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Publication number: 20130189156Abstract: A system and method for decontamination of product is described. An object to be treated, which may be a food product or a medical device, is placed in a substantially closed dielectric container with a working gas. The container is placed in an apparatus capable of producing a controlled electrical discharge so as to create reactive ion species within the package. The object to be treated may be exposed either the immediate products of the electrical discharge or the long lasting reactive ion species, or both, so as to treat the object to reduce or eliminate specific contaminants, which may be biological pathogens or the cause of product spoilage, or inorganic contaminants. The reactive ion species may result from an atmospheric non-equilibrium plasma (ANEP) formed by the apparatus and the treatment may be performed without significantly increasing the bulk temperature of the object being treated.Type: ApplicationFiled: March 11, 2013Publication date: July 25, 2013Applicant: Purdue Research FoundationInventor: Purdue Research Foundation
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Publication number: 20130180969Abstract: Methods and apparatuses for processing materials to enhancing the material's surface strength, improving the material's cyclic and thermal stability of microstructures, and extend the material's fatigue performance. Embodiments include laser shock peening at material temperatures that are moderately elevated (from the material's perspective) above room temperature. Alternate embodiments include laser shock peening at very cold (cryogenic) material temperatures. Still further embodiments include laser shock peening while covering the surface of the material being processed with an active agent that interacts with the laser energy and enhances the pressure exerted on the surface.Type: ApplicationFiled: January 18, 2013Publication date: July 18, 2013Applicant: Purdue Research FoundationInventor: Purdue Research Foundation
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Publication number: 20130177570Abstract: Human anti-human folate receptor beta antibodies and antigen-binding fragments thereof are described, as well as methods of using such antibodies and fragments to treat inflammatory disorders or cancers expressing cell surface FR?.Type: ApplicationFiled: March 8, 2013Publication date: July 11, 2013Applicants: Purdue Research Foundation, ServicesInventors: Purdue Research Foundation, The United States of America, as Represented by the Secretary Department of Health and Human Services
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Publication number: 20130166002Abstract: Illustrative embodiments of systems and methods for wireless magnetic tracking are disclosed. In one illustrative embodiment, a wireless magnetic tracking system may include a plurality of transmitting coils each configured to generate a magnetic field when energized, an active transponder configured to simultaneously (i) obtain measurements of the magnetic field when one of the plurality of transmitting coils is energized and (ii) transmit a wireless signal containing data concerning the measurements, and a computing device configured to (i) cause each of the plurality of transmitting coils to be sequentially energized, (ii) receive the data concerning the measurements, and (iii) determine a position and an orientation of the active transponder relative to the plurality of transmitting coils in response to the data concerning the measurements.Type: ApplicationFiled: December 12, 2012Publication date: June 27, 2013Applicant: PURDUE RESEARCH FOUNDATIONInventor: PURDUE RESEARCH FOUNDATION
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Publication number: 20130144151Abstract: A phenotypic profiling method for drug/dose physiological response of living bodies utilizes feature recognition to segment the information in time-frequency tissue-response spectrograms to construct N-dimensional feature vectors. The feature vectors are used to generate a correlation matrix among a large number of different stimuli in the form of drugs, doses and conditions. Multi-dimensional scaling is applied to the correlation matrix to form a two-dimensional map of response relationships that retains rank distances from the higher-dimensionality feature matrix. The two-dimensional phenotypic profile space displays compact regions indicative of particular physiological responses, such as regions of enhanced active transport, membrane undulations and blebbing.Type: ApplicationFiled: February 6, 2013Publication date: June 6, 2013Applicant: PURDUE RESEARCH FOUNDATIONInventor: Purdue Research Foundation
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Publication number: 20130136783Abstract: A bactericidal or antimicrobial polymeric composition includes a hydrophilic first comonomer copolymerized to a second comonomer to produce a polymeric composition that is more hydrophilic or more bactericidal or antimicrobial in an aqueous solution than either of the comonomers alone. Methods for identifying bactericidal or antimicrobial polymers, methods for rendering materials bactericidal or antimicrobial, and methods for using bactericidal or antimicrobial compositions to kill or reduce bacterial or microbial growth are also described. Applications for the inventive compositions include their use in catheters, stents, medical devices, contact lenses; root canal fillers; fibers; paper; and/or wound dressing.Type: ApplicationFiled: January 23, 2013Publication date: May 30, 2013Applicant: PURDUE RESEARCH FOUNDATIONInventor: Purdue Research Foundation