Patents by Inventor Qihong Liu

Qihong Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR INCREASING CRUDE OIL PRODUCTION BY CO2 STORAGE IN AQUIFER AND DUMPFLOODING
    Publication number: 20240117714
    Abstract: A method of increasing crude oil production by CO2 storage in an aquifer and dumpflooding includes the following steps. Wells are drilled in an aquifer in an oil-bearing basin for large-scale CO2 storage. A low-production and low-efficiency well in an oil-bearing stratum away from the CO2 storage injection well is selected as an artesian injection well. Formation water in the aquifer with increasing pressure is controlled and guided into the oil-bearing stratum to realize oil displacement by dumpflooding in the oil-bearing stratum.
    Type: Application
    Filed: December 21, 2023
    Publication date: April 11, 2024
    Inventors: Xianmin ZHANG, Qihong FENG, Chen LIU, Kuankuan WU, Zangyuan WU, Yiming ZHANG, Weina LIU, Jianwei GU
  • SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3, 4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20230406856
    Abstract: Provided are certain BTK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 16, 2021
    Publication date: December 21, 2023
    Inventors: Haohan TAN, Qihong LIU, Yunling WANG, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • COMPOUNDS AS PROTEIN KINASE INHIBITORS
    Publication number: 20230174556
    Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: May 14, 2021
    Publication date: June 8, 2023
    Inventors: Zuwen ZHOU, Rui TAN, Hua XU, Qihong LIU, Huajie ZHANG, Bin LIU, Weipeng ZHANG, Zhifu LI, Yanxin LIU, Shu LIN, Xingdong ZHAO, Weibo WANG
  • COMPOUNDS AS BCL-2 INHIBITORS
    Publication number: 20230159527
    Abstract: Provided are certain Bcl-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: May 7, 2021
    Publication date: May 25, 2023
    Inventors: Weipeng ZHANG, Hongbin LIU, Rui TAN, Zhifu LI, Yue RONG, Qihong LIU, Zhifang CHEN, Ling CHEN, Hua XU, Zuwen ZHOU, Jinhua YU, Haohan TAN, Bin LIU, Yunling WANG, Lijun YANG, Chengxi HE, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • Macrocyclic compounds as TRK kinases inhibitors
    Patent number: 11555042
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: January 17, 2023
    Assignee: Fochon Biosciences, Ltd.
    Inventors: Huajie Zhang, Qihong Liu, Chengxi He, Weipeng Zhang, Rui Tan, Bin Liu, Hong Fu, Haohan Tan, Lijun Yang, Hongbin Liu, Yunling Wang, Yuwei Gao, Zongyao Zou, Yanxin Liu, Shu Lin, Tongshuang Li, Xingdong Zhao, Weibo Wang
  • Substituted 2-azabicyclo[3.1.0]hexanes as TRK kinases inhibitors
    Patent number: 11459332
    Abstract: Provided are certain TRK inhibitors of formula (I): pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: October 4, 2022
    Assignee: Fochon Biosciences, Ltd.
    Inventors: Hongbin Liu, Haohan Tan, Chengxi He, Xianlong Wang, Qihong Liu, Zhifu Li, Zuwen Zhou, Yuwei Gao, Lihua Jiang, Li Linghu, Shu Lin, Xingdong Zhao, Weibo Wang
  • SUBSTITUTED PYRROLO [2, 3-b] PYRIDINE AND PYRAZOLO [3,4-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
    Publication number: 20220235049
    Abstract: Provided are certain BTK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: June 1, 2020
    Publication date: July 28, 2022
    Inventors: Haohan TAN, Qihong LIU, Bin LIU, Zhifu LI, Xianlong WANG, Zuwen ZHOU, Weipeng ZHANG, Yunling WANG, Chenglin ZHOU, Yuwei GAO, Lihua JIANG, Yanxin LIU, Zongyao ZOU, Shu LIN, Kai YU, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE AND [1,2,4]TRIAZOLO[1,5-A]PYRIDINE COMPOUNDS AS RET KINASE INHIBITORS
    Publication number: 20220041588
    Abstract: Provided are certain RET inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: September 26, 2019
    Publication date: February 10, 2022
    Inventors: Chengxi HE, Rui TAN, Zuwen ZHOU, Weipeng ZHANG, Yunling WANG, Qihong LIU, Xingdong ZHAO, Yanxin LIU, Yuwei GAO, Shu LIN, Weibo WANG
  • Sulfoximine, sulfonimidamide, sulfondiimine and diimidosulfonamide compounds as inhibitors of indoleamine 2,3-dioxygenase
    Patent number: 11168078
    Abstract: Provided are certain IDO inhibitors or pharmaceutically acceptable salts thereof which can inhibit enzymatic activity of indoleamine 2,3-dioxygenase (IDO) and may be useful for the treatment of diseases and disorders mediated by IDO. In addition, pharmaceutical compositions thereof and methods of use thereof are also provided.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: November 9, 2021
    Assignees: Shanghai Fochon Pharmaceutical Co., Ltd., Fochon Pharmaceuticals, Ltd.
    Inventors: Zhifang Chen, Rui Tan, Qihong Liu, Lijun Yang, Zhifu Li, Haohan Tan, Hongbin Liu, Xingdong Zhao, Min Lin, Jing Sun, Weibo Wang
  • MACROCYCLIC COMPOUNDS AS TRK KINASES INHIBITORS
    Publication number: 20210139506
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 27, 2019
    Publication date: May 13, 2021
    Applicants: Fochon Pharmaceuticals, Ltd., Shanghai Fochon Pharmaceutical Co., LTD.
    Inventors: Huajie ZHANG, Qihong LIU, Chengxi HE, Weipeng ZHANG, Rui TAN, Bin LIU, Hong FU, Haohan TAN, Lijun YANG, Hongbin LIU, Yunling WANG, Yuwei GAO, Zongyao ZOU, Yanxin LIU, Shu LIN, Tongshuang LI, Xingdong ZHAO, Weibo WANG
  • SULFOXIMINE, SULFONIMIDAMIDE, SULFONDIIMINE AND DIIMIDOSULFONAMIDE COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE
    Publication number: 20210070742
    Abstract: Provided are certain IDO inhibitors or pharmaceutically acceptable salts thereof which can inhibit enzymatic activity of indoleamine 2,3-dioxygenase (IDO) and may be useful for the treatment of diseases and disorders mediated by IDO. In addition, pharmaceutical compositions thereof and methods of use thereof are also provided.
    Type: Application
    Filed: November 28, 2017
    Publication date: March 11, 2021
    Inventors: Zhifang CHEN, Rui TAN, Qihong LIU, Lijun YANG, Zhifu LI, Haohan TAN, Hongbin LIU, Xingdong ZHAO, Min LIN, Jing SUN, Weibo WANG
  • SUBSTITUTED (2-AZABICYCLO[3.1.0]HEXAN-2-YL)PYRAZOLO[1,5-a]PYRIMIDINE AND IMIDAZO[1,2-b]PYRIDAZINE COMPOUNDS AS TRK KINASES INHIBITORS
    Publication number: 20210024528
    Abstract: Provided are certain TRK inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: March 13, 2019
    Publication date: January 28, 2021
    Inventors: Hongbin LIU, Haohan TAN, Chengxi HE, Xianlong WANG, Qihong LIU, Zhifu LI, Zuwen ZHOU, Yuwei GAO, Lihua JIANG, Li LINGHU, Shu LIN, Xingdong ZHAO, Weibo WANG
  • Indolizine derivatives, composition and methods of use
    Patent number: 10894038
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Grant
    Filed: December 26, 2016
    Date of Patent: January 19, 2021
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO. LTD., FOCHON PHARMACEUTICALS, LTD.
    Inventors: Tongshuang Li, Xingdong Zhao, Chuiliang Yu, Haohan Tan, Xianlong Wang, Rui Tan, Bin Liu, Weipeng Zhang, Huajie Zhang, Qihong Liu, Zuwen Zhou, Zhifu Li, Yue Rong, Jing Sun, Weibo Wang
  • INDOLIZINE DERIVATIVES, COMPOSITION AND METHODS OF USE
    Publication number: 20200113876
    Abstract: Provided are certain URAT1 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Application
    Filed: December 26, 2016
    Publication date: April 16, 2020
    Inventors: Tonshuang LI, Xingdong ZHAO, Chuiliang YU, Haohan TAN, Xianlong WANG, Rui TAN, BIN LIU, Weipeng ZHANG, Huajie ZHANG, Qihong LIU, Zuwen ZHOU, Zhifu LI, Yue RONG, Jing SUN, Weibo WANG
  • Certain protein kinase inhibitor
    Patent number: 10450316
    Abstract: Provided are certain CDK4/6 inhibitors with the structure of formula (I), pharmaceutical compositions thereof, and methods of use therefor. The compounds are of the class of pyrimidin-2 amine derivatives, useful for the treatment of hyper-proliferative diseases.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: October 22, 2019
    Assignees: CHONGQING FOCHON PHARMACEUTICAL CO., LTD., SHANGHAI FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Xingdong Zhao, Tongshuang Li, Haohan Tan, Zhifang Chen, Ling Chen, Qihong Liu, Yue Rong, Lijun Yang, Xianlong Wang, Rui Tan, Zuwen Zhou, Bin Liu, Min Lin, Lihua Jiang, Yanxin Liu, Li Linghu, Jing Sun, Weibo Wang
  • Certain protein kinase inhibitors
    Patent number: 10328060
    Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Grant
    Filed: November 1, 2015
    Date of Patent: June 25, 2019
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO., LTD., SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES, CHONGQING FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Xingdong Zhao, Jian Ding, Linghua Meng, Meiyu Geng, Tongshuang Li, Zuwen Zhou, Ling Chen, Qihong Liu, Xianlong Wang, Lijun Yang, Yue Rong, Rui Tan, Chuiliang Yu, Lihua Jiang, Yanxin Liu, Li Linghu, Jing Sun, Weibo Wang
  • CERTAIN PROTEIN KINASE INHIBITOR
    Publication number: 20180291027
    Abstract: Provided are certain CDK4/6 inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Application
    Filed: April 28, 2016
    Publication date: October 11, 2018
    Inventors: Xingdong ZHAO, Tongshuang LI, Haohan TAN, Zhifang CHEN, Ling CHEN, Qihong LIU, Yue RONG, Lijun YANG, Xianlong WANG, Rui TAN, Zuwen ZHOU, Bin LIU, Min LIN, Lihua JIANG, Yanxin LIU, Li LINGHU, Jing SUN, Weibo WANG
  • Certain protein kinase inhibitors
    Patent number: 10087195
    Abstract: Provided are compound of formula (I) as certain CDK4/6 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: October 2, 2018
    Assignees: SHANGHAI FOCHON PHARMACEUTICAL CO., LTD., CHONGQING FOCHON PHARMACEUTICAL CO., LTD.
    Inventors: Weibo Wang, Xingdong Zhao, Tongshuang Li, Qiang Tian, Huajie Zhang, Haohan Tan, Xianlong Wang, Qihong Liu, Zhifu Li, Weipeng Zhang, Zhifang Chen, Lihua Jiang, Yanxin Liu, Li Linghu, Min Lin, Jing Sun
  • Certain protein kinase inhibitors
    Patent number: 10022374
    Abstract: Disclosed herein are protein kinase inhibitors, more particularly pyridazine derivatives and pharmaceutical compositions thereof, and method of use thereof.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: July 17, 2018
    Assignee: Shanghai Fochon Pharmaceutical Co., Ltd.
    Inventors: Weibo Wang, Xingdong Zhao, Quan Yuan, Hailong Shi, Qiang Tian, Qihong Liu, Zuwen Zhou, Xianlong Wang, Zhifang Chen, Ling Chen, Haohan Tan, Bo Fang, Lihua Jiang, Yanxin Liu, Jing Sun, Fanxin Zeng, Tongshuang Li
  • CERTAIN PROTEIN KINASE INHIBITORS
    Publication number: 20180036293
    Abstract: Provided are certain PI3K inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
    Type: Application
    Filed: November 1, 2015
    Publication date: February 8, 2018
    Applicants: Shanghai Fochon Pharmaceutical Co., Ltd., Shanghai Institute of Materia Medica Chinese Academy of Sciences, ChongQing Fochon Pharmaceutical Co., Ltd.
    Inventors: Xingdong ZHAO, Jian DING, Linghua MENG, Meiyu GENG, Tongshuang LI, Zuwen ZHOU, Ling CHEN, Qihong LIU, Xianlong WANG, Lijun YANG, Yue RONG, Rui TAN, Chuiliang YU, Lihua JIANG, Yanxin LIU, Li LINGHU, Jing SUN, Weibo WANG