Patents by Inventor Qun Gu

Qun Gu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9667219
    Abstract: Methods and apparatuses for measuring a phase noise level in an input signal are disclosed. An input signal can be delayed to generate a delayed version of the input signal. Next, a phase difference can be detected between the input signal and the delayed version of the input signal. A phase noise level in the input signal can then be determined based on the detected phase difference. The measured phase noise level can then be used to suppress phase noise in the input signal.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: May 30, 2017
    Assignee: The Regents of the University of California
    Inventor: Qun Gu
  • Patent number: 9621152
    Abstract: A switch comprising a plurality of inductors and a plurality of shunt transistors is described. Each inductor can be electrically coupled between adjacent shunt transistors to form a distributed switch structure. At least two inductors in the plurality of inductors can be inductively coupled with each other. The plurality of inductors can correspond to portions of a coupling inductor, wherein the coupling inductor can have an irregular octagonal shape.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: April 11, 2017
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Ran Shu, Adrian J. Tang, Qun Gu, Brian J. Drouin
  • Patent number: 9574228
    Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: February 21, 2017
    Assignee: The Curators of the University of Missouri
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Publication number: 20170002403
    Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
    Type: Application
    Filed: July 13, 2016
    Publication date: January 5, 2017
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Publication number: 20160351489
    Abstract: An interconnect is described that comprises an interconnect channel, and two channel couplers coupled to the two ends of the interconnect channel through respective stoppers that provide a gap between the channel couplers and the interconnect channel. Each channel coupler can comprise a coplanar waveguide, a microstrip line, and a patch-antenna based coupler. The interconnect can enable communication between integrated circuits using signal waves having a frequency between 100 GHz and 3 THz.
    Type: Application
    Filed: May 27, 2016
    Publication date: December 1, 2016
    Applicant: The Regents of the University of California
    Inventors: Qun Gu, Xiaoguang Liu, Neville C. Luhmann, JR., Bo Yu
  • Publication number: 20160336934
    Abstract: A switch comprising a plurality of inductors and a plurality of shunt transistors is described. Each inductor can be electrically coupled between adjacent shunt transistors to form a distributed switch structure. At least two inductors in the plurality of inductors can be inductively coupled with each other. The plurality of inductors can correspond to portions of a coupling inductor, wherein the coupling inductor can have an irregular octagonal shape.
    Type: Application
    Filed: May 13, 2016
    Publication date: November 17, 2016
    Inventors: Ran Shu, Adrian J. Tang, Qun Gu, Brian J. Drouin
  • Publication number: 20160319333
    Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
    Type: Application
    Filed: June 15, 2016
    Publication date: November 3, 2016
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Publication number: 20160315601
    Abstract: Methods and apparatuses for measuring a phase noise level in an input signal are disclosed. An input signal can be delayed to generate a delayed version of the input signal. Next, a phase difference can be detected between the input signal and the delayed version of the input signal. A phase noise level in the input signal can then be determined based on the detected phase difference. The measured phase noise level can then be used to suppress phase noise in the input signal.
    Type: Application
    Filed: April 22, 2016
    Publication date: October 27, 2016
    Applicant: The Regents of the University of California
    Inventor: Qun Gu
  • Patent number: 9395353
    Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: July 19, 2016
    Assignee: The Curators of the University of Missouri
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Publication number: 20160177381
    Abstract: A versatile detection method is disclosed that utilizes a base-pair-specific inter-strand lock for genetic and epigenetic detection. Reagents, devices, etc., for implementing the method have also been discovered and/or developed. In certain embodiments, compounds have been identified to be able to specifically bind certain mismatched base pairs including T-T, U-T, and C-C base pair mismatches using either Hg2+ or Ag+. Such binding can strengthen the base-pair hybridization in orders of magnitude, forming a so-called reversible inter-strand lock that can greatly stabilize double-stranded nucleic acid fragments.
    Type: Application
    Filed: August 5, 2014
    Publication date: June 23, 2016
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Patent number: 9365672
    Abstract: A polylactic acid triblock copolymer and a preparation method thereof are described. The polylactic acid triblock copolymer comprises an aromatic polyester oligomer block and a polylactic acid block. The polylactic acid triblock copolymer is obtained by reacting an aromatic polyester oligomer with a monomer lactide at a desired temperature. The polylactic acid block copolymer has a regular structure indicated by peak melting temperatures (Tm) corresponding to the aromatic polyester oligomer block and the polylactic acid block, respectively. Examples of the aromatic polyester oligomer block include polyethylene terephthalate, polybutylene terephthalate, and polyethylene 1,4-naphthalate. Examples of the monomer lactide include L-lactide and D-lactide.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: June 14, 2016
    Assignee: Ningbo Institute of Material Technology and Engineering, Chinese Academy of Sciences
    Inventors: Jian Zhou, Peng Chen, Qun Gu, Jun Li, Wentao Shi, Zongbao Wang, Zhiqiang Jiang, Xuedong Wu
  • Publication number: 20140309129
    Abstract: The present invention provides a new and improved multiplexed oligonucleotide detection method based on the nanopore technology with one or more probes containing a sequence with complementarity to the target oligonucleotide, a terminal extension at the probe's 3? terminus, 5? terminus, or both termini and a label attached to the terminus. The improved probes and probe sets enable sensitive, selective, and direct multiplex detection, differentiation and quantification of distinct target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method based on miRNA levels in the patient's tissue sample.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 16, 2014
    Applicant: The Curators of the University of Missouri
    Inventors: Li-Qun Gu, Xinyue Zhang
  • Publication number: 20130324680
    Abstract: Disclosed are a polylactic acid block copolymer and a preparation method thereof. The polylactic acid block copolymer comprises block A and block B, and is presented as B-b-A-b-B triblock structure, wherein the block A is a cyclic aromatic polyester oligomer block, and the block B is a polylactic acid block. The polylactic acid block copolymer is obtained by ring-opening copolymerization of a cyclic aromatic polyester oligomer and a lactide. Disclosed are another polylactic acid block copolymer and a preparation method thereof. The polylactic acid block copolymer comprises block A and block B, and is presented as B-b-A-b-B triblock structure, wherein the block A is an aromatic polyester block with two hydroxyl end groups, and the block B is a polylactic acid block. The polylactic acid block copolymer is obtained by ring-opening copolymerization of an aromatic polyester with two hydroxyl end groups and a lactide.
    Type: Application
    Filed: November 29, 2011
    Publication date: December 5, 2013
    Applicant: NINGBO INSTITUTE OF MATERIAL TECHNOLOGY AND ENGINEERING, CHINESE ACADEMY OF SCIENCES
    Inventors: Jian Zhou, Peng Chen, Qun Gu, Jun Li, Wentao Shi, Zongbao Wang, Zhiqiang Jiang, Xuedong Wu
  • Publication number: 20130220809
    Abstract: The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3? terminus, 5? terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample.
    Type: Application
    Filed: July 14, 2011
    Publication date: August 29, 2013
    Inventors: Li-Qun Gu, Yong Wang, Kai Tian
  • Patent number: 8446362
    Abstract: A mouse is disclosed that comprises a main body, at least one function key, a position sensor and a data transmission line. The main body has a hand-shaped groove, a first surface disposed at a bottom of the hand-shaped groove, and a reverse surface to the first surface. The at least one function key is disposed on the first surface for producing at least one function signal. The position sensor is disposed on the reverse surface for sensing movement of the main body to produce a position signal. And the data transmission line is coupled to the main body for transmitting the function signal and the position signal to an electronic system or apparatus for operating the electronic system or apparatus.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: May 21, 2013
    Assignees: Inventec Appliances (Shanghai) Co. Ltd., Inventec Appliances Corp.
    Inventor: Qun Gu
  • Patent number: 8131250
    Abstract: A Self-Synchronized Radio Frequency RF-Interconnect (SSRFI), based on capacitor coupling and peak detection, for vertically interconnecting active device layers in three-dimensional (3D) integrated circuits (IC), as well as wireless communication and RF signal transmission/receiving.
    Type: Grant
    Filed: February 17, 2006
    Date of Patent: March 6, 2012
    Assignee: The Regents of the University of California
    Inventors: Qun Gu, Zhiwei Xu, Jenwei Ko, Mau Chung Frank Chang
  • Publication number: 20110210919
    Abstract: A mouse is disclosed that comprises a main body, at least one function key, a position sensor and a data transmission line. The main body has a hand-shaped groove, a first surface disposed at a bottom of the hand-shaped groove, and a reverse surface to the first surface. The at least one function key is disposed on the first surface for producing at least one function signal. The position sensor is disposed on the reverse surface for sensing movement of the main body to produce a position signal. And the data transmission line is coupled to the main body for transmitting the function signal and the position signal to an electronic system or apparatus for operating the electronic system or apparatus.
    Type: Application
    Filed: February 18, 2011
    Publication date: September 1, 2011
    Applicants: INVENTEC APPLIANCES (SHANGHAI) CO. LTD., INVENTEC APPLIANCES CORP.
    Inventor: QUN GU
  • Patent number: 7867716
    Abstract: The present invention includes an apparatus, system and method for stochastic sensing of an analyte to a protein pore. The protein pore may be an engineer protein pore, such as an ion channel at temperatures above 55° C. and even as high as near 100° C. The analyte may be any reactive analyte, including chemical weapons, environmental toxins and pharmaceuticals. The analyte covalently bonds to the sensor element to produce a detectable electrical current signal. Possible signals include change in electrical current. Detection of the signal allows identification of the analyte and determination of its concentration in a sample solution. Multiple analytes present in the same solution may also be detected.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: January 11, 2011
    Assignee: The Texas A&M University System
    Inventors: Xiaofeng Kang, Li Qun Gu, Stephen Cheley, Hagan Bayley
  • Patent number: D735044
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: July 28, 2015
    Assignee: MARS, INCORPORATED
    Inventor: Qun Gu
  • Patent number: D761115
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: July 12, 2016
    Assignee: MARS, INCORPORATED
    Inventor: Qun Gu