Patents by Inventor R. Rox Anderson
R. Rox Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090024193Abstract: The present invention provides method and apparatus for treating tissue in a region at depth by applying optical radiation thereto of a wavelength able to reach the depth of the region and of a selected relatively low power for a duration sufficient for the radiation to effect the desired treatment while concurrently cooling tissue above the selected region to protect such tissue. Treatment may be enhanced by applying mechanical, acoustic or electrical stimulation to the region.Type: ApplicationFiled: February 15, 2008Publication date: January 22, 2009Applicants: PALOMAR MEDICAL TECHNOLOGIES, INC., THE GENERAL HOSPITAL CORPORATION d/b/a MASSACHUSETTS GENERAL HOSPITALInventors: Gregory B. Altshuler, Andrei V. Erofeev, Henry H. Zenzie, R. Rox Anderson, Dierer Manstein, James Burke, III, Andrew Radl, Michael Z. Smirnov
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Publication number: 20080269733Abstract: A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.Type: ApplicationFiled: July 3, 2008Publication date: October 30, 2008Inventors: R. Rox Anderson, Edward Victor Ross, James C. Hsia, Kathleen McMillan
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Patent number: 7351252Abstract: The present invention provides method and apparatus for treating tissue in a region at depth by applying optical radiation thereto of a wavelength able to reach the depth of the region and of a selected relatively low power for a duration sufficient for the radiation to effect the desired treatment while concurrently cooling tissue above the selected region to protect such tissue. Treatment may be enhanced by applying mechanical, acoustic or electrical stimulation to the region.Type: GrantFiled: June 19, 2003Date of Patent: April 1, 2008Assignee: Palomar Medical Technologies, Inc.Inventors: Gregory B. Altshuler, Andrei V. Erofeev, Henry H. Zenzie, R. Rox Anderson, Dieter Manstein, James Burke, III, Andrew Radl, Michael Z. Smirnov
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Patent number: 7331953Abstract: The present invention provides improved methods and apparatus for skin treatment. The apparatus includes multiple sources of optical energy or several blades that are scanned along a region of skin to form micro-line patterns of damaged tissue. The micro-lines are small in at least one dimension, having a width of less than about 1 mm, and the wounded regions promote beneficial results by stimulation of wound healing and tissue remodeling.Type: GrantFiled: April 1, 2005Date of Patent: February 19, 2008Assignee: The Gneral Hospital CorporationInventors: Dieter Manstein, R. Rox Anderson
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Patent number: 7217266Abstract: A platform Smart Scalpel system using rapid real-time feedback for effecting laser treatment. The platform system includes an imaging system for rapid real-time detection of tissue characteristics, a processing system for processing the detected characteristics, and a treatment system for effecting treatment in accordance with results of the processing. The platform system provides for preprogramming and real-time inputting conditions and parameters for diagnosis using the imaging system and/or treatment using the treatment system.Type: GrantFiled: May 30, 2001Date of Patent: May 15, 2007Inventors: R. Rox Anderson, Ian W. Hunter, Colin J. H. Brenan, Keng Hui Lim, Elizabeth Sebern
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Patent number: 7077840Abstract: Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, various beam focusing techniques to reduce scattering and/or other techniques for reducing the cost and/or increasing the efficacy of optical radiation for use in hair removal and other dermatological treatments. A number of embodiments are included for achieving the various objectives indicated above.Type: GrantFiled: October 21, 2002Date of Patent: July 18, 2006Assignees: Palomar Medical Technologies, Inc., The General Hospital CorporationInventors: Gregory B. Altshuler, R. Rox Anderson
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Patent number: 7060061Abstract: A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method/apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm and 1230 nm, 1690 nm to 1780 nm, or 2250 nm to 2450 nm with a fluence and duration sufficient to achieve a desired treatment. For preferred embodiments, the irradiation wavelength is between 900–930 nm, 1190–1220 nm, 1700–1730 nm, or 2280–2350 nm. The method and apparatus may for example be used to target one or more sebaceous glands for the treatment of acne or hair removal, to target subcutaneous fat for removal thereof or for targeting fat on anatomical elements for various purposes.Type: GrantFiled: August 12, 2003Date of Patent: June 13, 2006Assignees: Palomar Medical Technologies, Inc., The General Hospital CorporationInventors: Gregory B. Altshuler, R. Rox Anderson, Dieter Manstein
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Patent number: 7044959Abstract: A method and apparatus are provided for hair growth management by applying low energy optical radiation to a treatment area of a patient's skin, which radiation is sufficient to at least traumatize a matrix portion of each follicle being treated, but not to cause either necrosis of most of each said follicle or immediate gross alteration of any hair shaft therein. The treatments are preferably performed a plurality of times at selected time intervals to achieve a desired level of hair growth management.Type: GrantFiled: March 12, 2003Date of Patent: May 16, 2006Assignees: Palomar Medical Technologies, Inc., The General Hospital CorporationInventors: R. Rox Anderson, Gregory B. Altshuler, Dieter Manstein, Ilya Yaroslavsky, Michael Smotrich
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Patent number: 6997923Abstract: A method and apparatus are provided for performing a therapeutic treatment on a patient's skin by concentrating applied radiation of at least one selected wavelength at a plurality of selected, three-dimensionally located, treatment portions, which treatment portions are within non-treatment portions. The ratio of treatment portions to the total volume may vary from 0.1% to 90%, but is preferably less than 50%. Various techniques, including wavelength, may be utilized to control the depth to which radiation is concentrated and suitable optical systems may be provided to concentrate applied radiation in parallel or in series for selected combinations of one or more treatment portions.Type: GrantFiled: December 27, 2001Date of Patent: February 14, 2006Assignees: Palomar Medical Technologies, Inc., The General Hospital CorporationInventors: R. Rox Anderson, Gregory B. Altshuler, Dieter Manstein, Sergey B. Biruchinsky, Andrei V. Erofeev
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Publication number: 20040249274Abstract: The present invention is directed to a novel multi-spectral contrast agent-enhanced polarized light imaging technique that enables rapid imaging of large tissue fields. The imaging device includes a tunable monochromatic light source and a CCD camera. Linear polarizers are placed into both the incident and collected light pathways in order to limit the measurement volume to the superficial tissue layers. To enhance the tumor contrast in the image, aqueous solutions of toluidine blue or methylene blue are topically applied.Type: ApplicationFiled: March 18, 2004Publication date: December 9, 2004Inventors: Anna N. Yaroslavsky, R. Rox Anderson
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Publication number: 20040204700Abstract: The present invention relates to microscission methods and devices used for the manipulation or modification of the body tissue by the formation of microconduits in a tissue. The term “microconduit” refers to a small opening, channel, or hole into, or through, a tissue, that allows transfer of materials by liquid flow, and by electrophoresis, the microconduit being formed upon impact of a plurality of accelerated microparticles with the surface of the tissue. This process of “microscission” comprises forming at least one microconduit in tissue including the steps of: accelerating a plurality of microparticles to a velocity that causes the microparticles to penetrate a region of tissue surface upon impingement of the microparticles on the tissue surface; and directing the microparticle towards the region of tissue surface, thereby causing the microparticles to penetrate the tissue and form a microconduit in the tissue.Type: ApplicationFiled: March 15, 2004Publication date: October 14, 2004Inventors: James C. Weaver, R. Rox Anderson, Terry O. Herndon
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Publication number: 20040143247Abstract: A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.Type: ApplicationFiled: October 31, 2003Publication date: July 22, 2004Inventors: R. Rox Anderson, Edward Victor Ross, James C. Hsia, Kathleen McMillan
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Publication number: 20040093042Abstract: The present invention provides method and apparatus for treating tissue in a region at depth by applying optical radiation thereto of a wavelength able to reach the depth of the region and of a selected relatively low power for a duration sufficient for the radiation to effect the desired treatment while concurrently cooling tissue above the selected region to protect such tissue. Treatment may be enhanced by applying mechanical, acoustic or electrical stimulation to the region.Type: ApplicationFiled: June 19, 2003Publication date: May 13, 2004Applicants: Palomar Medical Technologies, Inc., THE GENERAL HOSPITAL CORPORATIONInventors: Gregory B. Altshuler, Andrei V. Erofeev, Henry H. Zenzie, R. Rox Anderson, Dieter Manstein, James Burke, Andrew Radl, Michael Z. Smirnov
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Patent number: 6706032Abstract: The present invention relates to methods and devices used for the formation of microconduits in a tissue. The term “microconduit” refers to a small opening, channel, or hole into, or through, a tissue, that allows transfer of materials by liquid flow, and by electrophoresis, the microconduit being formed upon impact of a plurality of accelerated microparticles with the surface of the tissue. A method is described for forming at least one microconduit in tissue including the steps of: accelerating a plurality of microparticles to a velocity that causes the microparticles to penetrate a region of tissue surface upon impingement of the microparticles on the tissue surface; and directing the microparticle towards the region of tissue surface, thereby causing the microparticles to penetrate the tissue and form a microconduit in the tissue. According to an embodiment, microparticles are accelerated by being hit with a moving, solid surface.Type: GrantFiled: June 7, 2001Date of Patent: March 16, 2004Assignees: Massachusetts Institute of Technology, The General Hospital CorporationInventors: James C. Weaver, R. Rox Anderson, Terry O Herndon, T. R. Gowrishankar, Elizabeth A. Gift, Salvador Gonzalez
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Publication number: 20040034319Abstract: A method and apparatus are provided for hair growth management by applying low energy optical radiation to a treatment area of a patient's skin, which radiation is sufficient to at least traumatize a matrix portion of each follicle being treated, but not to cause either necrosis of most of each said follicle or immediate gross alteration of any hair shaft therein. The treatments are preferably performed a plurality of times at selected time intervals to achieve a desired level of hair growth management.Type: ApplicationFiled: March 12, 2003Publication date: February 19, 2004Applicant: Palomar Medical Technologies, Inc.Inventors: R. Rox Anderson, Gregory B. Altshuler, Dieter Manstein, Ilya Yaroslavsky, Michael Smotrich
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Publication number: 20040034341Abstract: A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method/apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm and 1230 nm, 1690 nm to 1780 nm, or 2250 nm to 2450 nm with a fluence and duration sufficient to achieve a desired treatment. For preferred embodiments, the irradiation wavelength is between 900-930 nm, 1190-1220 nm, 1700-1730 nm, or 2280-2350 nm. The method and apparatus may for example be used to target one or more sebaceous glands for the treatment of acne or hair removal, to target subcutaneous fat for removal thereof or for targeting fat on anatomical elements for various purposes.Type: ApplicationFiled: August 12, 2003Publication date: February 19, 2004Applicants: Palomar Medical Technologies, Inc., The General Hospital CorporationInventors: Gregory B. Altshuler, R. Rox Anderson, Dieter Manstein
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Patent number: 6659999Abstract: A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.Type: GrantFiled: June 5, 2000Date of Patent: December 9, 2003Assignee: Candela CorporationInventors: R. Rox Anderson, Edward Victor Ross, Jr., James C. Hsia, Kathleen McMillan
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Publication number: 20030199859Abstract: A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method/apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm and 1230 nm, 1690 nm to 1780 nm, or 2250 nm to 2450 nm with a fluence and duration sufficient to achieve a desired treatment. For preferred embodiments, the irradiation wavelength is between 900-930 nm, 1190-1220 nm, 1700-1730 nm, or 2280-2350 nm. The method and apparatus may for example be used to target one or more sebaceous glands for the treatment of acne or hair removal, to target subcutaneous fat for removal thereof or for targeting fat on anatomical elements for various purposes.Type: ApplicationFiled: May 21, 2003Publication date: October 23, 2003Inventors: Gregory B. Altshuler, R. Rox Anderson, Dieter Manstein
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Patent number: 6605080Abstract: A method and apparatus are provided for targeting lipid-rich tissue to effect a desired, the method/apparatus involving irradiating the lipid-rich tissue with energy at a wavelength preferentially absorbed by lipid cells, such wavelength being preferably in a band between 880 nm and 935 nm, 1150 nm and 1230 nm, 1690 nm to 1780 nm, or 2250 nm to 2450 nm with a fluence and duration sufficient to achieve a desired treatment. For preferred embodiments, the irradiation wavelength is between 900-930 nm, 1190-1220 nm, 1700-1730 nm, or 2280-2350 nm. The method and apparatus may for example be used to target one or more sebaceous glands for the treatment of acne or hair removal, to target subcutaneous fat for removal thereof or for targeting fat on anatomical elements for various purposes.Type: GrantFiled: March 26, 1999Date of Patent: August 12, 2003Assignees: The General Hospital Corporation, Palomar Medical Technologies, Inc.Inventors: Gregory B. Altshuler, R. Rox Anderson, Dieter Manstein
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Publication number: 20030055414Abstract: Methods and apparatus for dermatology treatment are provided which involve the use of continuous wave (CW) radiation, preheating of the treatment volume, precooling, cooling during treatment and post-treatment cooling of the epidermis above the treatment volume, various beam focusing techniques to reduce scattering and/or other techniques for reducing the cost and/or increasing the efficacy of optical radiation for use in hair removal and other dermatological treatments. A number of embodiments are included for achieving the various objectives indicated above.Type: ApplicationFiled: October 21, 2002Publication date: March 20, 2003Inventors: Gregory B. Altshuler, R. Rox Anderson