Patents by Inventor Rachael A. Powers

Rachael A. Powers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Non-covalent inhibitors of AmpC ?-lactamase
    Patent number: 7541381
    Abstract: ?-lactamases are the most widespread resistance mechanism to ?-lactam antibiotics, such as penicillins and cephalosporins. In response to these enzymes, inhibitors have been introduced. Unfortunately, these inhibitors are also ?-lactams, and resistance to them has developed rapidly. Consequently, the present invention provides a novel structure-based approach to inhibitors of these enzymes.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: June 2, 2009
    Assignee: Northwestern University
    Inventors: Brian K. Shoichet, Rachael A. Powers