Patents by Inventor Rachel Ben-Levy

Rachel Ben-Levy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES AND USES THEREOF
    Publication number: 20090220486
    Abstract: The present invention provides antibodies or fragments thereof that bind to cancer cells and is important in physiological phenomena, such as cell rolling and metastasis. Therapeutic and diagnostic methods and compositions using such antibody fragments thereof are also provided. The methods and compositions according to the present invention can be used in targeting therapeutic agents and in diagnosis, prognosis, and staging of and therapy for such diseases as cancer, including tumor growth and metastasis, leukemia, auto-immune disease, and inflammatory disease. Also provided is a library of immunoglobulin binding domains having a diverse antigen-binding domain for complementary binding, wherein the library has diversity only in heavy chain CDR3.
    Type: Application
    Filed: January 8, 2008
    Publication date: September 3, 2009
    Inventors: Daniel Plaksin, Avigdor Levanon, Esther Szanton, Yocheved Hagay, Rachel Ben-Levy, Yael Nisgav, Yariv Kanfi
  • ANTIBODIES AND USES THEREOF
    Publication number: 20080274100
    Abstract: The present invention provides antibodies or fragments thereof that bind to co-receptor CCR5 or CXCR4.
    Type: Application
    Filed: January 3, 2008
    Publication date: November 6, 2008
    Inventors: Rachel Ben-Levy, Yael Nisgav, Yariv Kanfi
  • Antibodies and uses thereof
    Publication number: 20050266009
    Abstract: The present invention provides antibodies or fragments thereof that bind to co-receptor CCR5 or CXCR4.
    Type: Application
    Filed: June 27, 2005
    Publication date: December 1, 2005
    Inventors: Daniel Plaksin, Avigdor Levanon, Esther Szanton, Yocheved Hagay, Rachel Ben-Levy, Yael Nisgav, Yariv Kanfi
  • Specific human antibodies
    Publication number: 20050152906
    Abstract: The present invention provides antibodies that bind an epitope of PSGL-1 comprising the motif D-X-Y-D, wherein X represents any amino acid or the covalent linkage between D and Y, and Y is sulfated, which antibody can be complexed with one or more copies of an agent. The antibodies of the invention can be used in a method of inducing antibody-dependent cell cytotoxicity and/or stimulating natural killer (NK) cells or T cells. In addition, by administering these antibodies to a patient in need thereof, a method of inducing cell death is provided. A method of preventing infection by a virus (e.g., HIV) by administering to a patient in need thereof an antibody of the present invention is also provided. The, present invention also provides a method of introducing an agent into a cell that expresses sulfated PSGL-1 by coupling or complexing an agent to an antibody of the present invention and administering the complex to the cell.
    Type: Application
    Filed: June 30, 2004
    Publication date: July 14, 2005
    Inventors: Avigdor Levanon, Tikva Vogel, Daniel Plaksin, Tuvia Peretz, Boaz Amit, Lena Cooperman, Yocheved Hagay, Esther Szanton, Yariv Kanfi, Rachel Ben-Levy, Tali Szrajber
  • Antibodies and uses thereof
    Publication number: 20050069955
    Abstract: The present invention provides antibodies or fragments thereof that bind to cancer cells and is important in physiological phenomena, such as cell rolling and metastasis. Therapeutic and diagnostic methods and compositions using such antibody fragments thereof are also provided. The methods and compositions according to the present invention can be used in targeting therapeutic agents and in diagnosis, prognosis, and staging of and therapy for such diseases as cancer, including tumor growth and metastasis, leukemia, auto-immune disease, and inflammatory disease. Also provided is a library of immunoglobulin binding domains having a diverse antigen-binding domain for complementary binding, wherein the library has diversity only in heavy chain CDR3.
    Type: Application
    Filed: June 30, 2004
    Publication date: March 31, 2005
    Inventors: Daniel Plaksin, Avigdor Levanon, Esther Szanton, Yocheved Hagay, Rachel Ben-Levy, Yael Nisgav, Yariv Kanfi
  • Antibodies and uses thereof
    Publication number: 20040208877
    Abstract: The present invention provides antibodies or fragments thereof that bind to cancer cells and are important in physiological phenomena, such as cell rolling and metastasis. Therapeutic and diagnostic, prognostic or staging methods and compositions using such antibodies or fragments thereof are also provided. The methods and compositions according to the present invention can be used in diagnosis of and therapy for such diseases as cancer, including tumor growth and metastasis, leukemia, auto-immune disease, and inflammatory disease.
    Type: Application
    Filed: June 30, 2003
    Publication date: October 21, 2004
    Inventors: Avigdor Levanon, Rachel Ben-Levy, Daniel Plaksin, Esther Szanton, Yocheved Hagai, Hagit Hoch Mar-Chaim