Patents by Inventor Radislav Potyrailo

Radislav Potyrailo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190043333
    Abstract: Methods, systems, and apparatus to monitor component status in a bioprocessing environment are disclosed and described. Certain examples provide a sensor device for a disposable bioprocessing component. The example sensor device includes a first portion affixed to the component, the first portion configured to provide an identifier associated with the component. The example sensor device also includes a second portion configured to provide a status indication based on a state of the component. The example sensor device is configured to transmit the identifier and status indication to a control computer associated with a bioprocessing platform including the component.
    Type: Application
    Filed: October 1, 2018
    Publication date: February 7, 2019
    Applicant: GE Healthcare Bio-Sciences AB
    Inventors: Radislav A. Potyrailo, Klaus Gebauer, Kajsa Stridsberg-Friden, Timothy A. Wortley
  • Patent number: 10089850
    Abstract: Methods, systems, and apparatus to monitor component status in a bioprocessing environment are disclosed and described. Certain examples provide a sensor device for a disposable bioprocessing component. The example sensor device includes a first portion affixed to the component, the first portion configured to provide an identifier associated with the component. The example sensor device also includes a second portion configured to provide a status indication based on a state of the component. The example sensor device is configured to transmit the identifier and status indication to a control computer associated with a bioprocessing platform including the component.
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: October 2, 2018
    Assignee: GE Healthcare Bio-Sciences AB
    Inventors: Radislav A. Potyrailo, Klaus Gebauer, Kajsa Stridsberg-Friden, Timothy A. Wortley
  • Patent number: 9946902
    Abstract: This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory chip (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written in sequence into the memory chip, so that the redundant information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: April 17, 2018
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Manuel Nyffeler, Radislav A. Potyrailo, Vincent F. Pizzi, William G. Morris, Gerard J. Gach, Vijay Singh
  • Patent number: 9658178
    Abstract: A sensor includes a resonant transducer, the resonant transducer being configured to determine the composition of an emulsion. The composition of the emulsion is determined by measuring the complex impedance spectrum values of the mixture of the emulsion and applying multivariate data analysis to the values.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: May 23, 2017
    Assignee: General Electric Company
    Inventors: Cheryl Margaret Surman, William Chester Platt, William Guy Morris, Steven Go, Jon Albert Dieringer, Radislav A. Potyrailo
  • Publication number: 20170124845
    Abstract: Methods, systems, and apparatus to monitor component status in a bioprocessing environment are disclosed and described. Certain examples provide a sensor device for a disposable bioprocessing component. The example sensor device includes a first portion affixed to the component, the first portion configured to provide an identifier associated with the component. The example sensor device also includes a second portion configured to provide a status indication based on a state of the component. The example sensor device is configured to transmit the identifier and status indication to a control computer associated with a bioprocessing platform including the component.
    Type: Application
    Filed: January 16, 2017
    Publication date: May 4, 2017
    Applicant: GE Healthcare Bio-Sciences AB
    Inventors: Radislav A. Potyrailo, Klaus Gebauer, Kajsa Stridsberg-Friden, Timothy A. Wortley
  • Patent number: 9571904
    Abstract: Methods, systems, and apparatus to monitor component status in a bioprocessing environment are disclosed and described. Certain examples provide a sensor device for a disposable bioprocessing component. The example sensor device includes a first portion affixed to the component, the first portion configured to provide an identifier associated with the component. The example sensor device also includes a second portion configured to provide a status indication based on a state of the component. The example sensor device is configured to transmit the identifier and status indication to a control computer associated with a bioproces sing platform including the component.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: February 14, 2017
    Assignee: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Radislav A. Potyrailo, Klaus Gebauer, Kajsa Stridsberg-Friden, Timothy A. Wortley
  • Publication number: 20160379019
    Abstract: This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory chip (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written in sequence into the memory chip, so that the redundant information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
    Type: Application
    Filed: June 17, 2016
    Publication date: December 29, 2016
    Inventors: MANUEL NYFFELER, RADISLAV A. POTYRAILO, VINCENT F. PIZZI, WILLIAM G. MORRIS, GERARD J. GACH, VIJAY SINGH
  • Publication number: 20160244712
    Abstract: Provided herein are techniques for identification of viable and nonviable cells in a cell culture that include measuring a resonance impedance spectral response of at least one resonator in proximity to the cell culture and correlating the measured response to the concentration of viable cells in cell culture and/or the concentration of nonviable cells in cell culture.
    Type: Application
    Filed: February 16, 2016
    Publication date: August 25, 2016
    Inventors: Radislav A. Potyrailo, Victoria E. Cotero, Jon A. Dieringer, Thomas J. Erdenberger, Timothy A. Wortley
  • Patent number: 9373008
    Abstract: This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory chip (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written in sequence into the memory chip, so that the redundant information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: June 21, 2016
    Assignee: GE Healthcare Bioscience BioProcess Corp.
    Inventors: Manuel Nyffeler, Radislav A. Potyrailo, Vincent F. Pizzi, William G. Morris, Gerard J. Gach, Vijay Singh
  • Patent number: 9274071
    Abstract: Provided herein are techniques for identification of viable and nonviable cells in a cell culture that include measuring a resonance impedance spectral response of at least one resonator in proximity to the cell culture and correlating the measured response to the concentration of viable cells in cell culture and/or the concentration of nonviable cells in cell culture.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: March 1, 2016
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Radislav A. Potyrailo, Victoria E. Cotero, Jon A. Dieringer, Thomas J. Erdenberger, Timothy A. Wortley
  • Patent number: 9176083
    Abstract: A system includes a vessel system for a fluid, a sampling assembly and a resonant sensor system coupled to the sampling assembly. The resonant sensor system may include a subsystem that detects a set of signals from a resonant sensor system at a plurality of locations in the vessel. The resonant sensor system may also include a subsystem that converts the set of signals to values of a complex impedance spectrum for the plurality of locations and stores the values of the complex impedance spectrum and frequency values. A subsystem determines a fluid phase inversion point from the values of the complex impedance spectrum.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: November 3, 2015
    Assignee: General Electric Company
    Inventors: Cheryl Margaret Surman, William Chester Platt, William Guy Morris, Steven Go, Jon Albert Dieringer, Radislav A. Potyrailo
  • Publication number: 20150185173
    Abstract: Provided herein are techniques for identification of viable and nonviable cells in a cell culture that include measuring a resonance impedance spectral response of at least one resonator in proximity to the cell culture and correlating the measured response to the concentration of viable cells in cell culture and/or the concentration of nonviable cells in cell culture.
    Type: Application
    Filed: December 30, 2013
    Publication date: July 2, 2015
    Inventors: Radislav A. Potyrailo, Victoria E. Cotero, Jon A. Dieringer, Thomas J. Erdenberger, Timothy A. Wortley
  • Publication number: 20150137992
    Abstract: Methods, systems, and apparatus to monitor component status in a bioprocessing environment are disclosed and described. Certain examples provide a sensor device for a disposable bioprocessing component. The example sensor device includes a first portion affixed to the component, the first portion configured to provide an identifier associated with the component. The example sensor device also includes a second portion configured to provide a status indication based on a state of the component. The example sensor device is configured to transmit the identifier and status indication to a control computer associated with a bioproces sing platform including the component.
    Type: Application
    Filed: November 21, 2013
    Publication date: May 21, 2015
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Radislav A. Potyrailo, Klaus Gebauer, Kajsa Stridsberg-Friden, Timothy A. Wortley
  • Patent number: 8963684
    Abstract: This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written into the memory chip, so that the information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: February 24, 2015
    Assignee: GE Healthcare Bio-Sciences Corp
    Inventors: Manuel Nyffeler, Radislav A. Potyrailo, Vincent F. Pizzi, William G. Morris, Gerard J. Gach, Vijay Singh
  • Publication number: 20140090454
    Abstract: A sensor includes a resonant transducer, the resonant transducer being configured to determine the composition of an emulsion. The composition of the emulsion is determined by measuring the complex impedance spectrum values of the mixture of the emulsion and applying multivariate data analysis to the values.
    Type: Application
    Filed: September 28, 2012
    Publication date: April 3, 2014
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Cheryl Margaret Surman, William Chester Platt, William Guy Morris, Steven Go, Jon Albert Dieringer, Radislav A. Potyrailo
  • Publication number: 20140090451
    Abstract: A system includes a vessel system for a fluid, a sampling assembly and a resonant sensor system coupled to the sampling assembly. The resonant sensor system may include a subsystem that detects a set of signals from a resonant sensor system at a plurality of locations in the vessel. The resonant sensor system may also include a subsystem that converts the set of signals to values of a complex impedance spectrum for the plurality of locations and stores the values of the complex impedance spectrum and frequency values. A subsystem determines a fluid phase inversion point from the values of the complex impedance spectrum.
    Type: Application
    Filed: September 28, 2012
    Publication date: April 3, 2014
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Cheryl Margaret Surman, William Chester Platt, William Guy Morris, Steven Go, Jon Albert Dieringer, Radislav A. Potyrailo
  • Publication number: 20140076973
    Abstract: This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory chip (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written in sequence into the memory chip, so that the redundant information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: GE HEALTHCARE BIO-SCIENCES CORP.
    Inventors: MANUEL NYFFELER, RADISLAV A. POTYRAILO, VINCENT F. PIZZI, WILLIAM G. MORRIS, GERARD J. GACH, VIJAY SINGH
  • Patent number: 8653940
    Abstract: This invention provides a system and apparatus that is able to authenticate and prevent illegal manufacturing and unauthorized operation of disposable bioprocess components. This invention utilizes a ferro-electric random access memory chip (FRAM) chip to store error-correctable information on a RFID tag attached to the disposable bioprocess components, where the error-correctable information is written in sequence into the memory chip, so that the redundant information can remain in the chip when the RFID tag and disposable bioprocess component is gamma-sterilized. Also, this invention includes a method for authenticating the disposable bioprocess component that reduces liability in that a counterfeit poor quality disposable component is not used on the hardware so the user will not file an unjustified complaint.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: February 18, 2014
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Manuel Nyffeler, Radislav A. Potyrailo, Vincent F. Pizzi, William G. Morris, Gerard J. Gach, Vijay Singh
  • Patent number: 8647883
    Abstract: A method of quantitatively measuring the concentration of a chemical species in a sample solution with a sensor film. A hydrogel sensor film is prepared having a chemical composition comprising an indicator that changes its optical property in the ultra-violet, visible or near-infrared spectral range upon being exposed to the chemical species in the sample solution. The film is exposed to a fixed amount of the sample solution. The concentration of the chemical species in the sample solution is quantified using the average absorbance measured from the sensor film.
    Type: Grant
    Filed: September 13, 2010
    Date of Patent: February 11, 2014
    Assignee: General Electric Company
    Inventors: Radislav A. Potyrailo, Timothy M. Sivavec, Caibin Xiao, Theodore J. Cecconie, Lamyaa Hassib, Andrew M. Leach, David B. Engel
  • Patent number: 8587410
    Abstract: This invention provides a system for operating RFID tags on a single-use connector. The system includes: a first single-use connector configured to receive a first RFID tag and a second single-use connector configured to receive a second RFID tag. The invention also includes a reader placed close to the first RFID tag and the second RFID tag. The reader is configured to: determine if the first RFID tag and the second RFID tag are gamma sterilized; determine if the first RFID tag and the second RFID tag were previously used; determine if the first RFID tag and the second RFID tag are authentic; and determine if the first RFID tag matches with the second RFID tag.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: November 19, 2013
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Radislav Potyrailo, Vincent F. Pizzi, Hanno Ehring, Cheryl M. Surman, Klaus Gebauer, Mircea Georgescu