Patents by Inventor Rainer Endermann

Rainer Endermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzofuranyl -and benzothienyloxazolidinones
    Patent number: 5684023
    Abstract: The present invention relates to benzofuranyl- and benzothienyloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
    Type: Grant
    Filed: July 17, 1995
    Date of Patent: November 4, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bernd Riedl, Dieter Habich, Andreas Stolle, Hanno Wild, Rainer Endermann, Klaus Dieter Bremm, Hein-Peter Kroll, Harald Labischinski, Klaus Schaller, Hans-Otto Werling
  • 8-amino-10-(azabicycloalkyl)-pyrido?1,2,3-d,e!?1,3,4!benzoxadiazine derivatives
    Patent number: 5679675
    Abstract: The present invention relates to new 8-amino-10-(azabicycloalkyl)-pyrido?1,2,3-d,e!?1,3,4!benzoxadiazine derivatives of the general formula (I) ##STR1## in which the radicals R.sup.1 to R.sup.4, Z and X.sup.1 have the meaning given in the description, processes for their preparation and their use in antibacterial compositions.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: October 21, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Jaetsch, Burkhard Mielke, Uwe Petersen, Thomas Schenke, Klaus-Dieter Bremm, Rainer Endermann, Karl-Georg Metzger, Martin Scheer, Michael Stegemann, Heinz-Georg Wetzstein
  • Quinolone- and naphthyridonecarboxylic acid derivatives
    Patent number: 5679689
    Abstract: Disclosed are new quinolone- and naphthyridonecarboxyclic acid derivatives of the formula: ##STR1## wherein T represents a radical of the formula: ##STR2## and the other radicals are as disclosed herein, for example, the compound 7-(3a-amino-1,2,3,7a-tetrahydro-isoindol-2-yl)-1-cyclopropyl-6-fluoro-1,4- dihydro-8-methoxy-4-oxo-3-quinolinecarboxyclic acid, their salts, antibacterial compositions containing them, processes for their preparation, and methods of using them to combat bacterial infections. Disclosed also are intermediates useful in said processes of preparation.
    Type: Grant
    Filed: September 27, 1995
    Date of Patent: October 21, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Klaus-Dieter Bremm, Rainer Endermann
  • 5-vinyl-and 5-ethinyl-quinolone- and -naphthyridone-carboxylic acids
    Patent number: 5659038
    Abstract: The invention relates to new 5-vinyl- and 5-ethinylquinolone- and -naphthyridonecarboxylic acids, to processes for their preparation, and to antibacterial compositions and feed additives containing them.
    Type: Grant
    Filed: May 3, 1996
    Date of Patent: August 19, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Himmler, Uwe Petersen, Klaus-Dieter Bremm, Rainer Endermann, Michael Stegemann, Heinz-Georg Wetzstein
  • Preparation of 7-(3-amino- and 3-amino-methyl-1-pyrrolidinyl)-3-quinolonecarboxylic acids and -naphthyridonecarboxylic acids
    Patent number: 5648493
    Abstract: Process for the preparation of antibacterial compounds of the formula ##STR1## comprises condensing an oxo compound of the formula ##STR2## with an amino compound of the formula ##STR3## to produce a compound of the formula ##STR4## reacting the compound of the formula (III) with a compound of the formula ##STR5## to give a compound of the formula ##STR6## and then eliminating the amino-protective group ##STR7##
    Type: Grant
    Filed: June 19, 1991
    Date of Patent: July 15, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Andreas Krebs, Thomas Schenke, Klaus Grohe, Michael Schriewer, Ingo Haller, Karl Georg Metzger, Rainer Endermann, Hans-Joachim Zeiler
  • Cyclopentane- and -pentene-.beta.-amino acids
    Patent number: 5631291
    Abstract: The invention relates to cyclopentane- and -pentene-.beta.-amino acids, processes for their preparation and their use as medicaments.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: May 20, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Joachim Mittendorf, Franz Kunisch, Michael Matzke, Hans-Christian Militzer, Rainer Endermann, Karl G. Metzger, Klaus-Dieter Bremm, Manfred Plempel
  • 6-membered nitrogen-containing heteroaryl-oxazolidinones
    Patent number: 5627181
    Abstract: The invention relates to 6-membered nitrogen-containing heteroaryloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
    Type: Grant
    Filed: July 17, 1995
    Date of Patent: May 6, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Bernd Riedl, Dieter H abich, Andreas Stolle, Hanno Wild, Rainer Endermann, Klaus D. Bremm, Hein-Peter Kroll, Harald Labischinski, Klaus Schaller, Hans-Otto Werling
  • Preparation of 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl) quinolonecarboxylic and 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl naphthyridonecarboxylic acid derivatives
    Patent number: 5621105
    Type: Grant
    Filed: June 6, 1996
    Date of Patent: April 15, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Klaus Grohe, Klaus-Dieter Bremm, Rainer Endermann, Karl G. Metzger
  • 1,9-bridged thiazolo[3,2-a]quinoline derivatives
    Patent number: 5618815
    Abstract: The present invention relates to 1,9-bridged thiazolo[3,2-a]quinoline derivatives of the general formula (I) ##STR1## in which the substituents Z, X, R.sup.1 have the meaning given in the description, to processes for their preparation and to their use in antibacterial compositions.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: April 8, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Jaetsch, Werner Hallenbach, Thomas Himmler, Burkhard Mielke, Klaus D. Bremm, Rainer Endermann, Franz Pirro, Michael Stegemann, Heinz-Georg Wetzstein
  • 7-(1-pyrrolidinyl)-3-quinolone- and - naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives
    Patent number: 5607942
    Abstract: 7-(1-Pyrrolidinyl)-3-quinolone- and -naphthyridone-carboxylic acid derivatives as antibacterial agents and feed additives, of the formula ##STR1## in which X.sup.1 is halogen,X.sup.2 is hydrogen, halogen, amino or other radical,R.sup.1 is alkyl, cycloalkyl, optionally substituted phenyl or other radical,R.sup.2 is hydrogen, alkyl or a dioxolylmethyl radical,R.sup.3 is ##STR2## and A is N, CH, C-halogen, or the like, or forms a bridge with R.sup.1,and addition products thereof.
    Type: Grant
    Filed: March 20, 1995
    Date of Patent: March 4, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Andreas Krebs, Klaus Grohe, Michael Schriewer, Ingo Haller, Karl G. Metzger, Rainer Endermann, Hans-Joachim Zeiler
  • Quinolone-and naphthyridonecarboxylic acid derivatives
    Patent number: 5605910
    Abstract: The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a tricyclic amine radical, their salts, processes for their preparation and antibacterial compositions comprising these compounds.
    Type: Grant
    Filed: July 28, 1995
    Date of Patent: February 25, 1997
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Thomas Jaetsch, Stephan Bartel, Klaus D. Bremm, Rainer Endermann, Karl G. Metzger
  • 5-vinyl- and 5-ethinyl-quinolone- carboxylic acids
    Patent number: 5578604
    Abstract: The invention relates to new 5-vinyl- and 5-ethinyl-quinolone- and -naphthyridonecarboxylic acids, to processes for their preparation, and to antibacterial compositions and feed additives containing them.
    Type: Grant
    Filed: March 3, 1995
    Date of Patent: November 26, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Himmler, Uwe Petersen, Klaus-Dieter Bremm, Rainer Endermann, Michael Stegemann, Heinz-Georg Wetzstein
  • 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)quinolonecarboxylic and 7-(aminomethyl-oxa-7-aza-bicyclo[3.3.0]oct-7-yl naphthyridonecarboxylic acid derivatives
    Patent number: 5574161
    Abstract: The invention relates to novel derivatives of quinolone-carboxylic acid and naphthyridonecarboxylic acid which are substituted in the 7 position by a 1- (or 5-)amino-methyl-2- (or 3-)oxa-7-aza-bicyclo[3.3.0]oct-7-yl residue, their salts, processes for their preparation and antibacterial agents containing these compounds.
    Type: Grant
    Filed: October 7, 1994
    Date of Patent: November 12, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Klaus Grohe, Klaus-Dieter Bremm, Rainer Endermann, Karl G. Metzger
  • 7-isoindolinyl-naphthyridone derivatives, compositions and anti-bacterial use thereof
    Patent number: 5556979
    Abstract: The invention relates to novel quinolone derivatives and naphthyridone derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation and to antibacterial agents and feed additives containing them.
    Type: Grant
    Filed: September 10, 1993
    Date of Patent: September 17, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Philipps, Stephan Bartel, Andreas Krebs, Uwe Petersen, Thomas Schenke, Klaus-Dieter Bremm, Rainer Endermann, Karl G. Metzger, Burkhard Mielke
  • Derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthridonecarboxylic acid
    Patent number: 5545642
    Abstract: The invention relates to novel derivatives of 1-(2-fluorocyclopropyl)-quinolonecarboxylic acid and 1-(2-fluorocyclopropyl)-naphthyridonecarboxylic acid which are substituted in the 7 position by a 2,3,4,5,6,7-hexahydro-1H-pyrrolo[3,4-c]pyridin-2-yl or 1,2,3,4,5,6-hexahydropyrrolo[3,4-c]pyrrol-2-yl residue, to their salts, to a process for their preparation and to antibacterial agents containing these derivatives.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: August 13, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Schenke, Stefan B ohm, Rolf Grosser, Klaus D. Bremm, Rainer Endermann, Karl G. Metzger
  • Benzoxazolyl- and benzothiazolyloxazolidinones
    Patent number: 5529998
    Abstract: The invention relates to benzoxazolyl- and benzothiazolyloxazolidinones, processes for their preparation and their use as medicaments, in particular as antibacterial medicaments.
    Type: Grant
    Filed: July 27, 1995
    Date of Patent: June 25, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dieter Habich, Bernd Riedl, Martin Ruppelt, Andreas Stolle, Hanno Wild, Rainer Endermann, Klaus D. Bremm, Hein-Peter Kroll, Harald Labischinski, Klaus Schaller, Hans-Otto Werling
  • Pyrido[1,2,3-D,E] [1,3,4]benzoxadiazine derivatives
    Patent number: 5508278
    Abstract: Novel bactericidal pyrido[1,2,3-d,e,][1,3,4]benzoxadiazine derivatives of the formula (I) ##STR1## in which R.sup.1 is hydrogen or C.sub.1 -C.sub.4 -alkyl optionally substituted by hydroxyl or halogen,R.sup.2 independently of R.sup.1 is hydrogen or methyl,R.sup.3 is hydrogen or C.sub.1 -C.sub.4 -alkyl,R.sup.4 is hydrogen, C.sub.1 -C.sub.4 -alkyl optionally substituted by hydroxyl, methoxy, amino, methylamino or dimethylamino, or (5-methyl-2-oxo-1,3-dioxol-4-yl)-methyl,X.sup.
    Type: Grant
    Filed: August 26, 1994
    Date of Patent: April 16, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Thomas Jaetsch, Burkhard Mielke, Uwe Petersen, Thomas Philipps, Thomas Schenke, Klaus D. Bremm, Rainer Endermann, Karl G. Metzger, Martin Scheer, Michael Stegemann, Heinz-Georg Wetzstein
  • Quinolonecarboxylic acids
    Patent number: 5480879
    Abstract: The invention relates to novel derivatives of quinolonecarboxylic acid and naphthyridonecarboxylic acid which are linked to a .beta.-lactam antibiotic, to their salts, to processes for their preparation and to antibacterial agents containing these derivatives.
    Type: Grant
    Filed: October 1, 1993
    Date of Patent: January 2, 1996
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Wilfried Schrock, Dieter Habich, Andreas Krebs, Thomas Schenke, Thomas Philipps, Klaus Grohe, Rainer Endermann, Klaus-Dieter Bremm, Karl-Georg Metzger
  • 8-vinyl- and 9-ethinyl-quinolone-carboxylic acids
    Patent number: 5468742
    Abstract: The invention relates to new 8-vinyl- and 8-ethinylquinolonecarboxylic acids, process for their preparation, and antibacterial agents and feed additives containing them.
    Type: Grant
    Filed: November 1, 1993
    Date of Patent: November 21, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Thomas Himmler, Thomas Schenke, Andreas Krebs, Klaus Grohe, Klaus-Dieter Bremm, Karl G. Metzger, Rainer Endermann, Hans-Joachim Zeiler
  • 7-isoindolinyl-quinolone-carboxylic acid derivatives
    Patent number: 5464796
    Abstract: The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a partly hydrogenated isoindolinyl ring, processes for their preparation and antibacterial agents and feed additives containing these compounds.
    Type: Grant
    Filed: June 11, 1992
    Date of Patent: November 7, 1995
    Assignee: Bayer Aktiengesellschaft
    Inventors: Uwe Petersen, Andreas Krebs, Thomas Schenke, Franz Kunisch, Thomas Philipps, Klaus Grohe, Klaus-Dieter Bremm, Rainer Endermann, Karl-Georg Metzger, Ingo Haller, Hans-Joachim Zeiler