Patents by Inventor Rajani Adiga
Rajani Adiga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230407230Abstract: The present invention relates to cell free protein manufacturing, and more particularly, for integrating machine learning into a portable cell-free bioprocessing system for producing proteins with increased and consistent purity, potency and quality wherein such proteins are prepared on-demand and for point-of-care delivery.Type: ApplicationFiled: June 5, 2023Publication date: December 21, 2023Inventors: GOVIND RAO, YORDAN KOSTOV, BENJAMIN PUNSHON-SMITH, RAJANI ADIGA
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Patent number: 11685892Abstract: The present invention relates to cell free protein manufacturing, and more particularly, for integrating machine learning into a portable cell-free bioprocessing system for producing proteins with increased and consistent purity, potency and quality wherein such proteins are prepared on-demand and for point-of-care delivery.Type: GrantFiled: May 15, 2019Date of Patent: June 27, 2023Assignee: University of Maryland, Baltimore CountyInventors: Govind Rao, Yordan Kostov, Benjamin Punshon-Smith, Rajani Adiga
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Publication number: 20210299491Abstract: The present disclosure provides a method and a device for suppressing fire due to combustible gases generated from an energy storage unit. The device includes a substrate (102), a catalyst (103) coated on the substrate (102) and the catalyst coated substrate (101) placed with the energy storage unit for suppressing raging fire.Type: ApplicationFiled: March 19, 2021Publication date: September 30, 2021Inventors: KAYYANI C ADIGA, RAJANI ADIGA, Herbert Wayne Graves
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Publication number: 20210189322Abstract: The present invention relates to cell free protein manufacturing, and more particularly, for integrating machine learning into a portable cell-free bioprocessing system for producing proteins with increased and consistent purity, potency and quality wherein such proteins are prepared on-demand and for point-of-care delivery.Type: ApplicationFiled: May 15, 2019Publication date: June 24, 2021Inventors: GOVIND RAO, YORDAN KOSTOV, BENJAMIN PUNSHON-SMITH, RAJANI ADIGA
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Publication number: 20190232094Abstract: A device, composition, and a process for a hybrid blend of inert gas and mist produced for fire protection by local or total flooding. The method mixes ultrafine water mist, preferably less than 20 microns diameter produced by atomization and an inert gas such as nitrogen. A homogeneous hybrid composition discharges from a swirling flow mixer-injector device. The hybrid composition extinguishes a fire source in reduced time by simultaneous and synergistic cooling with the mist and inerting with the inert gas. After extinction oxygen remains at a safe level of 12.5-15% (V). The high-velocity inert gas flow of 35-75 mph velocity in the mixing-injector column formed by an exit in the mixer-injector device entrains the low-velocity mist flowing out of atomizer. The device creates a swirling, high-speed, and expanding flow of the hybrid composition inside the fire protection volume at ambient pressure.Type: ApplicationFiled: January 3, 2019Publication date: August 1, 2019Applicant: Nanomist Fire Safety, LLCInventors: Adiga C. Kayyani, Rajani Adiga, Herbert W. Graves
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Patent number: 10238761Abstract: The present invention is an improved method for decontamination of a space and an integrated device that completes the decontamination cycle extremely fast while still being compact, lightweight, simple to operate and easy to move as a single unit. The method of the present invention delivers less biocide than is used in prior art methods at a very high rate of flux, allows the biocide to reside in the space being decontaminated to achieve a predetermined kill level, and then aerates the space. Because a nominal amount of biocide is used, there is less biocide to remove from the space than in prior art methods thereby reducing the time required for aeration and shortening the downtime for safe entry of the facility.Type: GrantFiled: August 10, 2016Date of Patent: March 26, 2019Assignee: Nanomist Systems, LLCInventors: Kayyani C. Adiga, Rajani Adiga, Robert F. Hatcher, Jr.
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Patent number: 9533064Abstract: A mist generator is used to deliver a high throughput extremely fine mist comprising a biocide. Flows of evaporating hot gas mix turbulently and enhance forced heat and mass transfer between the very fine droplets and the hot gas to form a well-mixed premixed evaporator, resulting in high humidity vapor formation well inside a tube. The high relative humidity vapor with elevated temperature is then condensed as it exits the tube and disperses into the volume to be decontaminated as a condensed vapor cloud, but neither as a mist nor as a pure vapor depending on temperature and humidity of room environment. The condensed vapor cloud may evaporate or settle on the volume surfaces and contents, whereby both dry vapor and condensed vapor are applied into the volume for the killing process.Type: GrantFiled: July 18, 2013Date of Patent: January 3, 2017Assignee: Nanomist Systems, LLCInventors: Kayyani C. Adiga, Robert F. Hatcher, Rajani Adiga
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Patent number: 8790575Abstract: An apparatus and method are disclosed for improving the efficiency of an aerator which is used for removing residual biocide used for decontamination, sterilization, sanitation, or disinfection processes. The apparatus comprises an aerator assembly that produces an optimum air flow region and a high surface area catalyst panel. The method comprises utilizing the apparatus with optimizing gas flow rates, residence time of the contaminated gas within the catalyst panel, air flow pattern, air transport rate, cleaned air discharge pattern, and the nature and configuration of the catalyst.Type: GrantFiled: June 18, 2013Date of Patent: July 29, 2014Assignee: Nano Mist Systems, LLCInventors: Kayyani C. Adiga, Rajani Adiga, Robert F. Hatcher, Jr.
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Publication number: 20120125197Abstract: A decontamination apparatus is disclosed. The decontamination apparatus comprises a mist generator configured to generate a mist, a first conduit in fluid communication with the mist generator and configured to receive the mist, a stream movement device configured to move a stream, and a heating device configured to heat the stream moved by the stream movement device. The decontamination apparatus comprises a second conduit in fluid communication with the stream movement device and configured to receive the heated stream. The first conduit comprises a first outlet configured to pass the mist therethrough and the second conduit comprises a second outlet configured to pass the heated stream therethrough. The second outlet is positioned proximate to the first outlet. A portion of the mist evaporates into a vapor for decontamination of an environment when mixed with the heated stream outside of the first outlet, the second outlet, and the decontamination apparatus.Type: ApplicationFiled: November 22, 2010Publication date: May 24, 2012Applicant: Ethicon, Inc.Inventors: Szu-Min Lin, Robert C. Platt, JR., Robert G. Lukasik, Kayyani C. Adiga, Rajani Adiga, Robert F. Hatcher, JR.
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Patent number: 7834225Abstract: A method and device is presented for separating liquid mixtures using ultrasonic atomization and without subjecting the mixture to heat or thermal distillation. The process of ultrasonic separation does not involve liquid heating and saves up to 75% of the energy required as compared to thermal distillation. The method involves high throughput fixed bed atomizers with a specially designed carrier gas flow for aerosolization, extraction, and transport of mist. The mist richer in the desired component is then collected and condensed by electrostatic or other de-misting means. Repeated processes can achieve high separation efficiency. The efficiency of separation can be controlled by varying the ultrasonic frequency, power, and number of arrays, liquid surface tension and interfacial tension of mixtures.Type: GrantFiled: March 7, 2007Date of Patent: November 16, 2010Assignee: Nanomist Systems, LLCInventors: Kayyani C. Adiga, Rajani Adiga
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Publication number: 20100218959Abstract: A method and device for suppression of fires related to heating appliances, vent hoods and work benches through deployment of very fine mist droplets, preferably less 100 micron diameter, into the firebase. A low momentum, high mist loading fine mist stream is introduced about the firebase. Mist is discharged to the firebase through diffusers or swirl channels so that the mist surrounding the firebase will be entrained into the firebase to secure and suppress the fire. After the fire is suppressed, the fine mist is further discharged to the hot oil surface for cooling.Type: ApplicationFiled: August 25, 2009Publication date: September 2, 2010Applicant: Nanomist Systems, LLCInventors: Kayyani C. Adiga, Rajani Adiga, Robert F. Hatcher
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Patent number: 7326382Abstract: A method of sterilizing a site or contained volume includes providing an aqueous biocide solution containing a biocide agent such as hydrogen peroxide. A mist of reactive biocide droplets is generated by atomization at ambient pressure from the biocide solution and a flow of carrier medium or air is provided in communication with the mist. The flow of carrier medium is controlled to generate a biocide mist comprising a concentration of stable mist droplets within the carrier medium. By controlling aersolization, extraction and delivery of the stable mist droplets, a sufficient portion of the stable mist droplets for a sterilizing treatment of a designated site do not coalesce prior to treatment interaction with the treatment site. The process of formation, stabilization and extraction are done in-situ so that droplets do not coalesce during transport.Type: GrantFiled: March 20, 2003Date of Patent: February 5, 2008Assignee: Nanomist Systems, LLCInventors: Kayyani C. Adiga, Rajani Adiga
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Patent number: 7264773Abstract: The invention provides a method for generating a homogeneous aqueous mist solution containing a solvent such as water and a biocide agent such as chlorine dioxide, which would otherwise be unstable. The unstable biocide agent or chlorine dioxide is quickly dissolved or mixed with a mist of solvent causing the biocide agent to co-exist or co-mist therewith. The mist microencapsulates the biocide gas so that it does not decompose in the fumigation volume or space. The resulting homogenous mist solution provides a mist for delivering the biocide agent in a chemically stable form. Methods for mixing the separately generated mist and biocide gas include combining the mists in a Y-tube and then mixing the combination in a baffled mixing chamber, combining the mists in an area above their points of generation and then further mixing, and providing a series of mist generation units connected by a conduit for a carrier medium to pass to and connect the units and cause the mists to combine.Type: GrantFiled: May 2, 2003Date of Patent: September 4, 2007Assignee: Nanomist Systems, LLCInventors: Kayyani C. Adiga, Rajani Adiga
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Publication number: 20070193753Abstract: A method and device for suppression of fires related to heating appliances, vent hoods and work benches through deployment of very fine mist droplets, preferably less 100 micron diameter, into the firebase. A low momentum, high mist loading fine mist stream is introduced about the firebase. Mist is discharged to the firebase through diffusers or swirl channels so that the mist surrounding the firebase will be entrained into the firebase to secure and suppress the fire. After the fire is suppressed, the fine mist is further discharged to the hot oil surface for cooling.Type: ApplicationFiled: February 21, 2006Publication date: August 23, 2007Inventors: Kayyani Adiga, Rajani Adiga, Robert Hatcher
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Publication number: 20070193874Abstract: An improved method and device is accomplished for ethanol production using an in-line extraction of ethanol by ultrasonic atomization, thereby removing the effect of the ethanol inhibition factor that adversely affects the rate and yield. The in-line removal of ethanol as it is formed increases the fermentation rate, improves the yield and uses 20-25% of the energy required as compared to thermal distillation processes currently used. The improved method makes sure that ultrasonic vibration does not deactivate enzymes to any significant level. The elimination of the effect of the ethanol inhibition factor allows for a continuous fermentation process as opposed to the costly, time-consuming repeated batch processes.Type: ApplicationFiled: February 14, 2007Publication date: August 23, 2007Inventors: Kayyani Adiga, Rajani Adiga
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Publication number: 20060196681Abstract: An improved method and apparatus for producing an extremely fine micron and sub-micron size water mist using an electronic ultrasonic device that produces the mist at ambient-pressure and delivering the mist for application in suppressing fire. A piezoelectric transducer is arranged to produce a water mist having at least a portion of sub-micron size droplets. The water mist is produced by high frequency pressure waves or ultrasonic waves of predetermined or variable frequency, including frequencies which may exceed 2.5 MHz. The water mist is directed to a firebase to be self-entrained by the fire's flame. The momentum provided the water mist in directing the mist is minimized to enhance the ability of the fire to entrain the mist, and the flow of the carrier medium is usually directed tangentially about the water fountain creating the mist. Further, the throughput and concentration of the mist is controlled to ensure that the entrained mist will be sufficient to cool and suppress the fire.Type: ApplicationFiled: December 20, 2005Publication date: September 7, 2006Inventors: Kayyani Adiga, Rajani Adiga
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Patent number: 7090028Abstract: An improved method and apparatus for producing an extremely fine micron and sub-micron size water mist using an electronic ultrasonic device that produces the mist at ambient-pressure and delivering the mist for application in suppressing fire. A piezoelectric transducer is arranged to produce a water mist having at least a portion of sub-micron size droplets. The water mist is produced by high frequency pressure waves or ultrasonic waves of predetermined or variable frequency, including frequencies which may exceed 2.5 MHz. The water mist is directed to a firebase to be self-entrained by the fire's flame. The momentum provided the water mist in directing the mist is minimized to enhance the ability of the fire to entrain the mist, and the flow of the carrier medium is usually directed tangentially about the water fountain creating the mist. Further, the throughput and concentration of the mist is controlled to ensure that the entrained mist will be sufficient to cool and suppress the fire.Type: GrantFiled: September 19, 2002Date of Patent: August 15, 2006Assignee: Nanomist Systems, LLCInventors: Kayyani C. Adiga, Rajani Adiga
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Patent number: 6955063Abstract: A cooling method and apparatus including a mist-generating device is configured to generate a mist of droplets from water, dielectric liquids or any cooling liquids. The mist is produced having such volume, momentum, concentration and quality of scale so as to deter or avoid impingement or deposition of the mist droplets on a surface to be cooled or on surfaces within a heat dissipating system to be cooled. Effective cooling is provided by the high latent heat of vaporization of water or other suitable fluid, while surfaces normally subject to possible damage by wetting are protected from harmful contact from the fluid. Tangential flow technology and electronic ultrasonic atomizing devices may be used as one possible means to generate the required mist and control mist volume, momentum, concentration and quality. Other variables may be controlled to enhance the cooling of the mist, such as flow patterns and flow directions of the mist. Vaporized mist may be condensed and recovered.Type: GrantFiled: June 14, 2003Date of Patent: October 18, 2005Assignee: Nanomist Systems, LLCInventors: Kayyani C. Adiga, Rajani Adiga, Robert F. Hatcher, Jr.
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Patent number: 6883724Abstract: The present invention provides a method and device for production, extraction and delivery of an aerosol mist with ultrafine droplets. A high frequency wave generating device or other process generates very small particles or droplets from a reservoir of liquid or material to be atomized. A helical flow of a carrier gas medium such as air is directed into a container and creates a high throughput aerosol of air and fine droplets. The aerosol is delivered through a suitable outlet such as by deflecting the aerosol upwards and providing a tube centrally situated with respect to the helical flow such that the aerosol will discharge through the tube in high quantity of throughput and high quality of stable aerosol of very fine mist droplets. The methods described utilize in-situ extraction of fine mist droplets using helical flow behavior as opposed to forced convection ejection of mist or inertial separation of droplets by separators.Type: GrantFiled: September 19, 2002Date of Patent: April 26, 2005Assignee: Nanomist Systems, LLCInventors: Kayyani C. Adiga, Rajani Adiga, Robert F. Hatcher, Jr.
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Publication number: 20040250562Abstract: A cooling method and apparatus including a mist-generating device is configured to generate a mist of droplets from water, dielectric liquids or any cooling liquids. The mist is produced having such volume, momentum, concentration and quality of scale so as to deter or avoid impingement or deposition of the mist droplets on a surface to be cooled or on surfaces within a heat dissipating system to be cooled. Effective cooling is provided by the high latent heat of vaporization of water or other suitable fluid, while surfaces normally subject to possible damage by wetting are protected from harmful contact from the fluid.Type: ApplicationFiled: June 14, 2003Publication date: December 16, 2004Inventors: Kayyani C. Adiga, Rajani Adiga, Robert F. Hatcher