Patents by Inventor Ram Grossfeld

Ram Grossfeld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11344414
    Abstract: Within a delivery passage of a catheter, an elongated and flexible annuloplasty structure is transluminally advanced toward a heart of a subject while the annuloplasty structure is in a substantially linear configuration in which a distal end of the annuloplasty structure is closer than a proximal end of the annuloplasty structure to a distal opening of the catheter. Subsequently, the distal end of the annuloplasty structure is advanced, followed by the proximal end of the annuloplasty structure, out of the catheter and into an atrium of the heart. Within the atrium, the annuloplasty structure is transitioned toward a ring form by the distal end of the annuloplasty structure being brought towards the proximal end of the annuloplasty structure. While the annuloplasty structure remains in the ring form, the annuloplasty structure is placed against tissue of the annulus and is anchored to the tissue.
    Type: Grant
    Filed: April 14, 2021
    Date of Patent: May 31, 2022
    Assignee: Valtech Cardio Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Patent number: 11259924
    Abstract: Apparatuses, systems, and devices usable for annuloplasty are provided. These can include an annuloplasty system comprising a segment having a lumen therethrough, the segment being positionable in a vicinity of a surface of a heart valve of a heart. The system can include a tube having a distal portion that is movable through the lumen of the segment and a distal end passable through an opening in the segment that is in fluid communication with the lumen. One or more tissue anchors are deliverable through the tube, the tissue anchor(s) being shaped so as to define a tissue coupling element. The distal portion of the tube can be removably positioned within the lumen of the segment, and, while so positioned, to deploy the tissue coupling element from the distal end of the tube in order to penetrate the tissue coupling element into cardiac tissue. Other embodiments are also described.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: March 1, 2022
    Assignee: Valtech Cardio Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Publication number: 20210228356
    Abstract: Within a delivery passage of a catheter, an elongated and flexible annuloplasty structure is transluminally advanced toward a heart of a subject while the annuloplasty structure is in a substantially linear configuration in which a distal end of the annuloplasty structure is closer than a proximal end of the annuloplasty structure to a distal opening of the catheter. Subsequently, the distal end of the annuloplasty structure is advanced, followed by the proximal end of the annuloplasty structure, out of the catheter and into an atrium of the heart. Within the atrium, the annuloplasty structure is transitioned toward a ring form by the distal end of the annuloplasty structure being brought towards the proximal end of the annuloplasty structure. While the annuloplasty structure remains in the ring form, the annuloplasty structure is placed against tissue of the annulus and is anchored to the tissue.
    Type: Application
    Filed: April 14, 2021
    Publication date: July 29, 2021
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Publication number: 20200405484
    Abstract: Apparatuses, systems, and devices usable for valve repair are provided. These can include a valve repair system comprising an annuloplasty structure positionable in a vicinity of a surface of a heart valve of a heart. The system can include a tube or plurality of tubes. One or more tissue anchors are deliverable through the tube or plurality of tubes, the tissue anchor(s) being shaped so as to each define a tissue coupling element. The tissue coupling element(s) can be deployed from the distal end of the tube or plurality of tubes in order to penetrate the tissue coupling element into cardiac tissue. Other embodiments are also described.
    Type: Application
    Filed: September 15, 2020
    Publication date: December 31, 2020
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Publication number: 20190336288
    Abstract: Apparatuses, systems, and devices usable for annuloplasty are provided. These can include an annuloplasty system comprising a segment having a lumen therethrough, the segment being positionable in a vicinity of a surface of a heart valve of a heart. The system can include a tube having a distal portion that is movable through the lumen of the segment and a distal end passable through an opening in the segment that is in fluid communication with the lumen. One or more tissue anchors are deliverable through the tube, the tissue anchor(s) being shaped so as to define a tissue coupling element. The distal portion of the tube can be removably positioned within the lumen of the segment, and, while so positioned, to deploy the tissue coupling element from the distal end of the tube in order to penetrate the tissue coupling element into cardiac tissue. Other embodiments are also described.
    Type: Application
    Filed: July 18, 2019
    Publication date: November 7, 2019
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Patent number: 10363137
    Abstract: Apparatuses and devices usable for annuloplasty are provided. These can include a plurality of tissue anchors and an annuloplasty structure for placement on a heart valve annulus. The annuloplasty structure can include a plurality of compressible or adjustable subunits, and a plurality of anchor mounts alternately disposed with respect to the plurality of compressible/adjustable subunits. The anchor mounts are coupleable to the tissue anchors and can define a path for passage therethrough of a respective tissue anchor. The apparatuses and devices can be independently adjustable and can be adjustable for treating various sizes of patient annuli. Other embodiments are also described.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: July 30, 2019
    Assignee: Valtech Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Patent number: 10357366
    Abstract: Apparatuses and devices usable for annuloplasty are provided. These can include a plurality of helical tissue anchors and an annuloplasty structure for placement on a heart valve annulus. The annuloplasty structure can include a plurality of compressible or adjustable subunits, and a plurality of anchor mounts alternately disposed with respect to the plurality of compressible/adjustable subunits. The anchor mounts are coupleable to the helical anchors and can define a path for passage therethrough of a respective helical tissue anchor. The apparatuses and devices can be independently adjustable and can be adjustable for treating various sizes of patient annuli. Other embodiments are also described.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: July 23, 2019
    Assignee: Valtech Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Publication number: 20180263777
    Abstract: Apparatuses and devices usable for annuloplasty are provided. These can include a plurality of helical tissue anchors and an annuloplasty structure for placement on a heart valve annulus. The annuloplasty structure can include a plurality of compressible or adjustable subunits, and a plurality of anchor mounts alternately disposed with respect to the plurality of compressible/adjustable subunits. The anchor mounts are coupleable to the helical anchors and can define a path for passage therethrough of a respective helical tissue anchor. The apparatuses and devices can be independently adjustable and can be adjustable for treating various sizes of patient annuli. Other embodiments are also described.
    Type: Application
    Filed: May 18, 2018
    Publication date: September 20, 2018
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Publication number: 20180263776
    Abstract: Apparatuses and devices usable for annuloplasty are provided. These can include a plurality of tissue anchors and an annuloplasty structure for placement on a heart valve annulus. The annuloplasty structure can include a plurality of compressible or adjustable subunits, and a plurality of anchor mounts alternately disposed with respect to the plurality of compressible/adjustable subunits. The anchor mounts are coupleable to the tissue anchors and can define a path for passage therethrough of a respective tissue anchor. The apparatuses and devices can be independently adjustable and can be adjustable for treating various sizes of patient annuli. Other embodiments are also described.
    Type: Application
    Filed: May 18, 2018
    Publication date: September 20, 2018
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Patent number: 9974653
    Abstract: Apparatus is provided, including an intracardiac annuloplasty structure configured for placement on an annulus of a heart valve, a first rotatable ring coupled to the annuloplasty structure and a second rotatable ring coupled to the annuloplasty structure. The first and second rotatable rings are arranged such that the first rotatable ring is rotatable to contract the annuloplasty structure while the second rotatable ring remains stationary, and the second rotatable ring is rotatable to contract the annuloplasty structure while the first rotatable ring remains stationary. Other embodiments are also described.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: May 22, 2018
    Assignee: Valtech Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mousaiuf
  • Patent number: 9883943
    Abstract: Apparatus is provided, including a plurality of helical tissue anchors and an intracardiac annuloplasty structure defining a plane for placement on a heart valve annulus. The annuloplasty structure includes a plurality of compressible subunits, and a plurality of anchor mounts alternately disposed with respect to the plurality of compressible subunits. Each anchor mount (a) defines at least one opening for passage therethrough of a respective helical tissue anchor, (b) defines a path for passage therethrough of the helical tissue anchor, the path being aligned along an axis that is at a non-zero angle with respect to the plane of the annuloplasty structure, and (c) provides a structural element in the path for corkscrewing a distal portion of the helical tissue anchor therearound. Other embodiments are also described.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: February 6, 2018
    Assignee: Valtech Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mousaiuf
  • Patent number: 9872769
    Abstract: Apparatus is provided, including an intracardiac annuloplasty structure. A first adjustment member has an end at a first location at first portions of the annuloplasty structure that are opposite each other. A second adjustment member has an end at a second location at the second portions of the annuloplasty structure that are opposite each other. The annuloplasty structure, the first-adjustment-member end, and the second-adjustment-member end are disposed within a catheter during delivery. After delivery, the first-adjustment-member end is moveable with respect to the annuloplasty structure toward and away from a plane of the annuloplasty structure to adjust a relative disposition of the first portions, and the second-adjustment-member end is moveable independently of the first-adjustment-member end and with respect to the annuloplasty structure toward and away from the plane to adjust a relative disposition of the second portions. Other embodiments are also described.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: January 23, 2018
    Assignee: Valtech Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mousaiuf
  • Publication number: 20170000609
    Abstract: Apparatus is provided, including an intracardiac annuloplasty structure. A first adjustment member has an end at a first location at first portions of the annuloplasty structure that are opposite each other. A second adjustment member has an end at a second location at the second portions of the annuloplasty structure that are opposite each other. The annuloplasty structure, the first-adjustment-member end, and the second-adjustment-member end are disposed within a catheter during delivery. After delivery, the first-adjustment-member end is moveable with respect to the annuloplasty structure toward and away from a plane of the annuloplasty structure to adjust a relative disposition of the first portions, and the second-adjustment-member end is moveable independently of the first-adjustment-member end and with respect to the annuloplasty structure toward and away from the plane to adjust a relative disposition of the second portions. Other embodiments are also described.
    Type: Application
    Filed: May 2, 2016
    Publication date: January 5, 2017
    Applicant: VALTECH CARDIO, LTD.
    Inventors: Amir GROSS, Iftah BEINART, Eran MILLER, Oz CABIRI, Eliahu ELIACHAR, Nir LILACH, Ram GROSSFELD, Dmitry GOLOM, Gideon MEYER-BRODNITZ, Arnon MOUSAIUF
  • Publication number: 20160361168
    Abstract: Apparatus is provided, including a plurality of helical tissue anchors and an intracardiac annuloplasty structure defining a plane for placement on a heart valve annulus. The annuloplasty structure includes a plurality of compressible subunits, and a plurality of anchor mounts alternately disposed with respect to the plurality of compressible subunits. Each anchor mount (a) defines at least one opening for passage therethrough of a respective helical tissue anchor, (b) defines a path for passage therethrough of the helical tissue anchor, the path being aligned along an axis that is at a non-zero angle with respect to the plane of the annuloplasty structure, and (c) provides a structural element in the path for corkscrewing a distal portion of the helical tissue anchor therearound. Other embodiments are also described.
    Type: Application
    Filed: August 29, 2016
    Publication date: December 15, 2016
    Applicant: VALTECH CARDIO, LTD.
    Inventors: Amir GROSS, Iftah BEINART, Eran MILLER, Oz CABIRI, Eliahu ELIACHAR, Nir LILACH, Ram GROSSFELD, Dmitry GOLOM, Gideon MEYER-BRODNITZ, Arnon MOUSAIUF
  • Publication number: 20160361169
    Abstract: Apparatus is provided, including an intracardiac annuloplasty structure configured for placement on an annulus of a heart valve, a first rotatable ring coupled to the annuloplasty structure and a second rotatable ring coupled to the annuloplasty structure. The first and second rotatable rings are arranged such that the first rotatable ring is rotatable to contract the annuloplasty structure while the second rotatable ring remains stationary, and the second rotatable ring is rotatable to contract the annuloplasty structure while the first rotatable ring remains stationary. Other embodiments are also described.
    Type: Application
    Filed: August 29, 2016
    Publication date: December 15, 2016
    Applicant: VALTECH CARDIO, LTD.
    Inventors: Amir GROSS, Iftah BEINART, Eran MILLER, Oz CABIRI, Eliahu ELIACHAR, Nir LILACH, Ram GROSSFELD, Dmitry GOLOM, Gideon MEYER-BRODNITZ, Arnon MOUSAIUF
  • Patent number: 9351830
    Abstract: A method for performing an annuloplasty includes positioning an annuloplasty ring structure along an atrial surface of an annulus of a heart valve. While a distal portion of a tube is longitudinally advanced through a channel of the ring structure, it faces a first portion of tissue of the annulus. A first tissue anchor is anchored to the first portion of tissue, from within the channel, while the distal end of the tube faces the first portion of the tissue. After moving the distal portion of the tube to a second portion of the structure, the second portion of the structure is anchored to a second portion of tissue by anchoring a second tissue anchor to the second portion of the tissue while the distal end of the tube faces the second portion of the tissue. Other embodiments are also described.
    Type: Grant
    Filed: November 24, 2014
    Date of Patent: May 31, 2016
    Assignee: VALTECH CARDIO, LTD.
    Inventors: Amir Gross, Iftah Beinart, Eran Miller, Oz Cabiri, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Patent number: 9192472
    Abstract: Apparatus is provided, including a tube (421) shaped to define a tube lumen at least one implant (100) reversibly coupled to the tube (421), and configured for implantation within a body of a patient. The apparatus also comprises two or more longitudinal guide members (470) disposed at least in part along a distal portion of the tube (421), the longitudinal guide members (470) having distal portions thereof configured to be reversibly coupled to the implant (100), and arranged such that application of a force to a first one of the longitudinal guide members (470) steers the distal portion of the tube (421) toward a first location along the implant (100), and application of a force to a second one of the longitudinal guide members (470) steers the distal portion of the tube (421) toward a second location along the implant (100). Other embodiments are also described.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: November 24, 2015
    Assignee: Valtec Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Patent number: 9155620
    Abstract: Apparatus is provided, including a tube (421) shaped to define a tube lumen at least one implant (100) reversibly coupled to the tube (421), and configured for implantation within a body of a patient. The apparatus also comprises two or more longitudinal guide members (470) disposed at least in part along a distal portion of the tube (421), the longitudinal guide members (470) having distal portions thereof configured to be reversibly coupled to the implant (100), and arranged such that application of a force to a first one of the longitudinal guide members (470) steers the distal portion of the tube (421) toward a first location along the implant (100), and application of a force to a second one of the longitudinal guide members (470) steers the distal portion of the tube (421) toward a second location along the implant (100). Other embodiments are also described.
    Type: Grant
    Filed: June 15, 2009
    Date of Patent: October 13, 2015
    Assignee: Valtec Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf
  • Publication number: 20150081014
    Abstract: A method for performing an annuloplasty includes positioning an annuloplasty ring structure along an atrial surface of an annulus of a heart valve. While a distal portion of a tube is longitudinally advanced through a channel of the ring structure, it faces a first portion of tissue of the annulus. A first tissue anchor is anchored to the first portion of tissue, from within the channel, while the distal end of the tube faces the first portion of the tissue. After moving the distal portion of the tube to a second portion of the structure, the second portion of the structure is anchored to a second portion of tissue by anchoring a second tissue anchor to the second portion of the tissue while the distal end of the tube faces the second portion of the tissue. Other embodiments are also described.
    Type: Application
    Filed: November 24, 2014
    Publication date: March 19, 2015
    Applicant: VALTECH CARDIO, LTD.
    Inventors: Amir GROSS, Iftah BEINART, Eran MILLER, Oz CABIRI, Eliahu ELIACHAR, Nir LILACH, Ram GROSSFELD, Dmitry GOLOM, Gideon MEYER-BRODNITZ, Arnon MOSAIUF
  • Patent number: 8926695
    Abstract: Apparatus is provided for repairing a valve of a patient, the valve including an annulus and at least first and second leaflets. The apparatus includes at least a first discrete segment and a second discrete segment of an annuloplasty structure, each segment being shaped to provide a respective lateral wall, each lateral wall being shaped to define at least one lumen of the respective segment. The apparatus further includes at least a first and a second control wire, each control wire configured for sliding advancement through both the first and second segments. The first control wire is configured to control a relative disposition of a first end of the first segment and a first end of the second segment. The second control wire is configured to control a relative disposition of a second end of the first segment and a second end of the second segment. Other embodiments are also described.
    Type: Grant
    Filed: December 5, 2007
    Date of Patent: January 6, 2015
    Assignee: ValTech Cardio, Ltd.
    Inventors: Amir Gross, Iftah Beinart, Eliahu Eliachar, Nir Lilach, Ram Grossfeld, Dmitry Golom, Gideon Meyer-Brodnitz, Arnon Mosaiuf