Patents by Inventor Ramón Berenguer Maimó

Ramón Berenguer Maimó has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6723852
    Abstract: The method for obtaining derivatives of [[(pyridil substituted)methyl]thio]benzomidazol (I), where each of R1, R3 and R4, independently of each other, is hydrogen, an alkyl, alkoxy or fluorinated alkoxy of 1 to 6 carbon atoms, and R2 is nitro, halogen, alkoxy or halogenated alkoxy of 1 to 6 carbon atoms, or a group —OR—(CH2)n—OR8, where n is an integer between 1 and 6 and R8 represents hydrogen or an alkyl group with 1 to 6 carbon atoms, which involves (a) reacting an N-oxide of a methylpyridine with an anhydride of activated carboxylic acid or of sulfonic acid, and (b) reacting the intermediate formed in stage (a) with a corresponding mercaptobenzomidazol. The compounds (I) are useful in the synthesis of derivatives of [[(pyridil substituted)methyl]sulfinyl]benzomidazol, such as omeprazol, lansoprazol, rabeprazol or pantoprazol.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: April 20, 2004
    Assignee: Esteve Quimica, S.A.
    Inventor: Ramon Berenguer Maimo
  • Patent number: 6603009
    Abstract: The present invention relates to a procedure for the oxidation of a thioether group to a sulfoxide group, with aqueous sodium percarbonate in the presence of a molybdenum salt as a catalyst. The procedure is of application to oxidize the thioether group of a compound (I), where R1 is a C1-C6 alkyl, a halogenated C1-C6 alkyl, or —(CH2)n—OR9, where n is an integer between 1 and 6 and R9 is H or a C1-C6 alkyl; R2, R3, R4, R5, R6 and R8, independently form each other represent H, a C1-C6 alkyl, or C1-C6 alkoxy; and R7 is H, a C1-C6 alkyl, a C1-C6 alkoxy or a C1-C6 fluorinated alkoxy, in order to obtain the sulfinyl derivative (II).
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: August 5, 2003
    Assignee: Esteve Quimica, S.A.
    Inventors: Ramon Berenguer Maimo, Julio Campon Pardo, Laura Coppi
  • Publication number: 20030036656
    Abstract: The method for obtaining derivatives of [[(pyridil substituted)methyl]thio]benzomidazol (I), where each of R1, R3 and R4, independently of each other, is hydrogen, an alkyl, alkoxy or fluorinated alkoxy of 1 to 6 carbon atoms, and R2 is nitro, halogen, alkoxy or halogenated alkoxy of 1 to 6 carbon atoms, or a group —OR—(CH2)n—OR8, where n is an integer between 1 and 6 and R8 represents hydrogen or an alkyl group with 1 to 6 carbon atoms, which involves (a) reacting an N-oxide of a methylpyridine with an anhydride of activated carboxylic acid or of sulfonic acid, and (b) reacting the intermediate formed in stage (a) with a corresponding mercaptobenzomidazol. The compounds (I) are useful in the synthesis of derivatives of [[(pyridil substituted)methyl]sulfinyl]benzomidazol, such as omeprazol, lansoprazol, rabeprazol or pantoprazol.
    Type: Application
    Filed: August 20, 2002
    Publication date: February 20, 2003
    Inventor: Ramon Berenguer Maimo
  • Publication number: 20030028030
    Abstract: The present invention relates to a procedure for the oxidation of a thioether group to a sulfoxide group, with aqueous sodium percarbonate in the presence of a molybdenum salt as a catalyst. The procedure is of application to oxidize the thioether group of a compound (I), where R1 is a C1-C6 alkyl, a halogenated C1-C6 alkyl, or —(CH2)n—OR9, where n is an integer between 1 and 6 and R9 is H or a C1-C6 alkyl; R2, R3, R4, R5, R6 and R8, independently form each other represent H, a C1-C6 alkyl, or C1-C6 alkoxy; and R7 is H, a C1-C6 alkyl, a C1-C6 alkoxy or a C1-C6 fluorinated alkoxy, in order to obtain the sulfinyl derivative (II).
    Type: Application
    Filed: August 20, 2002
    Publication date: February 6, 2003
    Inventors: Ramon Berenguer Maimo, Laura Coppi