Patents by Inventor Ramalinga M. Dharanipragada

Ramalinga M. Dharanipragada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8163751
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) wherein R1-R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1-C3-alkyl), B is CH2 or CH—(C1-C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: April 24, 2012
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Hartmut Strobel, Paulus Wohlfart, Alena Safarova, Armin Walser, Teri Suzuki, Karl Schönafinger, Ramalinga M. Dharanipragada
  • Patent number: 7928231
    Abstract: Thienopyrazoles of formula I, their preparation, pharmaceutical compositions comprising these compounds, and their pharmaceutical uses in the treatment of disease states capable of being modulated by the inhibition of the protein kinases, in particular interleukin-2 inducible tyrosine kinase (ITK).
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: April 19, 2011
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: John Gerard Jurcak, Matthieu Barrague, Timothy Alan Gillespy, Michael Louis Edwards, Kwon Yon Musick, Philip Marvin Weintraub, Yan Du, Ramalinga M. Dharanipragada, Ashfaq Ahmad Parkar
  • Publication number: 20100183712
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) wherein R1-R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1-C3-alkyl), B is CH2 or CH—(C1-C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description.
    Type: Application
    Filed: March 29, 2010
    Publication date: July 22, 2010
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Hartmut STROBEL, Paulus WOHLFART, Alena SAFAROVA, Armin WALSER, Teri SUZUKI, Karl SCHÖNAFINGER, Ramalinga M. DHARANIPRAGADA
  • Patent number: 7713963
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) wherein R1—R4 have the meanings given in the description, A is CH2, CHOH or CH—(C1-C3-alkyl), B is CH2 or CH—(C1-C3-alkyl), and R5 is an aryl or heteroaryl group, possibly substituted by the substituents listed in the description.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: May 11, 2010
    Assignee: sanofi-aventis Deutschland GmbH
    Inventors: Hartmut Strobel, Paulus Wohlfart, Alena Safarova, Armin Walser, Teri Suzuki, Karl Schoenafinger, Ramalinga M. Dharanipragada
  • Publication number: 20100056514
    Abstract: Thienopyrazoles, their preparation, pharmaceutical compositions comprising these compounds, and their pharmaceutical uses in the treatment of disease states capable of being modulated by the inhibition of the protein kinases, in particular interleukin-2 inducible tyrosine kinase (ITK).
    Type: Application
    Filed: March 26, 2009
    Publication date: March 4, 2010
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: John Gerard JURCAK, Matthieu BARRAGUE, Timothy Alan GILLESPY, Michael Louis EDWARDS, Kwon Yon MUSICK, Philip Marvin WEINTRAUB, Yan DU, Ramalinga M. DHARANIPRAGADA, Ashfaq Ahmad PARKAR
  • Patent number: 7518000
    Abstract: Thienopyrazoles of formula I, their preparation, pharmaceutical compositions comprising these compounds, and their pharmaceutical uses in the treatment of disease states capable of being modulated by the inhibition of the protein kinases, in particular interleukin-2 inducible tyrosine kinase (ITK).
    Type: Grant
    Filed: March 6, 2006
    Date of Patent: April 14, 2009
    Assignee: Aventis Pharmaceuticals, Inc.
    Inventors: John Gerald Jurcak, Matthieu Barrague, Timothy Alan Gillespy, Michael Louis Edwards, Kwon Yon Musick, Phillip Marvin Weintraub, Yan Du, Ramalinga M. Dharanipragada, Ashfaq Ahmed Parkar
  • Patent number: 7202278
    Abstract: A method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan- 2-yl benzamide according to the formula (I) to the said mammal.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: April 10, 2007
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • Patent number: 7169925
    Abstract: This invention discloses and claims a new class of indole derivatives for use in treating allergy, asthma, rhinitis, dermatitis, B-cell lymphomas, tumors and diseases associated with bacterial, rhinovirus or respiratory syncytial virus (RSV) infections. It has now been found that the compounds of this invention are capable of modulating T helper (Th) cells, Th1/Th2, and thereby capable of inhibiting the transcription of interleukin-4 (IL-4) message, IL-4 release or IL-4 production.
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: January 30, 2007
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Gregory H. Merriman, Philip M. Weintraub, Jeffrey S. Sabol, Ramalinga M. Dharanipragada, Nicholas J. Hrib, John G. Jurcak, Alexandre Gross, Brian Whiteley, Kwon Yon Musick, Joseph T. Klein
  • Patent number: 6953788
    Abstract: The present invention relates to certain novel 3-mercaptoacetylamino-1,5-substituted-2-oxo-azepan derivatives useful as inhibitors of matrix metalloproteinase. Pharmaceutical compositions containing said compounds as well as methods of treating various disease states responding to inhibition of matrix metalloproteinase are also claimed herein.
    Type: Grant
    Filed: December 19, 1997
    Date of Patent: October 11, 2005
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Alan M. Warshawsky, Joseph T. Tsay, Michael J. Janusz, Jian Shen, Gary A. Flynn, Ramalinga M. Dharanipragada, Joseph P. Burkhart, Douglas W. Beight, Meena V. Patel
  • Patent number: 6812253
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) to the said mammal.
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: November 2, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • Publication number: 20040019114
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) 1
    Type: Application
    Filed: July 22, 2003
    Publication date: January 29, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • Publication number: 20040010029
    Abstract: This invention discloses and claims a new class of indole derivatives for use in treating allergy, asthma, rhinitis, dermatitis, B-cell lymphomas, tumors and diseases associated with bacterial, rhinovirus or respiratory syncytial virus (RSV) infections. It has now been found that the compounds of this invention are capable of modulating T helper (Th) cells, Th1/Th2, and thereby capable of inhibiting the transcription of interleukin-4 (IL-4) message, IL-4 release or IL-4 production.
    Type: Application
    Filed: April 23, 2003
    Publication date: January 15, 2004
    Inventors: Gregory H. Merriman, Philip M. Weintraub, Jeffrey S. Sabol, Ramalinga M. Dharanipragada, Nicholas J. Hrib, John G. Jurcak, Alexandre Gross, Brian Whiteley, Kwon Yon Musick, Joseph T. Klein
  • Patent number: 6617359
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) to the said mammal.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: September 9, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel
  • Publication number: 20030055093
    Abstract: The present invention relates to acylated indanyl amines according to the general formula (I) 1
    Type: Application
    Filed: February 13, 2002
    Publication date: March 20, 2003
    Inventors: Hartmut Strobel, Paulus Wohlfart, Alena Safarova, Armin Walser, Teri Suzuki, Karl Schonafinger, Ramalinga M. Dharanipragada
  • Publication number: 20030022939
    Abstract: The present invention relates to the method of stimulating the expression of endothelial NO-synthase in a mammal, which method comprises administering a physiologically active amount of 4-fluoro-N-indan-2-yl benzamide according to the formula (I) 1
    Type: Application
    Filed: February 13, 2002
    Publication date: January 30, 2003
    Inventors: Paulus Wohlfart, Teri Suzuki, Ramalinga M. Dharanipragada, Alena Safarova, Armin Walser, Hartmut Strobel